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Published in: BMC Surgery 1/2013

Open Access 01-12-2013 | Research article

Accept or refuse? Factors influencing the decision-making of transplant surgeons who are offered a pancreas: results of a qualitative study

Authors: Julika Loss, Karl P Drewitz, Hans J Schlitt, Martin Loss

Published in: BMC Surgery | Issue 1/2013

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Abstract

Background

Most offered pancreases are not transplanted. This study investigates the factors that inform and influence the transplant surgeon’s decision to select an offered pancreas.

Methods

Semi-standardized interviews were conducted with 14 highly qualified transplant surgeons from all 14 German transplant centers performing > 5 pancreas transplantations per year. The interviews focused on medical and non-medical criteria on which the individual accept/refuse decision depends. Interviews were recorded, transcribed and underwent content analysis.

Results

The interviewees agreed upon certain main selection criteria, e.g. donor age, lab results, ICU stay. However, there was no consistency in judging these parameters, and clear cut-offs did not exist. The pancreas macroscopy is a pivotal factor, as well as knowing (and trusting) the donor surgeon. 3/14 surgeons reported that they had occasionally refused a pancreas because of staff shortage. Some interviewees followed a restrictive acceptance policy, whereas others preferred to accept almost any pancreas and inspect it personally before deciding.

Conclusion

The assessment of medical donor characteristics is highly inconsistent. Both very cautious as well as very permissive acceptance policies may render the allocation process less efficient. A more standardized policy should be discussed. Finally, better training for donor surgeons seems advisable, in order to increase trust and thus pancreas utilization.
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Literature
1.
go back to reference Landgraf R: Impact of pancreas transplantation on diabetic secondary complications and quality of life. Diabetologia. 1996, 39 (12): 1415-1424. 10.1007/s001250050593.CrossRefPubMed Landgraf R: Impact of pancreas transplantation on diabetic secondary complications and quality of life. Diabetologia. 1996, 39 (12): 1415-1424. 10.1007/s001250050593.CrossRefPubMed
2.
go back to reference Katz H, Homan M, Velosa J, Robertson P, Rizza R: Effects of pancreas transplantation on postprandial glucose metabolism. N Engl J Med. 1991, 325 (18): 1278-1283. 10.1056/NEJM199110313251804.CrossRefPubMed Katz H, Homan M, Velosa J, Robertson P, Rizza R: Effects of pancreas transplantation on postprandial glucose metabolism. N Engl J Med. 1991, 325 (18): 1278-1283. 10.1056/NEJM199110313251804.CrossRefPubMed
3.
go back to reference Venstrom JM, McBride MA, Rother KI, Hirshberg B, Orchard TJ, Harlan DM: Survival after pancreas transplantation in patients with diabetes and preserved kidney function. JAMA. 2003, 290 (21): 2817-2823. 10.1001/jama.290.21.2817.CrossRefPubMed Venstrom JM, McBride MA, Rother KI, Hirshberg B, Orchard TJ, Harlan DM: Survival after pancreas transplantation in patients with diabetes and preserved kidney function. JAMA. 2003, 290 (21): 2817-2823. 10.1001/jama.290.21.2817.CrossRefPubMed
4.
go back to reference Gruessner RWG, Sutherland DER, Gruessner AC: Mortality assessment for pancreas transplants. Am J Transplant. 2004, 4 (12): 2018-2026. 10.1111/j.1600-6143.2004.00667.x.CrossRefPubMed Gruessner RWG, Sutherland DER, Gruessner AC: Mortality assessment for pancreas transplants. Am J Transplant. 2004, 4 (12): 2018-2026. 10.1111/j.1600-6143.2004.00667.x.CrossRefPubMed
5.
go back to reference Smets YF, Westendorp RG, van der Pijl JW, de Charro FT, Ringers J, de Fijter JW, Lemkes HH: Effect of simultaneous pancreas-kidney transplantation on mortality of patients with type-1 diabetes mellitus and end-stage renal failure. Lancet. 1999, 353 (9168): 1915-1919. 10.1016/S0140-6736(98)07513-8.CrossRefPubMed Smets YF, Westendorp RG, van der Pijl JW, de Charro FT, Ringers J, de Fijter JW, Lemkes HH: Effect of simultaneous pancreas-kidney transplantation on mortality of patients with type-1 diabetes mellitus and end-stage renal failure. Lancet. 1999, 353 (9168): 1915-1919. 10.1016/S0140-6736(98)07513-8.CrossRefPubMed
6.
go back to reference Ojo AO, Meier-Kriesche HU, Hanson JA, Leichtman A, Magee JC, Cibrik D, Wolfe RA, Port FK, Agodoa L, Kaufman DB, et al: The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation. 2001, 71 (1): 82-90. 10.1097/00007890-200101150-00014.CrossRefPubMed Ojo AO, Meier-Kriesche HU, Hanson JA, Leichtman A, Magee JC, Cibrik D, Wolfe RA, Port FK, Agodoa L, Kaufman DB, et al: The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation. 2001, 71 (1): 82-90. 10.1097/00007890-200101150-00014.CrossRefPubMed
7.
go back to reference Oosterlee A, Rahmel AO: Eurotransplant international foundation annual report 2010. 2011, Leiden: Foundation EI Oosterlee A, Rahmel AO: Eurotransplant international foundation annual report 2010. 2011, Leiden: Foundation EI
8.
go back to reference Hudson AJ, Watson CJE, on behalf of the UK Transplant Pancreas Task Force: UK pancreas transplantation: Ten year trends and recent outcomes. In: British transplantation society (BTS). 2005, Belfast, Northern Ireland Hudson AJ, Watson CJE, on behalf of the UK Transplant Pancreas Task Force: UK pancreas transplantation: Ten year trends and recent outcomes. In: British transplantation society (BTS). 2005, Belfast, Northern Ireland
9.
go back to reference Loss M, Drewitz KP, Apfelbacher CJ, van Rosmalen MD, Rahmel A, Schlitt HJ, Loss J: Why offered pancreases are refused in the allocation process-a descriptive study using routine data from eurotransplant. Transplantation. 2013, 95 (9): 1134-1141. 10.1097/TP.0b013e318287d83f.CrossRefPubMed Loss M, Drewitz KP, Apfelbacher CJ, van Rosmalen MD, Rahmel A, Schlitt HJ, Loss J: Why offered pancreases are refused in the allocation process-a descriptive study using routine data from eurotransplant. Transplantation. 2013, 95 (9): 1134-1141. 10.1097/TP.0b013e318287d83f.CrossRefPubMed
10.
go back to reference Howard DH: Why do transplant surgeons turn down organs? A model of the accept/reject decision. J Health Econ. 2002, 21 (6): 957-969. 10.1016/S0167-6296(02)00077-2.CrossRefPubMed Howard DH: Why do transplant surgeons turn down organs? A model of the accept/reject decision. J Health Econ. 2002, 21 (6): 957-969. 10.1016/S0167-6296(02)00077-2.CrossRefPubMed
11.
go back to reference Deutsche Stiftung Organtransplantation: Organspende und transplantation in deutschland. 2010, Frankfurt/Main: Deutsche Stiftung Organtransplantation, 2011- Deutsche Stiftung Organtransplantation: Organspende und transplantation in deutschland. 2010, Frankfurt/Main: Deutsche Stiftung Organtransplantation, 2011-
12.
go back to reference Patton MQ: Qualitative evaluation and research methods. 1990, Newbury Park: SAGE Publications, 2 Patton MQ: Qualitative evaluation and research methods. 1990, Newbury Park: SAGE Publications, 2
13.
14.
15.
go back to reference Andreoni KA, Brayman KL, Guidinger MK, Sommers CM, Sung RS: Kidney and pancreas transplantation in the united states, 1996–2005. Am J Transplant. 2007, 7 (5): 1359-1375.CrossRefPubMed Andreoni KA, Brayman KL, Guidinger MK, Sommers CM, Sung RS: Kidney and pancreas transplantation in the united states, 1996–2005. Am J Transplant. 2007, 7 (5): 1359-1375.CrossRefPubMed
16.
go back to reference Patton MQ: Qualitative research and evaluation methods. 2002, Thousand Oaks, Calif: Sage Publications, 3 Patton MQ: Qualitative research and evaluation methods. 2002, Thousand Oaks, Calif: Sage Publications, 3
17.
go back to reference Wullstein C, Woeste G, de Vries E, Persijn GG, Bechstein WO: Acceptance criteria of pancreas grafts: how do surgeons decide in europe?. Transplant Proc. 2005, 37 (2): 1259-1261. 10.1016/j.transproceed.2004.12.146.CrossRefPubMed Wullstein C, Woeste G, de Vries E, Persijn GG, Bechstein WO: Acceptance criteria of pancreas grafts: how do surgeons decide in europe?. Transplant Proc. 2005, 37 (2): 1259-1261. 10.1016/j.transproceed.2004.12.146.CrossRefPubMed
18.
go back to reference Wiseman AC, Wainright JL, Sleeman E, McBride MA, Baker T, Samana C, Stock P: An analysis of the lack of donor pancreas utilization from younger adult organ donors. Transplantation. 2010, 90 (5): 475-480. 10.1097/TP.0b013e3181e9fea4.CrossRefPubMed Wiseman AC, Wainright JL, Sleeman E, McBride MA, Baker T, Samana C, Stock P: An analysis of the lack of donor pancreas utilization from younger adult organ donors. Transplantation. 2010, 90 (5): 475-480. 10.1097/TP.0b013e3181e9fea4.CrossRefPubMed
19.
go back to reference Farid S, Aldouri A, Fraser S, Al-Mukhtar A, Newstead C, Lewington A, Baker R, Menon K, Ahmad N: Outcomes of kidney grafts refused by one or more centers and subsequently transplanted at a single united kingdom center. Transplant Proc. 2009, 41 (5): 1541-1546. 10.1016/j.transproceed.2009.01.088.CrossRefPubMed Farid S, Aldouri A, Fraser S, Al-Mukhtar A, Newstead C, Lewington A, Baker R, Menon K, Ahmad N: Outcomes of kidney grafts refused by one or more centers and subsequently transplanted at a single united kingdom center. Transplant Proc. 2009, 41 (5): 1541-1546. 10.1016/j.transproceed.2009.01.088.CrossRefPubMed
20.
go back to reference Wolfe RA, LaPorte FB, Rodgers AM, Roys EC, Fant G, Leichtman AB: Developing organ offer and acceptance measures: when ‘good’ organs are turned down. Am J Transplant. 2007, 7 (5 Pt 2): 1404-1411.CrossRefPubMed Wolfe RA, LaPorte FB, Rodgers AM, Roys EC, Fant G, Leichtman AB: Developing organ offer and acceptance measures: when ‘good’ organs are turned down. Am J Transplant. 2007, 7 (5 Pt 2): 1404-1411.CrossRefPubMed
21.
go back to reference Maglione M, Ploeg RJ, Friend PJ: Donor risk factors, retrieval technique, preservation and ischemia/reperfusion injury in pancreas transplantation. Curr Opin Organ Transplant. 2013, 18 (1): 83-88. 10.1097/MOT.0b013e32835c29ef.CrossRefPubMed Maglione M, Ploeg RJ, Friend PJ: Donor risk factors, retrieval technique, preservation and ischemia/reperfusion injury in pancreas transplantation. Curr Opin Organ Transplant. 2013, 18 (1): 83-88. 10.1097/MOT.0b013e32835c29ef.CrossRefPubMed
Metadata
Title
Accept or refuse? Factors influencing the decision-making of transplant surgeons who are offered a pancreas: results of a qualitative study
Authors
Julika Loss
Karl P Drewitz
Hans J Schlitt
Martin Loss
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2013
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/1471-2482-13-47

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