Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2018

Open Access 01-12-2018 | Study protocol

The knitting community-based trial for older women with osteoarthritis of the hands: design and rationale of a randomized controlled trial

Authors: Paulette Guitard, Lucie Brosseau, George A. Wells, Nicole Paquet, Gail Paterson, Karine Toupin-April, Sabrina Cavallo, Sibel Z. Aydin, Guillaume Léonard, Gino De Angelis

Published in: BMC Musculoskeletal Disorders | Issue 1/2018

Login to get access

Abstract

Background

The prevalence of hand osteoarthritis (HOA) has been reported to be higher amongst women over 50 years old (66%) compared to men of the same age (34%). Although exercise therapy has been shown effective in reducing symptoms and disability associated with HOA, adherence to treatment programs remains low. The primary objective of this RCT is to examine the effectiveness of a 12-week knitting program for morning stiffness (primary outcome) and pain relief (secondary outcome) 2 h post-wakening in females (aged 50 to 85 years old) with mild to moderate hand osteoarthritis (HOA).

Methods/design

A single-blind, two-arm randomized controlled trial (RCT) with a parallel group design will be used to reach this objective and compare results to a control group receiving an educational pamphlet on osteoarththritis (OA) designed by the Arthritis Society. The premise behind the knitting program is to use a meaningful occupation as the main component of an exercise program. The knitting program will include two components: 1) bi-weekly 20-min knitting sessions at a senior’s club and 2) 20-min home daily knitting sessions for the five remaining weekdays. Participants assigned to the control group will be encouraged to read the educational pamphlet and continue with usual routine. Pain, morning stiffness, hand function, self-efficacy and quality of life will be measured at baseline, six weeks, 12 weeks (end of program) with standardized tools. We hypothesize that participants in the knitting program will have significant improvements in all clinical outcomes compared to the control group.
A published case study as well as the preliminary results of a feasibility study as examined through a 6-week pre-post study (n = 5 women with HOA) involving 20-min daily knitting morning sessions led to this proposed randomized controlled trial research protocol. This article describes the intervention, the empirical evidence to support it.

Discussion

This knitting RCT has the potential to enhance our understanding of the daily HOA symptoms control and exercise adherence, refine functional exercise recommendations in this prevalent disease, and reduce the burden of disability in older women.

Trial Registration

(ACTRN12617000843358) registered on 7/06/2017.
Literature
1.
Pereira D, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E. The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review. Osteoarthr Cartil. 2011;19:1270–85.CrossRefPubMed
2.
Cho HJ, Morey V, Kang JY. Prevalence and risk factors of spine, shoulder, hand, hip, and knee osteoarthritis in community-dwelling Koreans older than age 65 years. Clin Orthop Relat Res. 2015;473:3307–14.CrossRefPubMedPubMedCentral
3.
Haugen IK, Englund M, Aliabadi P, Niu J, Clancy M, Kvien TK, Felson DT. Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham osteoarthritis study. Ann Rheum Dis. 2011;70(9):1–15.CrossRef
4.
Liu R, Damman W, Kaptein AA, Rosendaal FR, Kloppenburg M. Coping styles and disability in patients with hand osteoarthritis. Rheumatology. 2016;55:4118.
5.
Kjeken I, Grotle M, Hagen KB, Østerås N. Development of an evidence-based exercise programme for people with hand osteoarthritis. Scand J of Occup Ther. 2015;22(2):103–16.CrossRef
6.
Hill S, Dziedzic KS, Ong BN. The functional and psychological impact of hand osteoarthritis. Chronic Illness. 2010;6:101–10.CrossRefPubMed
7.
Østerås N, Hagen KB, Grotle M, Sand-Svartrud AL, Mowinckel P, Kjeken I. Limited effects of exercises in people with hand osteoarthritis: results from a randomized controlled trial. Osteoarthr Cartil. 2014a;22(9):1224–33.
8.
Østerås N, Kjeken I, Smedslund G,Moe RH, Slatkowsky-Christensen B, Uhlig T, Hagen KB. Exercise for hand osteoarthritis. Cochrane database of systematic reviews 2017, issue 1. Art. No.: CD010388. DOI: 10.1002/14651858.CD010388.pub2.
9.
Stamm TA, Machold KP, Smolen JS, Fischer S, Redlich K, Graninger W, Ebner W, Erlacher L. Joint protection and home hand exercises improve hand function in patients with hand osteoarthritis: a randomized controlled trial. Arthritis & Rheumatism. Arthritis Care & Research. 2002;47(1):44–9.CrossRef
10.
Brosseau L, Wells GA, Tugwell P, Egan M, Dubouloz CJ, Casimiro L, Robinson V, Pelland L, McGowan J, Lamb M. Ottawa panel evidence-based clinical practice guidelines for therapeutic exercises and manual therapy in the treatment of osteoarthritis. Phys Ther. 2005a;85:907–71.
11.
Rogers MW, Wilder FV. The effects of strength training among persons with hand osteoarthritis: a two-year follow-up study. J Hand Ther. 2007;20:244–9.CrossRefPubMed
12.
Zhang W, Doherty M, Leeb BF, Alekseeva L, Arden NK, Bijlsma JW, et al. EULAR evidence based recommendations for the management of hand osteoarthritis: report of a task force of the EULAR standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2007;66:377–38.CrossRefPubMed
13.
Lefler C, Armstrong J. Exercise in the treatment of osteoarthritis in the hands of the elderly. Clin Kinesiol. 2004;58:13–7.
14.
Ye L, Kalichman L, Spittle A, Dobson F, Bennell K. Effects of rehabilitative interventions on pain, function and physical impairments in people with hand osteoarthritis: a systematic review. Arthritis Res Ther. 2011;13:R28.CrossRefPubMedPubMedCentral
15.
16.
Hochberg MC, Altman RD, Toupin-April K, Benkhalti M, Guyatt G, Mcgowan J, Towheed T, Welch V, Wells GA, Tugwell P. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care & Research Vol 64, No 4. 2012:465–74. https://​doi.​org/​10.​1002/​acr.​21596.
17.
18.
19.
Valdes K, Marik T. A systematic review of conservative interventions for osteoarthritis of the hand. J Hand Ther. 2010;23:334–51.CrossRefPubMed
20.
Mahendira D, Towheed TE. Systematic review of non-surgical therapies for osteoarthritis of the hand: an update. Osteoarthr Cartil. 2009;17:1263–8.CrossRefPubMed
21.
Bement M, Weyer A, Hartley S, Yoon S, Hunter S. Fatiguing exercise attenuates pain-induced corticomotor excitability. Neurosci Lett. 2009;452:209–13.CrossRef
22.
Bement MH. Exercise-induced hypoalgesia: an evidence-based review. In: Sluka KA, editor. Mechanisms and Management of Pain for the Physical Therapist. Seattle: IASP Press; 2009. p. 143–66.
23.
Koltyn KF. Exercise-induced Hypoalgesia and intensity of exercise. Sports Med. 2002;32(8):477–87.CrossRefPubMed
24.
Koltyn KF. Using physical activity to manage pain in older adults. J Aging Phys Act. 2002;10:226–39.CrossRef
25.
Regnaux JP, Lefevre-Colau MM, Trinquart L, Nguyen C, Boutron I, Brosseau L, Ravaud P. High-intensity versus low-intensity physical activity or exercise in patients with hip or knee osteoarthritis (Cochrane review). Cochrane database of systematic reviews (Online). 2015;10(2):CD010203.
26.
Damush TM, Perkins SM, Mikesky AE, Roberts M, Motivational O'DJ. Factors influencing older adults diagnosed with knee osteoarthritis to join and maintain an exercise program. J Aging Phys Act. 2005;13:5–60.CrossRef
27.
Hoffman MD, Hoffman DR. Exercisers achieve greater acute exercise-induced mood enhancement than nonexercisers. Arch Phys Med Rehabil. 2008;29:358–63.CrossRef
28.
Townsend EA, Polatajko HJ. Enabling occupation II: advancing an occupational therapy vision for health, well-being and justice through occupation. 2nd ed. Ottawa: CAOT; 2013.
29.
Schutzer KA, Graves BS. Barriers and motivations to exercise in older adults. Prev Med. 2004;39:1056–61.CrossRefPubMed
30.
Krauss I, Katzmarek U, Rieger MA, Sudeck G. Motives for physical exercise participation as a basis for the development of patient-oriented exercise interventions in osteoarthritis: a cross-sectional study. European Journal of Physical and Rehabilitation Medicine. 2017; https://​doi.​org/​10.​23736/​S1973-9087.​17.​04482-3.
31.
Van Tuyl LHD, Boers M. Patient’s global assessment of disease activity: what are we measuring? Arthritis Rheum. 2012;64(9):2811–3.CrossRefPubMed
32.
Stolee P, Rockwood K, Fox RA, Streiner DL. The use of goal attainment scaling in a geriatric care setting. J Am Geriatr Soc. 1992;40(6):574–8.CrossRefPubMed
33.
Lorig K, Brown BW Jr, Ung E, Chastain R, Shoor S, Holman HR. Development and evaluation of a scale to measure the perceived self-efficacy in people with arthritis. Arthritis Rheum. 1989;32(1):37–44.CrossRefPubMed
34.
Hoeger Bement MK, Dicapo J, Rasiarmos R, Hunter SK. Dose response of isometric contractions on pain perception in healthy adults. American College of Sports Medicine. 2008:40(11):1880–9.
35.
Koltyn KF, Umeda M. Contralateral attenuation of pain after short-duration submaximal isometric exercise. J Pain. 2007;8(11):887–92.CrossRefPubMed
36.
Lemley KJ, Drewek B, Hunter SK, Hoeger Bement MK. Pain relief after isometric exercise is not task-dependent in older men and women. Journal of the American College of Sport. Medicine. 2014;46(1):185–91.
37.
ACSM: American College of Sports Medicine, Pescatello LS. ACSM's guidelines for exercise testing and prescription. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health; 2014. p. 1456.
38.
Østerås N, Risberg MA, Kvien TK, Engebretsen L, Nordsletten L, Schjervheim UB, Haugen I, Hammer HB, Provan S, Øiestad BE, Semb AG, Rollefstad S, Hagen KB, Uhlig T, Slatkowsky-Christensen B, Kjeken I, Flugsrud GB, Grotle M, Sesseng S, Edvardsen H, Natvig B. Hand, hip and knee osteoarthritis in a Norwegian population-based study - the MUST protocol. BMC Musculoskelet Disord. 2013;14:201–10. 1186/1471-2474-14-201CrossRefPubMedPubMedCentral
39.
40.
Villafane JH, CLELAND JA, Fernandez-De-Las-Penas C. The effectiveness of a manual therapy and exercise protocol in patients with thumb carpometacarpal osteoarthritis: a randomized controlled trial. J Orthop Sports Phys Ther. 2013;43(4):204–13.CrossRefPubMed
41.
Hamasaki T, Lalonde L, Harris P, Bureau NJ, Gaudreault N, Ziegler D, Choinière M. Efficacy of treatments and pain management for trapeziometacarpal (thumb base) osteoarthritis: protocol for a systematic review. BMJ Open. 2015;5:1–9.
42.
43.
Brosseau L, May LG. Knitting a promising pain self-management strategy for older woman with osteoarthritic hands? J Clin Rheumatol. 2017;23(3):179–80.CrossRefPubMed
44.
45.
46.
47.
48.
Kloppenburg M, Maheu E, Kraus VB, Cicuttini F, Doherty M, Dreiser RL, Henrotin Y. OARSI clinical trials recommendations: design and conduct of clinical trials for hand osteoarthritis. Osteoarthr Cartil. 2015;23:772–86.CrossRefPubMed
49.
Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol. 2010;63:834e840.CrossRef
50.
Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, Brown C, Cooke TD, Daniel W, Gray R, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis & Rheumatism. 1990;33(11):1601–10.CrossRef
51.
Kallman DA, Wigley FM, JR SWW. New radiographic grading scales for osteoarthritis of the hand. Arthritis Rheum. 1989;32:1584–91.CrossRefPubMed
52.
Doyle DV, Dieppe PA, Scott J, Huskisson EC. An articular index for the assessment of osteoarthritis. Ann Rheumatic Dis. 1981;40:75–8.CrossRef
53.
Vliet Vlieland TP, Zwinderman AH, Breedveld FC, Hazes JM. Measurement of morning stiffness in rheumatoid arthritis clinical trials. J Clin Epidemiol. 1997;50(7):757–63.CrossRefPubMed
54.
Brosseau L, Wells GA, Brooks S, De Angelis G, Bell M, Egan M, Poitras S, King J, Casimiro L, Loew L, Novikov M. People getting a grip on arthritis II: an innovative strategy to implement clinical practice guidelines for rheumatoid arthritis and osteoarthritis patients through Facebook. Health Educ J. 2014;73(1):109–25.CrossRef
55.
56.
57.
Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9(1):97–113.CrossRefPubMed
58.
Veale JF. Edinburgh handedness inventory – short form: a revised version based on confirmatory factor analysis. Laterality. 2014;19:164–77.CrossRefPubMed
59.
Brosseau L, Wells G, Marchand S, Gaboury I, Stokes B, Morin M, Casimiro L, Yonge K, Tugwell P. Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the hand. Lasers Surg Med. 2005b;36:210–9.CrossRefPubMed
60.
Van Tulder MW, Assendett WJ, Koes BW, Bouter LM. Editorial Board of the Cochrane Collaboration Back Review Group. Method guidelines for systematic reviews in the cochrane collaboration back review group for spinal disorders: operationalization of van Tulder’s quality assessment form. Spine. 1997;22:2323–30.CrossRefPubMed
61.
Garfinkel MS, Schumacher HR, Husain A, Levy M, Reshetar RA. Evaluation of a yoga based regimen for treatment of osteoarthritis of the hands. J Rheumatol. 1994;21:2341–3.PubMed
62.
Bellamy N, Campbell J, Haraoui B, Buchbinder R, Hobby K, JC MD. Dimensionality and clinical importance of pain and disability in hand osteoarthritis: development of the Australian/Canadian (AUSCAN) osteoarthritis hand index. Osteoarthr Cartil. 2002;10:855–62.CrossRefPubMed
63.
Bellamy N, Campbell J, Haraoui B, Gerecz-Simon E, Buchbinder R, Hobby K, JC MD. Clinimetric properties of the auscan osteoarthritis hand index: an evaluation of reliability, validity and responsiveness. Osteoarthr Cartil. 2002b;10:863–9.CrossRefPubMed
64.
Bellamy N, Haraoui B, Buchbinder R, Hall S, Muirden K, Hobby K, Roth J, MacDermid JC, Soucy E, Gerecz-Simon E, Flynn J, Campbell J. Development of a disease-specific health status measure for hand osteoarthritis clinical trials: assessment of the symptom dimensionality. J Rheumatol. 1996;5:106S.
65.
Sallis JF, Haskell WL, Wood PD, Fortmann SP, Rogers T, Blair SN, Paffenbarger RS. Physical activity assessment methodology in the Five-City project. Am J Epidemiol. 1985;121(1):91–106.CrossRefPubMed
66.
Sallis JF, Buono MJ, Roby JJ, Micale FG, Nelson JA. Seven-day physical activity recall. Med Sci Sports Exerc. 1997;29:89–103.
67.
Hayden-Wade HA, Coleman KJ, Sallis JF, Armstrong C. Validation of the telephone and in-person interview versions of the 7-day PAR. Med Sci Sports Exerc. 2003;35(5):801–9.CrossRefPubMed
68.
Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQoL group. Ann Med. 2001;33(5):337–43.CrossRefPubMed
69.
Dreiser RL, Maheu E, Guillou GB, Caspard H, Grouin JM. Validation of an algofunctional index for osteoarthritis of the hand. Rev Rhum Engl Ed. 1995;62(Suppl 1):43S–53S.PubMed
70.
71.
Tukey J. comparing individual means in the analysis of variance. Biometrics. 1949;5(2):99–114. JSTOR 3001913CrossRefPubMed
72.
Cipolat L, Loeb O, Latarche C, Pape E, Gillet P, Petitpain N. Acetaminophen: knowledge, use and overdose risk in urban patients consulting their general practitioner. A prospective, descriptive and transversal study Thérapie. 2017;20(17):30036–7. https://​doi.​org/​10.​1016/​j.​therap.​2016.​12.​012. [Epub ahead of print] pii: S0040-5957
73.
Kloppenburg M, Bøyesen P, Visser AW, Haugen IK, Boers M, Boonen A, Conaghan PG, et al. Report from the OMERACT hand osteoarthritis working group: set of Core domains and preliminary set of instruments for use in clinical trials and observational studies. J Rheumatol. 2015;42(11):2190–7.
74.
75.
Prodinger B, Stamm T, Peterson D, Stucki G, Tennant A. On behalf of the international classification of functioning, disability, and health info network. Toward a Standardized Reporting of Outcomes in Hand Osteoarthritis: Developing a Common Metric of Outcome Measures Commonly Used to Assess Functioning Arthritis Care & Research. 2016;68(8):1115–27. https://​doi.​org/​10.​1002/​acr.​22816.
76.
Taylor AM, Phillips K, Kushang K, Patel V. Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations. Pain. 2016;157:1836–50.CrossRefPubMed
77.
Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, Kerns RD, Stucki G, Allen RR, Bellamy N, Carr DB, Chandler J, Cowan P, Dionne R, Galer BS, Hertz S, Jadad AR, Kramer LD, Manning DC, Martin S, McCormick CG, McDermott MP, McGrath P, Quessy S, Rappaport BA, Robbins W, Robinson JP, Rothman M, Royal MA, Simon L, Stauffer JW, Stein W, Tollett J, Wernicke J, Witter J. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113:9–19.CrossRefPubMed
78.
Hartley S, Garland S, Young E, Bennell KL, Tay I, Gorelik A, Wark JD. A comparison of self-reported and objective physical activity measures in young Australian women. JMIR Public Health Surveill. 2015;1(2):e14.CrossRefPubMedPubMedCentral
79.
Marchand S. Le phénomène de la douleur. Les Éditions de la Chenelière inc: Montréal; 2009.
Metadata
Title
The knitting community-based trial for older women with osteoarthritis of the hands: design and rationale of a randomized controlled trial
Authors
Paulette Guitard
Lucie Brosseau
George A. Wells
Nicole Paquet
Gail Paterson
Karine Toupin-April
Sabrina Cavallo
Sibel Z. Aydin
Guillaume Léonard
Gino De Angelis
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2018
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-018-1965-2

Other articles of this Issue 1/2018

BMC Musculoskeletal Disorders 1/2018 Go to the issue

Research article

Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis

Research article

Weight bearing versus non-weight bearing ankle dorsiflexion measurement in people with diabetes: a cross sectional study

Research article

Postoperative function recovery in patients with endoprosthetic knee replacement for bone tumour: an observational study

Research article

Interview based malnutrition assessment can predict adverse events within 6 months after primary and revision arthroplasty – a prospective observational study of 351 patients

Research article

The impact of thigh and shank marker quantity on lower extremity kinematics using a constrained model

Research article

Single cut distal femoral osteotomy for correction of femoral torsion and valgus malformity in patellofemoral malalignment - proof of application of new trigonometrical calculations and 3D-printed cutting guides