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Published in: BMC Endocrine Disorders 1/2020

01-12-2020 | Obesity | Research article

Are there really any predictive factors for a successful weight loss after bariatric surgery?

Authors: Diego Cadena-Obando, Claudia Ramírez-Rentería, Aldo Ferreira-Hermosillo, Alejandra Albarrán-Sanchez, Ernesto Sosa-Eroza, Mario Molina-Ayala, Etual Espinosa-Cárdenas

Published in: BMC Endocrine Disorders | Issue 1/2020

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Abstract

Background

Currently, bariatric surgery is the most effective treatment for severe obesity and its metabolic complications; however, 15–35% of the patients that undergo bariatric surgery do not reach their goal for weight loss. The aim of this study was to determine the proportion of patients that didn’t reach the goal of an excess weight loss of 50% or more during the first 12 months and determine the factors associated to this failure.

Methods

We obtained the demographic, anthropometric and biochemical information from 130 patients with severe obesity who underwent bariatric surgery in our institution between 2012 and 2017. We used self-reports of physical activity, caloric intake and diet composition. An unsuccessful weight loss was considered when the patient lost < 50% or more of the excess weight 12 months after surgery. We compared the characteristics between the successful and unsuccessful groups in order to find the factors associated with success.

Results

We included 130 patients (mean age 48 ± 9 years, 81.5% were women). One year after surgery, 26 (20%) had loss < 50% EBW. Unsuccessful surgery was associated with an older age, previous history of hypertension, abdominal surgery or depression/anxiety, also the number of comorbidities and unemployment affected the results. These patients loss enough weight to improve some of their comorbidities, but they are more prone to regain weight 2 years after surgery.

Conclusions

A fifth of the patients undergoing bariatric surgery may not lose enough weight to be considered successful by current standards. Some patients may benefit from the surgery in the short term, but they are more likely to regain weight after 2 years. The factors influencing this result are still controversial but may be population-specific. Early detection of the patients that are more likely to fail is imperative to establish additional therapeutic strategies, without denying them the opportunity of surgery or waiting for weight re-gain to occur.
Literature
1.
go back to reference Hernández M. Encuesta Nacional de Salud y Nutrición de Medio Camino 2016. Inst Nac Salud Pública. 2016;1:1–154. Hernández M. Encuesta Nacional de Salud y Nutrición de Medio Camino 2016. Inst Nac Salud Pública. 2016;1:1–154.
2.
go back to reference Whitlock G, Lwington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al. Body-mass index and cause-specifi c mortality in 900 000 adults : collaborative analyses of 57 prospective. Lancet. 2009;373(9669):1083–96.CrossRef Whitlock G, Lwington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al. Body-mass index and cause-specifi c mortality in 900 000 adults : collaborative analyses of 57 prospective. Lancet. 2009;373(9669):1083–96.CrossRef
3.
go back to reference Maggard MA, Shugarman LR, Suttorp M, Maglione M, Sugerman HJ, Livingstone EH, Nguyen NT, Liz Z, Mojica WA, Hilton L, Rhodes S, Morton SC, Shekelle PG. Meta-analysis: surgical treatment of obesity. Ann Intern Med. 2005;142(7):547–59.CrossRef Maggard MA, Shugarman LR, Suttorp M, Maglione M, Sugerman HJ, Livingstone EH, Nguyen NT, Liz Z, Mojica WA, Hilton L, Rhodes S, Morton SC, Shekelle PG. Meta-analysis: surgical treatment of obesity. Ann Intern Med. 2005;142(7):547–59.CrossRef
4.
go back to reference Brolin RE, Cody RP. Adding malabsorption for weight loss failure after gastric bypass. Surg Endosc. 2007;21(11):1924–6.CrossRef Brolin RE, Cody RP. Adding malabsorption for weight loss failure after gastric bypass. Surg Endosc. 2007;21(11):1924–6.CrossRef
5.
go back to reference Rawlins ML, Teel D, Hedgcorth K, Maguire JP. Revision of roux-en-Y gastric bypass to distal bypass for failed weight loss. Surg Obes Relat Dis. 2011;7(1):45–9.CrossRef Rawlins ML, Teel D, Hedgcorth K, Maguire JP. Revision of roux-en-Y gastric bypass to distal bypass for failed weight loss. Surg Obes Relat Dis. 2011;7(1):45–9.CrossRef
6.
go back to reference Parikh M, Pomp A, Gagner M. Laparoscopic conversion of failed gastric bypass to duodenal switch: technical considerations and preliminary outcomes. Surg Obes Relat Dis. 2007;3(6):611–8.CrossRef Parikh M, Pomp A, Gagner M. Laparoscopic conversion of failed gastric bypass to duodenal switch: technical considerations and preliminary outcomes. Surg Obes Relat Dis. 2007;3(6):611–8.CrossRef
7.
go back to reference Al-Khyatt W, Ryall R, Leeder P, Ahmed J, Awad S. Predictors of inadequate weight loss after laparoscopic gastric bypass for morbid obesity. Obes Surg. 2017;27(6):1446–52.CrossRef Al-Khyatt W, Ryall R, Leeder P, Ahmed J, Awad S. Predictors of inadequate weight loss after laparoscopic gastric bypass for morbid obesity. Obes Surg. 2017;27(6):1446–52.CrossRef
8.
go back to reference Barhouch AS, Padoin AV, Casagrande DS, Chatkin R, Süssenbach SP, Pufal MA, et al. Predictors of excess weight loss in obese patients after gastric bypass: a 60-month follow-up. Obes Surg. 2016;26(6):1178–85.CrossRef Barhouch AS, Padoin AV, Casagrande DS, Chatkin R, Süssenbach SP, Pufal MA, et al. Predictors of excess weight loss in obese patients after gastric bypass: a 60-month follow-up. Obes Surg. 2016;26(6):1178–85.CrossRef
9.
go back to reference Cazzo E, Da Silva FP, Pareja JC, Chaim EA. Predictors for weight loss failure following roux-en-Y gastric bypass. Arq Gastroenterol. 2014;51(4):328–30.CrossRef Cazzo E, Da Silva FP, Pareja JC, Chaim EA. Predictors for weight loss failure following roux-en-Y gastric bypass. Arq Gastroenterol. 2014;51(4):328–30.CrossRef
10.
go back to reference Livhits M, Mercado C, Yermilov I, Parikh JA, Dutson E, Mehran A, et al. Preoperative predictors of weight loss following bariatric surgery: systematic review. Obes Surg. 2012;22(1):70–89.CrossRef Livhits M, Mercado C, Yermilov I, Parikh JA, Dutson E, Mehran A, et al. Preoperative predictors of weight loss following bariatric surgery: systematic review. Obes Surg. 2012;22(1):70–89.CrossRef
11.
go back to reference Giraldo Villa A, Serna López ÁM, Mustiola Calleja KG, López Gómez LM, Donado Gómez J, Toro Escobar JM. Factors related with weight loss in a cohort of obese patients after gastric bypass. Nutr Hosp. 2013;28(3):623–30.PubMed Giraldo Villa A, Serna López ÁM, Mustiola Calleja KG, López Gómez LM, Donado Gómez J, Toro Escobar JM. Factors related with weight loss in a cohort of obese patients after gastric bypass. Nutr Hosp. 2013;28(3):623–30.PubMed
12.
go back to reference Chevallier JM, Paita M, Rodde-Dunet MH, Marty M, Nogues F, Slim K, et al. Predictive factors of outcome after gastric banding: a nationwide survey on the role of center activity and patients’ behavior. Ann Surg. 2007;246(6):1034–9.CrossRef Chevallier JM, Paita M, Rodde-Dunet MH, Marty M, Nogues F, Slim K, et al. Predictive factors of outcome after gastric banding: a nationwide survey on the role of center activity and patients’ behavior. Ann Surg. 2007;246(6):1034–9.CrossRef
13.
go back to reference Sheets CS, Peat CM, Berg KC, White EK, Bocchieri-Ricciardi L, Chen EY, et al. Post-operative psychosocial predictors of outcome in bariatric surgery. Obes Surg. 2015;25(2):330–45.CrossRef Sheets CS, Peat CM, Berg KC, White EK, Bocchieri-Ricciardi L, Chen EY, et al. Post-operative psychosocial predictors of outcome in bariatric surgery. Obes Surg. 2015;25(2):330–45.CrossRef
14.
go back to reference Contreras JE, Santander C, Court I, Bravo J. Correlation between age and weight loss after bariatric surgery. Obes Surg. 2013;23(8):1286–9.CrossRef Contreras JE, Santander C, Court I, Bravo J. Correlation between age and weight loss after bariatric surgery. Obes Surg. 2013;23(8):1286–9.CrossRef
15.
go back to reference Manini TM. Mobility decline in old age: a time to intervene. Exerc Sport Sci Rev. 2013;41(1):2.CrossRef Manini TM. Mobility decline in old age: a time to intervene. Exerc Sport Sci Rev. 2013;41(1):2.CrossRef
16.
go back to reference Scozzari G, Passera R, Benvenga R, Toppino M, Morino M. Age as a long-term prognostic factor in bariatric surgery. Ann Surg. 2012;256(5):724–8.CrossRef Scozzari G, Passera R, Benvenga R, Toppino M, Morino M. Age as a long-term prognostic factor in bariatric surgery. Ann Surg. 2012;256(5):724–8.CrossRef
17.
go back to reference Toth MJ, Tchernof A. Lipid metabolism in the elderly. Eur J Clin Nutr. 2000;54(Suppl 3):S121–5.CrossRef Toth MJ, Tchernof A. Lipid metabolism in the elderly. Eur J Clin Nutr. 2000;54(Suppl 3):S121–5.CrossRef
18.
go back to reference Hughes A, Kumari M. Unemployment, underweight, and obesity: findings from understanding society (UKHLS). Prev Med (Baltim). 2017;97:19–25.CrossRef Hughes A, Kumari M. Unemployment, underweight, and obesity: findings from understanding society (UKHLS). Prev Med (Baltim). 2017;97:19–25.CrossRef
19.
go back to reference Ali SM, Lindström M. Socioeconomic, psychosocial, behavioural, and psychological determinants of BMI among young women: differing patterns for underweight and overweight/obesity. Eur J Pub Health. 2006;16(3):325–31.CrossRef Ali SM, Lindström M. Socioeconomic, psychosocial, behavioural, and psychological determinants of BMI among young women: differing patterns for underweight and overweight/obesity. Eur J Pub Health. 2006;16(3):325–31.CrossRef
20.
go back to reference Campos GM, Rabl C, Mulligan K, Posselt A, Rogers SJ, Westphalen AC, et al. Factors associated with weight loss after gastric bypass. Arch Surg. 2008;143(9):877–83.CrossRef Campos GM, Rabl C, Mulligan K, Posselt A, Rogers SJ, Westphalen AC, et al. Factors associated with weight loss after gastric bypass. Arch Surg. 2008;143(9):877–83.CrossRef
21.
go back to reference Fox B, Chen E, Suzo A, Jolles S, Greenberg JA, Campos GM, et al. Dietary and psych predictors of weight loss after gastric bypass. J Surg Res. 2015;197(2):283–90.CrossRef Fox B, Chen E, Suzo A, Jolles S, Greenberg JA, Campos GM, et al. Dietary and psych predictors of weight loss after gastric bypass. J Surg Res. 2015;197(2):283–90.CrossRef
22.
go back to reference Júnior WS, Do Amaral JL, Nonino-Borges CB. Factors related to weight loss up to 4 years after bariatric surgery. Obes Surg. 2011;21(11):1724–30.CrossRef Júnior WS, Do Amaral JL, Nonino-Borges CB. Factors related to weight loss up to 4 years after bariatric surgery. Obes Surg. 2011;21(11):1724–30.CrossRef
23.
go back to reference Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 2002;346(21):1623–30.CrossRef Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 2002;346(21):1623–30.CrossRef
24.
go back to reference Ionut V, Burch M, Youdim A, Bergman RN. Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity. 2013;21(6):1093–103.CrossRef Ionut V, Burch M, Youdim A, Bergman RN. Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity. 2013;21(6):1093–103.CrossRef
25.
go back to reference Robinson AH, Adler S, Stevens HB, Darcy AM, Morton JM, Safer DL. What variables are associated with successful weight loss outcomes for bariatric surgery after 1 year? Surg Obes Relat Dis. 2014;10(4):697–704.CrossRef Robinson AH, Adler S, Stevens HB, Darcy AM, Morton JM, Safer DL. What variables are associated with successful weight loss outcomes for bariatric surgery after 1 year? Surg Obes Relat Dis. 2014;10(4):697–704.CrossRef
26.
go back to reference Bergh I, Lundin Kvalem I, Risstad H, Sniehotta FF. Preoperative predictors of adherence to dietary and physical activity recommendations and weight loss one year after surgery. Surg Obes Relat Dis. 2016;12(4):910–8.CrossRef Bergh I, Lundin Kvalem I, Risstad H, Sniehotta FF. Preoperative predictors of adherence to dietary and physical activity recommendations and weight loss one year after surgery. Surg Obes Relat Dis. 2016;12(4):910–8.CrossRef
27.
go back to reference Subar AF, Freedman LS, Tooze JA, Kirkpatrick SI, Boushey C, Neuhouser ML, et al. Addressing current criticism regarding the value of self-report dietary data. J Nutr. 2015;145:2639–45.CrossRef Subar AF, Freedman LS, Tooze JA, Kirkpatrick SI, Boushey C, Neuhouser ML, et al. Addressing current criticism regarding the value of self-report dietary data. J Nutr. 2015;145:2639–45.CrossRef
28.
go back to reference Freedman LS, Commins JM, Moler JE, Arab L, Baer DJ, Kipnis V, et al. Pooled results from 5 validation studies of dietary self-report instruments using recovery biomarkers for energy and protein intake. Am J Epidemiol. 2014;180:172–88.CrossRef Freedman LS, Commins JM, Moler JE, Arab L, Baer DJ, Kipnis V, et al. Pooled results from 5 validation studies of dietary self-report instruments using recovery biomarkers for energy and protein intake. Am J Epidemiol. 2014;180:172–88.CrossRef
Metadata
Title
Are there really any predictive factors for a successful weight loss after bariatric surgery?
Authors
Diego Cadena-Obando
Claudia Ramírez-Rentería
Aldo Ferreira-Hermosillo
Alejandra Albarrán-Sanchez
Ernesto Sosa-Eroza
Mario Molina-Ayala
Etual Espinosa-Cárdenas
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Endocrine Disorders / Issue 1/2020
Electronic ISSN: 1472-6823
DOI
https://doi.org/10.1186/s12902-020-0499-4

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