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Published in: World Journal of Surgical Oncology 1/2017

Open Access 01-12-2017 | Case report

Primary carcinoma of the cystic duct: a case report and review of classifications

Authors: Lovenish Bains, Daljit Kaur, Arun Kumar Kakar, Aman Batish, Seema Rao

Published in: World Journal of Surgical Oncology | Issue 1/2017

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Abstract

Background

The incidence of extrahepatic bile duct malignancies is about 2–3.6% of all gastrointestinal malignancies. Primary carcinoma of cystic duct is a rare condition comprising a fraction of all extrahepatic bile duct malignancies with less than 70 cases reported worldwide. Majority of these cases were reported from East Asia. There is paucity in such case being reported from Indian subcontinent. We present a case of primary carcinoma of the cystic duct encountered during laparoscopic cholecystectomy.

Case presentation

A 65-year-old lady presented to us with symptomatic gall stone disease. Investigations revealed a distended gall bladder with multiple stones. Patient was taken up for laparoscopic cholecystectomy, during surgery a stony hard structure was found at cystic duct-common bile duct junction which was not amenable for clear dissection. Procedure was converted to open, and the patient underwent cholecystectomy with resection of common bile duct with Roux-en-Y hepaticojejunostomy and regional lymphadenectomy. Histopathological findings revealed it to be moderately differentiated adenocarcinoma of the cystic duct.

Conclusion

Primary carcinoma of cystic duct is a rare condition where early diagnosis can be difficult and if accidentally detected may add to surgeon’s dilemma. Proper surgery with en-bloc resection of gallbladder, cystic duct, common bile duct, and regional lymphadenectomy is the mainstay of treatment. The prognosis of carcinoma of cystic duct is better than extrahepatic bile duct malignancies. The old classification system has outlived its time and is more rigid in definition which is not practical in advanced cases; the new classification systems of this century offer better insight into understanding the tumor characteristics and prognosis.
Literature
2.
go back to reference Ozden I, Kamiya J, Nagino M, Uesaka K, Oda K, Sano T, Kamiya S, Nimura Y. Cystic duct carcinoma: a proposal for a new “working definition”. Langenbecks Arch Surg. 2003;387(9–10):337–42.PubMed Ozden I, Kamiya J, Nagino M, Uesaka K, Oda K, Sano T, Kamiya S, Nimura Y. Cystic duct carcinoma: a proposal for a new “working definition”. Langenbecks Arch Surg. 2003;387(9–10):337–42.PubMed
3.
go back to reference Kim WC, Lee DH, Ahn SI, Kim JM. A case of cystic duct carcinoma treated with surgery and adjuvant radiotherapy: a proposal for new classification. J Gastrointestin Liver Dis. J Gastrointestin Liver Dis. 2007;16(4):437–40.PubMed Kim WC, Lee DH, Ahn SI, Kim JM. A case of cystic duct carcinoma treated with surgery and adjuvant radiotherapy: a proposal for new classification. J Gastrointestin Liver Dis. J Gastrointestin Liver Dis. 2007;16(4):437–40.PubMed
6.
go back to reference Baraka A, al Mokhtar NY, Madda JP, Amirrad M, Asfar S. Primary carcinoma of the cystic duct causing obstructive jaundice. J R Soc Med. 1990;83(11):746–7.PubMedPubMedCentral Baraka A, al Mokhtar NY, Madda JP, Amirrad M, Asfar S. Primary carcinoma of the cystic duct causing obstructive jaundice. J R Soc Med. 1990;83(11):746–7.PubMedPubMedCentral
7.
go back to reference Phillips SJ, Estrin J. Primary adenocarcinoma in a cystic duct stump. Report of a case and review of the literature. Arch Surg. 1969;98:225–7.CrossRefPubMed Phillips SJ, Estrin J. Primary adenocarcinoma in a cystic duct stump. Report of a case and review of the literature. Arch Surg. 1969;98:225–7.CrossRefPubMed
8.
go back to reference Chan KM, Yeh TS, Tseng JH, Liu NJ, Jan YY, Chen MF. Clinicopathological analysis of cystic duct carcinoma. Hepatogastroenterology. 2005;52(63):691–4.PubMed Chan KM, Yeh TS, Tseng JH, Liu NJ, Jan YY, Chen MF. Clinicopathological analysis of cystic duct carcinoma. Hepatogastroenterology. 2005;52(63):691–4.PubMed
10.
go back to reference Sato M, Watanabe Y, Kikkawa H, Kohtani T, Suzuki H, Nezu K, et al. Carcinoma of the cystic duct associated with pancreaticobiliary maljunction. J Gastroenterol. 2001;36(4):276–80.CrossRefPubMed Sato M, Watanabe Y, Kikkawa H, Kohtani T, Suzuki H, Nezu K, et al. Carcinoma of the cystic duct associated with pancreaticobiliary maljunction. J Gastroenterol. 2001;36(4):276–80.CrossRefPubMed
11.
go back to reference Chijiiwa K, Torisu M. Primary carcinoma of the cystic duct. J Clin Gastroenterol. 1993;16(4):309–13.CrossRefPubMed Chijiiwa K, Torisu M. Primary carcinoma of the cystic duct. J Clin Gastroenterol. 1993;16(4):309–13.CrossRefPubMed
13.
14.
15.
go back to reference Kubota K, Kakuta Y, Inayama Y, Yoneda M, Abe Y, Inamori M, et al. Clinicopathologic study of resected cases of primary carcinoma of the cystic duct. Hepatogastroenterology. 2008;55(85):1174–8.PubMed Kubota K, Kakuta Y, Inayama Y, Yoneda M, Abe Y, Inamori M, et al. Clinicopathologic study of resected cases of primary carcinoma of the cystic duct. Hepatogastroenterology. 2008;55(85):1174–8.PubMed
16.
go back to reference He P, Shi JS, Chen WK, Wang ZR, Ren H, Li H. Multivariate statistical analysis of clinicopathologic factors influencing survival of patients with bile duct carcinoma. World J Gastroenterol. 2002;8:943–6.CrossRefPubMedPubMedCentral He P, Shi JS, Chen WK, Wang ZR, Ren H, Li H. Multivariate statistical analysis of clinicopathologic factors influencing survival of patients with bile duct carcinoma. World J Gastroenterol. 2002;8:943–6.CrossRefPubMedPubMedCentral
Metadata
Title
Primary carcinoma of the cystic duct: a case report and review of classifications
Authors
Lovenish Bains
Daljit Kaur
Arun Kumar Kakar
Aman Batish
Seema Rao
Publication date
01-12-2017
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2017
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-016-1073-4

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