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Published in: BMC Musculoskeletal Disorders 1/2017

Open Access 01-12-2017 | Research article

Impact of midfoot and Hindfoot involvement on functional disability in Korean patients with rheumatoid arthritis

Authors: Hye-Jin Jeong, Il Woong Sohn, Dam Kim, Soo-Kyung Cho, Si-Bog Park, Il-Hoon Sung, Yoon-Kyoung Sung

Published in: BMC Musculoskeletal Disorders | Issue 1/2017

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Abstract

Background

Foot involvement in rheumatoid arthritis (RA) patients has been reported to severely affect functional capacity and quality of life. We aimed to determine the impact of midfoot and hindfoot involvement on functional disability in Korean patients with RA.

Methods

We evaluated the RA involvement and deformity of three regions of the foot (forefoot, midfoot and hindfoot) and ankle using conventional radiography in Korean patients with RA. We compared the clinical features between RA patients with and without foot or ankle involvement. Using multivariable logistic regression analyses, the impact of midfoot or hindfoot involvement on functional disability in RA patients was evaluated.

Results

Overall, 120 patients with a median age of 48.0 [interquartile range (IQR), 37–56] years and median disease duration of 58.0 (IQR, 10–89) months were included. The prevalence of foot or ankle RA involvement was 74 (61.7%). The number of patients with forefoot, midfoot, hindfoot and ankle involvement was 32 (43.2%), 24 (32.4%), 46 (62.2%) and 4 (5.4%), respectively. Compared to patients without foot or ankle involvement those with such involvement had greater disease activity and functional disability, more of them were treated with biologic agents, and they had a lower health-related quality of life. After adjusting for potential confounders, hindfoot involvement was associated with a higher degree of functional disability. However, walking difficulty was more associated with midfoot involvement rather than with involvement in other regions.

Conclusions

In Korean patients with RA, hindfoot involvement is associated with functional disability and midfoot involvement affects walking.
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Literature
1.
go back to reference van der Leeden M, Steultjens M, Dekker JH, Prins AP, Dekker J. Forefoot joint damage, pain and disability in rheumatoid arthritis patients with foot complaints: the role of plantar pressure and gait characteristics. Rheumatology (Oxford). 2006;45(4):465–9.CrossRef van der Leeden M, Steultjens M, Dekker JH, Prins AP, Dekker J. Forefoot joint damage, pain and disability in rheumatoid arthritis patients with foot complaints: the role of plantar pressure and gait characteristics. Rheumatology (Oxford). 2006;45(4):465–9.CrossRef
2.
go back to reference Otter SJ, Lucas K, Springett K, Moore A, Davies K, Young A, et al. Comparison of foot pain and foot care among rheumatoid arthritis patients taking and not taking anti-TNFα therapy: an epidemiological study. Rheumatol Int. 2010;31(11):1515–9.CrossRefPubMed Otter SJ, Lucas K, Springett K, Moore A, Davies K, Young A, et al. Comparison of foot pain and foot care among rheumatoid arthritis patients taking and not taking anti-TNFα therapy: an epidemiological study. Rheumatol Int. 2010;31(11):1515–9.CrossRefPubMed
3.
go back to reference Hamamoto Y, Ito H, Furu M, Hashimoto M, Fujii T, Ishikawa M, et al. Serological and progression differences of joint destruction in the wrist and the feet in rheumatoid arthritis - a cross-sectional cohort study. PLoS One. 2015;10(8):e0136611.CrossRefPubMedPubMedCentral Hamamoto Y, Ito H, Furu M, Hashimoto M, Fujii T, Ishikawa M, et al. Serological and progression differences of joint destruction in the wrist and the feet in rheumatoid arthritis - a cross-sectional cohort study. PLoS One. 2015;10(8):e0136611.CrossRefPubMedPubMedCentral
5.
go back to reference Rojas-Villarraga A, Bayona J, Zuluaga N, Mejia S, Hincapie ME, Anaya JM. The impact of rheumatoid foot on disability in Colombian patients with rheumatoid arthritis. BMC Musculoskelet Disord. 2009;10:67.CrossRefPubMedPubMedCentral Rojas-Villarraga A, Bayona J, Zuluaga N, Mejia S, Hincapie ME, Anaya JM. The impact of rheumatoid foot on disability in Colombian patients with rheumatoid arthritis. BMC Musculoskelet Disord. 2009;10:67.CrossRefPubMedPubMedCentral
6.
go back to reference Matsumoto T, Nakamura I, Miura A, Momoyama G, Ito K. Radiologic patterning of joint damage to the foot in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2014;66(4):499–507.CrossRef Matsumoto T, Nakamura I, Miura A, Momoyama G, Ito K. Radiologic patterning of joint damage to the foot in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2014;66(4):499–507.CrossRef
7.
go back to reference Bal A, Aydog E, Aydog ST, Cakci A. Foot deformities in rheumatoid arthritis and relevance of foot function index. Clin Rheumatol. 2006;25(5):671–5.CrossRefPubMed Bal A, Aydog E, Aydog ST, Cakci A. Foot deformities in rheumatoid arthritis and relevance of foot function index. Clin Rheumatol. 2006;25(5):671–5.CrossRefPubMed
8.
go back to reference Helliwell P, Siddle H, Redmond A. The foot and ankle in rheumatology. Arthritis Res. 2011;6(8):1–11. Helliwell P, Siddle H, Redmond A. The foot and ankle in rheumatology. Arthritis Res. 2011;6(8):1–11.
9.
go back to reference Prevoo ML, van’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 1995;38(1):44–8.CrossRefPubMed Prevoo ML, van’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 1995;38(1):44–8.CrossRefPubMed
10.
go back to reference Landewe R, van der Heijde D, van der Linden S, Boers M. Twenty-eight-joint counts invalidate the DAS28 remission definition owing to the omission of the lower extremity joints: a comparison with the original DAS remission. Ann Rheum Dis. 2006;65(5):637–41.CrossRefPubMed Landewe R, van der Heijde D, van der Linden S, Boers M. Twenty-eight-joint counts invalidate the DAS28 remission definition owing to the omission of the lower extremity joints: a comparison with the original DAS remission. Ann Rheum Dis. 2006;65(5):637–41.CrossRefPubMed
11.
go back to reference Wechalekar MD, Lester S, Proudman SM, Cleland LG, Whittle SL, Rischmueller M, et al. Active foot synovitis in patients with rheumatoid arthritis: applying clinical criteria for disease activity and remission may result in underestimation of foot joint involvement. Arthritis Rheum. 2012;64(5):1316–22.CrossRefPubMed Wechalekar MD, Lester S, Proudman SM, Cleland LG, Whittle SL, Rischmueller M, et al. Active foot synovitis in patients with rheumatoid arthritis: applying clinical criteria for disease activity and remission may result in underestimation of foot joint involvement. Arthritis Rheum. 2012;64(5):1316–22.CrossRefPubMed
12.
go back to reference Patel A, Rao S, Nawoczenski D, Flemister AS, DiGiovanni B, Baumhauer JF. Midfoot arthritis. J Am Acad Orthop Surg. 2010;18(7):417–25.CrossRefPubMed Patel A, Rao S, Nawoczenski D, Flemister AS, DiGiovanni B, Baumhauer JF. Midfoot arthritis. J Am Acad Orthop Surg. 2010;18(7):417–25.CrossRefPubMed
13.
go back to reference Verhoeven N, Vandeputte G. Midfoot arthritis: diagnosis and treatment. Foot Ankle Surg. 2012;18(4):255–62.CrossRefPubMed Verhoeven N, Vandeputte G. Midfoot arthritis: diagnosis and treatment. Foot Ankle Surg. 2012;18(4):255–62.CrossRefPubMed
14.
go back to reference V.Abdo R, Iorio LJ. Rheumatoid arthritis of the foot and ankle. J m Acad Orthop Surg. 1994;2(6):326–33.CrossRef V.Abdo R, Iorio LJ. Rheumatoid arthritis of the foot and ankle. J m Acad Orthop Surg. 1994;2(6):326–33.CrossRef
15.
go back to reference Chan PS, Kong KO. Natural history and imaging of subtalar and midfoot joint disease in rheumatoid arthritis. Int J Rheum Dis. 2013;16(1):14–8.CrossRefPubMed Chan PS, Kong KO. Natural history and imaging of subtalar and midfoot joint disease in rheumatoid arthritis. Int J Rheum Dis. 2013;16(1):14–8.CrossRefPubMed
16.
go back to reference Keenan MA, Peabody TD, Gronley JK, Perry J. Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis. J Bone and Joint Surg Am. 1991;73(2):237–47.CrossRef Keenan MA, Peabody TD, Gronley JK, Perry J. Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis. J Bone and Joint Surg Am. 1991;73(2):237–47.CrossRef
17.
go back to reference Mann RA, Horton GA. Management of the foot and ankle in rheumatoid arthritis. Rheum Dis Clin N Am. 1996;22(3):457–76.CrossRef Mann RA, Horton GA. Management of the foot and ankle in rheumatoid arthritis. Rheum Dis Clin N Am. 1996;22(3):457–76.CrossRef
18.
go back to reference Jaakkola JI, Mann RA. A review of rheumatoid arthritis affecting the foot and ankle. Foot Ankle Int. 2004;25(12):866–74.CrossRefPubMed Jaakkola JI, Mann RA. A review of rheumatoid arthritis affecting the foot and ankle. Foot Ankle Int. 2004;25(12):866–74.CrossRefPubMed
19.
go back to reference Grondal L, Tengstrand B, Nordmark B, Wretenberg P, Stark A. The foot: still the most important reason for walking incapacity in rheumatoid arthritis: distribution of symptomatic joints in 1,000 RA patients. Acta Orthop. 2008;79(2):257–61.CrossRefPubMed Grondal L, Tengstrand B, Nordmark B, Wretenberg P, Stark A. The foot: still the most important reason for walking incapacity in rheumatoid arthritis: distribution of symptomatic joints in 1,000 RA patients. Acta Orthop. 2008;79(2):257–61.CrossRefPubMed
20.
go back to reference van der Leeden M, Steultjens MP, Ursum J, Dahmen R, Roorda LD, Schaardenburg DV, et al. Prevalence and course of forefoot impairments and walking disability in the first eight years of rheumatoid arthritis. Arthritis Rheum. 2008;59(11):1596–602.CrossRefPubMed van der Leeden M, Steultjens MP, Ursum J, Dahmen R, Roorda LD, Schaardenburg DV, et al. Prevalence and course of forefoot impairments and walking disability in the first eight years of rheumatoid arthritis. Arthritis Rheum. 2008;59(11):1596–602.CrossRefPubMed
21.
go back to reference Otter SJ, Lucas K, Springett K, Moore A, Davies K, Cheek L, et al. Foot pain in rheumatoid arthritis prevalence, risk factors and management: an epidemiological study. Clin Rheumatol. 2010;29(3):255–71.CrossRefPubMed Otter SJ, Lucas K, Springett K, Moore A, Davies K, Cheek L, et al. Foot pain in rheumatoid arthritis prevalence, risk factors and management: an epidemiological study. Clin Rheumatol. 2010;29(3):255–71.CrossRefPubMed
22.
go back to reference Ohly NE, Breusch SJ. Additive hindfoot arthrodesis for rheumatoid hindfoot disease: a clinical study of patient outcomes and satisfaction. Clin Rheumatol. 2013;32(12):1777–82.CrossRefPubMed Ohly NE, Breusch SJ. Additive hindfoot arthrodesis for rheumatoid hindfoot disease: a clinical study of patient outcomes and satisfaction. Clin Rheumatol. 2013;32(12):1777–82.CrossRefPubMed
23.
go back to reference Cracchiolo A 3rd. Rheumatoid arthritis. Hindfoot disease. Cli Orthop Relat Res. 1997;340:58–68.CrossRef Cracchiolo A 3rd. Rheumatoid arthritis. Hindfoot disease. Cli Orthop Relat Res. 1997;340:58–68.CrossRef
24.
go back to reference Soo-Kyung C, Dam K, Jeongim C, Seung L, Ga Eun B, Hyeon Kyung K, et al. Impact of patient education on the satisfaction of rheumatoid arthritis patients: a randomized trial of nurse-led versus medical Docter-led education. J Rheum Dis. 2016;23(2):109–17.CrossRef Soo-Kyung C, Dam K, Jeongim C, Seung L, Ga Eun B, Hyeon Kyung K, et al. Impact of patient education on the satisfaction of rheumatoid arthritis patients: a randomized trial of nurse-led versus medical Docter-led education. J Rheum Dis. 2016;23(2):109–17.CrossRef
25.
go back to reference Kim M-H, Cho Y-S, Uhm W-S, Kim S, Bae S-C. Cross-cultural adaptation and validation of the Korean version of the EQ-5D in patients with rheumatic diseases. Qual Life Res. 2005;14(5):1401–6.CrossRefPubMed Kim M-H, Cho Y-S, Uhm W-S, Kim S, Bae S-C. Cross-cultural adaptation and validation of the Korean version of the EQ-5D in patients with rheumatic diseases. Qual Life Res. 2005;14(5):1401–6.CrossRefPubMed
26.
go back to reference Bae SC, Cook EF, Kim SY. Psychometric evaluation of a Korean health assessment questionnaire for clinical research. J Rheumatol. 1998;25(10):1975–9.PubMed Bae SC, Cook EF, Kim SY. Psychometric evaluation of a Korean health assessment questionnaire for clinical research. J Rheumatol. 1998;25(10):1975–9.PubMed
27.
28.
go back to reference Borman P, Ayhan F, Tuncay F, Sahin M. Foot problems in a group of patients with rheumatoid arthritis: an unmet need for foot care. Open Rheumatology J. 2012;6:290–5.CrossRef Borman P, Ayhan F, Tuncay F, Sahin M. Foot problems in a group of patients with rheumatoid arthritis: an unmet need for foot care. Open Rheumatology J. 2012;6:290–5.CrossRef
29.
go back to reference van der Leeden M, Steultjens M, Dekker JH, Prins AP, Dekker J. The relationship of disease duration to foot function, pain and disability in rheumatoid arthritis patients with foot complaints. Clin Exp Rheumatol. 2007;25(2):275–80.PubMed van der Leeden M, Steultjens M, Dekker JH, Prins AP, Dekker J. The relationship of disease duration to foot function, pain and disability in rheumatoid arthritis patients with foot complaints. Clin Exp Rheumatol. 2007;25(2):275–80.PubMed
30.
go back to reference Bouysset M, Tebib J, Noel E, Tavernier T, Miossec P, Vianey JC, et al. Rheumatoid flat foot and deformity of the first ray. J Rheumatol. 2002;29(5):903–5.PubMed Bouysset M, Tebib J, Noel E, Tavernier T, Miossec P, Vianey JC, et al. Rheumatoid flat foot and deformity of the first ray. J Rheumatol. 2002;29(5):903–5.PubMed
31.
go back to reference Otter SJ, Lucas K, Springett K, Moore A, Davies K, Young A, et al. Comparison of foot pain and foot care among rheumatoid arthritis patients taking and not taking anti-TNFalpha therapy: an epidemiological study. Rheumatol Int. 2011;31(11):1515–9.CrossRefPubMed Otter SJ, Lucas K, Springett K, Moore A, Davies K, Young A, et al. Comparison of foot pain and foot care among rheumatoid arthritis patients taking and not taking anti-TNFalpha therapy: an epidemiological study. Rheumatol Int. 2011;31(11):1515–9.CrossRefPubMed
32.
go back to reference Rao S, Nawoczenski DA, Baumhauer JF. Midfoot arthritis: nonoperative options and decision making for fusion. Tech Foot Ankle Surg. 2008;7(3):188–95.CrossRef Rao S, Nawoczenski DA, Baumhauer JF. Midfoot arthritis: nonoperative options and decision making for fusion. Tech Foot Ankle Surg. 2008;7(3):188–95.CrossRef
Metadata
Title
Impact of midfoot and Hindfoot involvement on functional disability in Korean patients with rheumatoid arthritis
Authors
Hye-Jin Jeong
Il Woong Sohn
Dam Kim
Soo-Kyung Cho
Si-Bog Park
Il-Hoon Sung
Yoon-Kyoung Sung
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2017
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-017-1726-7

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