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Published in: Cardiovascular Ultrasound 1/2015

Open Access 01-12-2015 | Research

Ultrasonographic caval indices do not significantly contribute to predicting fluid responsiveness immediately after coronary artery bypass grafting when compared to passive leg raising

Authors: Dorota Sobczyk, Krzysztof Nycz, Pawel Andruszkiewicz, Karol Wierzbicki, Maciej Stapor

Published in: Cardiovascular Ultrasound | Issue 1/2015

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Abstract

Background

Appropriate fluid management is one of the most important elements of early goal-directed therapy after cardiothoracic surgery. Reliable determination of fluid responsivenss remains the fundamental issue in volume therapy.
The purpose of the study was to assess the usefulness of dynamic IVC-derived parameters (collapsibility index, distensibility index) in comparison to passive leg raising, in postoperative fluid management in mechanically ventilated patients with left ventricular ejection fraction ≥ 30 %, immediately after elective coronary artery bypass grafting.

Methods

Prospective observational case series study including 35 patients with LVEF ≥ 30 %, undergoingelective coronary artery bypass grafting was conducted. Transthoracic echocardiography, passive leg raising and intravenous administration of saline were performed in all study subjects. Dynamic parameters derived from ultrasonographic assessment of the IVC diameter (collapsibility index–CI and distensibility index–DI), cardiac output

Results

There were 24 (68.57 %) responders in the study population. There were no statistical differences between the groups in relation to: clinical parameters, pre- and postoperative LVEF, fluid balance and CVP. Change in cardiac output after passive leg raising correlated significantly with that after the volume expansion (p=0.000, r=0.822). Dynamic IVC derivatives were slightly higher in fluid responders, however this trend did not reach statistical significance. None of the caval indices correlated with fluid responsiveness.

Conclusion

Dynamic IVC-derived parameters do not predict fluid responsiveness in mechanically ventilated patients with preserved ejection fraction immediately after elective coronary artery bypass grafting. Passive leg raising is not inferior to volume expansion in differentiating between fluid responders and nonresponders. Immediate fluid challenge after CABG is safe and well tolerated.
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Literature
1.
go back to reference Cecconi M, Corredor C, Arulkumaran N, Abuella G, Ball J, Grounds RM, Hamilton M, Rhodes A. Clinical review: goal-directed therapy - What is the evidence in surgical patients? The effect on different risk groups. Crit Care. 2013;17:209.CrossRefPubMedPubMedCentral Cecconi M, Corredor C, Arulkumaran N, Abuella G, Ball J, Grounds RM, Hamilton M, Rhodes A. Clinical review: goal-directed therapy - What is the evidence in surgical patients? The effect on different risk groups. Crit Care. 2013;17:209.CrossRefPubMedPubMedCentral
2.
go back to reference Brandstrup B, Tonnesen H, Beier-Holgersen R, et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg. 2003;238:641–8.CrossRefPubMedPubMedCentral Brandstrup B, Tonnesen H, Beier-Holgersen R, et al. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg. 2003;238:641–8.CrossRefPubMedPubMedCentral
3.
go back to reference Garcia X, Gruartmoner G, Mesquida J. Fluid optimization strategies in critical care patients. Crit Care. 2013;1(1):4–8. Garcia X, Gruartmoner G, Mesquida J. Fluid optimization strategies in critical care patients. Crit Care. 2013;1(1):4–8.
5.
go back to reference Morin J-F, Mistry B, Langlois Y, et al. Fluid overload after coronary artery bypass grafting surgery increases the incidence of post-operative complications. World J Cardiovasc Surg. 2011;1:18–23.CrossRef Morin J-F, Mistry B, Langlois Y, et al. Fluid overload after coronary artery bypass grafting surgery increases the incidence of post-operative complications. World J Cardiovasc Surg. 2011;1:18–23.CrossRef
6.
go back to reference Bellomo R, Raman J, Ronco C. Intensive care unit management of the critically ill patient with fluid overload after open-heart surgery. Cardiology. 2011;96(3–4):169–76. Bellomo R, Raman J, Ronco C. Intensive care unit management of the critically ill patient with fluid overload after open-heart surgery. Cardiology. 2011;96(3–4):169–76.
7.
go back to reference Andre AS, DelRossi AL. Hemodynamic management of patients in the first 24 hours after cardiac surgery. Crit Care Med. 2005;33(9):2082–93.CrossRef Andre AS, DelRossi AL. Hemodynamic management of patients in the first 24 hours after cardiac surgery. Crit Care Med. 2005;33(9):2082–93.CrossRef
10.
go back to reference Feissel M, Michard F, Faller JP, et al. The respiratory variation in inferior vena cava diameter as a guide to fluid therapy. Intensive Care Med. 2004;30:1834–7.CrossRefPubMed Feissel M, Michard F, Faller JP, et al. The respiratory variation in inferior vena cava diameter as a guide to fluid therapy. Intensive Care Med. 2004;30:1834–7.CrossRefPubMed
11.
go back to reference Cheriex EC, Leunissen KM, Janssen JH, et al. Echography of the inferior vena cava is a simple and reliable tool for estimation of dry weight in haemodialysis patients. Nephrol Dial Transplant. 1989;4(6):563–8.PubMed Cheriex EC, Leunissen KM, Janssen JH, et al. Echography of the inferior vena cava is a simple and reliable tool for estimation of dry weight in haemodialysis patients. Nephrol Dial Transplant. 1989;4(6):563–8.PubMed
12.
go back to reference Guiotto G, Masarone M, Paladino F, et al. Inferior vena cava collapsibility to guide fluid removal in slow continuous ultrafiltration: a pilot study. Intensive Care Med. 2010;36(4):692–6.CrossRefPubMed Guiotto G, Masarone M, Paladino F, et al. Inferior vena cava collapsibility to guide fluid removal in slow continuous ultrafiltration: a pilot study. Intensive Care Med. 2010;36(4):692–6.CrossRefPubMed
13.
go back to reference Barbier C, Loubieres Y, Schmit C, et al. Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients. Intensive Care Med. 2004;30(9):1740–6.PubMed Barbier C, Loubieres Y, Schmit C, et al. Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients. Intensive Care Med. 2004;30(9):1740–6.PubMed
14.
go back to reference Kusaba T, Yamaguchi K, Oda H. Echography of the inferior vena cava for estimating fluid removal from patients undergoing hemodialysis. Jpn J Nephrol. 1994;36(8):914–20. Kusaba T, Yamaguchi K, Oda H. Echography of the inferior vena cava for estimating fluid removal from patients undergoing hemodialysis. Jpn J Nephrol. 1994;36(8):914–20.
15.
go back to reference Moretti R, Pizzi B. Inferior vena cava distensibility index as a predictor of fluid responsiveness in patients with subarachnoid hemorrhage. Neurocrit Care. 2010;13(1):3–9.CrossRefPubMed Moretti R, Pizzi B. Inferior vena cava distensibility index as a predictor of fluid responsiveness in patients with subarachnoid hemorrhage. Neurocrit Care. 2010;13(1):3–9.CrossRefPubMed
16.
go back to reference Sobczyk D, Nycz K, Andruszkiewicz P. Bedside ultrasonographic measurement of inferior vena cava fails to predict fluid responsiveness in the first 6 hours after cardiac surgery: a prospective case series observational study. J Cardiothorac Vasc Anesth. 2014. doi:10.1053/j.jvca.2014.08.015 [Epub ahead of print].PubMed Sobczyk D, Nycz K, Andruszkiewicz P. Bedside ultrasonographic measurement of inferior vena cava fails to predict fluid responsiveness in the first 6 hours after cardiac surgery: a prospective case series observational study. J Cardiothorac Vasc Anesth. 2014. doi:10.​1053/​j.​jvca.​2014.​08.​015 [Epub ahead of print].PubMed
17.
go back to reference Lewis JF, Kuo LC, Nelson JG, et al. Pulsed Doppler echocardiographic determination of stroke volume and cardiac output: clinical validation of two new methods using the apical window. Circulation. 1984;70(3):425–31.CrossRefPubMed Lewis JF, Kuo LC, Nelson JG, et al. Pulsed Doppler echocardiographic determination of stroke volume and cardiac output: clinical validation of two new methods using the apical window. Circulation. 1984;70(3):425–31.CrossRefPubMed
19.
go back to reference Corl K, Napoli AM, Gardiner F. Bedside sonographic measurement of the inferior vena cava caval index is a poor predictor of fluid responsiveness in emergency department patients. Emerg Med Australas. 2012;24:534–9.CrossRefPubMed Corl K, Napoli AM, Gardiner F. Bedside sonographic measurement of the inferior vena cava caval index is a poor predictor of fluid responsiveness in emergency department patients. Emerg Med Australas. 2012;24:534–9.CrossRefPubMed
20.
go back to reference Juhl-Olsen P, Vistisen ST, Christiansen LK, et al. Ultrasound of the inferior vena cava dose not predict hemodynamic response to early hemorrhage. J Emerg Med. 2013;45(4):592–7.CrossRefPubMed Juhl-Olsen P, Vistisen ST, Christiansen LK, et al. Ultrasound of the inferior vena cava dose not predict hemodynamic response to early hemorrhage. J Emerg Med. 2013;45(4):592–7.CrossRefPubMed
21.
go back to reference Godje O, Peyerl M, Seebauer T, et al. Central venous pressure, pulmonary capillary wedge pressure and intrathoracic blood volumes as preload indicators in cardiac surgery patients. Eur J Cardiothorac Surg. 1998;13(5):533–9.CrossRefPubMed Godje O, Peyerl M, Seebauer T, et al. Central venous pressure, pulmonary capillary wedge pressure and intrathoracic blood volumes as preload indicators in cardiac surgery patients. Eur J Cardiothorac Surg. 1998;13(5):533–9.CrossRefPubMed
22.
go back to reference Michard F, Boussat S, Chemla D, et al. Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Respir Crit Care Med. 2000;162(1):134–8.CrossRefPubMed Michard F, Boussat S, Chemla D, et al. Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Respir Crit Care Med. 2000;162(1):134–8.CrossRefPubMed
23.
go back to reference Michard F, Chemla D, Richard C, Wysocki M, Pinsky MR, Lecarpentier Y, Teboul JL. Clinical use of respiratory changes in arterial pulse pressure to monitor the hemodynamic effects of PEEP. Am J Respir Crit Care Med. 1999;159(3):935–9.CrossRefPubMed Michard F, Chemla D, Richard C, Wysocki M, Pinsky MR, Lecarpentier Y, Teboul JL. Clinical use of respiratory changes in arterial pulse pressure to monitor the hemodynamic effects of PEEP. Am J Respir Crit Care Med. 1999;159(3):935–9.CrossRefPubMed
24.
go back to reference Maizel J, Airapetian N, Lorne E, Tribouilloy C, Massy Z, Slama M. Diagnosis of hypovolemia by using passive leg raising. Intensive Care Med. 2007;33(7):1133–8.CrossRefPubMed Maizel J, Airapetian N, Lorne E, Tribouilloy C, Massy Z, Slama M. Diagnosis of hypovolemia by using passive leg raising. Intensive Care Med. 2007;33(7):1133–8.CrossRefPubMed
26.
go back to reference Monnet X, Rienzo M, Osman D, Anguel N, Richard C, Pinsky MR, Teboul J-L. Passive leg raising predicts fluid responsiveness in the critically ill. Crit Care Med. 2006;34(5):1402–7.CrossRefPubMed Monnet X, Rienzo M, Osman D, Anguel N, Richard C, Pinsky MR, Teboul J-L. Passive leg raising predicts fluid responsiveness in the critically ill. Crit Care Med. 2006;34(5):1402–7.CrossRefPubMed
27.
go back to reference Lamia B, Ochagavia A, Monnet X, Chemla D, Richard C, Teboul JL. Echocardiographic prediction of volume responsiveness in critically ill patients with spontaneously breathing activity. Intensive Care Med. 2007;33(7):1125–32.CrossRefPubMed Lamia B, Ochagavia A, Monnet X, Chemla D, Richard C, Teboul JL. Echocardiographic prediction of volume responsiveness in critically ill patients with spontaneously breathing activity. Intensive Care Med. 2007;33(7):1125–32.CrossRefPubMed
28.
go back to reference Monnet X, Marik P, Teboul J-L. Passive leg raising for predicting fluid responsiveness: a systematic review and meta-analysis. Intensive Care Med. 2016. doi:10.1007/s00134-015-4134-1. Monnet X, Marik P, Teboul J-L. Passive leg raising for predicting fluid responsiveness: a systematic review and meta-analysis. Intensive Care Med. 2016. doi:10.​1007/​s00134-015-4134-1.
29.
go back to reference Thiele RH, Bartels K, Gan TJ. Cardiac output monitoring: a contemporary assessment and review. Crit Care Med. 2015;43(1):177–85.CrossRefPubMed Thiele RH, Bartels K, Gan TJ. Cardiac output monitoring: a contemporary assessment and review. Crit Care Med. 2015;43(1):177–85.CrossRefPubMed
30.
go back to reference Sandham JD, Hull RD, Brant RF, Knox L, Pineo GF, Doig CJ, et al. Canadian Clinical Trials Group A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med. 2003;348(1):5–14.CrossRefPubMed Sandham JD, Hull RD, Brant RF, Knox L, Pineo GF, Doig CJ, et al. Canadian Clinical Trials Group A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med. 2003;348(1):5–14.CrossRefPubMed
31.
go back to reference Richard C, Warszawski J, Anguel N, Deye N, Combes A, Barnoud D, et al. French Pulmonary Artery Catheter Study Group. Early use of the pulmonary artery catheter and outcomes in patients with shock and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2003;290(20):2713–20.CrossRefPubMed Richard C, Warszawski J, Anguel N, Deye N, Combes A, Barnoud D, et al. French Pulmonary Artery Catheter Study Group. Early use of the pulmonary artery catheter and outcomes in patients with shock and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2003;290(20):2713–20.CrossRefPubMed
32.
go back to reference Harvey S, Harrison DA, Singer M, Ashcroft J, Jones CM, Elbourne D, et al. PAC-Man study collaboration. Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomized controlled trial. Lancet. 2005;366(9484):472–7.CrossRefPubMed Harvey S, Harrison DA, Singer M, Ashcroft J, Jones CM, Elbourne D, et al. PAC-Man study collaboration. Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomized controlled trial. Lancet. 2005;366(9484):472–7.CrossRefPubMed
Metadata
Title
Ultrasonographic caval indices do not significantly contribute to predicting fluid responsiveness immediately after coronary artery bypass grafting when compared to passive leg raising
Authors
Dorota Sobczyk
Krzysztof Nycz
Pawel Andruszkiewicz
Karol Wierzbicki
Maciej Stapor
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Cardiovascular Ultrasound / Issue 1/2015
Electronic ISSN: 1476-7120
DOI
https://doi.org/10.1186/s12947-016-0065-4

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Reviewer acknowledgement

Reviewer acknowledgment 2015