Skip to main content
Top
Published in: BMC Urology 1/2020

01-12-2020 | Research article

Comparative analysis of retrograde intrarenal surgery and modified ultra-mini percutaneous nephrolithotomy in management of lower pole renal stones (1.5–3.5 cm)

Authors: Zhuohang Li, Cong Lai, Arvind K. Shah, Weibin Xie, Cheng Liu, Li Huang, Kuiqing Li, Hao Yu, Kewei Xu

Published in: BMC Urology | Issue 1/2020

Login to get access

Abstract

Background

To compare the safety and efficacy of retrograde intrarenal surgery (RIRS) and modified Ultra-mini percutaneous nephrolithotomy (UMP) in semi-supine combined lithotomy position for the management of 1.5–3.5 cm lower pole renal stones (LPSs).

Methods

A total of 63 patients with 1.5–3.5 cm LPSs who underwent RIRS (n = 33) or modified UMP (n = 30) in diameter between January 2017 and January 2019 were analyzed retrospectively. Modified UMP was performed in semi-supine combined lithotomy position and a 9.5/11.5 F ureteral access sheath (UAS) was inserted during the procedure in order to maintain low pelvic pressure and to facilitate the removal of stone fragments. Base-line parameters, stone characteristics, illness condition, operation time, postoperative hemoglobin (Hb) drop, postoperative creatinine (Cr) elevation, length of hospital stay, length of postoperative hospital stay, stone-free rate (SFR) and complications were compared between the two groups.

Results

There were no significant differences between the two groups in base-line parameters, stone characteristics and illness condition. The mean operating time of RIRS group was longer than UMP group (95.61 ± 21.9 vs. 55.0 ± 16.1 min, p < 0.001). The mean postoperative Hb drop was less in RIRS group (7.42 ± 4.7 vs. 15.70 ± 9.8 g/L, p < 0.001). The length of hospital stay and postoperative hospital stay for RIRS were shorter than UMP (4.76 ± 1.1 vs. 5.83 ± 0.8 d, p < 0.001, 2.97 ± 0.9 vs. 4.07 ± 0.9 d, p < 0.001). The Early SFR was higher in UMP group (54.5 vs. 80.0%, p < 0.050) while SFR at 1-month and 3-months postoperatively was similar in both groups (p = 0.504, p = 0.675). There were no significant differences between the two groups in complications (p = 0.228).

Conclusion

For patients with 1.5–3.5 cm LPSs, both modified UMP and RIRS are safe and viable. The modified UMP technique was used in this study, application semi-supine combined lithotomy position and the retention of UAS can improve the surgical efficiency and maintain low pressure perfusion in the kidney, which resulted in superior treatment efficacy. Therefore, we highly recommend this technique for LPSs with heavy stone burdens.
Literature
1.
go back to reference Donaldson JF, Lardas M, Scrimgeour D, Stewart F, MacLennan S, Lam TB, McClinton S. Systematic review and meta-analysis of the clinical effectiveness of shock wave lithotripsy, retrograde intrarenal surgery, and percutaneous nephrolithotomy for lower-pole renal stones. Eur Urol. 2015;67:612–6.CrossRef Donaldson JF, Lardas M, Scrimgeour D, Stewart F, MacLennan S, Lam TB, McClinton S. Systematic review and meta-analysis of the clinical effectiveness of shock wave lithotripsy, retrograde intrarenal surgery, and percutaneous nephrolithotomy for lower-pole renal stones. Eur Urol. 2015;67:612–6.CrossRef
2.
go back to reference Fan J, Zhang T, Zhu W, Gurioli A, Ketegwe IR, Zeng G. The role of super-mini percutaneous nephrolithotomy (SMP) in the treatment of symptomatic lower pole renal stones (LPSs) after the failure of shockwave lithotripsy (SWL) or retrograde intrarenal surgery (RIRS). Urolithiasis. 2019;47:297–301.CrossRef Fan J, Zhang T, Zhu W, Gurioli A, Ketegwe IR, Zeng G. The role of super-mini percutaneous nephrolithotomy (SMP) in the treatment of symptomatic lower pole renal stones (LPSs) after the failure of shockwave lithotripsy (SWL) or retrograde intrarenal surgery (RIRS). Urolithiasis. 2019;47:297–301.CrossRef
3.
go back to reference Palmero JL, Duran-Rivera AJ, Miralles J, Pastor JC, Benedicto A. Comparative study for the efficacy and safety of percutaneous nefhrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) for the treatment of 2-3,5 cm kidney stones. Arch Esp Urol. 2016;69:67–72.PubMed Palmero JL, Duran-Rivera AJ, Miralles J, Pastor JC, Benedicto A. Comparative study for the efficacy and safety of percutaneous nefhrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) for the treatment of 2-3,5 cm kidney stones. Arch Esp Urol. 2016;69:67–72.PubMed
4.
go back to reference Jung GH, Jung JH, Ahn TS, Lee JS, Cho SY, Jeong CW, Lee SB, Kim HH, Oh SJ. Comparison of retrograde intrarenal surgery versus a single-session percutaneous nephrolithotomy for lower-pole stones with a diameter of 15 to 30 mm: a propensity score-matching study. Korean J Urol. 2015;56:525–32.CrossRef Jung GH, Jung JH, Ahn TS, Lee JS, Cho SY, Jeong CW, Lee SB, Kim HH, Oh SJ. Comparison of retrograde intrarenal surgery versus a single-session percutaneous nephrolithotomy for lower-pole stones with a diameter of 15 to 30 mm: a propensity score-matching study. Korean J Urol. 2015;56:525–32.CrossRef
5.
go back to reference Jones P, Elmussareh M, Aboumarzouk OM, Mucksavage P, Somani BK. Role of minimally invasive (micro and ultra-mini) PCNL for adult urinary stone disease in the modern era: evidence from a systematic review. Curr Urol Rep. 2018;19:27.CrossRef Jones P, Elmussareh M, Aboumarzouk OM, Mucksavage P, Somani BK. Role of minimally invasive (micro and ultra-mini) PCNL for adult urinary stone disease in the modern era: evidence from a systematic review. Curr Urol Rep. 2018;19:27.CrossRef
6.
go back to reference Schoofs F, Celentano G, Abboudi H, Choong S, Iselin C, Wirth G. Evolution and miniaturization of percutaneous nephrolithotomy. Rev Med Suisse. 2019;15:2198–201.PubMed Schoofs F, Celentano G, Abboudi H, Choong S, Iselin C, Wirth G. Evolution and miniaturization of percutaneous nephrolithotomy. Rev Med Suisse. 2019;15:2198–201.PubMed
7.
go back to reference Pai A, Wai HA, Ali M, Theaker M, Watson G, Mackie S. Outcomes of retrograde intrarenal surgery compared with ultra-mini percutaneous nephrolithotomy in the management of renal calculi. Cent European J Urol. 2019;72:169–73.PubMedPubMedCentral Pai A, Wai HA, Ali M, Theaker M, Watson G, Mackie S. Outcomes of retrograde intrarenal surgery compared with ultra-mini percutaneous nephrolithotomy in the management of renal calculi. Cent European J Urol. 2019;72:169–73.PubMedPubMedCentral
8.
go back to reference Li MM, Yang HM, Liu XM, Qi HG, Weng GB. Retrograde intrarenal surgery vs miniaturized percutaneous nephrolithotomy to treat lower pole renal stones 1.5–2.5 cm in diameter. World J Clin Cases. 2018;6:931–5.CrossRef Li MM, Yang HM, Liu XM, Qi HG, Weng GB. Retrograde intrarenal surgery vs miniaturized percutaneous nephrolithotomy to treat lower pole renal stones 1.5–2.5 cm in diameter. World J Clin Cases. 2018;6:931–5.CrossRef
9.
go back to reference Desai J, Solanki R. Ultra-mini percutaneous nephrolithotomy (UMP): one more armamentarium. BJU Int. 2013;112:1046–9.PubMed Desai J, Solanki R. Ultra-mini percutaneous nephrolithotomy (UMP): one more armamentarium. BJU Int. 2013;112:1046–9.PubMed
10.
go back to reference Desai J, Zeng G, Zhao Z, Zhong W, Chen W, Wu W. A novel technique of ultra-mini-percutaneous nephrolithotomy: introduction and an initial experience for treatment of upper urinary calculi less than 2 cm. Biomed Res Int. 2013;2013:490793.CrossRef Desai J, Zeng G, Zhao Z, Zhong W, Chen W, Wu W. A novel technique of ultra-mini-percutaneous nephrolithotomy: introduction and an initial experience for treatment of upper urinary calculi less than 2 cm. Biomed Res Int. 2013;2013:490793.CrossRef
11.
go back to reference Shah AK, Xu K, Liu H, Huang H, Lin T, Bi L, Jinli H, Fan X, Shrestha R, Huang J. Implementation of Ultramini percutaneous Nephrolithotomy for treatment of 2-3 cm kidney stones: a preliminary report. J Endourol. 2015;29:1231–6.CrossRef Shah AK, Xu K, Liu H, Huang H, Lin T, Bi L, Jinli H, Fan X, Shrestha R, Huang J. Implementation of Ultramini percutaneous Nephrolithotomy for treatment of 2-3 cm kidney stones: a preliminary report. J Endourol. 2015;29:1231–6.CrossRef
12.
go back to reference Schoenthaler M, Wilhelm K, Hein S, Adams F, Schlager D, Wetterauer U, Hawizy A, Bourdoumis A, Desai J, Miernik A. Ultra-mini PCNL versus flexible ureteroscopy: a matched analysis of treatment costs (endoscopes and disposables) in patients with renal stones 10-20 mm. World J Urol. 2015;33:1601–5.CrossRef Schoenthaler M, Wilhelm K, Hein S, Adams F, Schlager D, Wetterauer U, Hawizy A, Bourdoumis A, Desai J, Miernik A. Ultra-mini PCNL versus flexible ureteroscopy: a matched analysis of treatment costs (endoscopes and disposables) in patients with renal stones 10-20 mm. World J Urol. 2015;33:1601–5.CrossRef
13.
go back to reference Zhang H, Hong TY, Li G, Jiang N, Hu C, Cui X, Chu C, Zhao JL. Comparison of the efficacy of ultra-mini PCNL, flexible Ureteroscopy, and shock wave lithotripsy on the treatment of 1-2 cm lower pole renal calculi. Urol Int. 2019;102:153–9.CrossRef Zhang H, Hong TY, Li G, Jiang N, Hu C, Cui X, Chu C, Zhao JL. Comparison of the efficacy of ultra-mini PCNL, flexible Ureteroscopy, and shock wave lithotripsy on the treatment of 1-2 cm lower pole renal calculi. Urol Int. 2019;102:153–9.CrossRef
14.
go back to reference Wilhelm K, Hein S, Adams F, Schlager D, Miernik A, Schoenthaler M. Ultra-mini PCNL versus flexible ureteroscopy: a matched analysis of analgesic consumption and treatment-related patient satisfaction in patients with renal stones 10-35 mm. World J Urol. 2015;33:2131–6.CrossRef Wilhelm K, Hein S, Adams F, Schlager D, Miernik A, Schoenthaler M. Ultra-mini PCNL versus flexible ureteroscopy: a matched analysis of analgesic consumption and treatment-related patient satisfaction in patients with renal stones 10-35 mm. World J Urol. 2015;33:2131–6.CrossRef
15.
go back to reference Choo MS, Uhmn S, Kim JK, Han JH, Kim DH, Kim J, Lee SH. A prediction model using machine learning algorithm for assessing stone-free status after single session shock wave lithotripsy to treat ureteral stones. J Urol. 2018;200:1371–7.CrossRef Choo MS, Uhmn S, Kim JK, Han JH, Kim DH, Kim J, Lee SH. A prediction model using machine learning algorithm for assessing stone-free status after single session shock wave lithotripsy to treat ureteral stones. J Urol. 2018;200:1371–7.CrossRef
16.
go back to reference Zeng G, Zhang T, Agrawal M, He X, Zhang W, Xiao K, Li H, Li X, Xu C, Yang S, de la Rosette JJ, Fan J, Zhu W, Sarica K. Super-mini percutaneous nephrolithotomy (SMP) vs retrograde intrarenal surgery for the treatment of 1-2 cm lower-pole renal calculi: an international multicentre randomised controlled trial. BJU Int. 2018;122:1034–40.CrossRef Zeng G, Zhang T, Agrawal M, He X, Zhang W, Xiao K, Li H, Li X, Xu C, Yang S, de la Rosette JJ, Fan J, Zhu W, Sarica K. Super-mini percutaneous nephrolithotomy (SMP) vs retrograde intrarenal surgery for the treatment of 1-2 cm lower-pole renal calculi: an international multicentre randomised controlled trial. BJU Int. 2018;122:1034–40.CrossRef
17.
go back to reference Lee SW, Chaiyakunapruk N, Chong HY, Liong ML. Comparative effectiveness and safety of various treatment procedures for lower pole renal calculi: a systematic review and network meta-analysis. BJU Int. 2015;116:252–64.CrossRef Lee SW, Chaiyakunapruk N, Chong HY, Liong ML. Comparative effectiveness and safety of various treatment procedures for lower pole renal calculi: a systematic review and network meta-analysis. BJU Int. 2015;116:252–64.CrossRef
18.
go back to reference Koo V, Young M, Thompson T, Duggan B. Cost-effectiveness and efficiency of shockwave lithotripsy vs flexible ureteroscopic holmium:yttrium-aluminium-garnet laser lithotripsy in the treatment of lower pole renal calculi. BJU Int. 2011;108:1913–6.CrossRef Koo V, Young M, Thompson T, Duggan B. Cost-effectiveness and efficiency of shockwave lithotripsy vs flexible ureteroscopic holmium:yttrium-aluminium-garnet laser lithotripsy in the treatment of lower pole renal calculi. BJU Int. 2011;108:1913–6.CrossRef
19.
go back to reference Bozzini G, Verze P, Arcaniolo D, Dal Piaz O, Buffi NM, Guazzoni G, Provenzano M, Osmolorskij B, Sanguedolce F, Montanari E, Macchione N, Pummer K, Mirone V, De Sio M, Taverna G. A prospective randomized comparison among SWL, PCNL and RIRS for lower calyceal stones less than 2 cm: a multicenter experience: a better understanding on the treatment options for lower pole stones. World J Urol. 2017;35:1967–75.CrossRef Bozzini G, Verze P, Arcaniolo D, Dal Piaz O, Buffi NM, Guazzoni G, Provenzano M, Osmolorskij B, Sanguedolce F, Montanari E, Macchione N, Pummer K, Mirone V, De Sio M, Taverna G. A prospective randomized comparison among SWL, PCNL and RIRS for lower calyceal stones less than 2 cm: a multicenter experience: a better understanding on the treatment options for lower pole stones. World J Urol. 2017;35:1967–75.CrossRef
20.
go back to reference Kang SK, Cho KS, Kang DH, Jung HD, Kwon JK, Lee JY. Systematic review and meta-analysis to compare success rates of retrograde intrarenal surgery versus percutaneous nephrolithotomy for renal stones &gt;2 cm: An update. Med (Baltimore). 2017;96:e9119.CrossRef Kang SK, Cho KS, Kang DH, Jung HD, Kwon JK, Lee JY. Systematic review and meta-analysis to compare success rates of retrograde intrarenal surgery versus percutaneous nephrolithotomy for renal stones &gt;2 cm: An update. Med (Baltimore). 2017;96:e9119.CrossRef
21.
go back to reference Al QS, Abdelhamied MH, AlMuhrij AH, Al RM, Al AA, Abdelhamid AM, Fath ET, Galal EM, Eladawy MS. Prospective comparative study between the effect of CIDEX((R)) OPA and STERRAD NX on the durability of digital flexible ureteroscope. World J Urol. 2019. [Epub ahead of print]. Al QS, Abdelhamied MH, AlMuhrij AH, Al RM, Al AA, Abdelhamid AM, Fath ET, Galal EM, Eladawy MS. Prospective comparative study between the effect of CIDEX((R)) OPA and STERRAD NX on the durability of digital flexible ureteroscope. World J Urol. 2019. [Epub ahead of print].
22.
go back to reference Ozimek T, Cordes J, Gilbert N, Hupe MC, Wiessmeyer JR, Schneider MH, Merseburger AS, Kramer MW. Laser fibre, rather than the stone, may harm the scope: retrospective monocentric analysis of 26 pre- and intraoperative factors of flexible ureteroscope (fURS) damage. World J Urol. 2019. [Epub ahead of print]. Ozimek T, Cordes J, Gilbert N, Hupe MC, Wiessmeyer JR, Schneider MH, Merseburger AS, Kramer MW. Laser fibre, rather than the stone, may harm the scope: retrospective monocentric analysis of 26 pre- and intraoperative factors of flexible ureteroscope (fURS) damage. World J Urol. 2019. [Epub ahead of print].
23.
go back to reference Taguchi K, Harper JD, Stoller ML, Duty BD, Sorensen MD, Sur RL, Usawachintachit M, Tzou DT, Wenzler DL, Isaacson D, Xu A, Chu C, Zaid UB, Taylor ER, Ramaswamy K, Chi T. Identifying factors associated with need for flexible ureteroscope repair: a Western Endourology STone (WEST) research consortium prospective cohort study. Urolithiasis. 2018;46:559–66.CrossRef Taguchi K, Harper JD, Stoller ML, Duty BD, Sorensen MD, Sur RL, Usawachintachit M, Tzou DT, Wenzler DL, Isaacson D, Xu A, Chu C, Zaid UB, Taylor ER, Ramaswamy K, Chi T. Identifying factors associated with need for flexible ureteroscope repair: a Western Endourology STone (WEST) research consortium prospective cohort study. Urolithiasis. 2018;46:559–66.CrossRef
24.
go back to reference Singh DU, Limbu Y. Safety and efficacy of percutaneous Nephrolithotomy in children. J Nepal Health Res Counc. 2017;15:130–4.CrossRef Singh DU, Limbu Y. Safety and efficacy of percutaneous Nephrolithotomy in children. J Nepal Health Res Counc. 2017;15:130–4.CrossRef
25.
go back to reference Xu Y, Min Z, Wan SP, Nie H, Duan G. Complications of retrograde intrarenal surgery classified by the modified Clavien grading system. Urolithiasis. 2018;46:197–202.CrossRef Xu Y, Min Z, Wan SP, Nie H, Duan G. Complications of retrograde intrarenal surgery classified by the modified Clavien grading system. Urolithiasis. 2018;46:197–202.CrossRef
26.
go back to reference Tokas T, Skolarikos A, Herrmann T, Nagele U. Pressure matters 2: intrarenal pressure ranges during upper-tract endourological procedures. World J Urol. 2019;37:133–42.CrossRef Tokas T, Skolarikos A, Herrmann T, Nagele U. Pressure matters 2: intrarenal pressure ranges during upper-tract endourological procedures. World J Urol. 2019;37:133–42.CrossRef
27.
go back to reference Wilhelm K, Muller PF, Schulze-Ardey J, Spath J, Suarez-Ibarrola R, Miernik A, Schumann S. Characterization of flow-caused Intrarenal pressure conditions during percutaneous Nephrolithotomy in vitro. J Endourol. 2019;33:235–41.CrossRef Wilhelm K, Muller PF, Schulze-Ardey J, Spath J, Suarez-Ibarrola R, Miernik A, Schumann S. Characterization of flow-caused Intrarenal pressure conditions during percutaneous Nephrolithotomy in vitro. J Endourol. 2019;33:235–41.CrossRef
28.
go back to reference Cindolo L, Castellan P, Scoffone CM, Cracco CM, Celia A, Paccaduscio A, Schips L, Proietti S, Breda A, Giusti G. Mortality and flexible ureteroscopy: analysis of six cases. World J Urol. 2016;34:305–10.CrossRef Cindolo L, Castellan P, Scoffone CM, Cracco CM, Celia A, Paccaduscio A, Schips L, Proietti S, Breda A, Giusti G. Mortality and flexible ureteroscopy: analysis of six cases. World J Urol. 2016;34:305–10.CrossRef
29.
go back to reference Desai JD. Prospective outcomes of 11-13Ch. Ultra-mini percutaneous nephrolithotomy (UMP): a consecutive cohort study. Arch Esp Urol. 2017;70:202–10.PubMed Desai JD. Prospective outcomes of 11-13Ch. Ultra-mini percutaneous nephrolithotomy (UMP): a consecutive cohort study. Arch Esp Urol. 2017;70:202–10.PubMed
Metadata
Title
Comparative analysis of retrograde intrarenal surgery and modified ultra-mini percutaneous nephrolithotomy in management of lower pole renal stones (1.5–3.5 cm)
Authors
Zhuohang Li
Cong Lai
Arvind K. Shah
Weibin Xie
Cheng Liu
Li Huang
Kuiqing Li
Hao Yu
Kewei Xu
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2020
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/s12894-020-00586-6

Other articles of this Issue 1/2020

BMC Urology 1/2020 Go to the issue