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Published in: BMC Health Services Research 1/2018

Open Access 01-12-2018 | Research article

Health economic evaluations based on routine data in Germany: a systematic review

Author: Fabia Mareike Gansen

Published in: BMC Health Services Research | Issue 1/2018

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Abstract

Background

Improved data access and funding for health services research have promoted the application of routine data to measure costs and effects of interventions within the German health care system. Following the trend towards real world evidence, this review aims to evaluate the status and quality of health economic evaluations based on routine data in Germany.

Methods

To identify relevant economic evaluations, a systematic literature search in the databases PubMed and EMBASE was complemented by a manual search. The included studies had to be full economic evaluations using German routine data to measure either costs, effects, or both. Study characteristics were assessed with a structured template. Additionally, the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) were used to measure quality of reporting.

Results

In total, 912 records were identified and 35 studies were included in the further analysis. The majority of these studies was published in the past 5 years (n = 27, 77.1%) and used insurance claims data as a source of routine data (n = 30, 85.7%). The most common method used for handling selection bias was propensity score matching. With regard to the reporting quality, 42.9% (n = 15) of the studies satisfied at least 80% of the criteria on the CHEERS checklist.

Conclusions

This review confirms that routine data has become an increasingly common data source for health economic evaluations in Germany. While most studies addressed the application of routine data, this analysis reveals deficits in considering methodological particularities and in reporting quality of economic evaluations based on routine data. Nevertheless, this review demonstrates the overall potential of routine data for economic evaluations.
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Literature
1.
go back to reference Kreis K, Neubauer S, Klora M, Lange A, Zeidler J. Status and perspectives of claims data analyses in Germany: a systematic review. Health Policy. 2016;120(2):213–26.CrossRefPubMed Kreis K, Neubauer S, Klora M, Lange A, Zeidler J. Status and perspectives of claims data analyses in Germany: a systematic review. Health Policy. 2016;120(2):213–26.CrossRefPubMed
2.
go back to reference Bäumler M, Stargardt T, Schreyögg J, Busse R. Cost effectiveness of drug-eluting stents in acute myocardial infarction patients in Germany: results from administrative data using a propensity score-matching approach. Appl Health Econ Health Policy. 2012;10(4):235–48.CrossRefPubMed Bäumler M, Stargardt T, Schreyögg J, Busse R. Cost effectiveness of drug-eluting stents in acute myocardial infarction patients in Germany: results from administrative data using a propensity score-matching approach. Appl Health Econ Health Policy. 2012;10(4):235–48.CrossRefPubMed
3.
go back to reference Lange A, Kasperk C, Alvares L, Sauermann S, Braun S. Survival and cost comparison of kyphoplasty and percutaneous vertebroplasty using German claims data. Spine. 2014;39(4):318–26.CrossRefPubMed Lange A, Kasperk C, Alvares L, Sauermann S, Braun S. Survival and cost comparison of kyphoplasty and percutaneous vertebroplasty using German claims data. Spine. 2014;39(4):318–26.CrossRefPubMed
4.
go back to reference Reinhold T, Andersohn F, Hessel F, Brüggenjürgen B, Willich SN. Die Nutzung von Routinedaten der gesetzlichen Krankenkassen (GKV) zur Beantwortung gesundheitsökonomischer Fragestellungen - Eine Potenzialanalyse. Gesundheitsökonomie & Qualitätsmanagement. 2011;16(03):153–9.CrossRef Reinhold T, Andersohn F, Hessel F, Brüggenjürgen B, Willich SN. Die Nutzung von Routinedaten der gesetzlichen Krankenkassen (GKV) zur Beantwortung gesundheitsökonomischer Fragestellungen - Eine Potenzialanalyse. Gesundheitsökonomie & Qualitätsmanagement. 2011;16(03):153–9.CrossRef
5.
go back to reference Neubauer S, Kreis K, Klora M, Zeidler J. Access, use, and challenges of claims data analyses in Germany. Eur J Health Econ. 2017;18(5):533–6.CrossRefPubMed Neubauer S, Kreis K, Klora M, Zeidler J. Access, use, and challenges of claims data analyses in Germany. Eur J Health Econ. 2017;18(5):533–6.CrossRefPubMed
6.
go back to reference Brandes A, Schwarzkopf L, Rogowski WH. Using claims data for evidence generation in managed entry agreements. Int J Technol Assess Health Care. 2016;32(1–2):69–77.CrossRefPubMed Brandes A, Schwarzkopf L, Rogowski WH. Using claims data for evidence generation in managed entry agreements. Int J Technol Assess Health Care. 2016;32(1–2):69–77.CrossRefPubMed
7.
go back to reference Hoffmann F. Review on use of German health insurance medication claims data for epidemiological research. Pharmacoepidemiol Drug Saf. 2009;18(5):349–56.CrossRefPubMed Hoffmann F. Review on use of German health insurance medication claims data for epidemiological research. Pharmacoepidemiol Drug Saf. 2009;18(5):349–56.CrossRefPubMed
9.
go back to reference Schreyögg J, Stargardt T. Health economic evaluation based on administrative data from German health insurance. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012;55(5):668–74.CrossRefPubMed Schreyögg J, Stargardt T. Health economic evaluation based on administrative data from German health insurance. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012;55(5):668–74.CrossRefPubMed
10.
go back to reference Hoffmann F, Glaeske G. Analyse von Routinedaten. In: Pfaff H, Neugebauer E, Glaeske G, Schrappe M, editors. Lehrbuch Versorgungsforschung: Systematik - Methodik - Anwendung. Stuttgart: Schattauer; 2011. p. 317–22. Hoffmann F, Glaeske G. Analyse von Routinedaten. In: Pfaff H, Neugebauer E, Glaeske G, Schrappe M, editors. Lehrbuch Versorgungsforschung: Systematik - Methodik - Anwendung. Stuttgart: Schattauer; 2011. p. 317–22.
11.
go back to reference Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.CrossRefPubMedPubMedCentral Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.CrossRefPubMedPubMedCentral
13.
go back to reference Drummond MF, Sculpher MJ, Claxton K, Stoddart GL, Torrance GW. Methods for the economic evaluation of health care programmes. 4th ed. Oxford: Oxford University Press; 2015. Drummond MF, Sculpher MJ, Claxton K, Stoddart GL, Torrance GW. Methods for the economic evaluation of health care programmes. 4th ed. Oxford: Oxford University Press; 2015.
14.
15.
go back to reference Benchimol EI, Smeeth L, Guttmann A, Harron K, Moher D, Petersen I, et al. The REporting of studies conducted using observational routinely-collected health data (RECORD) statement. PLoS Med. 2015;12(10):e1001885.CrossRefPubMedPubMedCentral Benchimol EI, Smeeth L, Guttmann A, Harron K, Moher D, Petersen I, et al. The REporting of studies conducted using observational routinely-collected health data (RECORD) statement. PLoS Med. 2015;12(10):e1001885.CrossRefPubMedPubMedCentral
16.
go back to reference Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al. Consolidated health economic evaluation reporting standards (CHEERS) statement. Value Health. 2013;16(2):e1–5.CrossRefPubMed Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al. Consolidated health economic evaluation reporting standards (CHEERS) statement. Value Health. 2013;16(2):e1–5.CrossRefPubMed
17.
go back to reference Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al. Consolidated health economic evaluation reporting standards (CHEERS) - explanation and elaboration: a report of the ISPOR health economic evaluation publication guidelines good reporting practices task force. Value Health. 2013;16(2):231–50.CrossRefPubMed Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al. Consolidated health economic evaluation reporting standards (CHEERS) - explanation and elaboration: a report of the ISPOR health economic evaluation publication guidelines good reporting practices task force. Value Health. 2013;16(2):231–50.CrossRefPubMed
18.
go back to reference Abbas S, Ihle P, Hein R, Schubert I. Rehabilitation in geriatric patients after ischemic stroke - a comparison of 2 organisational systems in Germany using claims data of a statutory health insurance fund. Rehabilitation (Stuttg). 2013;52(6):375–82.CrossRef Abbas S, Ihle P, Hein R, Schubert I. Rehabilitation in geriatric patients after ischemic stroke - a comparison of 2 organisational systems in Germany using claims data of a statutory health insurance fund. Rehabilitation (Stuttg). 2013;52(6):375–82.CrossRef
19.
go back to reference Abbas S, Ihle P, Hein R, Schubert I. Comparison of rehabilitation between in-hospital geriatric departments and geriatric out-of-hospital rehabilitation facilities. Analysis of routine data using the example of femur fractures. Z Gerontol Geriatr. 2015;48(1):41–8. Abbas S, Ihle P, Hein R, Schubert I. Comparison of rehabilitation between in-hospital geriatric departments and geriatric out-of-hospital rehabilitation facilities. Analysis of routine data using the example of femur fractures. Z Gerontol Geriatr. 2015;48(1):41–8.
20.
go back to reference Achelrod D, Schreyogg J, Stargardt T. Health-economic evaluation of home telemonitoring for COPD in Germany: evidence from a large population-based cohort. Eur J Health Econ. 2017;18(7):869–82.CrossRefPubMed Achelrod D, Schreyogg J, Stargardt T. Health-economic evaluation of home telemonitoring for COPD in Germany: evidence from a large population-based cohort. Eur J Health Econ. 2017;18(7):869–82.CrossRefPubMed
21.
go back to reference Achelrod D, Welte T, Schreyogg J, Stargardt T. Costs and outcomes of the German disease management programme (DMP) for chronic obstructive pulmonary disease (COPD) - a large population-based cohort study. Health Policy. 2016;120(9):1029–39.CrossRefPubMed Achelrod D, Welte T, Schreyogg J, Stargardt T. Costs and outcomes of the German disease management programme (DMP) for chronic obstructive pulmonary disease (COPD) - a large population-based cohort study. Health Policy. 2016;120(9):1029–39.CrossRefPubMed
22.
go back to reference Aljutaili M, Becker C, Witt S, Holle R, Leidl R, Block M, et al. Should health insurers target prevention of cardiovascular disease? A cost-effectiveness analysis of an individualised programme in Germany based on routine data. BMC Health Serv Res. 2014;14:263.CrossRefPubMedPubMedCentral Aljutaili M, Becker C, Witt S, Holle R, Leidl R, Block M, et al. Should health insurers target prevention of cardiovascular disease? A cost-effectiveness analysis of an individualised programme in Germany based on routine data. BMC Health Serv Res. 2014;14:263.CrossRefPubMedPubMedCentral
23.
go back to reference Bäumler M, Sundmacher L, Reinhard T, Böhringer D. Cost-effectiveness of human leukocyte antigen matching in penetrating keratoplasty. Int J Technol Assess Health Care. 2014;30(1):50–8.CrossRef Bäumler M, Sundmacher L, Reinhard T, Böhringer D. Cost-effectiveness of human leukocyte antigen matching in penetrating keratoplasty. Int J Technol Assess Health Care. 2014;30(1):50–8.CrossRef
24.
go back to reference Bischoff-Everding C, Soeder R, Neukirch B. Economic and clinical benefits of endometrial radiofrequency ablation compared with other ablation techniques in women with menorrhagia: a retrospective analysis with German health claims data. Int J Womens Health. 2016;8:23–9.CrossRefPubMedPubMedCentral Bischoff-Everding C, Soeder R, Neukirch B. Economic and clinical benefits of endometrial radiofrequency ablation compared with other ablation techniques in women with menorrhagia: a retrospective analysis with German health claims data. Int J Womens Health. 2016;8:23–9.CrossRefPubMedPubMedCentral
25.
go back to reference Drabik A, Buscher G, Sawicki PT, Thomas K, Graf C, Muller D, et al. Life prolonging of disease management programs in patients with type 2 diabetes is cost-effective. Diabetes Res Clin Pract. 2012;95(2):194–200.CrossRefPubMed Drabik A, Buscher G, Sawicki PT, Thomas K, Graf C, Muller D, et al. Life prolonging of disease management programs in patients with type 2 diabetes is cost-effective. Diabetes Res Clin Pract. 2012;95(2):194–200.CrossRefPubMed
26.
go back to reference Drabik A, Buscher G, Thomas K, Graf C, Muller D, Stock S. Patients with type 2 diabetes benefit from primary care-based disease management: a propensity score matched survival time analysis. Popul Health Manag. 2012;15(4):241–7.CrossRefPubMed Drabik A, Buscher G, Thomas K, Graf C, Muller D, Stock S. Patients with type 2 diabetes benefit from primary care-based disease management: a propensity score matched survival time analysis. Popul Health Manag. 2012;15(4):241–7.CrossRefPubMed
27.
go back to reference Drabik A, Graf C, Buscher G, Stock S. Evaluating the effectiveness of a disease management program diabetes in the German statutory health insurance: first results and methodological considerations. Z Evid Fortbild Qual Gesundhwes. 2012;106(9):649–55.CrossRefPubMed Drabik A, Graf C, Buscher G, Stock S. Evaluating the effectiveness of a disease management program diabetes in the German statutory health insurance: first results and methodological considerations. Z Evid Fortbild Qual Gesundhwes. 2012;106(9):649–55.CrossRefPubMed
28.
go back to reference Driessen M, Veltrup C, Junghanns K, Przywara A, Dilling H. Cost-efficacy analysis of clinically evaluated therapeutic programs. An expanded withdrawal therapy in alcohol dependence. Nervenarzt. 1999;70(5):463–70.CrossRefPubMed Driessen M, Veltrup C, Junghanns K, Przywara A, Dilling H. Cost-efficacy analysis of clinically evaluated therapeutic programs. An expanded withdrawal therapy in alcohol dependence. Nervenarzt. 1999;70(5):463–70.CrossRefPubMed
29.
go back to reference Freund T, Peters-Klimm F, Boyd CM, Mahler C, Gensichen J, Erler A, et al. Medical assistant-based care management for high-risk patients in small primary care practices: a cluster randomized clinical trial. Ann Intern Med. 2016;164(5):323–30.CrossRefPubMed Freund T, Peters-Klimm F, Boyd CM, Mahler C, Gensichen J, Erler A, et al. Medical assistant-based care management for high-risk patients in small primary care practices: a cluster randomized clinical trial. Ann Intern Med. 2016;164(5):323–30.CrossRefPubMed
30.
go back to reference Frey S, Linder R, Juckel G, Stargardt T. Cost-effectiveness of long-acting injectable risperidone versus flupentixol decanoate in the treatment of schizophrenia: a Markov model parameterized using administrative data. Eur J Health Econ. 2014;15(2):133–42.CrossRefPubMed Frey S, Linder R, Juckel G, Stargardt T. Cost-effectiveness of long-acting injectable risperidone versus flupentixol decanoate in the treatment of schizophrenia: a Markov model parameterized using administrative data. Eur J Health Econ. 2014;15(2):133–42.CrossRefPubMed
31.
go back to reference Gaertner J, Drabik A, Marschall U, Schlesiger G, Voltz R, Stock S. Inpatient palliative care: a nationwide analysis. Health Policy. 2013;109(3):311–8.CrossRefPubMed Gaertner J, Drabik A, Marschall U, Schlesiger G, Voltz R, Stock S. Inpatient palliative care: a nationwide analysis. Health Policy. 2013;109(3):311–8.CrossRefPubMed
32.
go back to reference Goltz L, Degenhardt G, Maywald U, Kirch W, Schindler C. Evaluation of a program of integrated care to reduce recurrent osteoporotic fractures. Pharmacoepidemiol Drug Saf. 2013;22(3):263–70.CrossRefPubMed Goltz L, Degenhardt G, Maywald U, Kirch W, Schindler C. Evaluation of a program of integrated care to reduce recurrent osteoporotic fractures. Pharmacoepidemiol Drug Saf. 2013;22(3):263–70.CrossRefPubMed
33.
go back to reference Heinrich S, Rapp K, Stuhldreher N, Rissmann U, Becker C, Konig HH. Cost-effectiveness of a multifactorial fall prevention program in nursing homes. Osteoporos Int. 2013;24(4):1215–23.CrossRefPubMed Heinrich S, Rapp K, Stuhldreher N, Rissmann U, Becker C, Konig HH. Cost-effectiveness of a multifactorial fall prevention program in nursing homes. Osteoporos Int. 2013;24(4):1215–23.CrossRefPubMed
34.
go back to reference Hendricks V, Schmidt S, Vogt A, Gysan D, Latz V, Schwang I, et al. Case management program for patients with chronic heart failure: effectiveness in terms of mortality, hospital admissions and costs. Dtsch Arztebl Int. 2014;111(15):264–70.PubMedPubMedCentral Hendricks V, Schmidt S, Vogt A, Gysan D, Latz V, Schwang I, et al. Case management program for patients with chronic heart failure: effectiveness in terms of mortality, hospital admissions and costs. Dtsch Arztebl Int. 2014;111(15):264–70.PubMedPubMedCentral
35.
go back to reference Karmann A, Jurack A, Lukas D. Recommendation of rotavirus vaccination and herd effect: a budget impact analysis based on German health insurance data. Eur J Health Econ. 2015;16(7):719–31.CrossRefPubMed Karmann A, Jurack A, Lukas D. Recommendation of rotavirus vaccination and herd effect: a budget impact analysis based on German health insurance data. Eur J Health Econ. 2015;16(7):719–31.CrossRefPubMed
36.
go back to reference Kessel S, Hucke J, Goergen C, Soeder R, Roemer T. Economic and clinical benefits of radiofrequency ablation versus hysterectomy in patients suffering from menorrhagia: a retrospective analysis with German health claims data. Expert Rev Med Devices. 2015;12(3):365–72.CrossRefPubMed Kessel S, Hucke J, Goergen C, Soeder R, Roemer T. Economic and clinical benefits of radiofrequency ablation versus hysterectomy in patients suffering from menorrhagia: a retrospective analysis with German health claims data. Expert Rev Med Devices. 2015;12(3):365–72.CrossRefPubMed
37.
go back to reference Kottmair S, Frye C, Ziegenhagen DJ. Germany's disease management program: improving outcomes in congestive heart failure. Health Care Financ Rev. 2005;27(1):79–87.PubMedPubMedCentral Kottmair S, Frye C, Ziegenhagen DJ. Germany's disease management program: improving outcomes in congestive heart failure. Health Care Financ Rev. 2005;27(1):79–87.PubMedPubMedCentral
38.
go back to reference Laux G, Kaufmann-Kolle P, Bauer E, Goetz K, Stock C, Szecsenyi J. Evaluation of family doctor centred medical care based on AOK routine data in Baden-Wurttemberg. Z Evid Fortbild Qual Gesundhwes. 2013;107(6):372–8.CrossRefPubMed Laux G, Kaufmann-Kolle P, Bauer E, Goetz K, Stock C, Szecsenyi J. Evaluation of family doctor centred medical care based on AOK routine data in Baden-Wurttemberg. Z Evid Fortbild Qual Gesundhwes. 2013;107(6):372–8.CrossRefPubMed
39.
go back to reference Linder R, Ahrens S, Koppel D, Heilmann T, Verheyen F. The benefit and efficiency of the disease management program for type 2 diabetes. Dtsch Arztebl Int. 2011;108(10):155–62.PubMedPubMedCentral Linder R, Ahrens S, Koppel D, Heilmann T, Verheyen F. The benefit and efficiency of the disease management program for type 2 diabetes. Dtsch Arztebl Int. 2011;108(10):155–62.PubMedPubMedCentral
40.
go back to reference Niedhart C, Preising A, Eichhorn C. Significant reduction of osteoporosis fracture-related hospitalisation rate due to intensified, multimodal treatment - results from the integrated health care network osteoporosis North Rhine. Zeitschrift fur Orthopadie und Unfallchirurgie. 2013;151(1):20–4.PubMed Niedhart C, Preising A, Eichhorn C. Significant reduction of osteoporosis fracture-related hospitalisation rate due to intensified, multimodal treatment - results from the integrated health care network osteoporosis North Rhine. Zeitschrift fur Orthopadie und Unfallchirurgie. 2013;151(1):20–4.PubMed
41.
go back to reference Rossaint R, Christensen MC, Choong PI, Boffard KD, Riou B, Rizoli S, et al. Cost-effectiveness of recombinant activated factor VII as adjunctive therapy for bleeding control in severely injured trauma patients in Germany. Eur J Trauma Emerg Surg. 2007;33(5):528–38.CrossRefPubMed Rossaint R, Christensen MC, Choong PI, Boffard KD, Riou B, Rizoli S, et al. Cost-effectiveness of recombinant activated factor VII as adjunctive therapy for bleeding control in severely injured trauma patients in Germany. Eur J Trauma Emerg Surg. 2007;33(5):528–38.CrossRefPubMed
42.
go back to reference Schneider U, Linder R, Verheyen F. Long-term sick leave and graded return to work: what do we know about the follow-up effects? Health Policy. 2016;120(10):1193–201.CrossRefPubMed Schneider U, Linder R, Verheyen F. Long-term sick leave and graded return to work: what do we know about the follow-up effects? Health Policy. 2016;120(10):1193–201.CrossRefPubMed
43.
go back to reference Schulte T, Mund M, Hofmann L, Pimperl A, Dittmann B, Hildebrandt H. A pilot study to evaluate the DMP for coronary heart disease - development of a methodology and first results. Z Evid Fortbild Qual Gesundhwes. 2016;110-111:54–9.CrossRefPubMed Schulte T, Mund M, Hofmann L, Pimperl A, Dittmann B, Hildebrandt H. A pilot study to evaluate the DMP for coronary heart disease - development of a methodology and first results. Z Evid Fortbild Qual Gesundhwes. 2016;110-111:54–9.CrossRefPubMed
44.
go back to reference Shearer AT, Bagust A, Liebl A, Schoeffski O, Goertz A. Cost-effectiveness of rosiglitazone oral combination for the treatment of type 2 diabetes in Germany. PharmacoEconomics. 2006;24(Suppl 1):35–48.CrossRefPubMed Shearer AT, Bagust A, Liebl A, Schoeffski O, Goertz A. Cost-effectiveness of rosiglitazone oral combination for the treatment of type 2 diabetes in Germany. PharmacoEconomics. 2006;24(Suppl 1):35–48.CrossRefPubMed
45.
go back to reference Stargardt T, Edel MA, Ebert A, Busse R, Juckel G, Gericke CA. Effectiveness and cost of atypical versus typical antipsychotic treatment in a nationwide cohort of patients with schizophrenia in Germany. J Clin Psychopharmacol. 2012;32(5):602–7.CrossRefPubMed Stargardt T, Edel MA, Ebert A, Busse R, Juckel G, Gericke CA. Effectiveness and cost of atypical versus typical antipsychotic treatment in a nationwide cohort of patients with schizophrenia in Germany. J Clin Psychopharmacol. 2012;32(5):602–7.CrossRefPubMed
46.
go back to reference Stargardt T, Mavrogiorgou P, Gericke CA, Juckel G. Effectiveness and costs of flupentixol compared to other first- and second-generation antipsychotics in the treatment of schizophrenia. Psychopharmacology. 2011;216(4):579–87.CrossRefPubMed Stargardt T, Mavrogiorgou P, Gericke CA, Juckel G. Effectiveness and costs of flupentixol compared to other first- and second-generation antipsychotics in the treatment of schizophrenia. Psychopharmacology. 2011;216(4):579–87.CrossRefPubMed
47.
go back to reference Stargardt T, Weinbrenner S, Busse R, Juckel G, Gericke CA. Effectiveness and cost of atypical versus typical antipsychotic treatment for schizophrenia in routine care. J Ment Health Policy Econ. 2008;11(2):89–97.PubMed Stargardt T, Weinbrenner S, Busse R, Juckel G, Gericke CA. Effectiveness and cost of atypical versus typical antipsychotic treatment for schizophrenia in routine care. J Ment Health Policy Econ. 2008;11(2):89–97.PubMed
48.
go back to reference Steinke S, Gutknecht M, Zeidler C, Dieckhofer AM, Herrlein O, Luling H, et al. Cost-effectiveness of an 8% capsaicin patch in the treatment of brachioradial pruritus and notalgia paraesthetica, two forms of neuropathic pruritus. Acta Derm Venereol. 2017;97(1):71–76.CrossRefPubMed Steinke S, Gutknecht M, Zeidler C, Dieckhofer AM, Herrlein O, Luling H, et al. Cost-effectiveness of an 8% capsaicin patch in the treatment of brachioradial pruritus and notalgia paraesthetica, two forms of neuropathic pruritus. Acta Derm Venereol. 2017;97(1):71–76.CrossRefPubMed
49.
go back to reference Stock S, Drabik A, Buscher G, Graf C, Ullrich W, Gerber A, et al. German diabetes management programs improve quality of care and curb costs. Health Aff (Millwood). 2010;29(12):2197–205.CrossRef Stock S, Drabik A, Buscher G, Graf C, Ullrich W, Gerber A, et al. German diabetes management programs improve quality of care and curb costs. Health Aff (Millwood). 2010;29(12):2197–205.CrossRef
50.
go back to reference Walter J, Vogl M, Holderried M, Becker C, Brandes A, Sinner MF, et al. Manual compression versus vascular closing device for closing access puncture site in femoral left-heart catheterization and percutaneous coronary interventions: a retrospective cross-sectional comparison of costs and effects in inpatient care. Value Health. 2017;20(6):769–76.CrossRefPubMed Walter J, Vogl M, Holderried M, Becker C, Brandes A, Sinner MF, et al. Manual compression versus vascular closing device for closing access puncture site in femoral left-heart catheterization and percutaneous coronary interventions: a retrospective cross-sectional comparison of costs and effects in inpatient care. Value Health. 2017;20(6):769–76.CrossRefPubMed
51.
go back to reference Rosenbaum PR, Rubin DB. The central role of the propensity score in observational studies for causal effects. Biometrika. 1983;70(1):41–55.CrossRef Rosenbaum PR, Rubin DB. The central role of the propensity score in observational studies for causal effects. Biometrika. 1983;70(1):41–55.CrossRef
52.
go back to reference van Lente EJ, Willenborg P. Erfahrungen mit strukturierten Behandlungsprogrammen (DMPs) in Deutschland. Einleitung. In: Günster C, Klose J, Schmacke N, editors. Versorgungs-Report 2011 Schwerpunkt: Chronische Erkrankungen. Stuttgart: Schattauer; 2011. p. 56–62. van Lente EJ, Willenborg P. Erfahrungen mit strukturierten Behandlungsprogrammen (DMPs) in Deutschland. Einleitung. In: Günster C, Klose J, Schmacke N, editors. Versorgungs-Report 2011 Schwerpunkt: Chronische Erkrankungen. Stuttgart: Schattauer; 2011. p. 56–62.
53.
go back to reference Hintzpeter B, List SM, Lampert T, Ziese T. Entwicklung chronischer Krankheiten. In: Günster C, Klose J, Schmacke N, editors. Versorgungs-Report 2011 Schwerpunkt: Chronische Erkrankungen. Stuttgart: Schattauer; 2011. p. 3–28. Hintzpeter B, List SM, Lampert T, Ziese T. Entwicklung chronischer Krankheiten. In: Günster C, Klose J, Schmacke N, editors. Versorgungs-Report 2011 Schwerpunkt: Chronische Erkrankungen. Stuttgart: Schattauer; 2011. p. 3–28.
Metadata
Title
Health economic evaluations based on routine data in Germany: a systematic review
Author
Fabia Mareike Gansen
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2018
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-018-3080-3

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