Skip to main content
Top
Published in: BMC Complementary Medicine and Therapies 1/2018

Open Access 01-12-2018 | Research article

A survey of Korean medicine doctors’ clinical practice patterns for autism spectrum disorder: preliminary research for clinical practice guidelines

Authors: Jihong Lee, Sun Haeng Lee, Boram Lee, In Jun Yang, Gyu Tae Chang

Published in: BMC Complementary Medicine and Therapies | Issue 1/2018

Login to get access

Abstract

Background

The aim of this study was to investigate autism spectrum disorder (ASD) clinical practice patterns of Korean medicine doctors (KMDs) through questionnaire survey.

Methods

Questionnaires on Korean medicine (KM) treatment for ASD were distributed to 255 KMDs on December 5, 2016. The KMDs were psychiatrists, pediatricians, or general practitioners, who treated patients with ASD. The questionnaire covered items on treatment methods, aims of treatment, KM syndrome differentiation, diagnostic tools, and sociodemographic characteristics. Frequency analysis was conducted to describe the participants and their practices.

Results

A total 22.4% KMDs (n = 57/255) completed the questionnaires and 54 KMDs (21.2%) matched the inclusion criteria. The KMDs utilized herbal medicine (27.3%), body acupuncture (17.6%), scalp acupuncture (10.7%), moxibustion (6.4%), and Korean medical psychotherapy (5.9%) to treat ASD. The most commonly prescribed herbal medicine was Yukmijihwang-tang. Forty-eight (88.9%) KMDs responded that they used KM syndrome differentiation. ‘Organ system, Qi, Blood, Yin, Yang, Fluid and Humor diagnosis’ was most frequently used for syndrome differentiation. ASD was mainly diagnosed based on the fourth edition of the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV) and DSM-5.

Conclusions

The present study demonstrated the current status of KMDs’ diagnosis and treatment of ASD. In future clinical trials and clinical practice guidelines, these findings will provide meaningful information on the actual practice patterns of KMDs.
Appendix
Available only for authorised users
Literature
1.
go back to reference American Psychiatric Association. Autism spectrum disorder. In: Diagnostic and statistical manual of mental disorders. 5th ed. Seoul: Hakjisa; 2013. p. 50–60.CrossRef American Psychiatric Association. Autism spectrum disorder. In: Diagnostic and statistical manual of mental disorders. 5th ed. Seoul: Hakjisa; 2013. p. 50–60.CrossRef
2.
go back to reference Christensen DL, Baio J, Braun KVN, Bilder D, Charles J, Constantino JN, Daniels J, Durkin MS, Fitzgerald RT, Margaret KS, Lee LC, Pettygrove S, Robinson C, Schulz E, Wells C, Wingate MS, Zahorodny W, Marshalyn YA. Prevalence and characteristics of autism spectrum disorder among children aged 8 years-autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR Surveill Summ. 2016;65(3):1–23.CrossRefPubMed Christensen DL, Baio J, Braun KVN, Bilder D, Charles J, Constantino JN, Daniels J, Durkin MS, Fitzgerald RT, Margaret KS, Lee LC, Pettygrove S, Robinson C, Schulz E, Wells C, Wingate MS, Zahorodny W, Marshalyn YA. Prevalence and characteristics of autism spectrum disorder among children aged 8 years-autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR Surveill Summ. 2016;65(3):1–23.CrossRefPubMed
3.
go back to reference Kim YS, Leventhal BL, Koh Y, Fombonne E, Laska E, Lim E, Cheon K, Kim S, Kim YK, Lee H, Song D, Grinker RR. Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry. 2011;168:904–12.CrossRefPubMed Kim YS, Leventhal BL, Koh Y, Fombonne E, Laska E, Lim E, Cheon K, Kim S, Kim YK, Lee H, Song D, Grinker RR. Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry. 2011;168:904–12.CrossRefPubMed
4.
go back to reference Myers SM, Johnson CP. Management of children with autism spectrum disorders. Pediatrics. 2007;120:1162–82.CrossRefPubMed Myers SM, Johnson CP. Management of children with autism spectrum disorders. Pediatrics. 2007;120:1162–82.CrossRefPubMed
7.
go back to reference Shin Y, Shin JS, Lee J, Lee YJ, Kim M, Ahn Y, Park KB, Shin BC, Lee MS, Kim JH, Cho JH, Ha IHA. Survey among Korea medicine doctors (KMDs) in Korea on patterns of integrative Korean medicine practice for lumbar intervertebral disc displacement: preliminary research for clinical practice guidelines. BMC Complement Altern Med. 2015;15:432.CrossRefPubMedPubMedCentral Shin Y, Shin JS, Lee J, Lee YJ, Kim M, Ahn Y, Park KB, Shin BC, Lee MS, Kim JH, Cho JH, Ha IHA. Survey among Korea medicine doctors (KMDs) in Korea on patterns of integrative Korean medicine practice for lumbar intervertebral disc displacement: preliminary research for clinical practice guidelines. BMC Complement Altern Med. 2015;15:432.CrossRefPubMedPubMedCentral
8.
go back to reference Oh IH, Yoon SJ, Park M, An S. Disease-specific differences in the use of traditional Korean medicine in Korea. BMC Complement Alternat Med. 2015;15:41.CrossRef Oh IH, Yoon SJ, Park M, An S. Disease-specific differences in the use of traditional Korean medicine in Korea. BMC Complement Alternat Med. 2015;15:41.CrossRef
11.
go back to reference Cheong M, Park J, Seo K, Huang J, Kim E, Kim J, Han K, Kim S, Kim Y. National survey on the use of Korean medicine and Korean herbal medicine. Korea Health Ind Dev Inst. 2014;11-1352000-000547-12:1–778. Cheong M, Park J, Seo K, Huang J, Kim E, Kim J, Han K, Kim S, Kim Y. National survey on the use of Korean medicine and Korean herbal medicine. Korea Health Ind Dev Inst. 2014;11-1352000-000547-12:1–778.
12.
go back to reference Institute of Medicine (US) Committee to Advise the Public Health Service on Clinical Practice Guidelines. Clinical practice guidelines: directions for a new program. Washington (DC): National Academies Press (US); 1990. Institute of Medicine (US) Committee to Advise the Public Health Service on Clinical Practice Guidelines. Clinical practice guidelines: directions for a new program. Washington (DC): National Academies Press (US); 1990.
13.
go back to reference Lee JN, Kim DG, Lee JY. Report on seven cases on patients with autism spectrum disorder treated by Kwakhyangjungkisanhapyukmijihwangtang-gamibang. J Pediatr Korean Med. 2015;29(1):50–9.CrossRef Lee JN, Kim DG, Lee JY. Report on seven cases on patients with autism spectrum disorder treated by Kwakhyangjungkisanhapyukmijihwangtang-gamibang. J Pediatr Korean Med. 2015;29(1):50–9.CrossRef
14.
go back to reference Jang JH, Lim YW, Lee SY. Two cases report about atypical autistic children. J Pediatr Korean Med. 2005;19(2):85–97. Jang JH, Lim YW, Lee SY. Two cases report about atypical autistic children. J Pediatr Korean Med. 2005;19(2):85–97.
18.
go back to reference Korean Society of Oriental Neuropsychiatry. Oriental neuropsychiatry. Seoul: Jip Moon Dang; 2010. Korean Society of Oriental Neuropsychiatry. Oriental neuropsychiatry. Seoul: Jip Moon Dang; 2010.
19.
go back to reference Kim KB, Kim DG, Kim YH, Kim JH, Min SY, Park EJ, Baek JH, Sung HK, Yu SA, Lee SY, Lee JY, Lee HJ, Chang GT, Jeong MJ, Chai JW, Cheon JH, Han YJ, Han JK. Korean pediatrics & adolescent medicine. Ui Sung Dang: Seoul; 2015. Kim KB, Kim DG, Kim YH, Kim JH, Min SY, Park EJ, Baek JH, Sung HK, Yu SA, Lee SY, Lee JY, Lee HJ, Chang GT, Jeong MJ, Chai JW, Cheon JH, Han YJ, Han JK. Korean pediatrics & adolescent medicine. Ui Sung Dang: Seoul; 2015.
20.
go back to reference Lavelle TA, Weinstein MC, Newhouse JP, Munir K, Kuhlthau KA, Prosser LA. Economic burden of childhood autism spectrum disorders. Pediatrics. 2014;133:e520–9.CrossRefPubMed Lavelle TA, Weinstein MC, Newhouse JP, Munir K, Kuhlthau KA, Prosser LA. Economic burden of childhood autism spectrum disorders. Pediatrics. 2014;133:e520–9.CrossRefPubMed
21.
go back to reference Buescher AVS, Cidav Z, Knapp M, Mandell DS. Costs of autism spectrum disorders in the United Kingdom and the United States. JAMA Pediatr. 2014;168(8):721–8.CrossRefPubMed Buescher AVS, Cidav Z, Knapp M, Mandell DS. Costs of autism spectrum disorders in the United Kingdom and the United States. JAMA Pediatr. 2014;168(8):721–8.CrossRefPubMed
22.
go back to reference Hyman SL, Levy SE. Autistic spectrum disorders: when traditional medicine is not enough. Contemp Pediatr. 2000;17(10):101. Hyman SL, Levy SE. Autistic spectrum disorders: when traditional medicine is not enough. Contemp Pediatr. 2000;17(10):101.
23.
go back to reference Sandler AD, Brazdziunas D, Cooley WC, Gonzalez de Pijem L, Hirsch D, Kastner TA, Kummer ME, Quint RD, Ruppert ES. Counseling families who choose complementary and alternative medicine for their child with chronic illness or disability. Pediatrics. 2001;107(3):598–601. Sandler AD, Brazdziunas D, Cooley WC, Gonzalez de Pijem L, Hirsch D, Kastner TA, Kummer ME, Quint RD, Ruppert ES. Counseling families who choose complementary and alternative medicine for their child with chronic illness or disability. Pediatrics. 2001;107(3):598–601.
24.
go back to reference Levy SE, Mandell DS, Merhar S, Ittenbach RF, Pinto-Martin JA. Use of complementary and alternative medicine among children recently diagnosed with autistic spectrum disorder. J Dev Behav Pediatr. 2003;24(6):418–22.CrossRefPubMed Levy SE, Mandell DS, Merhar S, Ittenbach RF, Pinto-Martin JA. Use of complementary and alternative medicine among children recently diagnosed with autistic spectrum disorder. J Dev Behav Pediatr. 2003;24(6):418–22.CrossRefPubMed
25.
go back to reference Levy SE, Hyman SL. Alternative/complementary approaches to treatment of children with autistic spectrum disorders. Infants Young Child. 2002;14(3):33–42.CrossRef Levy SE, Hyman SL. Alternative/complementary approaches to treatment of children with autistic spectrum disorders. Infants Young Child. 2002;14(3):33–42.CrossRef
26.
go back to reference Nickel RE. Controversial therapies for young children with developmental disabilities. Infants Young Child. 1996;8(4):29–40.CrossRef Nickel RE. Controversial therapies for young children with developmental disabilities. Infants Young Child. 1996;8(4):29–40.CrossRef
27.
go back to reference Hong SJ, Choi KH, Song IS. A clinical report of scalp acupuncture effects on autistic children. J Pediatr Korean Med. 2009;23(3):133–42. Hong SJ, Choi KH, Song IS. A clinical report of scalp acupuncture effects on autistic children. J Pediatr Korean Med. 2009;23(3):133–42.
28.
go back to reference Lee JH, Han JK, Lee HL, Kim YH. Review of clinical studies for oriental treatment of autism in traditional chinese medicine. J Pediatr Korean Med. 2014;28(4):85–95.CrossRef Lee JH, Han JK, Lee HL, Kim YH. Review of clinical studies for oriental treatment of autism in traditional chinese medicine. J Pediatr Korean Med. 2014;28(4):85–95.CrossRef
29.
go back to reference Lee JN, Lee SH, Lee JY. Recent clinical research on effect of acupuncture for autism spectrum disorder. J Pediatr Korean Med. 2015;29(4):119–26.CrossRef Lee JN, Lee SH, Lee JY. Recent clinical research on effect of acupuncture for autism spectrum disorder. J Pediatr Korean Med. 2015;29(4):119–26.CrossRef
30.
go back to reference Lee EJ, Lee BR, Lee JH, Chang GT. A study on the recent trend of chief complaint of Korean pediatric and adolescent outpatients. J Pediatr Korean Med. 2016;30(1):45–58.CrossRef Lee EJ, Lee BR, Lee JH, Chang GT. A study on the recent trend of chief complaint of Korean pediatric and adolescent outpatients. J Pediatr Korean Med. 2016;30(1):45–58.CrossRef
31.
go back to reference Choi MH, Kim DG, Lee JY. A study of the chief complaint of pediatric outpatients in the Kyung Hee oriental medicine hospital. J Pediatr Korean Med. 2010;24(3):121–37. Choi MH, Kim DG, Lee JY. A study of the chief complaint of pediatric outpatients in the Kyung Hee oriental medicine hospital. J Pediatr Korean Med. 2010;24(3):121–37.
32.
go back to reference Yoon KH, Koh DJ, Kim DG. Research on the actual conditions of the outpatients who visited the pediatrics department in ○○ university oriental medicine hospital between 2005 and 2006. J Pediatr Korean Med. 2007;21(3):125–43. Yoon KH, Koh DJ, Kim DG. Research on the actual conditions of the outpatients who visited the pediatrics department in ○○ university oriental medicine hospital between 2005 and 2006. J Pediatr Korean Med. 2007;21(3):125–43.
33.
go back to reference Yun Y, Jung W, Kim H, Jang BH, Kim MH, Noh J, Ko SG, Choi I. Exploring syndrome differentiation using non-negative matrix factorization and cluster analysis in patients with atopic dermatitis. Comput Biol Med. 2017;87:70–6.CrossRefPubMed Yun Y, Jung W, Kim H, Jang BH, Kim MH, Noh J, Ko SG, Choi I. Exploring syndrome differentiation using non-negative matrix factorization and cluster analysis in patients with atopic dermatitis. Comput Biol Med. 2017;87:70–6.CrossRefPubMed
35.
go back to reference Rho S, Kang M, Choi B, Sim D, Lee J, Lee E, Cho C, Oh J, Park S, Ko S, Shin M, Hong M, Bae H. Effects of Yukmijihwang-tang derivatives (YMJd), a memory enhancing herbal extract, on the gene-expression profile in the rat hippocampus. Biol Pharm Bull. 2005;28(1):87–93.CrossRefPubMed Rho S, Kang M, Choi B, Sim D, Lee J, Lee E, Cho C, Oh J, Park S, Ko S, Shin M, Hong M, Bae H. Effects of Yukmijihwang-tang derivatives (YMJd), a memory enhancing herbal extract, on the gene-expression profile in the rat hippocampus. Biol Pharm Bull. 2005;28(1):87–93.CrossRefPubMed
36.
go back to reference Huang Y, Zhang H, Yang S, Qiao H, Zhou W, Zhang Y. Liuwei Dihuang decoction facilitates the induction of long-term potentiation (LTP) in senescence accelerated mouse/prone 8 (SAMP8) hippocampal slices by inhibiting voltage-dependent calcium channels (VDCCs) and promoting N-methyl-d-aspartate receptor (NMDA) receptors. J Ethnopharmacol. 2012;140:384–90.CrossRefPubMed Huang Y, Zhang H, Yang S, Qiao H, Zhou W, Zhang Y. Liuwei Dihuang decoction facilitates the induction of long-term potentiation (LTP) in senescence accelerated mouse/prone 8 (SAMP8) hippocampal slices by inhibiting voltage-dependent calcium channels (VDCCs) and promoting N-methyl-d-aspartate receptor (NMDA) receptors. J Ethnopharmacol. 2012;140:384–90.CrossRefPubMed
37.
go back to reference Perrin JM, Coury DL, Hyman SL, Cole L, Reynolds AM, Clemons T. Complementary and alternative medicine use in a large pediatric autism sample. Pediatrics. 2012;130(Suppl):77.CrossRef Perrin JM, Coury DL, Hyman SL, Cole L, Reynolds AM, Clemons T. Complementary and alternative medicine use in a large pediatric autism sample. Pediatrics. 2012;130(Suppl):77.CrossRef
38.
go back to reference Park B, Yun KJ, Jung J, You S, Lee JA, Choi J, Kang BK, Alraek T, Birch S, Lee MS. Conceptualization and utilization of blood stasis syndrome among doctors of Korean medicine: results of a web-based survey. Am J Transl Res. 2014;6(6):857–68.PubMedPubMedCentral Park B, Yun KJ, Jung J, You S, Lee JA, Choi J, Kang BK, Alraek T, Birch S, Lee MS. Conceptualization and utilization of blood stasis syndrome among doctors of Korean medicine: results of a web-based survey. Am J Transl Res. 2014;6(6):857–68.PubMedPubMedCentral
39.
go back to reference Ko M, Lee J, Yun K, You S, Lee M. Perception of pattern identification in traditional medicine: a survey of Korean medical practitioners. J Tradit Chin Med. 2014;34(3):369–72.CrossRefPubMed Ko M, Lee J, Yun K, You S, Lee M. Perception of pattern identification in traditional medicine: a survey of Korean medical practitioners. J Tradit Chin Med. 2014;34(3):369–72.CrossRefPubMed
41.
go back to reference Son CH, Yun YJ, Yu SA. The experts survey and in-depth interview on the Korean medicine treatments for the cerebral palsy children. J Pediatr Korean Med. 2016;30(4):66–76.CrossRef Son CH, Yun YJ, Yu SA. The experts survey and in-depth interview on the Korean medicine treatments for the cerebral palsy children. J Pediatr Korean Med. 2016;30(4):66–76.CrossRef
43.
go back to reference Lee B, Lee J, Cheon JH, Sung HK, Cho SH, Chang GT. Efficacy and safety of acupuncture for the treatment of children with autism spectrum disorder: a systematic review and meta-analysis. Evid Based Complement Alternat Med. 2018; https://doi.org/10.1155/2018/1057539. Lee B, Lee J, Cheon JH, Sung HK, Cho SH, Chang GT. Efficacy and safety of acupuncture for the treatment of children with autism spectrum disorder: a systematic review and meta-analysis. Evid Based Complement Alternat Med. 2018; https://​doi.​org/​10.​1155/​2018/​1057539.
Metadata
Title
A survey of Korean medicine doctors’ clinical practice patterns for autism spectrum disorder: preliminary research for clinical practice guidelines
Authors
Jihong Lee
Sun Haeng Lee
Boram Lee
In Jun Yang
Gyu Tae Chang
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Complementary Medicine and Therapies / Issue 1/2018
Electronic ISSN: 2662-7671
DOI
https://doi.org/10.1186/s12906-018-2162-4

Other articles of this Issue 1/2018

BMC Complementary Medicine and Therapies 1/2018 Go to the issue