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Published in: Malaria Journal 1/2017

Open Access 01-12-2017 | Research

Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin

Authors: John Bradley, Aurore Ogouyèmi-Hounto, Sylvie Cornélie, Jacob Fassinou, Yolande Sissinto Savi de Tove, Adicath Adéola Adéothy, Filémon T. Tokponnon, Patrick Makoutode, Alioun Adechoubou, Thibaut Legba, Telesphore Houansou, Dorothée Kinde-Gazard, Martin C. Akogbeto, Achille Massougbodji, Tessa Bellamy Knox, Martin Donnelly, Immo Kleinschmidt

Published in: Malaria Journal | Issue 1/2017

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Abstract

Background

Malaria control is heavily reliant on insecticides, especially pyrethroids. Resistance of mosquitoes to insecticides may threaten the effectiveness of insecticide-based vector control and lead to a resurgence of malaria in Africa.

Methods

In 21 villages in Southern Benin with high levels of insecticide resistance, the resistance status of local vectors was measured at the same time as the prevalence of malaria infection in resident children.

Results

Children who used LLINs had lower levels of malaria infection [odds ratio = 0.76 (95% CI 0.59, 0.98, p = 0.033)]. There was no evidence that the effectiveness of nets was different in high and low resistance locations (p = 0.513). There was no association between village level resistance and village level malaria prevalence (p = 0.999).

Conclusions

LLINs continue to offer individual protection against malaria infection in an area of high resistance. Insecticide resistance is not a reason to stop efforts to increase coverage of LLINs in Africa.
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Metadata
Title
Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin
Authors
John Bradley
Aurore Ogouyèmi-Hounto
Sylvie Cornélie
Jacob Fassinou
Yolande Sissinto Savi de Tove
Adicath Adéola Adéothy
Filémon T. Tokponnon
Patrick Makoutode
Alioun Adechoubou
Thibaut Legba
Telesphore Houansou
Dorothée Kinde-Gazard
Martin C. Akogbeto
Achille Massougbodji
Tessa Bellamy Knox
Martin Donnelly
Immo Kleinschmidt
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2017
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-017-1873-1

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