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Published in: BMC Public Health 1/2021

Open Access 01-12-2021 | Chickenpox | Research article

Risk factors for some tropical diseases in an African country

Authors: F.-M. E. Uzoka, C. Akwaowo, C. Nwafor-Okoli, V. Ekpin, C. Nwokoro, M. El Hussein, J. Osuji, F. Aladi, B. Akinnuwesi, T. F. Akpelishi

Published in: BMC Public Health | Issue 1/2021

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Abstract

Background

Often, non-clinical risk factors could affect the predisposition of an individual to diseases. Understanding these factors and their impacts helps in disease prevention and control. This study identified risk factors for malaria, yellow fever, typhoid, chickenpox, measles, hepatitis B, and urinary tract infection in a population in an African country.

Methods

Our study was an observational, correlational, and quantitative one that explored relationships among risk variables and disease prevalence - without modifying or controlling the variables. Data for this study was obtained through random sampling of a population of patients and physicians in the eastern/southern, western, and northern parts of Nigeria in 2015–2016. A total of 2199 patient consultation forms were returned by 102 (out of 125) physicians, and considered useful for analysis. Demographic data of patients, physicians, and diagnosis outcomes were analysed descriptively through frequency distributions, aggregate analysis, and graphs. The influence of risk factors on the disease manifestations (diagnosis outcomes) was determined using regression analysis.

Results

Our results show that living in a tropical climate is by far a major risk factor associated with tropical diseases (malaria: t = 19.9, typhoid: t = − 3.2, chickenpox: t = − 6.5 and typhoid: t = 12.7). The risk for contracting infections is relative to specific diseases; for example, contact with chickenpox infected person poses a high risk of contracting the virus (t = 41.8), while poor personal hygiene predisposes people to high risk of urinary tract infection (t = 23.6). On the other hand, urbanization and homelessness pose very low risks of disposing the individual to the diseases under consideration, while low fluid intake, lack of voiding, and wearing non-cotton underwear predispose individuals to few diseases.

Conclusion

The risk factors identified in our study exert differential and discriminating influences in the causation, predisposition, and transmission of these disease studied. It is recommended that significant effort be devoted by governments in the tropics to the mitigation of these modifiable risk factors. The most important strategy to mitigate the occurrence of these risk factors will be improving the living conditions of people and the provision of social protection measures to reduce the occurrence and burden of these diseases.
Literature
2.
go back to reference Uzoka F-ME, Akinnuwesi BA, Amoo T, Aladi F, Fashoto S, Olaniyan M, et al. A framework for early differential diagnosis of tropical confusable diseases using the fuzzy cognitive map engine. World Academy of Science, Engineering and Technology, International Journal of Computer, Electrical, Automation, Control and Information Engineering. 2016;10(2):346–53. Uzoka F-ME, Akinnuwesi BA, Amoo T, Aladi F, Fashoto S, Olaniyan M, et al. A framework for early differential diagnosis of tropical confusable diseases using the fuzzy cognitive map engine. World Academy of Science, Engineering and Technology, International Journal of Computer, Electrical, Automation, Control and Information Engineering. 2016;10(2):346–53.
4.
go back to reference Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380(9859):2224–60.CrossRef Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380(9859):2224–60.CrossRef
5.
go back to reference Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: global burden of disease study. Lancet. 1997;349(9063):1436–42.CrossRef Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: global burden of disease study. Lancet. 1997;349(9063):1436–42.CrossRef
6.
go back to reference Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet. 2020;396(10258):1204–22.CrossRef Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet. 2020;396(10258):1204–22.CrossRef
7.
8.
go back to reference Abossie A, Yohanes T, Nedu A, Tafesse W, Damitie M. Prevalence of malaria and associated risk factors among febrile children under five years: a cross-sectional study in Arba Minch Zuria District. South Ethiopia Infect Drug Resist. 2020;13:363–72.CrossRef Abossie A, Yohanes T, Nedu A, Tafesse W, Damitie M. Prevalence of malaria and associated risk factors among febrile children under five years: a cross-sectional study in Arba Minch Zuria District. South Ethiopia Infect Drug Resist. 2020;13:363–72.CrossRef
9.
go back to reference Henry J. Tropical And Equatorial Climates. Encyclopedia of World Climatology. 2005:742–50. Henry J. Tropical And Equatorial Climates. Encyclopedia of World Climatology. 2005:742–50.
10.
go back to reference Mogasale VV, Ramani E, Mogasale V, Park JY, Wierzba TF. Estimating typhoid fever risk associated with lack of access to safe water: a systematic literature review. J Environ Public Health. 2018;2018:9589208.CrossRef Mogasale VV, Ramani E, Mogasale V, Park JY, Wierzba TF. Estimating typhoid fever risk associated with lack of access to safe water: a systematic literature review. J Environ Public Health. 2018;2018:9589208.CrossRef
11.
go back to reference Deksissa T, Gebremedhin EZ. A cross-sectional study of enteric fever among febrile patients at ambo hospital: prevalence, risk factors, comparison of Widal test and stool culture and antimicrobials susceptibility pattern of isolates. BMC Infect Dis. 2019;19(1):288.CrossRef Deksissa T, Gebremedhin EZ. A cross-sectional study of enteric fever among febrile patients at ambo hospital: prevalence, risk factors, comparison of Widal test and stool culture and antimicrobials susceptibility pattern of isolates. BMC Infect Dis. 2019;19(1):288.CrossRef
12.
go back to reference Tallon AK, Hill SR, Ignell R. Sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito. Aedes aegypti Scientific Reports. 2019 Jan 10;9(1):43.CrossRef Tallon AK, Hill SR, Ignell R. Sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito. Aedes aegypti Scientific Reports. 2019 Jan 10;9(1):43.CrossRef
13.
go back to reference Socan M, Berginc N, Lajovic J. Varicella susceptibility and transmission dynamics in Slovenia. BMC Public Health. 2010;10:360.CrossRef Socan M, Berginc N, Lajovic J. Varicella susceptibility and transmission dynamics in Slovenia. BMC Public Health. 2010;10:360.CrossRef
14.
go back to reference van Rijckevorsel GGC, Damen M, Sonder GJ, van der Loeff MFS, van den Hoek A. Seroprevalence of varicella-zoster virus and predictors for seronegativity in the Amsterdam adult population. BMC Infect Dis. 2012;12:140.CrossRef van Rijckevorsel GGC, Damen M, Sonder GJ, van der Loeff MFS, van den Hoek A. Seroprevalence of varicella-zoster virus and predictors for seronegativity in the Amsterdam adult population. BMC Infect Dis. 2012;12:140.CrossRef
15.
go back to reference WHO. Varicella. World health organization. 2018; WHO. Varicella. World health organization. 2018;
16.
go back to reference Eke CB, Ogbodo SO, Ukoha OM, Ibekwe RC, Asinobi IN, Ikefuna AN, et al. Seroprevalence and risk factors of hepatitis B virus infection among adolescents in Enugu. Nigeria J Trop Pediatr. 2015;61(6):407–13.PubMed Eke CB, Ogbodo SO, Ukoha OM, Ibekwe RC, Asinobi IN, Ikefuna AN, et al. Seroprevalence and risk factors of hepatitis B virus infection among adolescents in Enugu. Nigeria J Trop Pediatr. 2015;61(6):407–13.PubMed
17.
go back to reference Dovjak M, Kukec A. Identification of health risk factors and their parameters. In: Dovjak M, Kukec a, editors. Creating healthy and Sustainable buildings: an assessment of health risk factors [internet]. Cham: springer international publishing; 2019 [cited 2020 Nov 21]. p. 83–120. Available from: https://doi.org/10.1007/978-3-030-19412-3_3. Dovjak M, Kukec A. Identification of health risk factors and their parameters. In: Dovjak M, Kukec a, editors. Creating healthy and Sustainable buildings: an assessment of health risk factors [internet]. Cham: springer international publishing; 2019 [cited 2020 Nov 21]. p. 83–120. Available from: https://​doi.​org/​10.​1007/​978-3-030-19412-3_​3.​
18.
go back to reference Uzoka F-ME, Ndzinge T. Empirical analysis of biometric technology adoption and acceptance in Botswana. J Syst Softw. 2009 Sep 1;82(9):1550–64.CrossRef Uzoka F-ME, Ndzinge T. Empirical analysis of biometric technology adoption and acceptance in Botswana. J Syst Softw. 2009 Sep 1;82(9):1550–64.CrossRef
19.
go back to reference Federal Ministry of Health. National policy on Integrated Disease Surveillance Response in Nigeria. Abuja: Federal Ministry of Health. 2005;1–7. Federal Ministry of Health. National policy on Integrated Disease Surveillance Response in Nigeria. Abuja: Federal Ministry of Health. 2005;1–7.
20.
go back to reference Isere EE, Fatiregun AA, Ajayi IO. An overview of disease surveillance and notification system in Nigeria and the roles of clinicians in disease outbreak prevention and control. Niger Med J. 2015;56(3):161–8.CrossRef Isere EE, Fatiregun AA, Ajayi IO. An overview of disease surveillance and notification system in Nigeria and the roles of clinicians in disease outbreak prevention and control. Niger Med J. 2015;56(3):161–8.CrossRef
22.
go back to reference Ibrahim LM, Stephen M, Okudo I, Kitgakka SM, Mamadu IN, Njai IF, et al. A rapid assessment of the implementation of integrated disease surveillance and response system in Northeast Nigeria, 2017. BMC Public Health [Internet]. 2020 May 1 [cited 2021 Apr 30];20(1):600. Available from: https://doi.org/10.1186/s12889-020-08707-4. Ibrahim LM, Stephen M, Okudo I, Kitgakka SM, Mamadu IN, Njai IF, et al. A rapid assessment of the implementation of integrated disease surveillance and response system in Northeast Nigeria, 2017. BMC Public Health [Internet]. 2020 May 1 [cited 2021 Apr 30];20(1):600. Available from: https://​doi.​org/​10.​1186/​s12889-020-08707-4.
24.
go back to reference Mordi RM, Burke ME, Odjadjare EE, Enabulele SA, Umeh OJ. Prevalence of urinary tract infections (UTI) among pregnant women in University of Benin teaching hospital (UBTH) Benin City. Nigeria Journal of Asian Scientific Research. 2015;5(4):198–204.CrossRef Mordi RM, Burke ME, Odjadjare EE, Enabulele SA, Umeh OJ. Prevalence of urinary tract infections (UTI) among pregnant women in University of Benin teaching hospital (UBTH) Benin City. Nigeria Journal of Asian Scientific Research. 2015;5(4):198–204.CrossRef
27.
go back to reference Mohammadkhani M, Khanjani N, Bakhtiari B, Sheikhzadeh K. The relation between climatic factors and malaria incidence in Kerman, south east of Iran. Parasite Epidemiology and Control. 2016;1(3):205–10.CrossRef Mohammadkhani M, Khanjani N, Bakhtiari B, Sheikhzadeh K. The relation between climatic factors and malaria incidence in Kerman, south east of Iran. Parasite Epidemiology and Control. 2016;1(3):205–10.CrossRef
28.
go back to reference Thang ND, Erhart A, Speybroeck N, Hung LX, Thuan LK, Hung CT, et al. Malaria in Central Vietnam: analysis of risk factors by multivariate analysis and classification tree models. Malar J. 2008 Jan 30;7(1):28.CrossRef Thang ND, Erhart A, Speybroeck N, Hung LX, Thuan LK, Hung CT, et al. Malaria in Central Vietnam: analysis of risk factors by multivariate analysis and classification tree models. Malar J. 2008 Jan 30;7(1):28.CrossRef
29.
go back to reference Azzarri C, Signorelli S. Climate and poverty in Africa south of the Sahara. World Dev. 2020 Jan 1;125:104691.CrossRef Azzarri C, Signorelli S. Climate and poverty in Africa south of the Sahara. World Dev. 2020 Jan 1;125:104691.CrossRef
32.
go back to reference Hosoglu S, Celen MK, Geyik MF, Akalin S, Ayaz C, Acemoglu H, et al. Risk factors for typhoid fever among adult patients in Diyarbakir. Turkey Epidemiol Infect. 2006 Jun;134(3):612–6.CrossRef Hosoglu S, Celen MK, Geyik MF, Akalin S, Ayaz C, Acemoglu H, et al. Risk factors for typhoid fever among adult patients in Diyarbakir. Turkey Epidemiol Infect. 2006 Jun;134(3):612–6.CrossRef
33.
go back to reference Alba S, Bakker MI, Hatta M, Scheelbeek PFD, Dwiyanti R, Usman R, et al. Risk factors of typhoid infection in the Indonesian archipelago. PLoS One. 2016;11(6):e0155286.CrossRef Alba S, Bakker MI, Hatta M, Scheelbeek PFD, Dwiyanti R, Usman R, et al. Risk factors of typhoid infection in the Indonesian archipelago. PLoS One. 2016;11(6):e0155286.CrossRef
34.
go back to reference Akuu JA, Danyi D, Dapaah C. Factors associated with poor food safety compliance among street food vendors in the Techiman municipality of Ghana. Afr J Food Sci. 2017;11(3):50–7.CrossRef Akuu JA, Danyi D, Dapaah C. Factors associated with poor food safety compliance among street food vendors in the Techiman municipality of Ghana. Afr J Food Sci. 2017;11(3):50–7.CrossRef
35.
go back to reference Okojie PW, Isah EC. Sanitary Conditions of Food Vending Sites and Food Handling Practices of Street Food Vendors in Benin City, Nigeria: Implication for Food Hygiene and Safety [Internet]. Vol. 2014, Journal of Environmental and Public Health. Hindawi; 2014 [cited 2020 Nov 19]. p. e701316. Available from: https://www.hindawi.com/journals/jeph/2014/701316/ Okojie PW, Isah EC. Sanitary Conditions of Food Vending Sites and Food Handling Practices of Street Food Vendors in Benin City, Nigeria: Implication for Food Hygiene and Safety [Internet]. Vol. 2014, Journal of Environmental and Public Health. Hindawi; 2014 [cited 2020 Nov 19]. p. e701316. Available from: https://​www.​hindawi.​com/​journals/​jeph/​2014/​701316/​
36.
go back to reference Midekisa A, Beyene B, Mihretie A, Bayabil E, Wimberly M. Seasonal associations of climatic drivers and malaria in the highlands of Ethiopia. Parasit Vectors. 2015;8:339–9.CrossRef Midekisa A, Beyene B, Mihretie A, Bayabil E, Wimberly M. Seasonal associations of climatic drivers and malaria in the highlands of Ethiopia. Parasit Vectors. 2015;8:339–9.CrossRef
37.
go back to reference Momoh J, Opaluwah A, Albeera H. Challenges Facing Nigeria’s Urban Environment: The Abuja Case. :16. Momoh J, Opaluwah A, Albeera H. Challenges Facing Nigeria’s Urban Environment: The Abuja Case. :16.
38.
go back to reference Muhammed, Sabiu S, Khalil M. AN OVERVIEW OF URBANIZATION AND ITS CHALLENGES ON SUSTAINABLE DEVELOPMENT IN NIGERIA. Dutse Journal of Pure and Applied Sciences 1(1) June 2015. 2015 Sep 10;1:19–29. Muhammed, Sabiu S, Khalil M. AN OVERVIEW OF URBANIZATION AND ITS CHALLENGES ON SUSTAINABLE DEVELOPMENT IN NIGERIA. Dutse Journal of Pure and Applied Sciences 1(1) June 2015. 2015 Sep 10;1:19–29.
39.
go back to reference Pinsent A, Read JM, Griffin JT, Smith V, Gething PW, Ghani AC, et al. Risk factors for UK plasmodium falciparum cases. Malar J. 2014;13(1):298.CrossRef Pinsent A, Read JM, Griffin JT, Smith V, Gething PW, Ghani AC, et al. Risk factors for UK plasmodium falciparum cases. Malar J. 2014;13(1):298.CrossRef
41.
go back to reference Raoult D, Foucault C, Brouqui P. Infections in the homeless. Lancet Infect Dis. 2001;1(2):77–84.CrossRef Raoult D, Foucault C, Brouqui P. Infections in the homeless. Lancet Infect Dis. 2001;1(2):77–84.CrossRef
42.
go back to reference Badiaga S, Raoult D, Brouqui P. Preventing and controlling emerging and reemerging transmissible diseases in the homeless. Emerg Infect Dis. 2008;14(9):1353–9.CrossRef Badiaga S, Raoult D, Brouqui P. Preventing and controlling emerging and reemerging transmissible diseases in the homeless. Emerg Infect Dis. 2008;14(9):1353–9.CrossRef
43.
go back to reference Salez N, Benkouiten S, Sekene B, Charrel R, Brouqui P. Respiratory viruses within homeless shelters in Marseille. France BMC Research Notes. 2014;7:81.CrossRef Salez N, Benkouiten S, Sekene B, Charrel R, Brouqui P. Respiratory viruses within homeless shelters in Marseille. France BMC Research Notes. 2014;7:81.CrossRef
44.
go back to reference Mackey MA, Ali MRK, Austin LA, Near RD, El-Sayed MA. The Most effective gold Nanorod size for Plasmonic Photothermal therapy: theory and in vitro experiments. J Phys Chem B. 2014;118(5):1319–26.CrossRef Mackey MA, Ali MRK, Austin LA, Near RD, El-Sayed MA. The Most effective gold Nanorod size for Plasmonic Photothermal therapy: theory and in vitro experiments. J Phys Chem B. 2014;118(5):1319–26.CrossRef
45.
go back to reference Ooi GL, Phua KH. Urbanization and slum formation. J Urban Health. 2007;84(S1):27–34.CrossRef Ooi GL, Phua KH. Urbanization and slum formation. J Urban Health. 2007;84(S1):27–34.CrossRef
46.
go back to reference Eastwood R, Lipton M. Pro-poor Growth and Pro-growth Poverty Reduction: Meaning, Evidence, and Policy Implications. :37. Eastwood R, Lipton M. Pro-poor Growth and Pro-growth Poverty Reduction: Meaning, Evidence, and Policy Implications. :37.
47.
go back to reference Alawode GO, Adewole DA. Assessment of the design and implementation challenges of the National Health Insurance Scheme in Nigeria: a qualitative study among sub-national level actors, healthcare and insurance providers. BMC Public Health. 2021;21(1):124.CrossRef Alawode GO, Adewole DA. Assessment of the design and implementation challenges of the National Health Insurance Scheme in Nigeria: a qualitative study among sub-national level actors, healthcare and insurance providers. BMC Public Health. 2021;21(1):124.CrossRef
Metadata
Title
Risk factors for some tropical diseases in an African country
Authors
F.-M. E. Uzoka
C. Akwaowo
C. Nwafor-Okoli
V. Ekpin
C. Nwokoro
M. El Hussein
J. Osuji
F. Aladi
B. Akinnuwesi
T. F. Akpelishi
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2021
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-021-12286-3

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