Skip to main content
Top
Published in: BMC Medical Informatics and Decision Making 1/2019

Open Access 01-12-2019 | Atrial Fibrillation | Research article

Atrial fibrillation classification based on convolutional neural networks

Authors: Kwang-Sig Lee, Sunghoon Jung, Yeongjoon Gil, Ho Sung Son

Published in: BMC Medical Informatics and Decision Making | Issue 1/2019

Login to get access

Abstract

Background

The global age-adjusted mortality rate related to atrial fibrillation (AF) registered a rapid growth in the last four decades, i.e., from 0.8 to 1.6 and 0.9 to 1.7 per 100,000 for men and women during 1990–2010, respectively. In this context, this study uses convolutional neural networks for classifying (diagnosing) AF, employing electrocardiogram data in a general hospital.

Methods

Data came from Anam Hospital in Seoul, Korea, with 20,000 unique patients (10,000 normal sinus rhythm and 10,000 AF). 30 convolutional neural networks were applied and compared for the diagnosis of the normal sinus rhythm vs. AF condition: 6 Alex networks with 5 convolutional layers, 3 fully connected layers and the number of kernels changing from 3 to 256; and 24 residual networks with the number of residuals blocks (or kernels) varying from 8 to 2 (or 64 to 2).

Results

In terms of the accuracy, the best Alex network was one with 24 initial kernels (i.e., kernels in the first layer), 5,268,818 parameters and the training time of 89 s (0.997), while the best residual network was one with 6 residual blocks, 32 initial kernels, 248,418 parameters and the training time of 253 s (0.999). In general, the performance of the residual network improved as the number of its residual blocks (its depth) increased.

Conclusion

For AF diagnosis, the residual network might be a good model with higher accuracy and fewer parameters than its Alex-network counterparts.
Appendix
Available only for authorised users
Literature
1.
go back to reference Roth GA, Huffman MD, Moran AE, Feigin V, Mensah GA, Naghavi M, Murray CJ. Global and regional patterns in cardiovascular mortality from 1990 to 2013. Circulation. 2015;132(17):1667–78.CrossRef Roth GA, Huffman MD, Moran AE, Feigin V, Mensah GA, Naghavi M, Murray CJ. Global and regional patterns in cardiovascular mortality from 1990 to 2013. Circulation. 2015;132(17):1667–78.CrossRef
2.
go back to reference Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, et al. Worldwide epidemiology of atrial fibrillation: a global burden of disease 2010 study. Circulation. 2014;129(8):837–47.CrossRef Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, et al. Worldwide epidemiology of atrial fibrillation: a global burden of disease 2010 study. Circulation. 2014;129(8):837–47.CrossRef
3.
go back to reference Korea S. Year 2016 statistics on causes of death in Korea. Sejong: Statistics Korea; 2017. Korea S. Year 2016 statistics on causes of death in Korea. Sejong: Statistics Korea; 2017.
4.
go back to reference Lee KS, Park JH. Burden of disease in Korea during 2000-10. J Public Health (Oxf). 2014;36(2):225–34.CrossRef Lee KS, Park JH. Burden of disease in Korea during 2000-10. J Public Health (Oxf). 2014;36(2):225–34.CrossRef
5.
go back to reference Kim D, Yang PS, Jang E, Yu HT, Kim TH, Uhm JS, et al. Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015. Heart. 2018;104(24):2010–7.CrossRef Kim D, Yang PS, Jang E, Yu HT, Kim TH, Uhm JS, et al. Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015. Heart. 2018;104(24):2010–7.CrossRef
6.
go back to reference Isin A, Ozdalili S. Cardiac arrhythmia detection using deep learning. Procedia Comput Sci. 2017;120:268–75.CrossRef Isin A, Ozdalili S. Cardiac arrhythmia detection using deep learning. Procedia Comput Sci. 2017;120:268–75.CrossRef
9.
go back to reference Sannino G, De Pietro G. A deep learning approach for ECG-based heartbeat classification for arrhythmia detection. Futur Gener Comput Syst. 2018;86:446–55.CrossRef Sannino G, De Pietro G. A deep learning approach for ECG-based heartbeat classification for arrhythmia detection. Futur Gener Comput Syst. 2018;86:446–55.CrossRef
11.
13.
go back to reference Krizhevsky A, Sutskever I, Hinton GE. ImageNet classification with deep convolutional neural networks. Proceedings of the 25th International Conference on Neural Information Processing Systems. 2012;1:1097–105. Krizhevsky A, Sutskever I, Hinton GE. ImageNet classification with deep convolutional neural networks. Proceedings of the 25th International Conference on Neural Information Processing Systems. 2012;1:1097–105.
14.
go back to reference Han J, Micheline K. Data mining: concepts and techniques. 2nd ed. San Francisco: Elsevier; 2006. Han J, Micheline K. Data mining: concepts and techniques. 2nd ed. San Francisco: Elsevier; 2006.
16.
go back to reference Schläpfer J, Wellens HJ. Computer-interpreted electrocardiograms: benefits and limitations. J Am Coll Cardiol. 2017;70(9):1183–92.CrossRef Schläpfer J, Wellens HJ. Computer-interpreted electrocardiograms: benefits and limitations. J Am Coll Cardiol. 2017;70(9):1183–92.CrossRef
Metadata
Title
Atrial fibrillation classification based on convolutional neural networks
Authors
Kwang-Sig Lee
Sunghoon Jung
Yeongjoon Gil
Ho Sung Son
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Medical Informatics and Decision Making / Issue 1/2019
Electronic ISSN: 1472-6947
DOI
https://doi.org/10.1186/s12911-019-0946-1

Other articles of this Issue 1/2019

BMC Medical Informatics and Decision Making 1/2019 Go to the issue