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01-12-2021 | SARS-CoV-2 | Research article

A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious

Authors: Xiaomin Wu, Zengmiao Wang, Zhenyu He, Yapin Li, Yating Wu, Huaiji Wang, Yonghong Liu, Fanghua Hao, Huaiyu Tian

Published in: BMC Medicine | Issue 1/2021

Abstract

Background

Previous studies showed that recovered coronavirus disease 2019 (COVID-19) patients can have a subsequent positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after they are discharged from the hospital. Understanding the epidemiological characteristics of recovered COVID-19 patients who have a re-positive test is vital for preventing a second wave of COVID-19.

Methods

This retrospective study analyzed the epidemiological and clinical features of 20,280 COVID-19 patients from multiple centers in Wuhan who had a positive PCR test between December 31, 2019, and August 4, 2020. The RT-PCR test results for 4079 individuals who had close contact with the re-positive cases were also obtained.

Results

In total, 2466 (12.16%) of the 20,280 patients had a re-positive SARS-CoV-2 PCR test after they were discharged from the hospital, and 4079 individuals had close contact with members of this patient group. All of these 4079 individuals had a negative SARS-CoV-2 PCR test.

Conclusions

This retrospective study in Wuhan analyzed the basic characteristics of recovered COVID-19 patients with re-positive PCR test and found that these cases may not be infectious.

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Title: A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious
Authors: Xiaomin Wu
Zengmiao Wang
Zhenyu He
Yapin Li
Yating Wu
Huaiji Wang
Yonghong Liu
Fanghua Hao
Huaiyu Tian
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: SARS-CoV-2
COVID-19
Polymerase Chain Reaction
Published in: BMC Medicine / Issue 1/2021
Electronic ISSN: 1741-7015
DOI: https://doi.org/10.1186/s12916-021-01954-1

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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