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BMC Urology
Published in: BMC Urology 1/2017

Open Access 01-12-2017 | Research article

Symptom clusters and related factors in bladder cancer patients three months after radical cystectomy

Authors: Hongyan Ren, Ping Tang, Qinghua Zhao, Guosheng Ren

Published in: BMC Urology | Issue 1/2017

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Abstract

Background

To identify symptom distress and clusters in patients 3 months after radical cystectomy and to explore their potential predictors.

Methods

A cross-sectional design was used to investigate 99 bladder cancer patients 3 months after radical cystectomy. Data were collected by demographic and disease characteristic questionnaires, the symptom experience scale of the M.D. Anderson symptom inventory, two additional symptoms specific to radical cystectomy, and the functional assessment of cancer therapy questionnaire. A factor analysis, stepwise regression, and correlation analysis were applied.

Results

Three symptom clusters were identified: fatigue-malaise, gastrointestinal, and psycho-urinary. Age, complication severity, albumin post-surgery (negative), orthotropic neobladder reconstruction, adjuvant chemotherapy and American Society of Anesthesiologists (ASA) scores were significant predictors of fatigue-malaise. Adjuvant chemotherapy, orthotropic neobladder reconstruction, female gender, ASA scores and albumin (negative) were significant predictors of gastrointestinal symptoms. Being unmarried, having a higher educational level and complication severity were significant predictors of psycho-urinary symptoms. The correlations between clusters and for each cluster with quality of life were significant, with the highest correlation observed between the psycho-urinary cluster and quality of life.

Conclusions

Bladder cancer patients experience concurrent symptoms that appear to cluster and are significantly correlated with quality of life. Moreover, symptom clusters may be predicted by certain demographic and clinical characteristics.
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Metadata
Title
Symptom clusters and related factors in bladder cancer patients three months after radical cystectomy
Authors
Hongyan Ren
Ping Tang
Qinghua Zhao
Guosheng Ren
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2017
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/s12894-017-0255-x

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