Skip to main content
Top
Published in: BMC Women's Health 1/2019

Open Access 01-12-2019 | Tramadol | Research article

Experiences with pain of early medical abortion: qualitative results from Nepal, South Africa, and Vietnam

Authors: Daniel Grossman, Sarah Raifman, Tshegofatso Bessenaar, Lan Dung Duong, Anand Tamang, Monica V. Dragoman

Published in: BMC Women's Health | Issue 1/2019

Login to get access

Abstract

Background

Medical abortion (MA) has become an increasingly popular choice for women even where surgical abortion services are available. Pain is often cited by women as one of the worst aspects of the MA experience, yet we know little about women’s experience with pain management during the process, particularly in low resource settings. The aim of this study is to better understand women’s experiences of pain with MA and strategies for improving quality of care.

Methods

This qualitative study was conducted as part of a three-arm randomized, controlled trial in Nepal, Vietnam, and South Africa to investigate the effect of prophylactic pain management on pain during MA through 63 days’ gestation. We purposively sampled seven parous and seven nulliparous women with a range of reported maximum pain levels from each country, totaling 42 participants. Thematic content analysis focused on MA pain experiences and management of pain compared to menstruation, labor, and previous abortions.

Results

MA is relatively less painful compared to giving birth and relatively more painful than menstruation, based on four factors: pain intensity, duration, associated symptoms and side effects, and response to pain medications. We identified four types of pain trajectories: minimal overall pain, brief intense pain, intermittent pain, and constant pain. Compared to previous abortion experiences, MA pain was less extreme (but sometimes longer in duration), more private, and less frightening. There were no distinct trends in pain trajectories by treatment group, parity, or country. Methods of coping with pain in MA and menstruation are similar in each respective country context, and use of analgesics was relatively uncommon. The majority of respondents reported that counseling about pain management before the abortion and support during the abortion process helped ease their pain and emotional stress.

Conclusions

Pain management during MA is increasingly essential to ensuring quality abortion care in light of the growing proportion of abortions completed with medication around the world. Incorporating a discussion about pain expectations and pain management strategies into pre-MA counseling and providing access to information and support during the MA process could improve the quality of care and experiences of MA patients.

Trial registration

Australian New Zealand Clinical Trials Registry ACTRN12613000017​729, registered January 8, 2013.
Appendix
Available only for authorised users
Literature
1.
go back to reference World Health Organization, Department of Reproductive Health and Research. Safe abortion: technical and policy guidance for health systems. 2nd ed; 2012. World Health Organization, Department of Reproductive Health and Research. Safe abortion: technical and policy guidance for health systems. 2nd ed; 2012.
2.
go back to reference Berer M. Medical abortion: issues of choice and acceptability. Reprod Health Matters. 2005;13(26):25–34.CrossRef Berer M. Medical abortion: issues of choice and acceptability. Reprod Health Matters. 2005;13(26):25–34.CrossRef
3.
go back to reference Dao B, Blum J, Thieba B, Raghavan S, Ouedraego M, Lankoande J, Winikoff B. Is misoprostol a safe, effective and acceptable alternative to manual vacuum aspiration for postabortion care? Results from a randomised trial in Burkina Faso. West Africa BJOG. 2007;114(11):1368–75.PubMed Dao B, Blum J, Thieba B, Raghavan S, Ouedraego M, Lankoande J, Winikoff B. Is misoprostol a safe, effective and acceptable alternative to manual vacuum aspiration for postabortion care? Results from a randomised trial in Burkina Faso. West Africa BJOG. 2007;114(11):1368–75.PubMed
4.
go back to reference Loeber OE. Motivation and satisfaction with early medical vs. surgical abortion in the Netherlands. Reprod Health Matters. 2010;18(35):145–53.CrossRef Loeber OE. Motivation and satisfaction with early medical vs. surgical abortion in the Netherlands. Reprod Health Matters. 2010;18(35):145–53.CrossRef
5.
go back to reference Winikoff B. Acceptability of medical abortion in early pregnancy. Fam Plan Perspect. 1995;27(4):142–8 185.CrossRef Winikoff B. Acceptability of medical abortion in early pregnancy. Fam Plan Perspect. 1995;27(4):142–8 185.CrossRef
6.
go back to reference Woldetsadik MA, Sendekie TY, White MT, Zegeye DT. Client preferences and acceptability for medical abortion and MVA as early pregnancy termination method in Northwest Ethiopia. Reprod Health. 2011;8:19.CrossRef Woldetsadik MA, Sendekie TY, White MT, Zegeye DT. Client preferences and acceptability for medical abortion and MVA as early pregnancy termination method in Northwest Ethiopia. Reprod Health. 2011;8:19.CrossRef
7.
go back to reference Winikoff B, Ellertson C, Elul B, Sivin I. Acceptability and feasibility of early pregnancy termination by mifepristone-misoprostol. Results of a large multicenter trial in the United States. Mifepristone Clinical Trials Group. Arch Fam Med. 1998;7(4):360–6.CrossRef Winikoff B, Ellertson C, Elul B, Sivin I. Acceptability and feasibility of early pregnancy termination by mifepristone-misoprostol. Results of a large multicenter trial in the United States. Mifepristone Clinical Trials Group. Arch Fam Med. 1998;7(4):360–6.CrossRef
8.
go back to reference Taylor D, Postlethwaite D, Desai S, James EA, Calhoun AW, Sheehan K, Weitz TA. Multiple determinants of the abortion care experience: from the patient’s perspective. Am J Med Qual. 2013;28(6):510–8.CrossRef Taylor D, Postlethwaite D, Desai S, James EA, Calhoun AW, Sheehan K, Weitz TA. Multiple determinants of the abortion care experience: from the patient’s perspective. Am J Med Qual. 2013;28(6):510–8.CrossRef
9.
go back to reference The efficacy and tolerance of mifepristone and prostaglandin in termination of pregnancy of less than 63 days gestation; UK Multicentre Study--final results. Contraception. 1997;55(1):1–5. The efficacy and tolerance of mifepristone and prostaglandin in termination of pregnancy of less than 63 days gestation; UK Multicentre Study--final results. Contraception. 1997;55(1):1–5.
10.
go back to reference Fiala C, Swahn ML, Stephansson O, Gemzell-Danielsson K. The effect of non-steroidal anti-inflammatory drugs on medical abortion with mifepristone and misoprostol at 13-22 weeks gestation. Hum Reprod. 2005;20(11):3072–7.CrossRef Fiala C, Swahn ML, Stephansson O, Gemzell-Danielsson K. The effect of non-steroidal anti-inflammatory drugs on medical abortion with mifepristone and misoprostol at 13-22 weeks gestation. Hum Reprod. 2005;20(11):3072–7.CrossRef
11.
go back to reference Jackson E, Kapp N. Pain control in first-trimester and second-trimester medical termination of pregnancy: a systematic review. Contraception. 2011;83(2):116–26.CrossRef Jackson E, Kapp N. Pain control in first-trimester and second-trimester medical termination of pregnancy: a systematic review. Contraception. 2011;83(2):116–26.CrossRef
12.
go back to reference Wiebe E. Pain control in medical abortion. Int J Gynaecol Obstet. 2001;74(3):275–80.CrossRef Wiebe E. Pain control in medical abortion. Int J Gynaecol Obstet. 2001;74(3):275–80.CrossRef
13.
go back to reference Livshits AMR, David LB, Spira M, Moshe-Zahav A, Seidman DS. Ibuprofen and paracetamol for pain relief during medical abortion: a double-blind randomized controlled study. Fertil Steril. 2009;91(5):3.CrossRef Livshits AMR, David LB, Spira M, Moshe-Zahav A, Seidman DS. Ibuprofen and paracetamol for pain relief during medical abortion: a double-blind randomized controlled study. Fertil Steril. 2009;91(5):3.CrossRef
14.
go back to reference Friedlander EB, Soon R, Salcedo J, Davis J, Tschann M, Kaneshiro B. Prophylactic Pregabalin to decrease pain during medication abortion: a randomized controlled trial. Obstet Gynecol. 2018;132(3):612–8.CrossRef Friedlander EB, Soon R, Salcedo J, Davis J, Tschann M, Kaneshiro B. Prophylactic Pregabalin to decrease pain during medication abortion: a randomized controlled trial. Obstet Gynecol. 2018;132(3):612–8.CrossRef
15.
go back to reference Royal College of Obstetrians and Gyneaecologists (RCOG). The care of women requesting induced abortion (evidence-based clinical guideline no. 7). 3rd ed; 2011. Royal College of Obstetrians and Gyneaecologists (RCOG). The care of women requesting induced abortion (evidence-based clinical guideline no. 7). 3rd ed; 2011.
16.
go back to reference World Health Organization. Unsafe abortion: global and regional estimates of the incidence of unsafe abortion and associated mortality in 2008. 6th ed; 2011. p. 56. World Health Organization. Unsafe abortion: global and regional estimates of the incidence of unsafe abortion and associated mortality in 2008. 6th ed; 2011. p. 56.
17.
go back to reference Raymond EG, Weaver MA, Louie KS, Dean G, Porsch L, Lichtenberg ES, Ali R, Arnesen M. Prophylactic compared with therapeutic ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial. Obstet Gynecol. 2013;122(3):558–64.CrossRef Raymond EG, Weaver MA, Louie KS, Dean G, Porsch L, Lichtenberg ES, Ali R, Arnesen M. Prophylactic compared with therapeutic ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial. Obstet Gynecol. 2013;122(3):558–64.CrossRef
18.
go back to reference Avraham S, Gat I, Duvdevani NR, Haas J, Frenkel Y, Seidman DS. Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study. Fertil Steril. 2012;97(3):612–5.CrossRef Avraham S, Gat I, Duvdevani NR, Haas J, Frenkel Y, Seidman DS. Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study. Fertil Steril. 2012;97(3):612–5.CrossRef
19.
go back to reference Dragoman MV, Grossman D, Kapp N, Huong NM, Habib N, Dung DL, Tamang A. Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days’ gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. Reprod Health. 2016;13(1):132.CrossRef Dragoman MV, Grossman D, Kapp N, Huong NM, Habib N, Dung DL, Tamang A. Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days’ gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. Reprod Health. 2016;13(1):132.CrossRef
20.
go back to reference Suhonen S, Tikka M, Kivinen S, Kauppila T. Pain during medical abortion: predicting factors from gynecologic history and medical staff evaluation of severity. Contraception. 2011;83(4):357–61.CrossRef Suhonen S, Tikka M, Kivinen S, Kauppila T. Pain during medical abortion: predicting factors from gynecologic history and medical staff evaluation of severity. Contraception. 2011;83(4):357–61.CrossRef
21.
go back to reference Engel GL. The need for a new medical model: a challenge for biomedicine. Science. 1977;196(4286):129–36.CrossRef Engel GL. The need for a new medical model: a challenge for biomedicine. Science. 1977;196(4286):129–36.CrossRef
22.
go back to reference Nelson S, Conroy C, Logan D. The biopsychosocial model of pain in the context of pediatric burn injuries. Eur J Pain. 2019;23(3):421–34.CrossRef Nelson S, Conroy C, Logan D. The biopsychosocial model of pain in the context of pediatric burn injuries. Eur J Pain. 2019;23(3):421–34.CrossRef
23.
go back to reference Sharma M, Dhungel S, Niroula S, Karki M. Knowledge and acceptance of labour analgesia in pregnant women. J Nepal Health Res Counc. 2018;16(3):302–6.CrossRef Sharma M, Dhungel S, Niroula S, Karki M. Knowledge and acceptance of labour analgesia in pregnant women. J Nepal Health Res Counc. 2018;16(3):302–6.CrossRef
24.
go back to reference Namisango E, Allsop MJ, Powell RA, Friedrichsdorf SJ, Luyirika EBK, Kiyange F, et al. Investigation of the practices, legislation, supply chain, and regulation of opioids for clinical pain management in Southern Africa: a multi-sectoral, cross-national, mixed methods study. J Pain Symptom Manag. 2018;55(3):851–63.CrossRef Namisango E, Allsop MJ, Powell RA, Friedrichsdorf SJ, Luyirika EBK, Kiyange F, et al. Investigation of the practices, legislation, supply chain, and regulation of opioids for clinical pain management in Southern Africa: a multi-sectoral, cross-national, mixed methods study. J Pain Symptom Manag. 2018;55(3):851–63.CrossRef
25.
go back to reference Nabukenya MT, Kintu A, Wabule A, Muyingo MT, Kwizera A. Knowledge, attitudes and use of labour analgesia among women at a low-income country antenatal clinic. BMC Anesthesiol. 2015;15:98.CrossRef Nabukenya MT, Kintu A, Wabule A, Muyingo MT, Kwizera A. Knowledge, attitudes and use of labour analgesia among women at a low-income country antenatal clinic. BMC Anesthesiol. 2015;15:98.CrossRef
26.
go back to reference Belanger E, Melzack R, Lauzon P. Pain of first-trimester abortion: a study of psychosocial and medical predictors. Pain. 1989;36(3):339–50.CrossRef Belanger E, Melzack R, Lauzon P. Pain of first-trimester abortion: a study of psychosocial and medical predictors. Pain. 1989;36(3):339–50.CrossRef
27.
go back to reference Pud D, Amit A. Anxiety as a predictor of pain magnitude following termination of first-trimester pregnancy. Pain Med. 2005;6(2):143–8.CrossRef Pud D, Amit A. Anxiety as a predictor of pain magnitude following termination of first-trimester pregnancy. Pain Med. 2005;6(2):143–8.CrossRef
28.
go back to reference Singh RH, Ghanem KG, Burke AE, Nichols MD, Rogers K, Blumenthal PD. Predictors and perception of pain in women undergoing first trimester surgical abortion. Contraception. 2008;78(2):155–61.CrossRef Singh RH, Ghanem KG, Burke AE, Nichols MD, Rogers K, Blumenthal PD. Predictors and perception of pain in women undergoing first trimester surgical abortion. Contraception. 2008;78(2):155–61.CrossRef
29.
go back to reference Gonzales EA, Ledesma RJ, McAllister DJ, Perry SM, Dyer CA, Maye JP. Effects of guided imagery on postoperative outcomes in patients undergoing same-day surgical procedures: a randomized, single-blind study. AANA J. 2010;78(3):181–8.PubMed Gonzales EA, Ledesma RJ, McAllister DJ, Perry SM, Dyer CA, Maye JP. Effects of guided imagery on postoperative outcomes in patients undergoing same-day surgical procedures: a randomized, single-blind study. AANA J. 2010;78(3):181–8.PubMed
30.
go back to reference Guerrero JM, Castano PM, Schmidt EO, Rosario L, Westhoff CL. Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial. Contraception. 2012;86(2):157–62.CrossRef Guerrero JM, Castano PM, Schmidt EO, Rosario L, Westhoff CL. Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial. Contraception. 2012;86(2):157–62.CrossRef
31.
go back to reference Chor J, Hill B, Martins S, Mistretta S, Patel A, Gilliam M. Doula support during first-trimester surgical abortion: a randomized controlled trial. Am J Obstet Gynecol. 2015;212(1):45.CrossRef Chor J, Hill B, Martins S, Mistretta S, Patel A, Gilliam M. Doula support during first-trimester surgical abortion: a randomized controlled trial. Am J Obstet Gynecol. 2015;212(1):45.CrossRef
32.
go back to reference Chor J, Lyman P, Tusken M, Patel A, Gilliam M. Women's experiences with doula support during first-trimester surgical abortion: a qualitative study. Contraception. 2016;93(3):244–8.CrossRef Chor J, Lyman P, Tusken M, Patel A, Gilliam M. Women's experiences with doula support during first-trimester surgical abortion: a qualitative study. Contraception. 2016;93(3):244–8.CrossRef
33.
go back to reference Fiala C, Cameron S, Bombas T, Parachini M, Agostini A, Lertxundi R, Gemzell-Danielsson K. Pain management for up to 9 weeks medical abortion - an international survey among abortion providers. Eur J Obstet Gynecol Reprod Biol. 2018;225:181–4.CrossRef Fiala C, Cameron S, Bombas T, Parachini M, Agostini A, Lertxundi R, Gemzell-Danielsson K. Pain management for up to 9 weeks medical abortion - an international survey among abortion providers. Eur J Obstet Gynecol Reprod Biol. 2018;225:181–4.CrossRef
34.
go back to reference Atlas LY, Wager TD. How expectations shape pain. Neurosci Lett. 2012;520(2):140–8.CrossRef Atlas LY, Wager TD. How expectations shape pain. Neurosci Lett. 2012;520(2):140–8.CrossRef
36.
go back to reference Singh SRL, Sedgh G, Kwok L, Onda T. Abortion worldwide 2017: uneven progress and unequal access. New York: Guttmacher Institute; 2018. Singh SRL, Sedgh G, Kwok L, Onda T. Abortion worldwide 2017: uneven progress and unequal access. New York: Guttmacher Institute; 2018.
Metadata
Title
Experiences with pain of early medical abortion: qualitative results from Nepal, South Africa, and Vietnam
Authors
Daniel Grossman
Sarah Raifman
Tshegofatso Bessenaar
Lan Dung Duong
Anand Tamang
Monica V. Dragoman
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Tramadol
Published in
BMC Women's Health / Issue 1/2019
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-019-0816-0

Other articles of this Issue 1/2019

BMC Women's Health 1/2019 Go to the issue