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BMC Health Services Research
Published in: BMC Health Services Research 1/2019

Open Access 01-12-2019 | Systemic Lupus Erythematosus | Research article

Lack of patient education is risk factor of disease flare in patients with systemic lupus erythematosus in China

Authors: Le Zhang, Wei Luan, Shikai Geng, Shuang Ye, Xiaodong Wang, Liping Qian, Yang Ding, Ting Li, Anli Jiang

Published in: BMC Health Services Research | Issue 1/2019

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Abstract

Background

To explore the inadequacies of health service and its impact on clinical outcomes of patients with systemic lupus erythematosus (SLE) in China.

Methods

A total of 210 SLE patients were randomly recruited between January 2017 and January 2018. Each patient received self-report questionnaires to assess medication adherence [Compliance Questionnaire for Rheumatology (CQR)], beliefs about medicines [Beliefs about Medicines Questionnaire (BMQ)] and satisfaction about medicine information [the Satisfaction with Information about Medicines Scale (SIMS)]. Associations between SLE disease activity index (SLEDAI-2 K) and observed factors were analyzed by multiple logistic regression.

Results

Based on CQR, only 28.10% patients were adherent. The score of BMQ was 2.85 ± 5.42, and merely 32.38% patients were satisfied with the information about their prescribed medicines. Disease activity was associated with SIMS, EuroQol five-dimensions [EQ5D], Systemic Lupus International Collaborating Clinics (SLICC), depression, use of NSAID (P ≤ 0.05). Remission of disease was positively correlated with SIMS (OR = 0.16, 95% CI: [0.06, 0.40]), and BMQ (OR = 0.64, 95%CI: [0.43, 0.94]).

Conclusion

In this study, the scores of BMQ and SIMS were low, implying defects in the patient education of health service system, which led to disease flare in Chinese SLE patients.

Trial registration

ClinicalTrials.gov ID: NCT03024307. Registered January 18, 2017.
Appendix
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Metadata
Title
Lack of patient education is risk factor of disease flare in patients with systemic lupus erythematosus in China
Authors
Le Zhang
Wei Luan
Shikai Geng
Shuang Ye
Xiaodong Wang
Liping Qian
Yang Ding
Ting Li
Anli Jiang
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2019
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-019-4206-y

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