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BMC Health Services Research
Published in: BMC Health Services Research 1/2014

Open Access 01-12-2014 | Research article

Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant

Authors: Karl Philipp Drewitz, Martin Loss, Julika Loss, Christian Joachim Apfelbacher

Published in: BMC Health Services Research | Issue 1/2014

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Abstract

Background

The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany.

Methods

Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for multivariate modelling. Socio-demographic and medical factors were considered as independent variables in logistic regression models with non-transplantation as dependent variable.

Results

Male gender, advanced age, overweight/obesity, long ICU stay, a history of smoking, non-traumatic brain death, elevated levels of sodium, serum glucose, lipase/amylase and the liver not being considered for procurement were significant independent predictors of non-transplantation.

Conclusion

In line with previous research, advanced age, high BMI, long ICU stay and the liver not being considered for procurement were the strongest predictors of pancreas non-transplantation in Germany. About three quarters of the variance remained unexplained, suggesting that factors not assessed or unknown may play a decisive role.
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Metadata
Title
Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant
Authors
Karl Philipp Drewitz
Martin Loss
Julika Loss
Christian Joachim Apfelbacher
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2014
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-014-0584-3

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