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BMC Oral Health
Published in: BMC Oral Health 1/2018

Open Access 01-12-2018 | Research article

Influence of povidone-iodine on micro-tensile bonding strength to dentin under simulated pulpal pressure

Authors: Najlaa M. Alamoudi, Alaa M. Baik, Azza A. El-Housseiny, Tariq S. Abu Haimed, Ahmed S. Bakry

Published in: BMC Oral Health | Issue 1/2018

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Abstract

Background

Previous studies had reported that bond strength deteriorate over time following the dentin surface pretreatment with chlorhexidine. Therefore, further investigations are needed to evaluate the effect of other materials such as povidone iodine.
The purpose of this study was to investigate the effects of 10% povidone-iodine pretreatment on the resin-dentin micro-tensile bond strength of a single bond adhesive system in permanent teeth over time, and compare it with 2% chlorhexidine.

Methods

Flat dentin surfaces were prepared in 63 extracted permanent teeth. Teeth were randomly assigned to a 10% povidone-iodine pretreatment, a 2% chlorhexidine pretreatment, or a control group. Composite resin blocks were built up over treated surfaces under pulp pressure simulation. The prepared specimens were assigned to three storage time, 24 h, 1 week, and 2 months. Samples were vertically sectioned to obtain specimens of 0.7 to 1.2 mm2 cross-sectional area.

Results

No significant reduction of bond strength of povidone iodine group was found among the three storage times (p = 0.477). A significant reduction of bond strength for both chlorhexidine and control groups was found in the three storage times (p <  0.001).

Conclusion

Povidone iodine pretreatment of etched dentin was effective in reducing the loss of bond strength over time, while the chlorhexidine pretreatment and negative control showed significant deterioration in micro-tensile bond strength over time in permanent teeth.
Literature
1.
Hashimoto M, Ohno H, Kaga M, Endo K, Sano H, Oguchi H. In vivo degradation of resin-dentin bonds in humans over 1 to 3 years. J Dent Res. 2000;79:1385–91.CrossRef
2.
Pashley DH, Tay FR, Yiu C, Hashimoto M, Breschi L, Carvalho RM, et al. Collagen degradation by host-derived enzymes during aging. J Dent Res. 2004;83:216–21.CrossRef
3.
Palosaari H, Pennington CJ, Larmas M, Edwards DR, Tjäderhane L, Salo T. Expression profile of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue. Eur J Oral Sci. 2003;111:117–27.CrossRef
4.
Tjäderhane L, Larjava H, Sorsa T, Uitto VJ, Larmas M, Salo T. The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions. J Dent Res. 1998;77:1622–9.CrossRef
5.
Breschi L, Mazzoni A, Nato F, Carrilho M, Visintini E, Tjäderhane L, et al. Chlorhexidine stabilizes the adhesive interface: a 2-year in vitro study. Dent Mater. 2010;26:320–5.CrossRef
6.
Siggia S. The chemistry of polyvinylpyrrolidone-iodine. J Am Pharm Assoc Am Pharm Assoc. 1957;46:201–4.CrossRef
7.
Shelanski HA, Shelanski MV. PVP-iodine: history, toxicity and therapeutic uses. J Int Coll Surg. 1956;25:727–34.PubMed
8.
Wormser U, Brodsky B, Reich R. Topical treatment with povidone iodine reduces nitrogen mustard-induced skin collagenolytic activity. Arch Toxicol. 2002;76:119–21.CrossRef
9.
Shi L, Ermis R, Kiedaisch B, Carson D. The effect of various wound dressings on the activity of debriding enzymes. Adv Skin Wound Care. 2010;23:456–62.CrossRef
10.
Sadek FT, Braga RR, Muench A, Liu Y, Pashley DH, Tay FR. Ethanol wet-bonding challenges current anti-degradation strategy. J Dent Res. 2010;89:1499–504.CrossRef
11.
Pashley DH, Tay FR, Imazato S. How to increase the durability of resin-dentin bonds. Compend Contin Educ Dent. 2011;32:60–4.PubMed
12.
De Munck J, Van Meerbeek B, Yoshida Y, Inoue S, Vargas M, Suzuki K, et al. Four-year water degradation of total-etch adhesives bonded to dentin. J Dent Res. 2003;82:136–40.CrossRef
13.
Gernhardt CR, Schaller HG, Kielbassa AM. The influence of human plasma used for dentin perfusion on tensile bond strength of different light-curing materials. Am J Dent. 2005;18:318–22.PubMed
14.
Moll K, Haller B. Effect of intrinsic and extrinsic moisture on bond strength to dentine. J Oral Rehabil. 2000;27:150–65.CrossRef
15.
Moll K, Park HJ, Haller B. Effect of simulated pulpal pressure on dentin bond strength of self-etching bonding systems. Am J Dent. 2005;18:335–9.PubMed
16.
Ciucchi B, Bouillaguet S, Holz J, Pashley D. Dentinal fluid dynamics in human teeth, in vivo. J Endod. 1995;21:191–4.CrossRef
17.
Vongsavan N, Matthews B. Fluid flow through cat dentine in vivo. Arch Oral Biol. 1992;37:175–85.CrossRef
18.
Abu Nawareg M, Elkassas D, Zidan A, Abuelenain D, Abu Haimed T, Hassan AH, et al. Is chlorhexidine-methacrylate as effective as chlorhexidine digluconate in preserving resin dentin interfaces? J Dent. 2016;45:7–13.CrossRef
19.
Vuotila T, Ylikontiola L, Sorsa T, Luoto H, Hanemaaijer R, Salo T, et al. The relationship between MMPs and pH in whole saliva of radiated head and neck cancer patients. J Oral Pathol Med. 2002;31:329–38.CrossRef
20.
Perote LC, Kamozaki MB, Gutierrez NC, Tay FR, Pucci CR. Effect of matrix metalloproteinase-inhibiting solutions and aging methods on dentin bond strength. J Adhes Dent. 2015;17:347–52.PubMed
21.
Carrilho MR, Carvalho RM, Sousa EN, Nicolau J, Breschi L, Mazzoni A, et al. Substantivity of chlorhexidine to human dentin. Dent Mater. 2010;26:779–85.CrossRef
22.
Durani P, Leaper D. Povidone-iodine: use in hand disinfection, skin preparation and antiseptic irrigation. Int Wound J. 2008;5:376–87.CrossRef
23.
Stadelmann WK, Digenis AG, Tobin GR. Impediments to wound healing. Am J Surg. 1998;176:39S–47S.CrossRef
24.
Quirynen M, Teughels W, De Soete M, van Steenberghe D. Topical antiseptics and antibiotics in the initial therapy of chronic adult periodontitis: microbiological aspects. Periodontol 2000. 2002;28:72–90.CrossRef
25.
Thomas GW, Rael LT, Bar-Or R, Shimonkevitz R, Mains CW, Slone DS, et al. Mechanisms of delayed wound healing by commonly used antiseptics. J Trauma. 2009;66:82–90.CrossRef
26.
Pallasch TJ, Slots J. Antibiotic prophylaxis and the medically compromised patient. Periodontol 2000. 1996;10:107–38.CrossRef
27.
Demir A, Malkoc S, Sengun A, Koyuturk AE, Sener Y. Effects of chlorhexidine and povidone-iodine mouth rinses on the bond strength of an orthodontic composite. Angle Orthod. 2005;75:392–6.PubMed
28.
Breschi L, Cammelli F, Visintini E, Mazzoni A, Vita F, Carrilho M, et al. Influence of chlorhexidine concentration on the durability of etch-and-rinse dentin bonds: a 12-month in vitro study. J Adhes Dent. 2009;11:191–8.PubMedPubMedCentral
29.
Perdigao J, Denehy GE, Swift EJ Jr. Effects of chlorhexidine on dentin surfaces and shear bond strengths. Am J Dent. 1994;7:81–4.PubMed
30.
Meiers JC, Shook LW. Effect of disinfectants on the bond strength of composite to dentin. Am J Dent. 1996;9:11–4.PubMed
31.
de Castro FL, de Andrade MF, Duarte Junior SL, Vaz LG, Ahid FJ. Effect of 2% chlorhexidine on microtensile bond strength of composite to dentin. J Adhes Dent. 2003;5:129–38.PubMed
32.
Pappas M, Burns DR, Moon PC, Coffey JP. Influence of a 3-step tooth disinfection procedure on dentin bond strength. J Prosthet Dent. 2005;93:545–50.CrossRef
33.
Carrilho MR, Carvalho RM, de Goes MF, di Hipolito V, Geraldeli S, Tay FR, et al. Chlorhexidine preserves dentin bond in vitro. J Dent Res. 2007;86:90–4.CrossRef
34.
Carrilho MR, Geraldeli S, Tay F, de Goes MF, Carvalho RM, Tjäderhane L, et al. In vivo preservation of the hybrid layer by chlorhexidine. J Dent Res. 2007;86:529–33.CrossRef
35.
Montagner AF, Sarkis-Onofre R, Pereira-Cenci T, Cenci MS. MMP inhibitors on dentin stability: a systematic review and meta-analysis. J Dent Res. 2014;93:733–43.CrossRef
36.
Campos EA, Correr GM, Leonardi DP, Barato-Filho F, Gonzaga CC, Zielak JC. Chlorhexidine diminishes the loss of bond strength over time under simulated pulpal pressure and thermo-mechanical stressing. J Dent. 2009;37:108–14.CrossRef
37.
Yuan Y, Shimada Y, Ichinose S, Tagami J. Qualitative analysis of adhesive interface nanoleakage using FE-SEM/EDS. Dent Mater. 2007;23:561–9.CrossRef
Metadata
Title
Influence of povidone-iodine on micro-tensile bonding strength to dentin under simulated pulpal pressure
Authors
Najlaa M. Alamoudi
Alaa M. Baik
Azza A. El-Housseiny
Tariq S. Abu Haimed
Ahmed S. Bakry
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Oral Health / Issue 1/2018
Electronic ISSN: 1472-6831
DOI
https://doi.org/10.1186/s12903-018-0645-9

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