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Published in: Health and Quality of Life Outcomes 1/2015

Open Access 01-12-2015 | Research Article

Relationship between health-related quality of life, comorbidities and acute health care utilisation, in adults with chronic conditions

Authors: Anastasia F. Hutchinson, Marnie Graco, Tshepo Mokuedi Rasekaba, Sumit Parikh, David John Berlowitz, Wen Kwang Lim

Published in: Health and Quality of Life Outcomes | Issue 1/2015

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Abstract

Background

There is increased interest in developing multidisciplinary ambulatory care models of service delivery to manage patients with complex chronic diseases. These programs are expensive and given limited resources it is important that care is targeted effectively. One potential screening strategy is to identify individuals who report the greatest decrement in health related quality of life (HRQoL) and thus greater need. The aim of this study was to explore the relationship between HRQoL, comorbid conditions and acute health care utilisation.

Methods

A prospective, longitudinal cohort design was used to evaluate the impact of HRQoL on acute care utilisation rates over three-years of follow-up. Participants were enrolled in chronic disease management programs run by a metropolitan health service in Australia. Baseline data was collected from 2007–2009 and follow-up data until 2012. Administrative data was used to classify patients’ primary reasons for enrolment, number of comorbidities (Charlson Score) and presentations to acute care. At enrolment, HRQoL was measured using the Assessment of Quality of Life (AQoL) instrument, for analysis AQoL scores were dichotomised at two standard deviations below the population norm.

Results

There were 1999 participants (54 % male) with a mean age of 63 years (range 18–101), enrolled in the study. Participants’ primary health conditions at enrolment were: diabetes 915 (46 %), chronic respiratory disease 463 (23 %), cardiac disease 260 (13 %), peripheral vascular disease, and 181 (9 %) and aged care 180 (9 %). At 1-year multivariate logistic regression models demonstrated that AQOL utility score was not predictive of acute care presentations after adjusting for comorbidities. Over 3-years an AQoL utility score in the lowest quartile was predictive of both ED presentation (OR 1.58, 95 % CI, 1.16–2.13, p = 0.003) and admissions (OR 1.67, 95 % CI.1.21 to 2.30, p = 0.002) after adjusting for differences in age and comorbidities.

Conclusion

This study found that both HRQoL and comorbidities were predictive of subsequent acute care attendance over 3-years of follow-up. At 1-year, comorbidities was a better predictor of acute care representation than HRQoL. To maximise benefits, programs should initially focus on medical disease management, but subsequently switch to strategies that enhance health independence and raise HRQoL.
Literature
1.
go back to reference AIHW. Chronic diseases and associated risk factors in Australia. Canberra: Australian Institute of Health and Welfare; 2006; 2006. Report No.: Cat. no. PHE 81 Contract No.: Document Number. AIHW. Chronic diseases and associated risk factors in Australia. Canberra: Australian Institute of Health and Welfare; 2006; 2006. Report No.: Cat. no. PHE 81 Contract No.: Document Number.
5.
go back to reference Howell S, Coory M, Martin J, Duckett S. Using routine inpatient data to identify patients at risk of hospital readmission. BMC Health Serv Res. 2009;9:96.PubMedCentralPubMed Howell S, Coory M, Martin J, Duckett S. Using routine inpatient data to identify patients at risk of hospital readmission. BMC Health Serv Res. 2009;9:96.PubMedCentralPubMed
6.
go back to reference Grunier A, Dhallia IA, van Walraven C, Fischer HD, Camacho X, Rochon PA, et al. Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithm. Open Med. 2011;5(2):E104. Grunier A, Dhallia IA, van Walraven C, Fischer HD, Camacho X, Rochon PA, et al. Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithm. Open Med. 2011;5(2):E104.
7.
go back to reference Billings J, Dixon J, Mijanovich T, Wennberg D. Case finding for patients at risk of readmission to hospital: development of an alogithm to identify high risk patients. BMJ. 2006. doi:10.1136/bmj.38870.657917.AE. Billings J, Dixon J, Mijanovich T, Wennberg D. Case finding for patients at risk of readmission to hospital: development of an alogithm to identify high risk patients. BMJ. 2006. doi:10.1136/bmj.38870.657917.AE.
8.
go back to reference Soler JJ, Sanchez L, Roman P, Martinez MA, Perpina M. Risk factors of emergency care and admissions in COPD patients with high consumption of health respources. Respir Med. 2004;98(4):318–29.PubMed Soler JJ, Sanchez L, Roman P, Martinez MA, Perpina M. Risk factors of emergency care and admissions in COPD patients with high consumption of health respources. Respir Med. 2004;98(4):318–29.PubMed
9.
go back to reference Sprenkle MD, Niewoehner DE, Nelson DB, Kristin L, Nichol KL. The veterans short form 36 questionnaire is predictive of mortality and health-care utilization in a population of veterans with a self-reported diagnosis of asthma or COPD. Chest. 2004;126(1):81–9. doi:10.1378/chest.126.1.81.PubMed Sprenkle MD, Niewoehner DE, Nelson DB, Kristin L, Nichol KL. The veterans short form 36 questionnaire is predictive of mortality and health-care utilization in a population of veterans with a self-reported diagnosis of asthma or COPD. Chest. 2004;126(1):81–9. doi:10.1378/chest.126.1.81.PubMed
10.
go back to reference Fan VS, Curtis JR, Tu SP, McDonell MB, Fihn SD, Investigators ACQIP. Using quality of life to predict hospitalization and mortality in patients with obstructive lung diseases. Chest. 2002;122(2):429–36.PubMed Fan VS, Curtis JR, Tu SP, McDonell MB, Fihn SD, Investigators ACQIP. Using quality of life to predict hospitalization and mortality in patients with obstructive lung diseases. Chest. 2002;122(2):429–36.PubMed
11.
go back to reference Rodriguez-Artalejo F, Guallar-Castillion P, Rodriguez-Pascual C, Montoto C, Ortega Montes A, Nieto Garcia A, et al. Health-related quality of life as a predictor of hospital readmission an death among patients with heart failure. Arch Intern Med. 2005;165(11):1274–9.PubMed Rodriguez-Artalejo F, Guallar-Castillion P, Rodriguez-Pascual C, Montoto C, Ortega Montes A, Nieto Garcia A, et al. Health-related quality of life as a predictor of hospital readmission an death among patients with heart failure. Arch Intern Med. 2005;165(11):1274–9.PubMed
12.
go back to reference Bourbeau J, Julien M, Maltais F, Rouleau M, Beaupré A, Bégin R, et al. Reduction of hospital utilization in patients with chronic obstructive pulmonary disease: a disease-specific self-management intervention. Arch Intern Med. 2003;163(5):585–91.PubMed Bourbeau J, Julien M, Maltais F, Rouleau M, Beaupré A, Bégin R, et al. Reduction of hospital utilization in patients with chronic obstructive pulmonary disease: a disease-specific self-management intervention. Arch Intern Med. 2003;163(5):585–91.PubMed
13.
go back to reference Annema C, Luttik M-L, Jaarsma T. Reasons for readmission in heart failure: perspectives of patients, caregivers, cardiologists, and heart failure nurses. Heart Lung. 2009;38:427–34.PubMed Annema C, Luttik M-L, Jaarsma T. Reasons for readmission in heart failure: perspectives of patients, caregivers, cardiologists, and heart failure nurses. Heart Lung. 2009;38:427–34.PubMed
14.
go back to reference Krumholz HM, Chen Y-T, Wang Y, Vaccarino V, Radford MJ, Horwitz RI. Predictors of readmission among elderly survivors of admission with heart failure. Am Heart J. 2000;139(1):72–7.PubMed Krumholz HM, Chen Y-T, Wang Y, Vaccarino V, Radford MJ, Horwitz RI. Predictors of readmission among elderly survivors of admission with heart failure. Am Heart J. 2000;139(1):72–7.PubMed
15.
go back to reference Harvey P, Storer M, Berlowitz DJ, Jackson B, Hutchinson AF, Lim WK. Feasibility and impact of a post–discharge geriatric evaluation and management service for patients from residential care: the Residential Care Intervention Program in the Elderly (RECIPE). BMC Geriatr. 2014;14:48. doi:10.1186/1471-2318-14-48.PubMedCentralPubMed Harvey P, Storer M, Berlowitz DJ, Jackson B, Hutchinson AF, Lim WK. Feasibility and impact of a post–discharge geriatric evaluation and management service for patients from residential care: the Residential Care Intervention Program in the Elderly (RECIPE). BMC Geriatr. 2014;14:48. doi:10.1186/1471-2318-14-48.PubMedCentralPubMed
16.
go back to reference Berlowitz DJ, Graco M. The development of a streamlined, coordinated and sustainable evaluation methodology for a diverse chronic disease management program. Aust Health Rev. 2010;34(2):148–51.PubMed Berlowitz DJ, Graco M. The development of a streamlined, coordinated and sustainable evaluation methodology for a diverse chronic disease management program. Aust Health Rev. 2010;34(2):148–51.PubMed
17.
go back to reference Hutchinson AF, Rasekaba TM, Graco M, Berlowitz DJ, Hawthorne G, Lim WK. Relationship between health-related quality of life, and acute care re-admissions and survival in older adults with chronic illness. Health Qual Life Outcomes. 2013;11:136. doi:10.1186/1477-7525-11-136.PubMedCentralPubMed Hutchinson AF, Rasekaba TM, Graco M, Berlowitz DJ, Hawthorne G, Lim WK. Relationship between health-related quality of life, and acute care re-admissions and survival in older adults with chronic illness. Health Qual Life Outcomes. 2013;11:136. doi:10.1186/1477-7525-11-136.PubMedCentralPubMed
18.
go back to reference Hawthorne G, Richardson J, Osborne R. The Assessment of Quality of Life (AQoL) instrument: a psychometric measure of health-related quality of life. Qual Life Res. 1999;8(3):209–24.PubMed Hawthorne G, Richardson J, Osborne R. The Assessment of Quality of Life (AQoL) instrument: a psychometric measure of health-related quality of life. Qual Life Res. 1999;8(3):209–24.PubMed
19.
go back to reference Osborne RH, Hawthorne G, Lew EA, Gray LC. Quality of Life assessment in the community-dwelling elderly: validation of the Assessment of Quality of Life (AQoL) instrument and comparison with the SF-36. J Clin Epidemiol. 2003;56(2):138–47.PubMed Osborne RH, Hawthorne G, Lew EA, Gray LC. Quality of Life assessment in the community-dwelling elderly: validation of the Assessment of Quality of Life (AQoL) instrument and comparison with the SF-36. J Clin Epidemiol. 2003;56(2):138–47.PubMed
20.
go back to reference Hawthorne G, Osborne R. Population norms and meaningful differences for the Assessment of Quality of Life (AQoL) measure. Aust N Z J Public Health. 2005;29(2):136–42.PubMed Hawthorne G, Osborne R. Population norms and meaningful differences for the Assessment of Quality of Life (AQoL) measure. Aust N Z J Public Health. 2005;29(2):136–42.PubMed
21.
go back to reference Hawthorne G, Korn S, Richardson JR. Population norms for the AQoL derived from the 2007 Australian National Survey of Mental Health and Wellbeing. Aust N Z J Public Health. In press; Accepted 18 October. Hawthorne G, Korn S, Richardson JR. Population norms for the AQoL derived from the 2007 Australian National Survey of Mental Health and Wellbeing. Aust N Z J Public Health. In press; Accepted 18 October.
23.
go back to reference Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi JC, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005;43(11):1130–9.PubMed Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi JC, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005;43(11):1130–9.PubMed
24.
go back to reference Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.PubMed Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.PubMed
25.
go back to reference Welch BL. The generalization of “Student’s” problem when several different population variances are involved”. Biometrika. 1947;34(1–2):28–35.PubMed Welch BL. The generalization of “Student’s” problem when several different population variances are involved”. Biometrika. 1947;34(1–2):28–35.PubMed
27.
29.
go back to reference Banham D, Hawthorne G, Goldney R, Ratcliffe J. Health-related qulaity of life (HRQoL) changes in South Australia: comparsion of burden of disease morbidity and survey-based health itility estimates. Health Qual Life Ouctomes. 2014;12:113. doi:10.1186/s12955-014-0113-4. Banham D, Hawthorne G, Goldney R, Ratcliffe J. Health-related qulaity of life (HRQoL) changes in South Australia: comparsion of burden of disease morbidity and survey-based health itility estimates. Health Qual Life Ouctomes. 2014;12:113. doi:10.​1186/​s12955-014-0113-4.
30.
go back to reference Bilotta C, Bowling A, Nicolini P, Case A, Pina G, Rossi SV, et al. Older people’s Quality of Life (OPQOL) scores and adverse health outcomes at a one-year follow-ip A prospectove cohort study on older outpatients in the community in Italy. Health Qual Life Outcomes. 2011;9:72. doi:10.1186/1477-7525-9-72.PubMedCentralPubMed Bilotta C, Bowling A, Nicolini P, Case A, Pina G, Rossi SV, et al. Older people’s Quality of Life (OPQOL) scores and adverse health outcomes at a one-year follow-ip A prospectove cohort study on older outpatients in the community in Italy. Health Qual Life Outcomes. 2011;9:72. doi:10.​1186/​1477-7525-9-72.PubMedCentralPubMed
31.
go back to reference Cavrini, G., Broccoli S, Puccini A, Zoli B. EQ-5D as a predictor of mortality and hospitalization in elderly people. Qual Life Res. 2012;21(2):269-80. doi:10.1007/s11136-011-9937-0. Epub 2011 Jun 9. Cavrini, G., Broccoli S, Puccini A, Zoli B. EQ-5D as a predictor of mortality and hospitalization in elderly people. Qual Life Res. 2012;21(2):269-80. doi:10.1007/s11136-011-9937-0. Epub 2011 Jun 9.
32.
go back to reference Shim EU, Ma SH, Hong SH, Lee YS, Paik WY, Seo DS, et al. Correlation between frailty level and adverse health-related outcomes of community-dwelling elderly, one year retrospective study. Korean J Fam Med. 2011;32(4):249–56.PubMedCentralPubMed Shim EU, Ma SH, Hong SH, Lee YS, Paik WY, Seo DS, et al. Correlation between frailty level and adverse health-related outcomes of community-dwelling elderly, one year retrospective study. Korean J Fam Med. 2011;32(4):249–56.PubMedCentralPubMed
33.
go back to reference Bilotta C, Bowling A, Case A, Nicolini P, Mauri S, Castelli M, et al. Dimensions and correlates of quality of life according to frailty status: a cross-sectional study on community-dwelling older adults referred to an outpatient geriatric service in Italy. Health Qual Life Outcomes. 2010;8:56.PubMedCentralPubMed Bilotta C, Bowling A, Case A, Nicolini P, Mauri S, Castelli M, et al. Dimensions and correlates of quality of life according to frailty status: a cross-sectional study on community-dwelling older adults referred to an outpatient geriatric service in Italy. Health Qual Life Outcomes. 2010;8:56.PubMedCentralPubMed
34.
go back to reference Bowling A, Grundy E. Differentials in mortality up to 20 years after baseline interview among older people in East London and Essex. Age Ageing. 2009;38:51–5.PubMed Bowling A, Grundy E. Differentials in mortality up to 20 years after baseline interview among older people in East London and Essex. Age Ageing. 2009;38:51–5.PubMed
35.
go back to reference Perkins AJ, Kroenke K, Unutzer J, Katon W, Williams JW, Hope C, et al. Common comorbidity scales were similar in their ability to predict health care costs and mortality. J Clin Epidemiol. 2004;57:1040–8. doi:10.1016/j.jclinepi.2004.03.002.PubMed Perkins AJ, Kroenke K, Unutzer J, Katon W, Williams JW, Hope C, et al. Common comorbidity scales were similar in their ability to predict health care costs and mortality. J Clin Epidemiol. 2004;57:1040–8. doi:10.1016/j.jclinepi.2004.03.002.PubMed
36.
go back to reference Agborsangaya CB, Lau D, Lahtinen M, Cooke T, Johnson JA. Multimorbidity prevalence and patterns across socioeconomic determinats: a cross-sectional survey. BMC Public Health. 2012;12:201.CrossRefPubMedCentralPubMed Agborsangaya CB, Lau D, Lahtinen M, Cooke T, Johnson JA. Multimorbidity prevalence and patterns across socioeconomic determinats: a cross-sectional survey. BMC Public Health. 2012;12:201.CrossRefPubMedCentralPubMed
38.
go back to reference Ng T-P, Niti M, Tan W-T, Cao Z, Ong K-C, Eng P. Depressive symptoms and chronic obstructive pulmonary disease. Effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med. 2007;167(1):60–7. doi:10.1001/archinte.167.1.60.PubMed Ng T-P, Niti M, Tan W-T, Cao Z, Ong K-C, Eng P. Depressive symptoms and chronic obstructive pulmonary disease. Effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med. 2007;167(1):60–7. doi:10.1001/archinte.167.1.60.PubMed
39.
go back to reference Simon GE, Katon WJ, Lin EHB, Ludman E, von Korff M, Ciechanowski P, et al. Diabetes complications and depression as predictors of healthcare costs. General Hospital Psychiatry, 2005, 344–351. doi:10.1016j.genhosppsych.2005.04.008. Simon GE, Katon WJ, Lin EHB, Ludman E, von Korff M, Ciechanowski P, et al. Diabetes complications and depression as predictors of healthcare costs. General Hospital Psychiatry, 2005, 344–351. doi:10.1016j.genhosppsych.2005.04.008.
40.
go back to reference Walker AE. Multiple chronic diseases and quality of life: patterns emerging from a large national sample, Australia. Chronic Illn. 2007;3:202–18.PubMed Walker AE. Multiple chronic diseases and quality of life: patterns emerging from a large national sample, Australia. Chronic Illn. 2007;3:202–18.PubMed
Metadata
Title
Relationship between health-related quality of life, comorbidities and acute health care utilisation, in adults with chronic conditions
Authors
Anastasia F. Hutchinson
Marnie Graco
Tshepo Mokuedi Rasekaba
Sumit Parikh
David John Berlowitz
Wen Kwang Lim
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2015
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-015-0260-2

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