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International Journal for Equity in Health
Published in: International Journal for Equity in Health 1/2017

Open Access 01-12-2017 | Research

The association of early life socioeconomic conditions with prediabetes and type 2 diabetes: results from the Maastricht study

Authors: Ivonne P. M. Derks, Annemarie Koster, Miranda T. Schram, Coen D. A. Stehouwer, Pieter C. Dagnelie, Danielle A. I. Groffen, Hans Bosma

Published in: International Journal for Equity in Health | Issue 1/2017

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Abstract

Background

Using cross-sectional data from The Maastricht Study, we examined the association of socioeconomic conditions in early life with prediabetes and T2DM in adulthood. We also examined potential mediating pathways via both adulthood socioeconomic conditions and adult BMI and health behaviours.

Methods

Of the 3263 participants (aged 40–75 years), 493 had prediabetes and 906 were diagnosed with T2DM. By using logistic regression analyses, the associations and possible mediating pathways were examined.

Results

Participants with low early life socioeconomic conditions had a 1.56 times higher odds of prediabetes (95% confidence interval (CI) = 1.21-2.02) and a 1.61 times higher odds of T2DM (95% CI = 1.31-1.99). The relation between low early life socioeconomic conditions and prediabetes was independent of current socioeconomic conditions (OR = 1.38, 95% CI = 1.05-1.80), whereas the relation with T2DM was not independent of current socioeconomic conditions (OR = 1.10, 95% CI = 0.87-1.37). BMI party mediated the association between early life socioeconomic conditions and prediabetes.

Conclusions

Socioeconomic inequalities starting in early life were associated with diabetes-related outcomes in adulthood and suggest the usefulness of early life interventions aimed at tackling these inequalities.
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Metadata
Title
The association of early life socioeconomic conditions with prediabetes and type 2 diabetes: results from the Maastricht study
Authors
Ivonne P. M. Derks
Annemarie Koster
Miranda T. Schram
Coen D. A. Stehouwer
Pieter C. Dagnelie
Danielle A. I. Groffen
Hans Bosma
Publication date
01-12-2017
Publisher
BioMed Central
Published in
International Journal for Equity in Health / Issue 1/2017
Electronic ISSN: 1475-9276
DOI
https://doi.org/10.1186/s12939-017-0553-7

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