Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
BMC Urology
Published in: BMC Urology 1/2020

01-12-2020 | Nephrectomy | Case report

Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review

Authors: Xiaobo Ding, Gang Wang, Tiejun Wang, Xiaobo Ma, Yanbo Wang

Published in: BMC Urology | Issue 1/2020

Login to get access

Abstract

Background

Xanthogranulomatous pyelonephritis (XGP) is an uncommon form of chronic pyelonephritis. Most patients of XGP are diffuse in radiology and the clinical features are typical.

Case presentation

We present a case of 24-year-old female with the absence of symptoms and normal laboratory examinations. Contrast computed tomography and intravenous pyelography demonstrate infiltrative renal mass and renal cell carcinoma is presumed. Laparoscopic right radical nephrectomy is performed, but the final pathological result shows XGP.

Conclusions

As far as we know, this is the first case report of XGP without any symptoms/signs and with normal laboratory examinations. The diagnosis of atypical XGP is challenging and preoperative renal mass biopsy should be considered in special cases.
Literature
1.
Li L, Parwani AV. Xanthogranulomatous pyelonephritis. Arch Pathol Lab Med. 2011;135(5):671–4.PubMed
2.
Sangüesa Nebot C, Picó Aliaga S, Serrano Durbá A, Roca MJ. Xantogranulomatous pyeloneprhritis in children. Insights Imaging. 2018;9(5):643–51.CrossRef
3.
Ayad A, Ettouhami B, Thami B, Bentahila A. Abdominal mass revealing xanthogranulomatous pyelonephritis in an infant. Pan Afr Med J. 2017;27:17.PubMedPubMedCentral
4.
Stoica I, O'Kelly F, McDermott MB, Quinn FMJ. Xanthogranulomatous pyelonephritis in a paediatric cohort (1963–2016): Outcomes from a large single-center series. J Pediatr Urol. 2018;14(2):169.e1–7.CrossRef
5.
Çaliskan S, Özsoy E, Kaba S, Koca O, Öztürk MI. Xanthogranulomatous pyelonephritis. Arch Iran Med. 2016;19(10):712–4.PubMed
6.
Schlagenhaufer F. Uber eigentumliche staphylomykosen der nieren und des pararenalen bindewebes. Frankf Z Pathol. 1916;19:139–48.
7.
Bingöl-Koloğlu M, Ciftçi AO, Senocak ME, Tanyel FC, Karnak I, Büyükpamukçu N. Xanthogranulomatous pyelonephritis in children: diagnostic and therapeutic aspects. Eur J Pediatr Surg. 2002;12(1):42–8.CrossRef
8.
Schlagenhaufer F. Uber epigentumliche Staphylmykosen der Nieven und der pararenalen Bindegewebes. Frankfurt Z Pathol. 1916:139–48..
9.
Siddappa S, Ramprasad K, Muddegowda MK. Xanthogranulomatous pyelonephritis: a retrospective review of 16 cases. Korean J Urol. 2011;52(6):421–4.CrossRef
10.
Rao AG, Eberts PT. Xanthogranulomatous pyelonephritis: an uncommon pediatric renal mass. Pediatr Radiol. 2011;41(5):671–2.CrossRef
11.
Shah K, Parikh M, Pal B, Modi P. Bilateral focal xanthogranulomatous pyelonephritis in a child presenting as complex cystic renal mass: a report on non-surgical treatment. Eur J Pediatr Surg. 2011;21(3):207–8.CrossRef
12.
Hyla-Klekot L, Paradysz A, Kucharska G, Lipka K, Zajecki W. Successfully treated bilateral xanthogranulomatous pyelonephritis in a child. Pediatr Nephrol. 2008;23(10):1895–6.CrossRef
13.
Chlif M, Chakroun M, Ben Rhouma S, Ben Chehida MA, Sellami A, Gargouri MM, Nouira Y. Xanthogranulomatous pyelonephritis presenting as a pseudotumour. Can Urol Assoc J. 2016;10(1–2):E36–40.CrossRef
14.
Shah K, Parikh M, Gharia P, Modi PR. Xanthogranulomatous pyelonephritis-mimicking renal mass in 5-month-old child. Urology. 2012;79(6):1360–2.CrossRef
15.
Hendrickson RJ, Lutfiyya WL, Karrer FM, Furness PD 3rd, Mengshol S, Bensard DD. Xanthogranulomatous pyelonephritis. J Pediatr Surg. 2006;41(2):e15–7.CrossRef
16.
Posielski NM, Bui A, Wells SA, Best SL, Gettle LM, Ziemlewicz TJ, Lubner MG, Hinshaw JL, Lee FT Jr, Allen GO, Nakada SY, Abel EJ. Risk factors for complications and nondiagnostic results following 1,155 consecutive percutaneous Core renal mass biopsies. J Urol. 2019;201(6):1080–7.CrossRef
17.
Fitouri Z, Nouira Y, Nouira K, Sallami S, Hmidi M, El Fekih N, Horchani A. Focal xanthogranulomatous pyelonephritis: success of conservative treatment. A case report. Tunis Med. 2008;86(10):912–5.PubMed
18.
Ho CI, Wen YK, Chen ML. Xanthogranulomatous pyelonephritis successfully treated with antibiotics only. J Chin Med Assoc. 2008;71(12):643–5.CrossRef
19.
Herrera-Caceres JO, Finelli A, Jewett MAS. Renal tumor biopsy: indicators, technique, safety, accuracy results, and impact on treatment decision management. World J Urol. 2019;37(3):437–43.
20.
Campbell S, Uzzo RG, Allaf ME, Bass EB, Cadeddu JA, Chang A, Clark PE, Davis BJ, Derweesh IH, Giambarresi L, Gervais DA, Hu SL, Lane BR, Leibovich BC, Pierorazio PM. Renal mass and localized renal Cancer: AUA guideline. J Urol. 2017;198(3):520–9.CrossRef
Metadata
Title
Atypical focal xanthogranulomatous pyelonephritis without clinical symptoms presenting as infiltrative renal cancer: a case report and literature review
Authors
Xiaobo Ding
Gang Wang
Tiejun Wang
Xiaobo Ma
Yanbo Wang
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2020
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/s12894-020-00632-3

Other articles of this Issue 1/2020

BMC Urology 1/2020 Go to the issue

Research article

Prevalence of microhematuria in renal colic and urolithiasis: a systematic review and meta-analysis

Research article

Contrast-enhanced transrectal ultrasound can reduce collection of unnecessary biopsies when diagnosing prostate cancer and is predictive of biochemical recurrence following a radical prostatectomy in patients with localized prostate cancer

Case report

The use of hyperbaric oxygen to treat actinic rectal fistula after SpaceOAR use and radiotherapy for prostate cancer: a case report

Research article

Quality of life among patients with multiple sclerosis and voiding dysfunction: a cross-sectional study

Research article

Efficacy and safety of transurethral split of prostate for benign prostatic hyperplasia: a meta-analysis

Case report

Transurethral resection of a bladder trigone leiomyoma: a rare case report