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BMC Medicine
Published in: BMC Medicine 1/2015

Open Access 01-12-2015 | Review

Maternal undernutrition and cardiometabolic disease: a latin american perspective

Authors: Patricio Lopez-Jaramillo, Diego Gomez-Arbelaez, Aristides Sotomayor-Rubio, Daniel Mantilla-Garcia, Jose Lopez-Lopez

Published in: BMC Medicine | Issue 1/2015

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Abstract

The current epidemic of obesity and cardiometabolic diseases in developing countries is described as being driven by socioeconomic inequalities. These populations have a greater vulnerability to cardiometabolic diseases due to the discrepancy between the maternal undernutrition and its consequence, low-birth weight progeny, and the subsequent modern lifestyles which are associated with socioeconomic and environmental changes that modify dietary habits, discourage physical activity and encourage sedentary behaviors. Maternal undernutrition can generate epigenetic modifications, with potential long-term consequences. Throughout life, people are faced with the challenge of adapting to changes in their environment, such as excessive intake of high energy density foods and sedentary behavior. However, a mismatch between conditions experienced during fetal programming and current environmental conditions will make adaptation difficult for them, and will increase their susceptibility to obesity and cardiovascular diseases. It is important to conduct research in the Latin American context, in order to define the best strategies to prevent the epidemic of cardiometabolic diseases in the region.
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Metadata
Title
Maternal undernutrition and cardiometabolic disease: a latin american perspective
Authors
Patricio Lopez-Jaramillo
Diego Gomez-Arbelaez
Aristides Sotomayor-Rubio
Daniel Mantilla-Garcia
Jose Lopez-Lopez
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2015
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/s12916-015-0293-8

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