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Respiratory Research
Published in: Respiratory Research 1/2017

Open Access 01-12-2017 | Review

Understanding the impact of symptoms on the burden of COPD

Authors: Marc Miravitlles, Anna Ribera

Published in: Respiratory Research | Issue 1/2017

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Abstract

Chronic obstructive pulmonary disease (COPD) imposes a substantial burden on individuals with the disease, which can include a range of symptoms (breathlessness, cough, sputum production, wheeze, chest tightness) of varying severities. We present an overview of the biomedical literature describing reported relationships between COPD symptoms and disease burden in terms of quality of life, health status, daily activities, physical activity, sleep, comorbid anxiety, and depression, as well as risk of exacerbations and disease prognosis. In addition, the substantial variability of COPD symptoms encountered (morning, daytime, and nighttime) is addressed and their implications for disease burden considered. The findings from this narrative review, which mainly focuses on real-world and observational studies, demonstrate the impact of COPD symptoms on the burden of disease and that improved recognition and understanding of their impact is central to alleviating this burden.
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Metadata
Title
Understanding the impact of symptoms on the burden of COPD
Authors
Marc Miravitlles
Anna Ribera
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Respiratory Research / Issue 1/2017
Electronic ISSN: 1465-993X
DOI
https://doi.org/10.1186/s12931-017-0548-3

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