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Published in: BMC Musculoskeletal Disorders 1/2017

Open Access 01-12-2017 | Research article

Leg pain location and neurological signs relate to outcomes in primary care patients with low back pain

Authors: Lisbeth Hartvigsen, Lise Hestbaek, Charlotte Lebouef-Yde, Werner Vach, Alice Kongsted

Published in: BMC Musculoskeletal Disorders | Issue 1/2017

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Abstract

Background

Low back pain (LBP) patients with related leg pain and signs of nerve root involvement are considered to have a worse prognosis than patients with LBP alone. However, it is unclear whether leg pain location above or below the knee and the presence of neurological signs are important in primary care patients. The objectives of this study were to explore whether the four Quebec Task Force categories (QTFC) based on the location of pain and on neurological signs have different characteristics at the time of care seeking, whether these QTFC are associated with outcome, and if so whether there is an obvious ranking of the four QTFC on the severity of outcomes.

Method

Adult patients seeking care for LBP in chiropractic or general practice were classified into the four QTFC based on self-reported information and clinical findings. Analyses were performed to test the associations between the QTFC and baseline characteristics as well as the outcomes global perceived effect and activity limitation after 2 weeks, 3 months, and 1 year and also 1-year trajectories of LBP intensity.

Results

The study comprised 1271 patients; 947 from chiropractic practice and 324 from general practice. The QTFC at presentation were statistically significantly associated with most of the baseline characteristics, with activity limitation at all follow-up time points, with global perceived effect at 2 weeks but not 3 months and 1 year, and with trajectories of LBP. Severity of outcomes in the QTFC increased from LBP alone, across LBP with leg pain above the knee and below the knee to LBP with nerve root involvement. However, the variation within the categories was considerable.

Conclusion

The QTFC identify different LBP subgroups at baseline and there is a consistent ranking of the four categories with respect to outcomes. The differences between outcomes appear to be large enough for the QTFC to be useful for clinicians in the communication with patients. However, due to variation of outcomes within each category individuals’ outcome cannot be precisely predicted from the QTFC alone. It warrants further investigation to find out if the QTFC can improve existing prediction tools and guide treatment decisions.
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Literature
1.
go back to reference Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2163–96.CrossRefPubMed Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2163–96.CrossRefPubMed
3.
go back to reference Flachs EM EL, Koch MB, Ryd JT, Dibba E, Skov-Ettrup L, Juel K. Sygdomsbyrden i Danmark – sygdomme. In: Statens Institut for Folkesundhed, Syddansk Universitet. København: Sundhedsstyrelsen; 2015. Flachs EM EL, Koch MB, Ryd JT, Dibba E, Skov-Ettrup L, Juel K. Sygdomsbyrden i Danmark – sygdomme. In: Statens Institut for Folkesundhed, Syddansk Universitet. København: Sundhedsstyrelsen; 2015.
4.
go back to reference van Tulder M, Becker A, Bekkering T, Breen A, del Real MT, Hutchinson A, Koes B, Laerum E, Malmivaara A. Chapter 3. European guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J. 2006;15 Suppl 2:S169–191.CrossRefPubMedPubMedCentral van Tulder M, Becker A, Bekkering T, Breen A, del Real MT, Hutchinson A, Koes B, Laerum E, Malmivaara A. Chapter 3. European guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J. 2006;15 Suppl 2:S169–191.CrossRefPubMedPubMedCentral
5.
go back to reference Karayannis NV, Jull GA, Hodges PW. Physiotherapy movement based classification approaches to low back pain: comparison of subgroups through review and developer/expert survey. BMC Musculoskelet Disord. 2012;13:24.CrossRefPubMedPubMedCentral Karayannis NV, Jull GA, Hodges PW. Physiotherapy movement based classification approaches to low back pain: comparison of subgroups through review and developer/expert survey. BMC Musculoskelet Disord. 2012;13:24.CrossRefPubMedPubMedCentral
6.
go back to reference Fairbank J, Gwilym SE, France JC, Daffner SD, Dettori J, Hermsmeyer J, Andersson G. The role of classification of chronic low back pain. Spine. 2011;36(21 Suppl):S19–42.CrossRefPubMed Fairbank J, Gwilym SE, France JC, Daffner SD, Dettori J, Hermsmeyer J, Andersson G. The role of classification of chronic low back pain. Spine. 2011;36(21 Suppl):S19–42.CrossRefPubMed
7.
go back to reference O SW. Scientific approach to the assessment and management of activity-related spinal disorders. A monograph for clinicians. Report of the Quebec Task Force on Spinal Disorders. Spine. 1987;12(7 Suppl):S1-59. O SW. Scientific approach to the assessment and management of activity-related spinal disorders. A monograph for clinicians. Report of the Quebec Task Force on Spinal Disorders. Spine. 1987;12(7 Suppl):S1-59.
8.
go back to reference Atlas SJ, Deyo RA, Patrick DL, Convery K, Keller RB, Singer DE. The Quebec Task Force classification for spinal disorders and the severity, treatment, and outcomes of sciatica and lumbar spinal stenosis. Spine. 1996;21(24):2885–92.CrossRefPubMed Atlas SJ, Deyo RA, Patrick DL, Convery K, Keller RB, Singer DE. The Quebec Task Force classification for spinal disorders and the severity, treatment, and outcomes of sciatica and lumbar spinal stenosis. Spine. 1996;21(24):2885–92.CrossRefPubMed
9.
go back to reference Loisel P, Vachon B, Lemaire J, Durand MJ, Poitras S, Stock S, Tremblay C. Discriminative and predictive validity assessment of the quebec task force classification. Spine. 2002;27(8):851–7.CrossRefPubMed Loisel P, Vachon B, Lemaire J, Durand MJ, Poitras S, Stock S, Tremblay C. Discriminative and predictive validity assessment of the quebec task force classification. Spine. 2002;27(8):851–7.CrossRefPubMed
10.
go back to reference Werneke MW, Hart DL. Categorizing patients with occupational low back pain by use of the Quebec Task Force Classification system versus pain pattern classification procedures: discriminant and predictive validity. Phys Ther. 2004;84(3):243–54.PubMed Werneke MW, Hart DL. Categorizing patients with occupational low back pain by use of the Quebec Task Force Classification system versus pain pattern classification procedures: discriminant and predictive validity. Phys Ther. 2004;84(3):243–54.PubMed
11.
go back to reference Selim AJ, Ren XS, Fincke G, Deyo RA, Rogers W, Miller D, Linzer M, Kazis L. The importance of radiating leg pain in assessing health outcomes among patients with low back pain. Results from the Veterans Health Study. Spine. 1998;23(4):470–4.CrossRefPubMed Selim AJ, Ren XS, Fincke G, Deyo RA, Rogers W, Miller D, Linzer M, Kazis L. The importance of radiating leg pain in assessing health outcomes among patients with low back pain. Results from the Veterans Health Study. Spine. 1998;23(4):470–4.CrossRefPubMed
12.
go back to reference Kongsted A, Kent P, Albert H, Jensen TS, Manniche C. Patients with low back pain differ from those who also have leg pain or signs of nerve root involvement - a cross-sectional study. BMC Musculoskelet Disord. 2012;13:236.CrossRefPubMedPubMedCentral Kongsted A, Kent P, Albert H, Jensen TS, Manniche C. Patients with low back pain differ from those who also have leg pain or signs of nerve root involvement - a cross-sectional study. BMC Musculoskelet Disord. 2012;13:236.CrossRefPubMedPubMedCentral
13.
go back to reference Kongsted A, Kent P, Jensen TS, Albert H, Manniche C. Prognostic implications of the Quebec Task Force classification of back-related leg pain: an analysis of longitudinal routine clinical data. BMC Musculoskelet Disord. 2013;14:171.CrossRefPubMedPubMedCentral Kongsted A, Kent P, Jensen TS, Albert H, Manniche C. Prognostic implications of the Quebec Task Force classification of back-related leg pain: an analysis of longitudinal routine clinical data. BMC Musculoskelet Disord. 2013;14:171.CrossRefPubMedPubMedCentral
14.
go back to reference Hider SL, Whitehurst DG, Thomas E, Foster NE. Pain location matters: the impact of leg pain on health care use, work disability and quality of life in patients with low back pain. Eur Spine J. 2015;24(3):444–51.CrossRefPubMed Hider SL, Whitehurst DG, Thomas E, Foster NE. Pain location matters: the impact of leg pain on health care use, work disability and quality of life in patients with low back pain. Eur Spine J. 2015;24(3):444–51.CrossRefPubMed
15.
go back to reference Hill JC, Konstantinou K, Egbewale BE, Dunn KM, Lewis M, van der Windt D. Clinical outcomes among low back pain consulters with referred leg pain in primary care. Spine. 2011;36(25):2168–75.CrossRefPubMed Hill JC, Konstantinou K, Egbewale BE, Dunn KM, Lewis M, van der Windt D. Clinical outcomes among low back pain consulters with referred leg pain in primary care. Spine. 2011;36(25):2168–75.CrossRefPubMed
16.
go back to reference Konstantinou K, Hider SL, Jordan JL, Lewis M, Dunn KM, Hay EM. The impact of low back-related leg pain on outcomes as compared with low back pain alone: a systematic review of the literature. Clin J Pain. 2013;29(7):644–54.CrossRefPubMed Konstantinou K, Hider SL, Jordan JL, Lewis M, Dunn KM, Hay EM. The impact of low back-related leg pain on outcomes as compared with low back pain alone: a systematic review of the literature. Clin J Pain. 2013;29(7):644–54.CrossRefPubMed
17.
go back to reference Ashworth J, Konstantinou K, Dunn KM. Prognostic factors in non-surgically treated sciatica: a systematic review. BMC Musculoskelet Disord. 2011;12:208.CrossRefPubMedPubMedCentral Ashworth J, Konstantinou K, Dunn KM. Prognostic factors in non-surgically treated sciatica: a systematic review. BMC Musculoskelet Disord. 2011;12:208.CrossRefPubMedPubMedCentral
18.
go back to reference Koes BW, van Tulder M, Lin CW, Macedo LG, McAuley J, Maher C. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. Eur Spine J. 2010;19(12):2075–94.CrossRefPubMedPubMedCentral Koes BW, van Tulder M, Lin CW, Macedo LG, McAuley J, Maher C. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. Eur Spine J. 2010;19(12):2075–94.CrossRefPubMedPubMedCentral
19.
go back to reference Hestbaek L, Munck A, Hartvigsen L, Jarbol DE, Sondergaard J, Kongsted A. Low back pain in primary care: a description of 1250 patients with low back pain in danish general and chiropractic practice. Int J Fam Med. 2014;2014:106102. Hestbaek L, Munck A, Hartvigsen L, Jarbol DE, Sondergaard J, Kongsted A. Low back pain in primary care: a description of 1250 patients with low back pain in danish general and chiropractic practice. Int J Fam Med. 2014;2014:106102.
20.
go back to reference Kongsted A, Kent P, Hestbaek L, Vach W. Patients with low back pain had distinct clinical course patterns that were typically neither complete recovery nor constant pain. A latent class analysis of longitudinal data. Spine J. 2015;15(5):885–94.CrossRefPubMed Kongsted A, Kent P, Hestbaek L, Vach W. Patients with low back pain had distinct clinical course patterns that were typically neither complete recovery nor constant pain. A latent class analysis of longitudinal data. Spine J. 2015;15(5):885–94.CrossRefPubMed
21.
go back to reference Eirikstoft H, Kongsted A. Patient characteristics in low back pain subgroups based on an existing classification system. A descriptive cohort study in chiropractic practice. Man Ther. 2014;19(1):65–71.CrossRefPubMed Eirikstoft H, Kongsted A. Patient characteristics in low back pain subgroups based on an existing classification system. A descriptive cohort study in chiropractic practice. Man Ther. 2014;19(1):65–71.CrossRefPubMed
22.
go back to reference Kent P, Lauridsen HH. Managing missing scores on the Roland Morris Disability Questionnaire. Spine. 2011;36(22):1878–84.CrossRefPubMed Kent P, Lauridsen HH. Managing missing scores on the Roland Morris Disability Questionnaire. Spine. 2011;36(22):1878–84.CrossRefPubMed
23.
go back to reference Jensen MP, Miller L, Fisher LD. Assessment of pain during medical procedures: a comparison of three scales. Clin J Pain. 1998;14(4):343–9.CrossRefPubMed Jensen MP, Miller L, Fisher LD. Assessment of pain during medical procedures: a comparison of three scales. Clin J Pain. 1998;14(4):343–9.CrossRefPubMed
24.
go back to reference Kongsted A, Vach W, Axo M, Bech RN, Hestbaek L. Expectation of recovery from low back pain: a longitudinal cohort study investigating patient characteristics related to expectations and the association between expectations and 3-month outcome. Spine. 2014;39(1):81–90.CrossRefPubMed Kongsted A, Vach W, Axo M, Bech RN, Hestbaek L. Expectation of recovery from low back pain: a longitudinal cohort study investigating patient characteristics related to expectations and the association between expectations and 3-month outcome. Spine. 2014;39(1):81–90.CrossRefPubMed
25.
go back to reference Bech P, Rasmussen NA, Olsen LR, Noerholm V, Abildgaard W. The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity. J Affect Disord. 2001;66(2–3):159–64.CrossRefPubMed Bech P, Rasmussen NA, Olsen LR, Noerholm V, Abildgaard W. The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity. J Affect Disord. 2001;66(2–3):159–64.CrossRefPubMed
26.
go back to reference Waddell G, Newton M, Henderson I, Somerville D, Main CJ. A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain. 1993;52(2):157–68.CrossRefPubMed Waddell G, Newton M, Henderson I, Somerville D, Main CJ. A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain. 1993;52(2):157–68.CrossRefPubMed
27.
go back to reference Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33(5):337–43.CrossRefPubMed Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33(5):337–43.CrossRefPubMed
28.
go back to reference Hill JC, Dunn KM, Lewis M, Mullis R, Main CJ, Foster NE, Hay EM. A primary care back pain screening tool: identifying patient subgroups for initial treatment. Arthritis Rheum. 2008;59(5):632–41.CrossRefPubMed Hill JC, Dunn KM, Lewis M, Mullis R, Main CJ, Foster NE, Hay EM. A primary care back pain screening tool: identifying patient subgroups for initial treatment. Arthritis Rheum. 2008;59(5):632–41.CrossRefPubMed
29.
go back to reference Kamper SJ, Ostelo RW, Knol DL, Maher CG, de Vet HC, Hancock MJ. Global Perceived Effect scales provided reliable assessments of health transition in people with musculoskeletal disorders, but ratings are strongly influenced by current status. J Clin Epidemiol. 2010;63(7):760–6. e761.CrossRefPubMed Kamper SJ, Ostelo RW, Knol DL, Maher CG, de Vet HC, Hancock MJ. Global Perceived Effect scales provided reliable assessments of health transition in people with musculoskeletal disorders, but ratings are strongly influenced by current status. J Clin Epidemiol. 2010;63(7):760–6. e761.CrossRefPubMed
30.
go back to reference Axen I, Bodin L, Bergstrom G, Halasz L, Lange F, Lovgren PW, Rosenbaum A, Leboeuf-Yde C, Jensen I. The use of weekly text messaging over 6 months was a feasible method for monitoring the clinical course of low back pain in patients seeking chiropractic care. J Clin Epidemiol. 2012;65(4):454–61.CrossRefPubMed Axen I, Bodin L, Bergstrom G, Halasz L, Lange F, Lovgren PW, Rosenbaum A, Leboeuf-Yde C, Jensen I. The use of weekly text messaging over 6 months was a feasible method for monitoring the clinical course of low back pain in patients seeking chiropractic care. J Clin Epidemiol. 2012;65(4):454–61.CrossRefPubMed
31.
go back to reference Kongsted A, Kent P, Axen I, Downie AS, Dunn KM. What have we learned from ten years of trajectory research in low back pain? BMC Musculoskelet Disord. 2016;17:220.CrossRefPubMedPubMedCentral Kongsted A, Kent P, Axen I, Downie AS, Dunn KM. What have we learned from ten years of trajectory research in low back pain? BMC Musculoskelet Disord. 2016;17:220.CrossRefPubMedPubMedCentral
32.
go back to reference Bombardier C, Hayden J, Beaton DE. Minimal clinically important difference. Low back pain: outcome measures. J Rheumatol. 2001;28(2):431–8.PubMed Bombardier C, Hayden J, Beaton DE. Minimal clinically important difference. Low back pain: outcome measures. J Rheumatol. 2001;28(2):431–8.PubMed
33.
go back to reference Ostelo RW, Deyo RA, Stratford P, Waddell G, Croft P, Von Korff M, Bouter LM, de Vet HC. Interpreting change scores for pain and functional status in low back pain: towards international consensus regarding minimal important change. Spine. 2008;33(1):90–4.CrossRefPubMed Ostelo RW, Deyo RA, Stratford P, Waddell G, Croft P, Von Korff M, Bouter LM, de Vet HC. Interpreting change scores for pain and functional status in low back pain: towards international consensus regarding minimal important change. Spine. 2008;33(1):90–4.CrossRefPubMed
34.
go back to reference Royston PSW. A new measure of prognostic separation in survival data. Stat Med. 2004;23(5):723–48.CrossRefPubMed Royston PSW. A new measure of prognostic separation in survival data. Stat Med. 2004;23(5):723–48.CrossRefPubMed
35.
go back to reference Axen I, Leboeuf-Yde C. Trajectories of low back pain. Best Pract Res Clin Rheumatol. 2013;27(5):601–12.CrossRefPubMed Axen I, Leboeuf-Yde C. Trajectories of low back pain. Best Pract Res Clin Rheumatol. 2013;27(5):601–12.CrossRefPubMed
36.
go back to reference Dunn KM, Hestbaek L, Cassidy JD. Low back pain across the life course. Best Pract Res Clin Rheumatol. 2013;27(5):591–600.CrossRefPubMed Dunn KM, Hestbaek L, Cassidy JD. Low back pain across the life course. Best Pract Res Clin Rheumatol. 2013;27(5):591–600.CrossRefPubMed
37.
go back to reference Lemeunier N, Leboeuf-Yde C, Gagey O. The natural course of low back pain: a systematic critical literature review. Chiropr Man Ther. 2012;20(1):33.CrossRef Lemeunier N, Leboeuf-Yde C, Gagey O. The natural course of low back pain: a systematic critical literature review. Chiropr Man Ther. 2012;20(1):33.CrossRef
38.
go back to reference Leboeuf-Yde C, Lemeunier N, Wedderkopp N, Kjaer P. Evidence-based classification of low back pain in the general population: one-year data collected with SMS Track. Chiropr Man Ther. 2013;21:30.CrossRef Leboeuf-Yde C, Lemeunier N, Wedderkopp N, Kjaer P. Evidence-based classification of low back pain in the general population: one-year data collected with SMS Track. Chiropr Man Ther. 2013;21:30.CrossRef
39.
go back to reference Axen I, Bodin L, Bergstrom G, Halasz L, Lange F, Lovgren PW, Rosenbaum A, Leboeuf-Yde C, Jensen I. Clustering patients on the basis of their individual course of low back pain over a six month period. BMC Musculoskelet Disord. 2011;12:99.CrossRefPubMedPubMedCentral Axen I, Bodin L, Bergstrom G, Halasz L, Lange F, Lovgren PW, Rosenbaum A, Leboeuf-Yde C, Jensen I. Clustering patients on the basis of their individual course of low back pain over a six month period. BMC Musculoskelet Disord. 2011;12:99.CrossRefPubMedPubMedCentral
40.
go back to reference Kongsted A, Leboeuf-Yde C. The Nordic back pain subpopulation program--individual patterns of low back pain established by means of text messaging: a longitudinal pilot study. Chiropr Osteopath. 2009;17:11.CrossRef Kongsted A, Leboeuf-Yde C. The Nordic back pain subpopulation program--individual patterns of low back pain established by means of text messaging: a longitudinal pilot study. Chiropr Osteopath. 2009;17:11.CrossRef
41.
go back to reference Macedo LG, Maher CG, Latimer J, McAuley JH, Hodges PW, Rogers WT. Nature and determinants of the course of chronic low back pain over a 12-month period: a cluster analysis. Phys Ther. 2014;94(2):210–21.CrossRefPubMed Macedo LG, Maher CG, Latimer J, McAuley JH, Hodges PW, Rogers WT. Nature and determinants of the course of chronic low back pain over a 12-month period: a cluster analysis. Phys Ther. 2014;94(2):210–21.CrossRefPubMed
42.
go back to reference Dunn KM, Jordan K, Croft PR. Characterizing the course of low back pain: a latent class analysis. Am J Epidemiol. 2006;163(8):754–61.CrossRefPubMed Dunn KM, Jordan K, Croft PR. Characterizing the course of low back pain: a latent class analysis. Am J Epidemiol. 2006;163(8):754–61.CrossRefPubMed
43.
go back to reference Downie AS, Hancock MJ, Rzewuska M, Williams CM, Lin CW, Maher CG. Trajectories of acute low back pain: a latent class growth analysis. Pain. 2016;157(1):225–34.CrossRefPubMed Downie AS, Hancock MJ, Rzewuska M, Williams CM, Lin CW, Maher CG. Trajectories of acute low back pain: a latent class growth analysis. Pain. 2016;157(1):225–34.CrossRefPubMed
44.
go back to reference Deyo RA, Bryan M, Comstock BA, Turner JA, Heagerty P, Friedly J, Avins AL, Nedeljkovic SS, Nerenz DR, Jarvik JG. Trajectories of symptoms and function in older adults with low back disorders. Spine. 2015;40(17):1352–62.CrossRefPubMed Deyo RA, Bryan M, Comstock BA, Turner JA, Heagerty P, Friedly J, Avins AL, Nedeljkovic SS, Nerenz DR, Jarvik JG. Trajectories of symptoms and function in older adults with low back disorders. Spine. 2015;40(17):1352–62.CrossRefPubMed
Metadata
Title
Leg pain location and neurological signs relate to outcomes in primary care patients with low back pain
Authors
Lisbeth Hartvigsen
Lise Hestbaek
Charlotte Lebouef-Yde
Werner Vach
Alice Kongsted
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2017
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-017-1495-3

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