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Published in: BMC Surgery 1/2015

Open Access 01-12-2015 | Case report

Hepatic Sclerosed Hemangioma: a case report and review of the literature

Authors: Shunsuke Miyamoto, Akihiko Oshita, Yutaka Daimaru, Masaru Sasaki, Hideki Ohdan, Atsushi Nakamitsu

Published in: BMC Surgery | Issue 1/2015

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Abstract

Background

Although cavernous hemangioma is one of the most frequently encountered benign hepatic neoplasms, hepatic sclerosed hemangioma is very rare. We report a case of hepatic sclerosed hemangioma that was difficult to distinguish from an intrahepatic cholangiocarcinoma by imaging studies.

Case presentation

A 76-year-old male patient with right hypochondralgia was referred to our hospital. Abdominal ultrasonography revealed a heterogeneously hyperechoic tumor that was 59 mm in diameter in segment 7 of the liver. Dynamic computed tomography showed a low-density tumor with delayed ring enhancement. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (EOB-MRI) demonstrated a low-signal intensity mass with ring enhancement on T1-weighted images. The mass had several high-signal intensity lesions on T2-weighted images. EOB-MRI revealed a hypointense nodule on the hepatobiliary phase. From these imaging studies, the tumor was diagnosed as intrahepatic cholangiocarcinoma, and we performed laparoscopy-assisted posterior sectionectomy of the liver with lymph node dissection in the hepatoduodenal ligament. Histopathological examination revealed a hepatic sclerosed hemangioma with hyalinized tissue and collagen fibers.

Conclusion

Hepatic sclerosed hemangioma is difficult to diagnose preoperatively because of its various imaging findings. We report a case of hepatic sclerosed hemangioma and review the literatures, especially those concerning imaging findings.
Literature
1.
go back to reference Ishii T, Takahara O, Sano I, Taniguchi H, Nakao S, Eida K, et al. Sclerosing Hemangioma of the liver. Nagasaki Med J. 1995;70(1):23–6. Ishii T, Takahara O, Sano I, Taniguchi H, Nakao S, Eida K, et al. Sclerosing Hemangioma of the liver. Nagasaki Med J. 1995;70(1):23–6.
2.
go back to reference Doyle DJ, Khalili K, Guindi M, Atri M. Imaging features of sclerosed hemangioma. Am J Roentgenol. 2007;189(1):67–72.CrossRef Doyle DJ, Khalili K, Guindi M, Atri M. Imaging features of sclerosed hemangioma. Am J Roentgenol. 2007;189(1):67–72.CrossRef
3.
go back to reference Berry CL. Solitary “necrotic nodules” of the liver: a probable pathogenesis. J Chin Pathol. 1985;38(11):1278–90.CrossRef Berry CL. Solitary “necrotic nodules” of the liver: a probable pathogenesis. J Chin Pathol. 1985;38(11):1278–90.CrossRef
4.
go back to reference Haratake J, Arai K, Makino H. Hemangioma and hyalinized hemangioma. Jpn J Clin Med. 1995;7:336–8. Haratake J, Arai K, Makino H. Hemangioma and hyalinized hemangioma. Jpn J Clin Med. 1995;7:336–8.
5.
go back to reference Kobayashi S, Demachi H, Akakura Y, Miyata S, Konishi K, Tsuji M, et al. A case of sclerosing cavernous hemangioma of the liver. Jpn J Clin Radiol. 1996;41:567–70. Kobayashi S, Demachi H, Akakura Y, Miyata S, Konishi K, Tsuji M, et al. A case of sclerosing cavernous hemangioma of the liver. Jpn J Clin Radiol. 1996;41:567–70.
6.
go back to reference Ukai K, Onidera H, Mikuni J, Ouchi K. A case of sclerosed hemangioma of the liver. Liver. 1998;39(9):638–42. Ukai K, Onidera H, Mikuni J, Ouchi K. A case of sclerosed hemangioma of the liver. Liver. 1998;39(9):638–42.
7.
go back to reference Yamashita Y, Shimada M, Taguchi K, Gion T, Hasegawa H, Utsunomiya T, et al. Hepatic sclerosing hemangioma mimicking a metastatic liver tumor: report of a case. Surg Today. 2000;30:849–52.CrossRefPubMed Yamashita Y, Shimada M, Taguchi K, Gion T, Hasegawa H, Utsunomiya T, et al. Hepatic sclerosing hemangioma mimicking a metastatic liver tumor: report of a case. Surg Today. 2000;30:849–52.CrossRefPubMed
8.
go back to reference Okada S, Tsuyama H, Kurita K, Onchi H, Inoue T, Kinoshita K, et al. A case of sclerosing hemangioma with cancer of the desending colon. J Jpn Surg Assoc. 2001;62(3):757–60.CrossRef Okada S, Tsuyama H, Kurita K, Onchi H, Inoue T, Kinoshita K, et al. A case of sclerosing hemangioma with cancer of the desending colon. J Jpn Surg Assoc. 2001;62(3):757–60.CrossRef
9.
go back to reference Aibe H, Honda H, Kuroiwa T, Yoshimitsu K, Irie H, Tajima T, et al. Sclerosed hemangioma of the liver. Abdom Imaging. 2001;26:496–9.CrossRefPubMed Aibe H, Honda H, Kuroiwa T, Yoshimitsu K, Irie H, Tajima T, et al. Sclerosed hemangioma of the liver. Abdom Imaging. 2001;26:496–9.CrossRefPubMed
10.
go back to reference Hayakawa T, Itou M, Taniguchi S, Ideno M, Konno T, Hatayama J. A case of sclerosing hemangioma of the liver. J Med Assoc South Hokkaido. 2001;38:180–3. Hayakawa T, Itou M, Taniguchi S, Ideno M, Konno T, Hatayama J. A case of sclerosing hemangioma of the liver. J Med Assoc South Hokkaido. 2001;38:180–3.
11.
go back to reference Lee VT, Magnaye M, Tan HW, Thng CH, Ooi LL. Sclerosing haemangioma mimicking hepatocellular carcinoma. Singapore Med J. 2005;46(3):140–3.PubMed Lee VT, Magnaye M, Tan HW, Thng CH, Ooi LL. Sclerosing haemangioma mimicking hepatocellular carcinoma. Singapore Med J. 2005;46(3):140–3.PubMed
12.
go back to reference Morikawa M, Ishida M, Iida A, Katayama K, Yamaguchi A, Imamura Y. Sclerosed hemangioma of the liver mimicking metastatic liver cancer. J Jpn Surg Assoc. 2005;66(7):1698–702.CrossRef Morikawa M, Ishida M, Iida A, Katayama K, Yamaguchi A, Imamura Y. Sclerosed hemangioma of the liver mimicking metastatic liver cancer. J Jpn Surg Assoc. 2005;66(7):1698–702.CrossRef
13.
go back to reference Okamoto E, Satou S, Takahashi Y, Ohshima N, Azumi T, Furuta K, et al. A case of hepatic sclerosed hemangioma in patient with fatty liver. J Shimane Med Assoc. 2005;25(3):60–4. Okamoto E, Satou S, Takahashi Y, Ohshima N, Azumi T, Furuta K, et al. A case of hepatic sclerosed hemangioma in patient with fatty liver. J Shimane Med Assoc. 2005;25(3):60–4.
14.
go back to reference Hamatsu T, Kuroda Y, Hunahashi S, Shima I, Iso Y. Sclerosed hemangioma of the liver mimicking metastatic liver tumor of colon cancer. J Jpn Surg Assoc. 2006;67(4):856–60.CrossRef Hamatsu T, Kuroda Y, Hunahashi S, Shima I, Iso Y. Sclerosed hemangioma of the liver mimicking metastatic liver tumor of colon cancer. J Jpn Surg Assoc. 2006;67(4):856–60.CrossRef
15.
go back to reference Hayashi K, Ohara H, Kitajima Y, Tanaka S, Takada H, Imai E, et al. A case of hepatic sclerosed hemangioma mimicking gastric submucosal tumor. Kanzo. 2006;47(10):474–81.CrossRef Hayashi K, Ohara H, Kitajima Y, Tanaka S, Takada H, Imai E, et al. A case of hepatic sclerosed hemangioma mimicking gastric submucosal tumor. Kanzo. 2006;47(10):474–81.CrossRef
16.
go back to reference Iida H, Tango Y, Tsutamoto Y, Harimura T, Tanaka K, Takao T, et al. A resected case of Sclerosed hemangioma. Jpn J Gastroenterol Surg. 2006;39(9):1493–7.CrossRef Iida H, Tango Y, Tsutamoto Y, Harimura T, Tanaka K, Takao T, et al. A resected case of Sclerosed hemangioma. Jpn J Gastroenterol Surg. 2006;39(9):1493–7.CrossRef
17.
go back to reference Sawai K, Ueda N, Senda K, Kimura T, Sawa T. A case of sclerosing hemangioma of the liver. J Jpn Surg Assoc. 2007;68(9):2293–8.CrossRef Sawai K, Ueda N, Senda K, Kimura T, Sawa T. A case of sclerosing hemangioma of the liver. J Jpn Surg Assoc. 2007;68(9):2293–8.CrossRef
18.
go back to reference Kaji S, Koike N, Suzuki S, Harada N, Suzuki M, Hanyu F. A case of hepatic sclerosed hemangioma mimicking cholangiocell carcinoma. J Jpn Surg Assoc. 2008;69(5):1181–5.CrossRef Kaji S, Koike N, Suzuki S, Harada N, Suzuki M, Hanyu F. A case of hepatic sclerosed hemangioma mimicking cholangiocell carcinoma. J Jpn Surg Assoc. 2008;69(5):1181–5.CrossRef
19.
go back to reference Tsumaki N, Waguri N, Yoneyama O, Hama I, Kawahisa J, Yokoo K, et al. A case of hepatic sclerosed hemangioma with a significant morphological change over a period of 17 years. Kanzo. 2008;49(6):268–74.CrossRef Tsumaki N, Waguri N, Yoneyama O, Hama I, Kawahisa J, Yokoo K, et al. A case of hepatic sclerosed hemangioma with a significant morphological change over a period of 17 years. Kanzo. 2008;49(6):268–74.CrossRef
20.
go back to reference Mori H, Ikegami T, Imura S, Shimada M, Morine Y, Kanemura H, et al. Sclerosed hemangioma of the liver: report of a case and review of the literature. Hepatol Res. 2008;38:529–33.CrossRefPubMed Mori H, Ikegami T, Imura S, Shimada M, Morine Y, Kanemura H, et al. Sclerosed hemangioma of the liver: report of a case and review of the literature. Hepatol Res. 2008;38:529–33.CrossRefPubMed
21.
go back to reference Yoshida T, Sugimachi K, Gion T, Soejima Y, Aijima S, Takatomi S, et al. A case of sclerosing hemangioma mimicking a malignant liver tumor. J Clin Surg. 2010;65(3):451–5. Yoshida T, Sugimachi K, Gion T, Soejima Y, Aijima S, Takatomi S, et al. A case of sclerosing hemangioma mimicking a malignant liver tumor. J Clin Surg. 2010;65(3):451–5.
22.
go back to reference Usui T, Shiozawa S, Kim DH, Tsuchiya A, Kuhara K, Yokomizo H, et al. A case of sclerosed hemangioma mimicking a metastatic liver tumor. J Jpn Coll Surg. 2010;35(1):89–93. Usui T, Shiozawa S, Kim DH, Tsuchiya A, Kuhara K, Yokomizo H, et al. A case of sclerosed hemangioma mimicking a metastatic liver tumor. J Jpn Coll Surg. 2010;35(1):89–93.
24.
go back to reference Hida T, Nishie A, Tajima T, Taketomi A, Aishima S, Honda H. Sclerosed hemangioma of the liver: possible diagnostic value of diffusion-weighted magnetic resonance imaging. Jpn J Radiol. 2010;28:235–8.CrossRefPubMed Hida T, Nishie A, Tajima T, Taketomi A, Aishima S, Honda H. Sclerosed hemangioma of the liver: possible diagnostic value of diffusion-weighted magnetic resonance imaging. Jpn J Radiol. 2010;28:235–8.CrossRefPubMed
25.
go back to reference Miyaki D, Aikata H, Waki K, Murakami E, Hashimoto Y, Nagaoki Y, et al. Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study. Nihon Shokakibyo Gakkai Zasshi. 2011;108(6):954–61.PubMed Miyaki D, Aikata H, Waki K, Murakami E, Hashimoto Y, Nagaoki Y, et al. Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study. Nihon Shokakibyo Gakkai Zasshi. 2011;108(6):954–61.PubMed
26.
go back to reference Kitami C, Kawachi Y, Nishimura A, Makino S, Kawahara M, Nikuni K. Sclerosed hemangioma of the liver -report of a case-. J Jpn Surg Assoc. 2011;72(12):3120–4.CrossRef Kitami C, Kawachi Y, Nishimura A, Makino S, Kawahara M, Nikuni K. Sclerosed hemangioma of the liver -report of a case-. J Jpn Surg Assoc. 2011;72(12):3120–4.CrossRef
27.
go back to reference Tanaka T, Moriya T, Fukuda S, Yoshifuku Y, Fujino H, Miwata T, et al. A case of sclerosed hemangioma of the liver was difficult to differentiate hepatocellular carcinoma was found during examination of chronic hepatitis C. HBP Imaging. 2011;13(6):646–52. Tanaka T, Moriya T, Fukuda S, Yoshifuku Y, Fujino H, Miwata T, et al. A case of sclerosed hemangioma of the liver was difficult to differentiate hepatocellular carcinoma was found during examination of chronic hepatitis C. HBP Imaging. 2011;13(6):646–52.
28.
go back to reference Mikami J, Tominaga M, Sendo H, Maeda Y, Fujino Y, Koma Y, et al. A case of hepatic sclerosing hemangioma mimicking a malignant liver tumor. J Jpn Surg Assoc. 2011;72(4):965–71.CrossRef Mikami J, Tominaga M, Sendo H, Maeda Y, Fujino Y, Koma Y, et al. A case of hepatic sclerosing hemangioma mimicking a malignant liver tumor. J Jpn Surg Assoc. 2011;72(4):965–71.CrossRef
30.
go back to reference Wakasugi M, Ueshima N, Akamatsu D, Tori M, Tsujimoto M, Nishida T. A case of multiple sclerosed hemangioma mimicking a metastatic liver tumor. J Clin Surg. 2012;67(12):1461–5. Wakasugi M, Ueshima N, Akamatsu D, Tori M, Tsujimoto M, Nishida T. A case of multiple sclerosed hemangioma mimicking a metastatic liver tumor. J Clin Surg. 2012;67(12):1461–5.
31.
go back to reference Yamada S, Shimada M, Utsunomiya T, Morine Y, Imura S, Ikemoto T, et al. Hepatic sclerosed hemangioma which was misdiagnosed as metastasis of gastric cancer : report of a case. J Med Invest. 2012;59:270–4.CrossRefPubMed Yamada S, Shimada M, Utsunomiya T, Morine Y, Imura S, Ikemoto T, et al. Hepatic sclerosed hemangioma which was misdiagnosed as metastasis of gastric cancer : report of a case. J Med Invest. 2012;59:270–4.CrossRefPubMed
33.
go back to reference Shimada Y, Takahashi Y, Iguchi H, Yamazaki H, Tsunoda H, Watanabe M, et al. A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years: a case report. J Med Case Rep. 2013;28(7):139.CrossRef Shimada Y, Takahashi Y, Iguchi H, Yamazaki H, Tsunoda H, Watanabe M, et al. A hepatic sclerosed hemangioma with significant morphological change over a period of 10 years: a case report. J Med Case Rep. 2013;28(7):139.CrossRef
34.
go back to reference Goodman ZD. Benign tumors of the liver. In: Okuda K, Ishak KG, editors. Neoplasm of the liver. Tokyo: Springer; 1987. p. 105–25.CrossRef Goodman ZD. Benign tumors of the liver. In: Okuda K, Ishak KG, editors. Neoplasm of the liver. Tokyo: Springer; 1987. p. 105–25.CrossRef
35.
go back to reference Makhlouf HR, Ishak KG. Sclerosed hemangioma and sclerosing cavernous hemangioma of the liver: a comparative clinicopathologic and immunohistochemical study with emphasis on the role of mast cells in their histogenesis. Liver. 2002;22(1):70–8.CrossRefPubMed Makhlouf HR, Ishak KG. Sclerosed hemangioma and sclerosing cavernous hemangioma of the liver: a comparative clinicopathologic and immunohistochemical study with emphasis on the role of mast cells in their histogenesis. Liver. 2002;22(1):70–8.CrossRefPubMed
Metadata
Title
Hepatic Sclerosed Hemangioma: a case report and review of the literature
Authors
Shunsuke Miyamoto
Akihiko Oshita
Yutaka Daimaru
Masaru Sasaki
Hideki Ohdan
Atsushi Nakamitsu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2015
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-015-0029-x

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