Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Malaria Journal
Published in: Malaria Journal 1/2015

Open Access 01-12-2015 | Research

Development of insecticide resistance in malaria vector Anopheles sinensis populations from Shandong province in China

Authors: Yuhua Dai, Xiaodan Huang, Peng Cheng, Lijuan Liu, Haifang Wang, Huaiwei Wang, Jingxuan Kou

Published in: Malaria Journal | Issue 1/2015

Login to get access

Abstract

Background

Anopheles sinensis is a major vector of malaria and among the dominant species in Shandong province of China. Insecticide resistance is an important threat to vector-borne disease control. However, there are only few reports about insecticide resistance of An. sinensis populations from Shandong province.

Methods

From 2003 to 2012, six districts in Shandong province were selected as the study areas. Insecticide susceptibility bioassay were tested on F1 progeny of An. sinensis to 4% DDT, 0.05% deltamethrin, 0.15% cyfluthrin, and 5% malathion, using the standard WHO resistance tube assay.

Results

The resistance status of An. sinensis showed a significant decrease in the mortality rates in DDT, deltamethrin and cyfluthrin during the past ten years. Whereas obvious increase of mortality to malathion was observed throughout the assay, ranging from 47.37% to 86.62%.
Literature
1.
Chareonviriyaphap T, Bangs MJ, Ratanatham S. Status of malaria in Thailand. Southeast Asian J Trop Med Public Health. 2000;31:225–37.PubMed
2.
Ma YJ, Yang MN, Fan Y, Wu J, Ma Y, Xu JN. Population structure of the malaria vector Anopheles sinensis (Diptera: Culicidae) in China: two gene pools inferred by microsatellites. PLoS One. 2011;6:e22219.CrossRefPubMedCentralPubMed
3.
Sinka ME, Bangs MJ, Manguin S, Chareonviriyaphap T, Patil AP, Temperley WH, et al. The dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic precis. Parasit Vectors. 2011;4:89.CrossRefPubMedCentralPubMed
4.
Zhen TM, Hu YX, Fan TB. [Distribution of mosquitoes from various topography in Shandong Province] (in Chinese). Chin J Parasitic Dis Control. 1990;3:319–21.
5.
Dai YH, Wang HF, Cheng P, Liu LJ, Zhao YQ, Wang HW, et al. Mosquito species (Diptera: Culicidae) reported from Shandong Province, China. J Entomol Sci. 2011;46:247–55.
6.
Van Bortel W, Trung HD, Thuan le K, Sochantha T, Socheat D, Sumrandee C, et al. The insecticide resistance status of malaria vectors in the Mekong region. Malar J. 2008;7:102.CrossRefPubMedCentralPubMed
7.
WHO. Global plan for insecticide resistance management in malaria vectors. Geneva, Switzerland: WHO Press, World Health Organization; 2012.
8.
Zhong DB, Chang XL, Zhou GF, He ZB, Fu FY, Yan ZT, et al. Relationship between knockdown resistance, metabolic detoxification and organismal resistance to pyrethroids in Anopheles sinensis. PLoS One. 2013;8:e55475.CrossRefPubMedCentralPubMed
9.
Wang DQ, Xia ZG, Zhou SS, Zhou XN, Wang RB, Zhang QF. A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China. Malar J. 2013;12:164.CrossRefPubMedCentralPubMed
10.
Pei SJ, Li KJ, Hu LQ. Field survey of resistance of Anopheles sinensis to deltamethrin in Hubei Province](in Chinese). Chin Trop Med. 2010;10:792–3.
11.
Zhou HY, Li JL, Jin XL, Wang WM, Zhu GD, Gu YP, et al. [Surveillance on Resistance of Anopheles Vectors to Pyrethroid in Jiangsu Province](in Chinese). Chin J Schistosomiasis Contr. 2004;16:199–201.
12.
Pan B, Zhu TH, Liu YY, Wu WG. [The main malaria vectors resistance to insecticide in China](in Chinese). Chin J Vector Biol Contr. 2001;12:145–8.
13.
Tan Y, Zhou WN, Zhou JG, Wang HB. [Rapid detection on the susceptibility of Anophelines to pyrethroids used in the impregnation of bed nets in Napo County, Guangxi](in Chinese). Chin J Parasitic Dis Contr. 2002;15:249–50.
14.
Liu Y, Chen JS, Zhou RM, Qian D, Chen QW, Xu BL, et al. [Investigation on the Sensitivity of Anopheles sinensis to Insecticides] (in Chinese). Chin J Parasit Dis Contr. 2012;30:309–11.
15.
WHO. Use of indoor residual spraying for scaling up global malaria control and elimination. Geneva, Switzerland: WHO position statement; 2006.
16.
Ministry of Health Disease Prevention and Control Bureau. Handbook for malaria control and prevention. Beijing: People’s Hygiene Publishing House Press; 2007.
17.
Dong X. The Mosquito Fauna of Yunnan (Volumes one). Yunnan Publishing Group Corporation, Yunnan Science & Technology Press: Kunming; 2010.
18.
WHO. Test procedures for insecticide resistance monitoring in malaria vector mosquitoes. Geneva, Switzerland: World Health Organization; 2013.
19.
Abbott WS. A method of computing the effectiveness of an insecticide. J Econ Entomol. 1925;18:265–7.CrossRef
20.
WHO. Report of the WHO informal consultation. Test procedures for insecticide resistance monitoring in malaria vectors, bio-efficacy and persistence of insecticides on treated surfaces. Geneva, Switzerland: WHO/CDS/CPC/MAL/98.12; 1998.
21.
Song W, Ma E-J, Qun L. Resistance of to deltamethrin in three counties of Hefei city (in Chinese). Chin J Vector Biol Contr. 2012;23:216–7.
22.
Zeng LH, Wang SQ, Sun DW, Zhao W, Li SG, Yang X. [Resistance assay of malaria vectors to four kinds of common insecticides in some endemic areas of Hainan Province](in Chinese). Chin J Parasitol Parasit Dis. 2011;29:200–3.
23.
Yu PH, Hu LQ, Liu LY, Huang GQ, Zhang HX, Chen H, et al. [The field investigation on the resistance of Anopheles in Jingshan, Anlu and Xiaochang of Hubei province](in Chinese). Chin J Vector Biol Contr. 2008;19:500–2.
24.
Li JL, Zhou HY, Cao J, Zhu GD, Wang WM, Gu Y, et al. [Sensitivity of to insecticides in Jiangsu Province](in Chinese). Chin J Schistosomiasis Contr. 2011;23:296–300.
25.
26.
Soderlund DM, Knipple DC. The molecular biology of knockdown resistance to pyrethroid insecticide. Insect Biochem Mol Biol. 2003;33:563–77.CrossRefPubMed
27.
Etang J, Manga L, Chandre F, Guillet P, Fondjo E, Mimpfoundi R, et al. Insecticide susceptibility status of Anopheles gambiae s.l. (Diptera: Culicidae) in the Republic of Cameroon. J Med Entomol. 2003;40:491–7.CrossRefPubMed
28.
Etang J, Fondjo E, Chandre F, Brengues C, Nwane P, Chouaibou M, et al. First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon. Am J Trop Med Hyg. 2006;74:795–7.PubMed
29.
Abdalla H, Matambo TS, Koekemoer LL. Insecticide susceptibility and vector status of natural populations of from Sudan. Trans R Soc Trop Med Hyg. 2008;102:263–71.CrossRefPubMed
30.
Nwane P, Etang J, Chouaibou M, Toto JC, Kerah-Hinzoumbé C, Mimpfoundi R, et al. Trends in DDT and pyrethroid resistance in Anopheles gambiae s.s. populations from urban and agro-industrial settings in southern Cameroon. BMC Infect Dis. 2009;9:163.CrossRefPubMedCentralPubMed
31.
Poupardin R, Reynaud S, Strode C, Ranson H, Vontas J, David JP. Cross-induction of detoxification genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: Impact on larval tolerance to chemical insecticides. Insect Biochem Mol Biol. 2008;38:540–51.CrossRefPubMed
32.
Riaz MA, Poupardin R, Reynaud S, Strode C, Ranson H, David JP. Impact of glyphosate and benzo[a]pyrene on the tolerance of mosquito larvae to chemical insecticides. Role of detoxification genes in response to xenobiotics. Aquat Toxicol. 2009;93:61–9.CrossRefPubMed
33.
Boyer S, David JP, Rey D, Lemperiere G, Ravanel P. Response of Aedes aegypti (Diptera: Culicidae) larvae to three xenobiotic exposures: larval tolerance and detoxifying enzyme activities. Environ Toxicol Chem. 2006;25:470–6.CrossRefPubMed
34.
Diabate A, Baldet T, Chandre F, Akoobeto M, Guiguemde TR, Darriet F, et al. The role of agricultural use of insecticides in resistance to pyrethroids in Anopheles gambiae s.l. in Burkina Faso. Am J Trop Med Hyg. 2002;67:617–22.PubMed
35.
Stump AD, Atieli FK, Vulule JM, Besansky NJ. Dynamics of the pyrethroid knockdown resistance allele in western Kenyan populations of Anopheles gambiae in response to insecticide-treated bed net trials. Am J Trop Med Hyg. 2004;70:591–6.PubMed
36.
Martinez-Torres D, Chandre F, Williamson MS, Darriet F, Berge JB, Devonshire AL, et al. Molecular characterisation of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s.s. Insect Mol Biol. 1998;7:179–84.CrossRefPubMed
37.
Bass C, Nikou D, Donnelly MJ, Williamson MS, Ranson H, Ball A, et al. Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods. Malar J. 2007;6:111.CrossRefPubMedCentralPubMed
38.
Brooke BD. Kdr: can a single mutation produce an entire insecticide resistance phenotype? Trans R Soc Trop Med Hyg. 2008;102:524–5.CrossRefPubMed
39.
Donnelly MJ, Corbel V, Weetman D, Wilding CS, Williamson MS, Black WC. Does kdr genotype predict insecticide-resistance phenotype in mosquitoes. Trends Parasitol. 2009;25:213–9.CrossRefPubMed
40.
Hemmingway J, Ranson H. Insecticide resistance in insect vectors of human disease. Annu Rev Entomol. 2000;45:371–91.CrossRef
41.
Georghiou GP, Pasteur N. Organophosphate resistance and esterase pattern in a natural population of the southern house mosquito from California. J Econ Entomol. 1980;73:489–92.CrossRef
42.
Alout H, Labbe P, Pasteur N, Weill M. High incidence of Ace1 duplicated haplotypes in resistant Culex pipiens mosquitoes from Algeria. Insect Biochem Mol Biol. 2011;41:29–35.CrossRefPubMed
43.
Fournier D, Mutero A. Modification of acetylcholinesterase as a mechanism of resistance to insecticides. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1994;108:19–31.CrossRef
44.
Huang J, Qiao F, Zhang L, Rozelle S. Farm pesticides, rice production, and human health in China. Singapore: Economy and Environment Program for Southeast Asia; 2001.
Metadata
Title
Development of insecticide resistance in malaria vector Anopheles sinensis populations from Shandong province in China
Authors
Yuhua Dai
Xiaodan Huang
Peng Cheng
Lijuan Liu
Haifang Wang
Huaiwei Wang
Jingxuan Kou
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2015
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-015-0592-8

Other articles of this Issue 1/2015

Malaria Journal 1/2015 Go to the issue

Commentary

Re-imagining the control of malaria in tropical Africa during the early years of the World Health Organization

Research

Direct and indirect determinants of childhood malaria morbidity in Malawi: a survey cross-sectional analysis based on malaria indicator survey data for 2012

Research

Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10

Research

Motivation and challenges for use of malaria rapid diagnostic tests among informal providers in Myanmar: a qualitative study

Meeting report

Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of seventh biannual meeting (March 2015)

Research

Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ–pfmdt gene polymorphism in French Guiana
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits