Skip to main content
Top
Published in: Malaria Journal 1/2015

Open Access 01-12-2015 | Research

Cost effectiveness and resource allocation of Plasmodium falciparum malaria control in Myanmar: a modelling analysis of bed nets and community health workers

Authors: Tom L. Drake, Shwe Sin Kyaw, Myat Phone Kyaw, Frank M. Smithuis, Nicholas P. J. Day, Lisa J. White, Yoel Lubell

Published in: Malaria Journal | Issue 1/2015

Login to get access

Abstract

Background

Funding for malaria control and elimination in Myanmar has increased markedly in recent years. While there are various malaria control tools currently available, two interventions receive the majority of malaria control funding in Myanmar: (1) insecticide-treated bed nets and (2) early diagnosis and treatment through malaria community health workers. This study aims to provide practical recommendations on how to maximize impact from investment in these interventions.

Methods

A simple decision tree is used to model intervention costs and effects in terms of years of life lost. The evaluation is from the perspective of the service provider and costs and effects are calculated in line with standard methodology. Sensitivity and scenario analysis are undertaken to identify key drivers of cost effectiveness. Standard cost effectiveness analysis is then extended via a spatially explicit resource allocation model.

Findings

Community health workers have the potential for high impact on malaria, particularly where there are few alternatives to access malaria treatment, but are relatively costly. Insecticide-treated bed nets are comparatively inexpensive and modestly effective in Myanmar, representing a low risk but modest return intervention. Unlike some healthcare interventions, bed nets and community health workers are not mutually exclusive nor are they necessarily at their most efficient when universally applied. Modelled resource allocation scenarios highlight that in this case there is no “one size fits all” cost effectiveness result. Health gains will be maximized by effective targeting of both interventions.
Appendix
Available only for authorised users
Literature
1.
go back to reference Tun KM, Imwong M, Lwin KM, Win AA, Hlaing TM, Hlaing T et al. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker. Lancet Infect Dis. 2015;15:415–21.PubMedCentralCrossRefPubMed Tun KM, Imwong M, Lwin KM, Win AA, Hlaing TM, Hlaing T et al. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker. Lancet Infect Dis. 2015;15:415–21.PubMedCentralCrossRefPubMed
2.
go back to reference Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411–23.PubMedCentralCrossRefPubMed Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411–23.PubMedCentralCrossRefPubMed
3.
go back to reference Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, et al. Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. J Infect Dis. 2014. Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, et al. Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. J Infect Dis. 2014.
4.
go back to reference WHO. World Malaria Report. Geneva: World Health Organization; 2013. WHO. World Malaria Report. Geneva: World Health Organization; 2013.
5.
go back to reference Smithuis FM, Kyaw MK, Phe UO, van der Broek I, Katterman N, Rogers C, et al. The effect of insecticide-treated bed nets on the incidence and prevalence of malaria in children in an area of unstable seasonal transmission in western Myanmar. Malar J. 2013;12:363.PubMedCentralCrossRefPubMed Smithuis FM, Kyaw MK, Phe UO, van der Broek I, Katterman N, Rogers C, et al. The effect of insecticide-treated bed nets on the incidence and prevalence of malaria in children in an area of unstable seasonal transmission in western Myanmar. Malar J. 2013;12:363.PubMedCentralCrossRefPubMed
6.
go back to reference Kongmee M, Achee NL, Lerdthusnee K, Bangs MJ, Chowpongpang S, Prabaripai A, et al. Seasonal abundance and distribution of Anopheles larvae in a riparian malaria endemic area of western Thailand. Southeast Asian J Trop Med Public Health. 2012;43:601–13.PubMed Kongmee M, Achee NL, Lerdthusnee K, Bangs MJ, Chowpongpang S, Prabaripai A, et al. Seasonal abundance and distribution of Anopheles larvae in a riparian malaria endemic area of western Thailand. Southeast Asian J Trop Med Public Health. 2012;43:601–13.PubMed
7.
go back to reference Shi W, Zhou X, Zhang Y, Zhou X, Hu L, Wang X, et al. An investigation on malaria vectors in western part of China–Myanmar border. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2011;29:134–7.PubMed Shi W, Zhou X, Zhang Y, Zhou X, Hu L, Wang X, et al. An investigation on malaria vectors in western part of China–Myanmar border. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2011;29:134–7.PubMed
8.
9.
go back to reference Briet OJ, Chitnis N. Effects of changing mosquito host searching behaviour on the cost effectiveness of a mass distribution of long-lasting, insecticidal nets: a modelling study. Malar J. 2013;12:215.PubMedCentralCrossRefPubMed Briet OJ, Chitnis N. Effects of changing mosquito host searching behaviour on the cost effectiveness of a mass distribution of long-lasting, insecticidal nets: a modelling study. Malar J. 2013;12:215.PubMedCentralCrossRefPubMed
10.
go back to reference Yeung S, Damme WV, Socheat D, White NJ, Mills A. Cost of increasing access to artemisinin combination therapy: the Cambodian experience. Malar J. 2008;7:84.PubMedCentralCrossRefPubMed Yeung S, Damme WV, Socheat D, White NJ, Mills A. Cost of increasing access to artemisinin combination therapy: the Cambodian experience. Malar J. 2008;7:84.PubMedCentralCrossRefPubMed
11.
go back to reference Onwujekwe O, Uzochukwu B, Ojukwu J, Dike N, Shu E. Feasibility of a community health worker strategy for providing near and appropriate treatment of malaria in southeast Nigeria: an analysis of activities, costs and outcomes. Acta Trop. 2007;101:95–105.CrossRefPubMed Onwujekwe O, Uzochukwu B, Ojukwu J, Dike N, Shu E. Feasibility of a community health worker strategy for providing near and appropriate treatment of malaria in southeast Nigeria: an analysis of activities, costs and outcomes. Acta Trop. 2007;101:95–105.CrossRefPubMed
12.
go back to reference McCord GC, Liu A, Singh P: Deployment of community health workers across rural sub-Saharan Africa: financial considerations and operational assumptions. Bull World Health Organ. 2013; 91:244–53B. McCord GC, Liu A, Singh P: Deployment of community health workers across rural sub-Saharan Africa: financial considerations and operational assumptions. Bull World Health Organ. 2013; 91:244–53B.
13.
go back to reference Drummond MF, Sculpher MJ, Torrance GW. Methods for the economic evaluation of health care programs. Oxford: Oxford University Press; 2005. Drummond MF, Sculpher MJ, Torrance GW. Methods for the economic evaluation of health care programs. Oxford: Oxford University Press; 2005.
14.
go back to reference Lubell Y, Staedke SG, Greenwood BM, Kamya MR, Molyneux M, Newton PN, et al. Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey. PLoS One. 2011;6:e17439.PubMedCentralCrossRefPubMed Lubell Y, Staedke SG, Greenwood BM, Kamya MR, Molyneux M, Newton PN, et al. Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey. PLoS One. 2011;6:e17439.PubMedCentralCrossRefPubMed
15.
go back to reference Lindblade KA, Mwandama D, Mzilahowa T, Steinhardt L, Gimnig J, Shah M, et al. A cohort study of the effectiveness of insecticide-treated bed nets to prevent malaria in an area of moderate pyrethroid resistance, Malawi. Malar J. 2015;14:31.PubMedCentralCrossRefPubMed Lindblade KA, Mwandama D, Mzilahowa T, Steinhardt L, Gimnig J, Shah M, et al. A cohort study of the effectiveness of insecticide-treated bed nets to prevent malaria in an area of moderate pyrethroid resistance, Malawi. Malar J. 2015;14:31.PubMedCentralCrossRefPubMed
16.
go back to reference Lengeler C. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev. 2004;2:CD000363.PubMed Lengeler C. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev. 2004;2:CD000363.PubMed
17.
go back to reference Weatherly H, Drummond M, Claxton K, Cookson R, Ferguson B, Godfrey C, et al. Methods for assessing the cost-effectiveness of public health interventions: key challenges and recommendations. Health Policy Amst Neth. 2009;93:85–92.CrossRef Weatherly H, Drummond M, Claxton K, Cookson R, Ferguson B, Godfrey C, et al. Methods for assessing the cost-effectiveness of public health interventions: key challenges and recommendations. Health Policy Amst Neth. 2009;93:85–92.CrossRef
19.
go back to reference Kok MC, Dieleman M, Taegtmeyer M, Broerse JEW, Kane SS, Ormel H, et al. Which intervention design factors influence performance of community health workers in low- and middle-income countries? A systematic review. Health Policy Plan. 2014. doi:10.1093/heapol/czu126.PubMed Kok MC, Dieleman M, Taegtmeyer M, Broerse JEW, Kane SS, Ormel H, et al. Which intervention design factors influence performance of community health workers in low- and middle-income countries? A systematic review. Health Policy Plan. 2014. doi:10.​1093/​heapol/​czu126.PubMed
20.
go back to reference Lubell Y. Investment in malaria elimination: a leap of faith in need of direction. Lancet Glob Health. 2014;2:e63–4.CrossRefPubMed Lubell Y. Investment in malaria elimination: a leap of faith in need of direction. Lancet Glob Health. 2014;2:e63–4.CrossRefPubMed
21.
go back to reference Drake T. Priority setting in global health: towards a minimum DALY value. Health Econ. 2014;23:248–52.CrossRefPubMed Drake T. Priority setting in global health: towards a minimum DALY value. Health Econ. 2014;23:248–52.CrossRefPubMed
Metadata
Title
Cost effectiveness and resource allocation of Plasmodium falciparum malaria control in Myanmar: a modelling analysis of bed nets and community health workers
Authors
Tom L. Drake
Shwe Sin Kyaw
Myat Phone Kyaw
Frank M. Smithuis
Nicholas P. J. Day
Lisa J. White
Yoel Lubell
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2015
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-015-0886-x

Other articles of this Issue 1/2015

Malaria Journal 1/2015 Go to the issue