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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2019

Open Access 01-12-2019 | Osteonecrosis | Research article

Three-dimensional finite element analysis of silk protein rod implantation after core decompression for osteonecrosis of the femoral head

Authors: Liangta Huang, Feiyan Chen, Siqun Wang, Yibing Wei, Gangyong Huang, Jie Chen, Jingsheng Shi, Rajeev K. Naidu, Jun Xia, Tiger H. Tao

Published in: BMC Musculoskeletal Disorders | Issue 1/2019

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Abstract

Background

Several methods are available for the treatment of early-stage osteonecrosis of the femoral head. Core decompression with implantation is a widely-used treatment. However, no single implant is recognized as the most effective way to prevent disease progression. Silk has high strength and resiliency. This study explored the possibility of a strong and resilient silk protein biomaterial as a new alternative implant.

Methods

We investigated the biomechanical properties of the silk protein material by regular compression, torsion, and three-point bending tests. We established three-dimensional finite element models of different degrees of femoral head osteonecrosis following simple core decompression, fibula implantation, porous tantalum rod implantation, and silk protein rod implantation. Finally, we compared the differences in displacement and surface stress under load at the femoral head weight-bearing areas between these models.

Results

The elastic modulus and shear modulus of the silk protein material was 0.49GPa and 0.66GPa, respectively. Three-dimensional finite element analyses demonstrated less displacement and surface stress at the femoral head weight-bearing areas following silk protein rod implantation compared to simple core decompression (p < 0.05), regardless of the extent of osteonecrosis. No differences were noted in the surface deformation or surface stress of the femoral head weight-bearing areas following silk protein rod, fibula or tantalum rod implantation (p > 0.05).

Conclusions

When compared with simple core decompression, silk protein rod implantation demonstrated less displacement and surface stress at the femoral head weight-bearing area, but more than fibula or tantalum rod implantation. Similar effects on the surface stress of the femoral head between the silk rod, fibula and tantalum rod implantations, combined with additional modifiable properties support the use of silk protein as a suitable biomaterial in osteonecrosis surgery.
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Metadata
Title
Three-dimensional finite element analysis of silk protein rod implantation after core decompression for osteonecrosis of the femoral head
Authors
Liangta Huang
Feiyan Chen
Siqun Wang
Yibing Wei
Gangyong Huang
Jie Chen
Jingsheng Shi
Rajeev K. Naidu
Jun Xia
Tiger H. Tao
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2019
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-019-2914-4

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