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BMC Complementary Medicine and Therapies

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Open Access 01-12-2017 | Research article

Microscopic identification and in vitro activity of Agastache rugosa (Fisch. et Mey) from Xinjiang, China

Authors: Haiyan Gong, Shaoyu Li, Lijuan He, Rena Kasimu

Published in: BMC Complementary Medicine and Therapies | Issue 1/2017

Abstract

Background

Agastache rugosa is well-known as a common traditional Chinese medicine, which have relieving summer-heat, analgesic and antipyretic effects, have long been used as folkloristic remedy in the treatment of several infectious diseases, anti-inflammatory, and for its antibacterial properties. Considering the lack of available data on the morphology, anatomy and in vitro activity of A. rugosa, the goal of the present study was to carry out the microscopic identification of its aerial parts and in vitro activity research as a contribution to the quality control and reasonable utilization involving A. rugosa.

Methods

The present study was (a) to describe the microscopic identification with usual light and scanning electron microtechniques of A. rugosa, collected from Xinjiang Region; (b) based on previous research on the essential oil constituents among different parts of A. rugosa from Xinjiang by GC-MS method, to evaluate its antibacterial effect and cell viabilitity assay.

Results

The microscopic identification of botanical material showed some typical structure. The essential oils from the dried flower (EOF) and leaves (EOL) of A. rugosa were 0.29% and 0.57% (w/w), respectively. The in vitro antibacterial activities showed strong inhibition against S.aureus, E. coli of EOF; strong inhibition against E. coli of EOL. Based GC-MS analysis, the MTT assay showed a dose and time-dependent increase in damage for gastric cancer cell line SGC-7901.

Conclusions

The results of this work, based on an extensive analytical characterization of the EOF and EOL chemical composition, compared with other origins, showed A. rugosa possessed antibacterial and cytotoxicity properties activities, which need much additional work to open up new biomedical application of these components.

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Title: Microscopic identification and in vitro activity of Agastache rugosa (Fisch. et Mey) from Xinjiang, China
Authors: Haiyan Gong
Shaoyu Li
Lijuan He
Rena Kasimu
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: BMC Complementary Medicine and Therapies / Issue 1/2017
Electronic ISSN: 2662-7671
DOI: https://doi.org/10.1186/s12906-017-1605-7

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Microscopic identification and in vitro activity of Agastache rugosa (Fisch. et Mey) from Xinjiang, China

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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