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Open Access 01-12-2022 | Granulomatous Disorder | Research article

Non-infectious granulomatous disorders of the upper lip: clinicopathological analysis of 11 patients

Authors: Irene Lafuente-Ibáñez de Mendoza, Emmanuelle Vigarios, Béatrice Herbault-Barres, Javier Alberdi-Navarro, Vincent Sibaud, Delphine Maret, José Manuel Aguirre-Urizar

Published in: BMC Oral Health | Issue 1/2022

Abstract

Background

Non-infectious granulomatous disorders of the upper lip represent a special chapter of oral and maxillofacial pathology. In this work we report a case-series of this process, to analyse its main clinicopathological features and find differential data that allow us improve its diagnosis and understand its pathogenesis.

Methods

We present 11 cases of non-infectious granulomatous disorders of the upper lip, 8 women and 3 men with an age range of 29–84 years, who have been attended at the Oral Medicine Department of the IUCT (France) and the Oral Medicine Unit of the UPV/EHU (Spain). All clinicopathological data were collected in a specific protocol.

Results

We recognized 4 different subtypes of non-infectious granulomatous disorders of the upper lip: (1) associated with Crohn’s disease (1 case), (2) associated with foreign body (2 cases), (3) associated with gingivitis lichenoid-like (4 cases), (4) idiopathic (4 cases).

Conclusions

Clinicopathological differences were identified between these subtypes. A good differential diagnosis is necessary in all cases to rule out the presence of local or systemic etiopathogenic factors.

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Title: Non-infectious granulomatous disorders of the upper lip: clinicopathological analysis of 11 patients
Authors: Irene Lafuente-Ibáñez de Mendoza
Emmanuelle Vigarios
Béatrice Herbault-Barres
Javier Alberdi-Navarro
Vincent Sibaud
Delphine Maret
José Manuel Aguirre-Urizar
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Granulomatous Disorder
Crohn's Disease
Published in: BMC Oral Health / Issue 1/2022
Electronic ISSN: 1472-6831
DOI: https://doi.org/10.1186/s12903-022-02189-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Non-infectious granulomatous disorders of the upper lip: clinicopathological analysis of 11 patients

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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