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Cardiovascular Diabetology
Published in: Cardiovascular Diabetology 1/2019

Open Access 01-12-2019 | Myocardial Infarction | Original investigation

High-intensity interval training improves metabolic syndrome and body composition in outpatient cardiac rehabilitation patients with myocardial infarction

Authors: Yaoshan Dun, Randal J. Thomas, Joshua R. Smith, Jose R. Medina-Inojosa, Ray W. Squires, Amanda R. Bonikowske, Hsuhang Huang, Suixin Liu, Thomas P. Olson

Published in: Cardiovascular Diabetology | Issue 1/2019

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Abstract

Background

To examine the effect of high-intensity interval training (HIIT) on metabolic syndrome (MetS) and body composition in cardiac rehabilitation (CR) patients with myocardial infarction (MI).

Methods

We retrospectively screened 174 consecutive patients with MetS enrolled in CR following MI between 2015 and 2018. We included 56 patients who completed 36 CR sessions and pre-post dual-energy X-ray absorptiometry. Of these patients, 42 engaged in HIIT and 14 in moderate-intensity continuous training (MICT). HIIT included 4–8 intervals of high-intensity (30–60 s at RPE 15–17 [Borg 6–20]) and low-intensity (1–5 min at RPE < 14), and MICT included 20–45 min of exercise at RPE 12–14. MetS and body composition variables were compared between MICT and HIIT groups.

Results

Compared to MICT, HIIT demonstrated greater reductions in MetS (relative risk = 0.5, 95% CI 0.33–0.75, P < .001), MetS z-score (− 3.6 ± 2.9 vs. − 0.8 ± 3.8, P < .001) and improved MetS components: waist circumference (− 3 ± 5 vs. 1 ± 5 cm, P = .01), fasting blood glucose (− 25.8 ± 34.8 vs. − 3.9 ± 25.8 mg/dl, P < .001), triglycerides (− 67.8 ± 86.7 vs. − 10.4 ± 105.3 mg/dl, P < .001), and diastolic blood pressure (− 7 ± 11 vs. 0 ± 13 mmHg, P = .001). HIIT group demonstrated greater reductions in body fat mass (− 2.1 ± 2.1 vs. 0 ± 2.2 kg, P = .002), with increased body lean mass (0.9 ± 1.9 vs. − 0.9 ± 3.2 kg, P = .01) than the MICT. After matching for exercise energy expenditure, HIIT-induced improvements persisted for MetS z-score (P < .001), MetS components (P < .05), body fat mass (P = .002), body fat (P = .01), and lean mass (P = .03).

Conclusions

Our data suggest that, compared to MICT, supervised HIIT results in greater improvements in MetS and body composition in MI patients with MetS undergoing CR.
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Metadata
Title
High-intensity interval training improves metabolic syndrome and body composition in outpatient cardiac rehabilitation patients with myocardial infarction
Authors
Yaoshan Dun
Randal J. Thomas
Joshua R. Smith
Jose R. Medina-Inojosa
Ray W. Squires
Amanda R. Bonikowske
Hsuhang Huang
Suixin Liu
Thomas P. Olson
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Cardiovascular Diabetology / Issue 1/2019
Electronic ISSN: 1475-2840
DOI
https://doi.org/10.1186/s12933-019-0907-0

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