Skip to main content
Top
Published in: BMC Palliative Care 1/2015

Open Access 01-12-2015 | Research article

Effect of hospice care on quality indicators of end-of-life care among patients with liver cancer: a national longitudinal population-based study in Taiwan 2000–2011

Authors: Yee-Hsin Kao, Jui-Kun Chiang

Published in: BMC Palliative Care | Issue 1/2015

Login to get access

Abstract

Background

Quality of near end-of-life (EOL) care is typically evaluated using six accepted quality indicators (QIs). Research has yet to evaluate the quality of EOL care for liver cancer patients in Taiwan. We evaluated the effect of hospice care on the quality of EOL care for patients with advanced liver cancer.

Methods

Using claims data obtained from the Taiwan National Health Insurance Research Database, we analyzed the QIs of EOL care for patients who died between 2000 and 2011. Logistic regression was performed to identify predictors for QIs of EOL care.

Results

A total of 3092 adult patients died of liver cancer during the study period. The patients were divided into those who received hospice care for a period longer than 1 month (long-H group), shorter than 1 month (short-H group), and not at all (non-H group). There was no significant difference in survival probability among the three groups (p = 0.212). Compared with the non-H group, the long- and short-H groups exhibited a significantly lower risk of being admitted to an intensive care unit (ICU) (odds ratios [ORs] = 0.25 and 0.26, respectively, p < 0.001) and requiring cardiopulmonary resuscitation (CPR) during the final month of life (ORs = 0.21 and 0.09, respectively, p < 0.001). Compared with the non-H group, the short-H group had a higher risk of more than one emergency room (ER) visit, and more than one hospital admission (OR = 1.97, p = 0.003; and OR = 1.56, p = 0.001, respectively), but the long-H group did not differed significantly from the non-H group on these measures.

Conclusions

Patients with liver cancer who received hospice care were less likely to be admitted to ICUs or require CPR compared with those who received no hospice care. A longer duration of hospice care was associated with reduced risks of more than one ER visit and more than one hospital admission. We conclude that EOL cancer care in Taiwan might be improved by implementing policies encouraging early hospice referral programs.
Appendix
Available only for authorised users
Literature
2.
go back to reference Ho TH, Barbera L, Saskin R, Lu H, Neville BA, Earle CC. Trends in the aggressiveness of end-of-life cancer care in the universal health care system of Ontario. Canada J Clin Oncol. 2011;29:1587–91.CrossRefPubMed Ho TH, Barbera L, Saskin R, Lu H, Neville BA, Earle CC. Trends in the aggressiveness of end-of-life cancer care in the universal health care system of Ontario. Canada J Clin Oncol. 2011;29:1587–91.CrossRefPubMed
3.
go back to reference Pavlík T, Májek O, Mužík J, Koptíková J, Slavíček L, Fínek J, et al. Estimating the number of colorectal cancer patients treated with anti-tumour therapy in 2015: the analysis of the Czech national cancer registry. BMC Public Health. 2012;12:117.CrossRefPubMedPubMedCentral Pavlík T, Májek O, Mužík J, Koptíková J, Slavíček L, Fínek J, et al. Estimating the number of colorectal cancer patients treated with anti-tumour therapy in 2015: the analysis of the Czech national cancer registry. BMC Public Health. 2012;12:117.CrossRefPubMedPubMedCentral
5.
go back to reference Earle CC, Neville BA, Landrum MB, Souza JM, Weeks JC, Block SD, et al. Evaluating claims-based indicators of the intensity of end-of-life cancer care. Int J Qual Health Care. 2005;17:505–9.CrossRefPubMed Earle CC, Neville BA, Landrum MB, Souza JM, Weeks JC, Block SD, et al. Evaluating claims-based indicators of the intensity of end-of-life cancer care. Int J Qual Health Care. 2005;17:505–9.CrossRefPubMed
6.
go back to reference Houttekier D, Cohen J, Surkyn J, Deliens L. Study of recent and future trends in place of death in Belgium using death certificate data: shift from hospitals to care homes. BMC Public Health. 2011;11:228.CrossRefPubMedPubMedCentral Houttekier D, Cohen J, Surkyn J, Deliens L. Study of recent and future trends in place of death in Belgium using death certificate data: shift from hospitals to care homes. BMC Public Health. 2011;11:228.CrossRefPubMedPubMedCentral
7.
go back to reference Earle CC, Landrum MB, Souza JM, Neville BA, Weeks JC, Ayanian JZ. Aggressiveness of cancer care near the end of life: is it a quality-of-care issue? J Clin Oncol. 2008;26:3860–6.CrossRefPubMedPubMedCentral Earle CC, Landrum MB, Souza JM, Neville BA, Weeks JC, Ayanian JZ. Aggressiveness of cancer care near the end of life: is it a quality-of-care issue? J Clin Oncol. 2008;26:3860–6.CrossRefPubMedPubMedCentral
8.
go back to reference Barbera L, Paszat L, Chartier C. Indicators of poor quality end-of-life cancer care in Ontario. J Palliat Care. 2006;22:12–7.PubMed Barbera L, Paszat L, Chartier C. Indicators of poor quality end-of-life cancer care in Ontario. J Palliat Care. 2006;22:12–7.PubMed
9.
go back to reference Tang ST, Wu SC, Hung YN, Huang EW, Chen JS, Liu TW. Trends in quality of end-of-life care for Taiwanese cancer patients who died in 2000–2006. Ann Oncol. 2009;20:343–8.CrossRefPubMed Tang ST, Wu SC, Hung YN, Huang EW, Chen JS, Liu TW. Trends in quality of end-of-life care for Taiwanese cancer patients who died in 2000–2006. Ann Oncol. 2009;20:343–8.CrossRefPubMed
10.
go back to reference Tang ST, Chen ML, Huang EW, Koong SL, Lin GL, Hsiao SC. Hospice utilization in Taiwan by cancer patients who died between 2000 and 2004. J Pain Symptom Manage. 2007;33:446–53.CrossRefPubMed Tang ST, Chen ML, Huang EW, Koong SL, Lin GL, Hsiao SC. Hospice utilization in Taiwan by cancer patients who died between 2000 and 2004. J Pain Symptom Manage. 2007;33:446–53.CrossRefPubMed
11.
go back to reference Lin WY, Chiu TY, Ho CT, Hsu HS, Liu CS, Chiu CF, et al. Hospice shared-care saved medical expenditure and reduced the likelihood of intensive medical utilization among advanced cancer patients in Taiwan-a nationwide survey. Support Care Cancer. 2014;22:1907–14.CrossRefPubMed Lin WY, Chiu TY, Ho CT, Hsu HS, Liu CS, Chiu CF, et al. Hospice shared-care saved medical expenditure and reduced the likelihood of intensive medical utilization among advanced cancer patients in Taiwan-a nationwide survey. Support Care Cancer. 2014;22:1907–14.CrossRefPubMed
12.
go back to reference Dudgeon DJ, Knott C, Eichholz M, Gerlach JL, Chapman C, Viola R, et al. Palliative Care Integration Project (PCIP) quality improvement strategy evaluation. J Pain Symptom Manage. 2008;35:573–82.CrossRefPubMed Dudgeon DJ, Knott C, Eichholz M, Gerlach JL, Chapman C, Viola R, et al. Palliative Care Integration Project (PCIP) quality improvement strategy evaluation. J Pain Symptom Manage. 2008;35:573–82.CrossRefPubMed
13.
go back to reference Obermeyer Z, Makar M, Abujaber S, Abujaber S, Dominici F, Block S, et al. Association between the Medicare hospice benefit and health care utilization and costs for patients with poor-prognosis cancer. JAMA. 2014;312:1888–96.CrossRefPubMedPubMedCentral Obermeyer Z, Makar M, Abujaber S, Abujaber S, Dominici F, Block S, et al. Association between the Medicare hospice benefit and health care utilization and costs for patients with poor-prognosis cancer. JAMA. 2014;312:1888–96.CrossRefPubMedPubMedCentral
14.
go back to reference Gonsalves WI, Tashi T, Krishnamurthy J, Davies T, Ortman S, Thota R, et al. Effect of palliative care services on the aggressiveness of end-of-life care in the Veteran's Affairs cancer population. J Palliat Med. 2011;14:1231–5.CrossRefPubMed Gonsalves WI, Tashi T, Krishnamurthy J, Davies T, Ortman S, Thota R, et al. Effect of palliative care services on the aggressiveness of end-of-life care in the Veteran's Affairs cancer population. J Palliat Med. 2011;14:1231–5.CrossRefPubMed
15.
go back to reference Saito AM, Landrum MB, Neville BA, Ayanian JZ, Weeks JC, Earle CC. Hospice care and survival among elderly patients with lung cancer. J Palliat Med. 2011;14:929–39.CrossRefPubMedPubMedCentral Saito AM, Landrum MB, Neville BA, Ayanian JZ, Weeks JC, Earle CC. Hospice care and survival among elderly patients with lung cancer. J Palliat Med. 2011;14:929–39.CrossRefPubMedPubMedCentral
16.
go back to reference Hu W, Yasui Y, White J, Winget M. Aggressiveness of end-of-life care for patients with colorectal cancer in Alberta, Canada: 2006–2009. J Pain Symptom Manage. 2014;47:231–44.CrossRefPubMed Hu W, Yasui Y, White J, Winget M. Aggressiveness of end-of-life care for patients with colorectal cancer in Alberta, Canada: 2006–2009. J Pain Symptom Manage. 2014;47:231–44.CrossRefPubMed
17.
go back to reference Grunfeld E, Lethbridge L, Dewar R, Lawson B, Paszat LF, Johnston G, et al. Towards using administrative databases to measure population-based indicators of quality of end-of-life care: testing the methodology. Palliat Med. 2006;20:769–77.CrossRefPubMedPubMedCentral Grunfeld E, Lethbridge L, Dewar R, Lawson B, Paszat LF, Johnston G, et al. Towards using administrative databases to measure population-based indicators of quality of end-of-life care: testing the methodology. Palliat Med. 2006;20:769–77.CrossRefPubMedPubMedCentral
19.
go back to reference Lin CC, Lai MS, Syu CY, Chang SC, Tseng FY. Accuracy of diabetes diagnosis in health insurance claims data in Taiwan. J Formos Med Assoc. 2005;104:157–63.PubMed Lin CC, Lai MS, Syu CY, Chang SC, Tseng FY. Accuracy of diabetes diagnosis in health insurance claims data in Taiwan. J Formos Med Assoc. 2005;104:157–63.PubMed
20.
go back to reference Yu KH, Kuo CF, Luo SF, See LC, Chou IJ, Chang HC, et al. Risk of end-stage renal disease associated with gout: a nationwide population study. Arthritis Res Ther. 2012;14:R83.CrossRefPubMedPubMedCentral Yu KH, Kuo CF, Luo SF, See LC, Chou IJ, Chang HC, et al. Risk of end-stage renal disease associated with gout: a nationwide population study. Arthritis Res Ther. 2012;14:R83.CrossRefPubMedPubMedCentral
21.
go back to reference Earle CC, Neville BA, Landrum MB, Ayanian JZ, Block SD, Weeks JC. Trends in the aggressiveness of cancer care near the end of life. J Clin Oncol. 2004;22:315–21.CrossRefPubMed Earle CC, Neville BA, Landrum MB, Ayanian JZ, Block SD, Weeks JC. Trends in the aggressiveness of cancer care near the end of life. J Clin Oncol. 2004;22:315–21.CrossRefPubMed
22.
go back to reference Barbera L, Paszat L, Qiu F. End-of-life care in lung cancer patients in Ontario: aggressiveness of care in the population and a description of hospital admissions. J Pain Symptom Manage. 2008;35:267–74.CrossRefPubMed Barbera L, Paszat L, Qiu F. End-of-life care in lung cancer patients in Ontario: aggressiveness of care in the population and a description of hospital admissions. J Pain Symptom Manage. 2008;35:267–74.CrossRefPubMed
23.
go back to reference Lee CC, Su YC, Ho HC, Hung SK, Lee MS, Chou P, et al. Risk of stroke in patients hospitalized for isolated vertigo: a four-year follow-up study. Stroke. 2011;42:48–52.CrossRefPubMed Lee CC, Su YC, Ho HC, Hung SK, Lee MS, Chou P, et al. Risk of stroke in patients hospitalized for isolated vertigo: a four-year follow-up study. Stroke. 2011;42:48–52.CrossRefPubMed
24.
go back to reference Chang CM, Huang KY, Hsu TW, Su YC, Yang WZ, Chen TC, et al. Multivariate analyses to assess the effects of surgeon and hospital volume on cancer survival rates: a nationwide population-based study in Taiwan. PLoS One. 2012;7:e40590.CrossRefPubMedPubMedCentral Chang CM, Huang KY, Hsu TW, Su YC, Yang WZ, Chen TC, et al. Multivariate analyses to assess the effects of surgeon and hospital volume on cancer survival rates: a nationwide population-based study in Taiwan. PLoS One. 2012;7:e40590.CrossRefPubMedPubMedCentral
25.
go back to reference Wang HM, Koong SL, Hsiao SC, Chen JS, Liu TW, Tang ST. Impact of availability of an inpatient hospice unit on the parent hospital's quality of palliative care for Taiwanese cancer decedents, 2001–2006. J Pain Symptom Manage. 2011;42:400–9.CrossRefPubMed Wang HM, Koong SL, Hsiao SC, Chen JS, Liu TW, Tang ST. Impact of availability of an inpatient hospice unit on the parent hospital's quality of palliative care for Taiwanese cancer decedents, 2001–2006. J Pain Symptom Manage. 2011;42:400–9.CrossRefPubMed
26.
go back to reference Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893–917.CrossRefPubMed Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893–917.CrossRefPubMed
28.
go back to reference Tsukioka G, Kakizaki S, Sohara N, Sato K, Takagi H, Arai H, et al. Hepatocellular carcinoma in extremely elderly patients: an analysis of clinical characteristics, prognosis and patient survival. World J Gastroenterol. 2006;12:48–53.CrossRefPubMedPubMedCentral Tsukioka G, Kakizaki S, Sohara N, Sato K, Takagi H, Arai H, et al. Hepatocellular carcinoma in extremely elderly patients: an analysis of clinical characteristics, prognosis and patient survival. World J Gastroenterol. 2006;12:48–53.CrossRefPubMedPubMedCentral
29.
go back to reference Kelley M, Demiris G, Nguyen H, Oliver DP, Wittenberg-Lyles E. Informal hospice caregiver pain management concerns: a qualitative study. Palliat Med. 2013;27:673–82.CrossRefPubMedPubMedCentral Kelley M, Demiris G, Nguyen H, Oliver DP, Wittenberg-Lyles E. Informal hospice caregiver pain management concerns: a qualitative study. Palliat Med. 2013;27:673–82.CrossRefPubMedPubMedCentral
30.
go back to reference Moir C, Roberts R, Martz K, Perry J, Tivis L. Communicating with patients and their families about palliative and end-of-life care: comfort and educational needs of nurses. Int J Palliat Nurs. 2015;21:109–12.CrossRefPubMedPubMedCentral Moir C, Roberts R, Martz K, Perry J, Tivis L. Communicating with patients and their families about palliative and end-of-life care: comfort and educational needs of nurses. Int J Palliat Nurs. 2015;21:109–12.CrossRefPubMedPubMedCentral
31.
go back to reference Hu WY, Chiu TY, Cheng YR, Chuang RB, Chen CY. Why Taiwanese hospice patients want to stay in hospital: health-care professionals' beliefs and solutions. Support Care Cancer. 2004;12:285–92.CrossRefPubMed Hu WY, Chiu TY, Cheng YR, Chuang RB, Chen CY. Why Taiwanese hospice patients want to stay in hospital: health-care professionals' beliefs and solutions. Support Care Cancer. 2004;12:285–92.CrossRefPubMed
32.
go back to reference Chambaere K, Rietjens JAC, Cohen J, Pardon K, Deschepper R, Pasman HRW, et al. Is educational attainment related to end-of-life decision-making? A large post-mortem survey in Belgium. BMC Public Health. 2013;13:1055. Chambaere K, Rietjens JAC, Cohen J, Pardon K, Deschepper R, Pasman HRW, et al. Is educational attainment related to end-of-life decision-making? A large post-mortem survey in Belgium. BMC Public Health. 2013;13:1055.
33.
go back to reference Cheng HW, Li CW, Chan KY, Ho R, Sham MK. Bringing palliative care into geriatrics in a Chinese culture society--results of a collaborative model between palliative medicine and geriatrics unit in Hong Kong. J Am Geriatr Soc. 2014;62:779–81.CrossRefPubMed Cheng HW, Li CW, Chan KY, Ho R, Sham MK. Bringing palliative care into geriatrics in a Chinese culture society--results of a collaborative model between palliative medicine and geriatrics unit in Hong Kong. J Am Geriatr Soc. 2014;62:779–81.CrossRefPubMed
34.
go back to reference Chan CL, Chow AY. Death, dying and bereavement: the Hong Kong Chinese experience. Hong Kong: Hong Kong University Press; 2006. Chan CL, Chow AY. Death, dying and bereavement: the Hong Kong Chinese experience. Hong Kong: Hong Kong University Press; 2006.
35.
go back to reference Tang ST. Meanings of dying at home for Chinese patients in Taiwan with terminal cancer: a literature review. Cancer Nurs. 2000;23:367–70.CrossRefPubMed Tang ST. Meanings of dying at home for Chinese patients in Taiwan with terminal cancer: a literature review. Cancer Nurs. 2000;23:367–70.CrossRefPubMed
36.
go back to reference Christakis NA, Iwashyna TJ. Impact of individual and market factors on the timing of initiation of hospice terminal care. Med Care. 2000;38:528–41.CrossRefPubMed Christakis NA, Iwashyna TJ. Impact of individual and market factors on the timing of initiation of hospice terminal care. Med Care. 2000;38:528–41.CrossRefPubMed
37.
go back to reference Teno JM, Shu JE, Casarett D, Spence C, Rhodes R, Connor S. Timing of referral to hospice and quality of care: length of stay and bereaved family members' perceptions of the timing of hospice referral. J Pain Symptom Manage. 2007;34:120–5.CrossRefPubMed Teno JM, Shu JE, Casarett D, Spence C, Rhodes R, Connor S. Timing of referral to hospice and quality of care: length of stay and bereaved family members' perceptions of the timing of hospice referral. J Pain Symptom Manage. 2007;34:120–5.CrossRefPubMed
38.
go back to reference Bradley EH, Prigerson H, Carlson MD, Cherlin E, Johnson-Hurzeler R, Kasl SV. Depression among surviving caregivers: does length of hospice enrollment matter? Am J Psychiatry. 2004;161:2257–62.CrossRefPubMed Bradley EH, Prigerson H, Carlson MD, Cherlin E, Johnson-Hurzeler R, Kasl SV. Depression among surviving caregivers: does length of hospice enrollment matter? Am J Psychiatry. 2004;161:2257–62.CrossRefPubMed
39.
go back to reference Schockett ER, Teno JM, Miller SC, Stuart B. Late referral to hospice and bereaved family member perception of quality of end-of-life care. J Pain Symptom Manage. 2005;30:400–7.CrossRefPubMed Schockett ER, Teno JM, Miller SC, Stuart B. Late referral to hospice and bereaved family member perception of quality of end-of-life care. J Pain Symptom Manage. 2005;30:400–7.CrossRefPubMed
40.
go back to reference Miller SC, Kinzbrunner B, Pettit P, Williams JR. How does the timing of hospice referral influence hospice care in the last days of life? J Am Geriatr Soc. 2003;51:798–806.CrossRefPubMed Miller SC, Kinzbrunner B, Pettit P, Williams JR. How does the timing of hospice referral influence hospice care in the last days of life? J Am Geriatr Soc. 2003;51:798–806.CrossRefPubMed
41.
go back to reference Yamagishi A, Morita T, Kawagoe S, Shimizu M, Ozawa T, An E, et al. Length of home hospice care, family-perceived timing of referrals, perceived quality of care, and quality of death and dying in terminally ill cancer patients who died at home. Support Care Cancer. 2015;23:491–9.CrossRefPubMed Yamagishi A, Morita T, Kawagoe S, Shimizu M, Ozawa T, An E, et al. Length of home hospice care, family-perceived timing of referrals, perceived quality of care, and quality of death and dying in terminally ill cancer patients who died at home. Support Care Cancer. 2015;23:491–9.CrossRefPubMed
42.
go back to reference The debate in hospice care. J Oncol Pract 2008 4: 153–7. The debate in hospice care. J Oncol Pract 2008 4: 153–7.
43.
go back to reference McGorty EK, Bornstein BH. Barriers to physicians' decisions to discuss hospice: insights gained from the United States hospice model. J Eval Clin Pract. 2003;9:363–72.CrossRefPubMed McGorty EK, Bornstein BH. Barriers to physicians' decisions to discuss hospice: insights gained from the United States hospice model. J Eval Clin Pract. 2003;9:363–72.CrossRefPubMed
44.
go back to reference Ogle KS, Mavis B, Wyatt GK. Physicians and hospice care: attitudes, knowledge, and referrals. J Palliat Med. 2002;5:85–92.CrossRefPubMed Ogle KS, Mavis B, Wyatt GK. Physicians and hospice care: attitudes, knowledge, and referrals. J Palliat Med. 2002;5:85–92.CrossRefPubMed
45.
go back to reference Brickner L, Scannell K, Marquet S, Ackerson L. Barriers to hospice care and referrals: survey of physicians' knowledge, attitudes, and perceptions in a health maintenance organization. J Palliat Med. 2004;7:411–8.CrossRefPubMed Brickner L, Scannell K, Marquet S, Ackerson L. Barriers to hospice care and referrals: survey of physicians' knowledge, attitudes, and perceptions in a health maintenance organization. J Palliat Med. 2004;7:411–8.CrossRefPubMed
46.
go back to reference Ngo-Metzger Q, August KJ, Srinivasan M, Liao S, Meyskens Jr FL. End-of-Life care: guidelines for patient-centered communication. Am Fam Physician. 2008;77:167–74.PubMed Ngo-Metzger Q, August KJ, Srinivasan M, Liao S, Meyskens Jr FL. End-of-Life care: guidelines for patient-centered communication. Am Fam Physician. 2008;77:167–74.PubMed
47.
go back to reference McCarthy EP, Burns RB, Davis RB, Phillips RS. Barriers to hospice care among older patients dying with lung and colorectal cancer. J Clin Oncol. 2003;21:728–35.CrossRefPubMed McCarthy EP, Burns RB, Davis RB, Phillips RS. Barriers to hospice care among older patients dying with lung and colorectal cancer. J Clin Oncol. 2003;21:728–35.CrossRefPubMed
48.
go back to reference Glare P, Virik K, Jones M, Hudson M, Eychmuller S, Malcolm H, et al. A systematic review of physicians' survival predictions in terminally ill cancer patients. BMJ. 2003;327:195–8. Glare P, Virik K, Jones M, Hudson M, Eychmuller S, Malcolm H, et al. A systematic review of physicians' survival predictions in terminally ill cancer patients. BMJ. 2003;327:195–8.
49.
go back to reference Hui D, Kilgore K, Nguyen L, Hall S, Fajardo J, Tonye P, et al. The accuracy of probabilistic versus temporal clinician prediction of survival for patients with advanced cancer: a preliminary report. Oncologist. 2011;16:1642–8.CrossRefPubMedPubMedCentral Hui D, Kilgore K, Nguyen L, Hall S, Fajardo J, Tonye P, et al. The accuracy of probabilistic versus temporal clinician prediction of survival for patients with advanced cancer: a preliminary report. Oncologist. 2011;16:1642–8.CrossRefPubMedPubMedCentral
Metadata
Title
Effect of hospice care on quality indicators of end-of-life care among patients with liver cancer: a national longitudinal population-based study in Taiwan 2000–2011
Authors
Yee-Hsin Kao
Jui-Kun Chiang
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Palliative Care / Issue 1/2015
Electronic ISSN: 1472-684X
DOI
https://doi.org/10.1186/s12904-015-0036-9

Other articles of this Issue 1/2015

BMC Palliative Care 1/2015 Go to the issue