Skip to main content
Top
Published in: Health and Quality of Life Outcomes 1/2018

Open Access 01-12-2018 | Research

EQ-5D-5L norms for the urban Chinese population in China

Authors: Zhihao Yang, Jan Busschbach, Gordon Liu, Nan Luo

Published in: Health and Quality of Life Outcomes | Issue 1/2018

Login to get access

Abstract

Background

To generate Chinese population norms for the EQ-5D-5L dimensions, EQ-VAS (Visual Analogue Scale) scores and EQ-5D-5L index scores, stratified by gender and age. The EQ-5D is a widely used generic health-related quality of life instrument to describe population health and health outcomes in clinical trials and health economic evaluations. Currently, there are no EQ-5D-5L population norms for China.

Methods

This norm study utilized the data collected in an EQ-5D-5L valuation study in China between December 2012 and January 2013. In the valuation study, respondents were asked to report their own health states using the EQ-5D-5L descriptive system and the EQ-VAS. Respondents’ demographic information was also collected. The EQ index score was calculated using the EQ-5D-5L value set based on the Chinese urban population. Norm scores were reported by important demographic variables.

Results

The mean EQ-VAS scores ranged between 88.3 for males of < 19 years and 82.9 for females of 60–69 years. Contrary to other population studies, females reported higher EQ-VAS scores than males in every age group except for 20–29 years. The mean EQ-5D-5L index values ranged from 0.912 for females of > 70 years to 0.971 for females of 30–39 years. Respondents reported more problems in the dimensions ‘pain/discomfort’ and ‘anxiety/depression’ than in the dimensions ‘mobility’, ‘self-care’ and ‘usual activities’ in all age groups.

Conclusions

The population norm scores for the EQ-5D can be used as reference values for comparative purposes in future Chinese studies. Further research into rural and/or a more representative population is warranted.
Literature
1.
go back to reference Szende A, Janssen B, Cabases JM. Self-reported population health: an international perspective based on EQ-5D. New York: Springer; 2014.CrossRef Szende A, Janssen B, Cabases JM. Self-reported population health: an international perspective based on EQ-5D. New York: Springer; 2014.CrossRef
2.
go back to reference Luo N, Li M, Liu GG, Lloyd A, de Charro F, Herdman M. Developing the Chinese version of the new 5-level EQ-5D descriptive system: the response scaling approach. Qual Life Res. 2013;22(4):885–90.CrossRef Luo N, Li M, Liu GG, Lloyd A, de Charro F, Herdman M. Developing the Chinese version of the new 5-level EQ-5D descriptive system: the response scaling approach. Qual Life Res. 2013;22(4):885–90.CrossRef
3.
go back to reference Luo N, Liu G, Li M, Guan H, Jin X, Rand-Hendriksen K. Estimating an EQ-5D-5L value set for China. Value Health. 2017;20(4):662–9.CrossRef Luo N, Liu G, Li M, Guan H, Jin X, Rand-Hendriksen K. Estimating an EQ-5D-5L value set for China. Value Health. 2017;20(4):662–9.CrossRef
4.
go back to reference Feng Y, Devlin N, Herdman M. Assessing the health of the general population in England: how do the three- and five-level versions of EQ-5D compare? Health Qual Life Outcomes. 2015;13:171.CrossRef Feng Y, Devlin N, Herdman M. Assessing the health of the general population in England: how do the three- and five-level versions of EQ-5D compare? Health Qual Life Outcomes. 2015;13:171.CrossRef
5.
go back to reference Janssen MF, Pickard AS, Golicki D, Gudex C, Niewada M, Scalone L, et al. Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups: a multi-country study. Qual Life Res. 2013;22(7):1717–27.CrossRef Janssen MF, Pickard AS, Golicki D, Gudex C, Niewada M, Scalone L, et al. Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups: a multi-country study. Qual Life Res. 2013;22(7):1717–27.CrossRef
6.
go back to reference Kim TH, Jo MW, Lee SI, Kim SH, Chung SM. Psychometric properties of the EQ-5D-5L in the general population of South Korea. Qual Life Res. 2013;22(8):2245–53.CrossRef Kim TH, Jo MW, Lee SI, Kim SH, Chung SM. Psychometric properties of the EQ-5D-5L in the general population of South Korea. Qual Life Res. 2013;22(8):2245–53.CrossRef
7.
go back to reference Janssen MF, Bonsel GJ, Luo N. Is EQ-5D-5L better than EQ-5D-3L? A head-to-head comparison of descriptive systems and value sets from seven countries. PharmacoEconomics. 2018;36(6):675–97.CrossRef Janssen MF, Bonsel GJ, Luo N. Is EQ-5D-5L better than EQ-5D-3L? A head-to-head comparison of descriptive systems and value sets from seven countries. PharmacoEconomics. 2018;36(6):675–97.CrossRef
8.
go back to reference Abdin E, Subramaniam M, Vaingankar JA, Luo N, Chong SA. Measuring health-related quality of life among adults in Singapore: population norms for the EQ-5D. Qual Life Res. 2013;22(10):2983–91.CrossRef Abdin E, Subramaniam M, Vaingankar JA, Luo N, Chong SA. Measuring health-related quality of life among adults in Singapore: population norms for the EQ-5D. Qual Life Res. 2013;22(10):2983–91.CrossRef
9.
go back to reference Oppe M, Devlin NJ, van Hout B, Krabbe PFM, de Charro FA. Program of methodological research to arrive at the new international EQ-5D-5L valuation protocol. Value Health. 2014;17(4):445–53.CrossRef Oppe M, Devlin NJ, van Hout B, Krabbe PFM, de Charro FA. Program of methodological research to arrive at the new international EQ-5D-5L valuation protocol. Value Health. 2014;17(4):445–53.CrossRef
10.
go back to reference Jin XJ, Liu GG, Luo N, Li HC, Guan HJ. Xie F. is bad living better than good death? Impact of demographic and cultural factors on health state preference. Qual Life Res. 2016;25(4):979–86.CrossRef Jin XJ, Liu GG, Luo N, Li HC, Guan HJ. Xie F. is bad living better than good death? Impact of demographic and cultural factors on health state preference. Qual Life Res. 2016;25(4):979–86.CrossRef
11.
go back to reference Oppe M, Rand-Hendriksen K, Shah K, Ramos-Goni JM, Luo N. EuroQol protocols for time trade-off valuation of health outcomes. PharmacoEconomics. 2016;34(10):993–1004.CrossRef Oppe M, Rand-Hendriksen K, Shah K, Ramos-Goni JM, Luo N. EuroQol protocols for time trade-off valuation of health outcomes. PharmacoEconomics. 2016;34(10):993–1004.CrossRef
12.
go back to reference Pan CW, Sun HP, Wang XZ, Ma QH, Xu Y, Luo N, et al. The EQ-5D-5L index score is more discriminative than the EQ-5D-3L index score in diabetes patients. Qual Life Res. 2015;24(7):1767–74.CrossRef Pan CW, Sun HP, Wang XZ, Ma QH, Xu Y, Luo N, et al. The EQ-5D-5L index score is more discriminative than the EQ-5D-3L index score in diabetes patients. Qual Life Res. 2015;24(7):1767–74.CrossRef
13.
go back to reference Scalone L, Cortesi PA, Ciampichini R, Cesana G, Mantovani LG. Health Related Quality of Life norm data of the general population in Italy: results using the EQ-5D-3L and EQ-5D-5L instruments. Epidemiol Biostat Pu. 2015;12(3). https://doi.org/10.2427/11457. Scalone L, Cortesi PA, Ciampichini R, Cesana G, Mantovani LG. Health Related Quality of Life norm data of the general population in Italy: results using the EQ-5D-3L and EQ-5D-5L instruments. Epidemiol Biostat Pu. 2015;12(3). https://​doi.​org/​10.​2427/​11457.
14.
go back to reference McCaffrey N, Kaambwa B, Currow DC, Ratcliffe J. Health-related quality of life measured using the EQ-5D-5L: south Australian population norms. Health Qual Life. 2016;14:133.CrossRef McCaffrey N, Kaambwa B, Currow DC, Ratcliffe J. Health-related quality of life measured using the EQ-5D-5L: south Australian population norms. Health Qual Life. 2016;14:133.CrossRef
15.
go back to reference Hinz A, Kohlmann T, Stobel-Richter Y, Zenger M, Brahler E. The quality of life questionnaire EQ-5D-5L: psychometric properties and normative values for the general German population. Qual Life Res. 2014;23(2):443–7.CrossRef Hinz A, Kohlmann T, Stobel-Richter Y, Zenger M, Brahler E. The quality of life questionnaire EQ-5D-5L: psychometric properties and normative values for the general German population. Qual Life Res. 2014;23(2):443–7.CrossRef
16.
go back to reference Shiroiwa T, Fukuda T, Ikeda S, Igarashi A, Noto S, Saito S, et al. Japanese population norms for preference-based measures: EQ-5D-3L, EQ-5D-5L, and SF-6D. Qual Life Res. 2016;25(3):707–19.CrossRef Shiroiwa T, Fukuda T, Ikeda S, Igarashi A, Noto S, Saito S, et al. Japanese population norms for preference-based measures: EQ-5D-3L, EQ-5D-5L, and SF-6D. Qual Life Res. 2016;25(3):707–19.CrossRef
17.
go back to reference Garcia-Gordillo MA, Adsuar JC, Olivares PR. Normative values of EQ-5D-5L: in a Spanish representative population sample from Spanish health survey. 2011 Qual Life Res. 2016;25(5):1313–21.CrossRef Garcia-Gordillo MA, Adsuar JC, Olivares PR. Normative values of EQ-5D-5L: in a Spanish representative population sample from Spanish health survey. 2011 Qual Life Res. 2016;25(5):1313–21.CrossRef
18.
go back to reference Meng Q, Fang H, Liu X, Yuan B, Xu J. Consolidating the social health insurance schemes in China: towards an equitable and efficient health system. Lancet. 2015;386(10002):1484–92.CrossRef Meng Q, Fang H, Liu X, Yuan B, Xu J. Consolidating the social health insurance schemes in China: towards an equitable and efficient health system. Lancet. 2015;386(10002):1484–92.CrossRef
19.
go back to reference Fayers PM, Machin D. Quality of life: the assessment, analysis and interpretation of patient-reported outcomes. England: Wiley; 2007.CrossRef Fayers PM, Machin D. Quality of life: the assessment, analysis and interpretation of patient-reported outcomes. England: Wiley; 2007.CrossRef
20.
go back to reference Rand-Hendriksen K, Ramos-Goni JM, Augestad LA, Luo N. Less is more: cross-validation testing of simplified nonlinear regression model specifications for EQ-5D-5L health state values. Value Health. 2017;20(7):945–52.CrossRef Rand-Hendriksen K, Ramos-Goni JM, Augestad LA, Luo N. Less is more: cross-validation testing of simplified nonlinear regression model specifications for EQ-5D-5L health state values. Value Health. 2017;20(7):945–52.CrossRef
21.
go back to reference Sun S, Chen J, Johannesson M, Kind P, Xu L, Zhang Y, et al. Regional differences in health status in China: population health-related quality of life results from the National Health Services Survey 2008. Health Place. 2011;17(2):671–80.CrossRef Sun S, Chen J, Johannesson M, Kind P, Xu L, Zhang Y, et al. Regional differences in health status in China: population health-related quality of life results from the National Health Services Survey 2008. Health Place. 2011;17(2):671–80.CrossRef
22.
go back to reference Li H, Wei X, Ma A, Chung RY. Inequalities in health status among rural residents: EQ-5D findings from household survey China. Int J Equity Health. 2014;13:41.CrossRef Li H, Wei X, Ma A, Chung RY. Inequalities in health status among rural residents: EQ-5D findings from household survey China. Int J Equity Health. 2014;13:41.CrossRef
23.
go back to reference Zhang T, Shi WX, Huang ZQ, Gao D, Guo ZY, Liu JY, et al. Influence of culture, residential segregation and socioeconomic development on rural elderly health-related quality of life in Guangxi, China. Health Qual Life. 2016;14:98.CrossRef Zhang T, Shi WX, Huang ZQ, Gao D, Guo ZY, Liu JY, et al. Influence of culture, residential segregation and socioeconomic development on rural elderly health-related quality of life in Guangxi, China. Health Qual Life. 2016;14:98.CrossRef
24.
go back to reference Dong WL, Li YC, Wang ZQ, Jiang YY, Mao F, Qi L, et al. Self-rated health and health-related quality of life among Chinese residents, China, 2010. Health Qual Life. 2016;14:5.CrossRef Dong WL, Li YC, Wang ZQ, Jiang YY, Mao F, Qi L, et al. Self-rated health and health-related quality of life among Chinese residents, China, 2010. Health Qual Life. 2016;14:5.CrossRef
26.
go back to reference Sun S, Chen J, Johannesson M, Kind P, Xu L, Zhang Y, et al. Population health status in China: EQ-5D results, by age, sex and socio-economic status, from the National Health Services Survey 2008. Qual Life Res. 2011;20(3):309–20.CrossRef Sun S, Chen J, Johannesson M, Kind P, Xu L, Zhang Y, et al. Population health status in China: EQ-5D results, by age, sex and socio-economic status, from the National Health Services Survey 2008. Qual Life Res. 2011;20(3):309–20.CrossRef
27.
go back to reference Liu GG, Wu H, Li M, Gao C, Luo N. Chinese time trade-off values for EQ-5D health states. Value Health. 2014;17(5):597–604.CrossRef Liu GG, Wu H, Li M, Gao C, Luo N. Chinese time trade-off values for EQ-5D health states. Value Health. 2014;17(5):597–604.CrossRef
28.
go back to reference Visser M, Verbaan D, van Rooden S, Marinus J, van Hilten J. Stiggelbout a. a longitudinal evaluation of health-related quality of life of patients with Parkinson's disease. Value Health. 2009;12(2):392–6.CrossRef Visser M, Verbaan D, van Rooden S, Marinus J, van Hilten J. Stiggelbout a. a longitudinal evaluation of health-related quality of life of patients with Parkinson's disease. Value Health. 2009;12(2):392–6.CrossRef
29.
go back to reference Hajek A, Brettschneider C, Mallon T, Ernst A, Mamone S, Wiese B, et al. The impact of social engagement on health-related quality of life and depressive symptoms in old age - evidence from a multicenter prospective cohort study in Germany. Health Qual Life Outcomes. 2017;15(1):140.CrossRef Hajek A, Brettschneider C, Mallon T, Ernst A, Mamone S, Wiese B, et al. The impact of social engagement on health-related quality of life and depressive symptoms in old age - evidence from a multicenter prospective cohort study in Germany. Health Qual Life Outcomes. 2017;15(1):140.CrossRef
30.
go back to reference Alva M, Gray A, Mihaylova B, Clarke P. The effect of diabetes complications on health-related quality of life: the importance of longitudinal data to address patient heterogeneity. Health Econ. 2014;23(4):487–500.CrossRef Alva M, Gray A, Mihaylova B, Clarke P. The effect of diabetes complications on health-related quality of life: the importance of longitudinal data to address patient heterogeneity. Health Econ. 2014;23(4):487–500.CrossRef
Metadata
Title
EQ-5D-5L norms for the urban Chinese population in China
Authors
Zhihao Yang
Jan Busschbach
Gordon Liu
Nan Luo
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2018
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-018-1036-2

Other articles of this Issue 1/2018

Health and Quality of Life Outcomes 1/2018 Go to the issue