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Published in: BMC Public Health 1/2019

Open Access 01-12-2019 | Human Immunodeficiency Virus | Research article

Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa

Authors: Niklaus Daniel Labhardt, Isaac Ringera, Thabo Ishmael Lejone, Alain Amstutz, Thomas Klimkait, Josephine Muhairwe, Tracy Renee Glass

Published in: BMC Public Health | Issue 1/2019

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Abstract

Background

Home-based HIV testing and counselling (HB-HTC) is frequently used to increase awareness of HIV status in sub-Saharan Africa. Whereas acceptance of HB-HTC is usually high, testing coverage may remain low due to household members being absent during the home visits. This study assessed whether two consecutive visits, one during the week, one on the weekend, increase coverage.

Methods

The study was a predefined nested-study of the CASCADE-trial protocol and conducted in 62 randomly selected villages and 17 urban areas in Butha-Buthe district, Lesotho. HB-HTC teams visited each village/urban area twice: first during a weekday, followed by a weekend visit to catch-up for household members absent during the week. Primary outcome was HTC coverage after first and second visit. Coverage was defined as all individuals who knew their HIV status out of all household members (present and absent).

Results

HB-HTC teams visited 6665 households with 18,286 household members. At first visit, 69.2 and 75.4% of household members were encountered in rural and urban households respectively (p < 0.001) and acceptance for testing was 88.5% in rural and 79.5% in urban areas (p < 0.001), resulting in a coverage of 61.8 and 61.5%, respectively. After catch-up visit, the HTC coverage increased to 71.9% in rural and 69.4% in urban areas. The number of first time testers was higher at the second visit (47% versus 35%, p < 0.001). Direct cost per person tested and per person tested HIV positive were lower during weekdays (10.50 and 335 USD) than during weekends (20 and 1056 USD).

Conclusions

A catch-up visit on weekends increased the proportion of persons knowing their HIV status from 62 to 71% and reached more first-time testers. However, cost per person tested during catch-up visits was nearly twice the cost during first visit.

Trial registration

NCT02692027 (prospectively registered on February 21, 2016).
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Literature
2.
go back to reference Iwuji C, Newell M-L. Public health action. HIV test “front door” to UNAIDS 90-90-90 target 7:79; 2017. Iwuji C, Newell M-L. Public health action. HIV test “front door” to UNAIDS 90-90-90 target 7:79; 2017.
5.
go back to reference WHO (2015) Consolidated guidelines on HIV testing services. World Heal. Organ. WHO (2015) Consolidated guidelines on HIV testing services. World Heal. Organ.
6.
go back to reference Sharma M, Ying R, Tarr G, Barnabas R. Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa. Nature. 2015;528:S77–85.CrossRef Sharma M, Ying R, Tarr G, Barnabas R. Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa. Nature. 2015;528:S77–85.CrossRef
7.
go back to reference Molesworth AM, Ndhlovu R, Banda E, Saul J, Ngwira B, Glynn JR, Crampin AC, French N. High accuracy of home-based community rapid HIV testing in rural Malawi. J Acquir Immune Defic Syndr. 2010;55:625–30.CrossRef Molesworth AM, Ndhlovu R, Banda E, Saul J, Ngwira B, Glynn JR, Crampin AC, French N. High accuracy of home-based community rapid HIV testing in rural Malawi. J Acquir Immune Defic Syndr. 2010;55:625–30.CrossRef
8.
go back to reference Wachira J, Ndege S, Koech J, Vreeman RC, Ayuo P, Braitstein P. HIV testing uptake and prevalence among adolescents and adults in a large home-based HIV testing program in Western Kenya. J Acquir Immune Defic Syndr. 2014;65:e58–66.CrossRef Wachira J, Ndege S, Koech J, Vreeman RC, Ayuo P, Braitstein P. HIV testing uptake and prevalence among adolescents and adults in a large home-based HIV testing program in Western Kenya. J Acquir Immune Defic Syndr. 2014;65:e58–66.CrossRef
9.
go back to reference Petersen M, Balzer L, Kwarsiima D, et al. Association of implementation of a universal testing and treatment intervention with HIV diagnosis, receipt of antiretroviral therapy, and viral suppression in East Africa. JAMA. 2017;317:2196–206.CrossRef Petersen M, Balzer L, Kwarsiima D, et al. Association of implementation of a universal testing and treatment intervention with HIV diagnosis, receipt of antiretroviral therapy, and viral suppression in East Africa. JAMA. 2017;317:2196–206.CrossRef
13.
go back to reference Labhardt ND, Ringera I, Lejone TI, Klimkait T, Muhairwe J, Amstutz A, Glass TR. Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho: the CASCADE randomized clinical trial. JAMA - J Am Med Assoc. 2018. https://doi.org/10.1001/jama.2018.1818. Labhardt ND, Ringera I, Lejone TI, Klimkait T, Muhairwe J, Amstutz A, Glass TR. Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho: the CASCADE randomized clinical trial. JAMA - J Am Med Assoc. 2018. https://​doi.​org/​10.​1001/​jama.​2018.​1818.
14.
go back to reference Labhardt ND, Ringera I, Lejone TI, et al. Same day ART initiation versus clinic-based pre-ART assessment and counselling for individuals newly tested HIV-positive during community-based HIV testing in rural Lesotho - a randomized controlled trial (CASCADE trial). BMC Public Health. 2016. https://doi.org/10.1186/s12889-016-2972-6. Labhardt ND, Ringera I, Lejone TI, et al. Same day ART initiation versus clinic-based pre-ART assessment and counselling for individuals newly tested HIV-positive during community-based HIV testing in rural Lesotho - a randomized controlled trial (CASCADE trial). BMC Public Health. 2016. https://​doi.​org/​10.​1186/​s12889-016-2972-6.
15.
go back to reference Ministry of Health L. Lesotho population-based HIV impact assessment (LePHIA) summary sheet: preliminary findings; 2017. p. 1–6. Ministry of Health L. Lesotho population-based HIV impact assessment (LePHIA) summary sheet: preliminary findings; 2017. p. 1–6.
16.
go back to reference Bemelmans M, Baert S, Negussie E, Bygrave H, Biot M, Jamet C, Ellman T, Banda A, van den Akker T, Ford N. Sustaining the future of HIV counselling to reach 90-90-90: a regional country analysis. J Int AIDS Soc. 2016;19:20751.CrossRef Bemelmans M, Baert S, Negussie E, Bygrave H, Biot M, Jamet C, Ellman T, Banda A, van den Akker T, Ford N. Sustaining the future of HIV counselling to reach 90-90-90: a regional country analysis. J Int AIDS Soc. 2016;19:20751.CrossRef
17.
go back to reference Government of Lesotho. National guidelines on the use of antiretroviral therapy for HIV prevention and treatment. 5th ed; 2016. Government of Lesotho. National guidelines on the use of antiretroviral therapy for HIV prevention and treatment. 5th ed; 2016.
18.
go back to reference Chamie G, Clark TD, Kabami J, et al. A hybrid mobile approach for population-wide HIV testing in rural East Africa: an observational study. Lancet HIV. 2016;3:e111–9.CrossRef Chamie G, Clark TD, Kabami J, et al. A hybrid mobile approach for population-wide HIV testing in rural East Africa: an observational study. Lancet HIV. 2016;3:e111–9.CrossRef
19.
go back to reference Kadede K, Ruel T, Kabami J, et al. Increased adolescent HIV testing with a hybrid mobile strategy in Uganda and Kenya. AIDS. 2016;30:2121–6.CrossRef Kadede K, Ruel T, Kabami J, et al. Increased adolescent HIV testing with a hybrid mobile strategy in Uganda and Kenya. AIDS. 2016;30:2121–6.CrossRef
20.
go back to reference Asiimwe S, Ross JM, Arinaitwe A, Tumusiime O, Turyamureeba B, Roberts DA, O’Malley G, Barnabas RV. Expanding HIV testing and linkage to care in southwestern Uganda with community health extension workers. J Int AIDS Soc. 2017;20:80–7.CrossRef Asiimwe S, Ross JM, Arinaitwe A, Tumusiime O, Turyamureeba B, Roberts DA, O’Malley G, Barnabas RV. Expanding HIV testing and linkage to care in southwestern Uganda with community health extension workers. J Int AIDS Soc. 2017;20:80–7.CrossRef
21.
go back to reference Chang W, Chamie G, Mwai D, et al. Implementation and operational research: cost and efficiency of a hybrid Mobile multidisease testing approach with high HIV testing coverage in East Africa. J Acquir Immune Defic Syndr. 2016;73:e39–45.CrossRef Chang W, Chamie G, Mwai D, et al. Implementation and operational research: cost and efficiency of a hybrid Mobile multidisease testing approach with high HIV testing coverage in East Africa. J Acquir Immune Defic Syndr. 2016;73:e39–45.CrossRef
22.
go back to reference Pegurri E, Fox-Rushby JA, Damian W. The effects and costs of expanding the coverage of immunisation services in developing countries: a systematic literature review. Vaccine. 2005;23:1624–35.CrossRef Pegurri E, Fox-Rushby JA, Damian W. The effects and costs of expanding the coverage of immunisation services in developing countries: a systematic literature review. Vaccine. 2005;23:1624–35.CrossRef
23.
go back to reference Lugada E, Millar D, Haskew J, et al. Rapid implementation of an integrated large-scale HIV counseling and testing, malaria, and diarrhea prevention campaign in rural Kenya. PLoS One. 2010;5:e12435.CrossRef Lugada E, Millar D, Haskew J, et al. Rapid implementation of an integrated large-scale HIV counseling and testing, malaria, and diarrhea prevention campaign in rural Kenya. PLoS One. 2010;5:e12435.CrossRef
24.
go back to reference Chamie G, Kwarisiima D, Clark TD, et al. Leveraging rapid community-based HIV testing campaigns for non-communicable diseases in rural Uganda. PLoS One. 2012;7:e43400.CrossRef Chamie G, Kwarisiima D, Clark TD, et al. Leveraging rapid community-based HIV testing campaigns for non-communicable diseases in rural Uganda. PLoS One. 2012;7:e43400.CrossRef
25.
go back to reference Chamie G, Kwarisiima D, Clark TD, et al. Uptake of community-based HIV testing during a multi-disease health campaign in rural Uganda. PLoS One. 2014;9:e84317.CrossRef Chamie G, Kwarisiima D, Clark TD, et al. Uptake of community-based HIV testing during a multi-disease health campaign in rural Uganda. PLoS One. 2014;9:e84317.CrossRef
26.
go back to reference Lewis L, Maughan-Brown B, Grobler A, Cawood C, Khanyile D, Glenshaw M, Kharsany ABM. Impact of home-based HIV testing services on Progress toward the UNAIDS 90-90-90 targets in a Hyperendemic area of South Africa. JAIDS J Acquir Immune Defic Syndr. 2019;80:135–44.CrossRef Lewis L, Maughan-Brown B, Grobler A, Cawood C, Khanyile D, Glenshaw M, Kharsany ABM. Impact of home-based HIV testing services on Progress toward the UNAIDS 90-90-90 targets in a Hyperendemic area of South Africa. JAIDS J Acquir Immune Defic Syndr. 2019;80:135–44.CrossRef
27.
go back to reference Camlin CS, Ssemmondo E, Chamie G, et al. Men “missing” from population-based HIV testing: insights from qualitative research. AIDS Care. 2016;28(Suppl 3):67–73.CrossRef Camlin CS, Ssemmondo E, Chamie G, et al. Men “missing” from population-based HIV testing: insights from qualitative research. AIDS Care. 2016;28(Suppl 3):67–73.CrossRef
28.
go back to reference Yamanis TJ, Dervisevic E, Mulawa M, Conserve DF, Barrington C, Kajula LJ, Maman S. Social network influence on HIV testing among urban men in Tanzania. AIDS Behav. 2017;21:1171–82.CrossRef Yamanis TJ, Dervisevic E, Mulawa M, Conserve DF, Barrington C, Kajula LJ, Maman S. Social network influence on HIV testing among urban men in Tanzania. AIDS Behav. 2017;21:1171–82.CrossRef
30.
go back to reference Amstutz A, Lejone TI, Khesa L (2019) The HOSENG trial – effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho. Trials in press: Amstutz A, Lejone TI, Khesa L (2019) The HOSENG trial – effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho. Trials in press:
31.
go back to reference Madiba S, Mokgatle M. Parents support implementation of HIV testing and counseling at school: cross-sectional study with parents of adolescent attending high School in Gauteng and North West Provinces, South Africa. AIDS Res Treat. 2016;2016:4842814.PubMedPubMedCentral Madiba S, Mokgatle M. Parents support implementation of HIV testing and counseling at school: cross-sectional study with parents of adolescent attending high School in Gauteng and North West Provinces, South Africa. AIDS Res Treat. 2016;2016:4842814.PubMedPubMedCentral
32.
go back to reference De Cock KM, Barker JL, Baggaley R, El Sadr WM. Where are the positives? HIV testing in sub-Saharan Africa in the era of test and treat. AIDS. 2019;33:349–52.CrossRef De Cock KM, Barker JL, Baggaley R, El Sadr WM. Where are the positives? HIV testing in sub-Saharan Africa in the era of test and treat. AIDS. 2019;33:349–52.CrossRef
33.
go back to reference Sulat JS, Prabandari YS, Sanusi R, Hapsari ED, Santoso B. The impacts of community-based HIV testing and counselling on testing uptake. J Heal Res. 2018;32:152–63.CrossRef Sulat JS, Prabandari YS, Sanusi R, Hapsari ED, Santoso B. The impacts of community-based HIV testing and counselling on testing uptake. J Heal Res. 2018;32:152–63.CrossRef
Metadata
Title
Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa
Authors
Niklaus Daniel Labhardt
Isaac Ringera
Thabo Ishmael Lejone
Alain Amstutz
Thomas Klimkait
Josephine Muhairwe
Tracy Renee Glass
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2019
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-019-7784-z

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