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BMC Public Health
Published in: BMC Public Health 1/2016

Open Access 01-12-2015 | Research article

Epidemiology of diabetes and complications among adults in the Republic of Ireland 1998-2015: a systematic review and meta-analysis

Published in: BMC Public Health | Issue 1/2016

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Abstract

Background

Accurate estimates of the burden of diabetes are essential for future planning and evaluation of services. In Ireland, there is no diabetes register and prevalence estimates vary. The aim of this review was to systematically identify and review studies reporting the prevalence of diabetes and complications among adults in Ireland between 1998 and 2015 and to examine trends in prevalence over time.

Methods

A systematic literature search was carried out using PubMed and Embase. Diabetes prevalence estimates were pooled by random-effects meta-analysis. Poisson regression was carried out using data from four nationally representative studies to calculate prevalence rates of doctor diagnosed diabetes between 1998 and 2015 and was also used to assess whether the rate of doctor diagnosed diabetes changed over time.

Results

Fifteen studies (eight diabetes prevalence and seven complication prevalence) were eligible for inclusion. In adults aged 18 years and over, the national prevalence of doctor diagnosed diabetes significantly increased from 2.2 % in 1998 to 5.2 % in 2015 (p trend ≤ 0.001). The prevalence of diabetes complications ranged widely depending on study population and methodology used (6.5–25.2 % retinopathy; 3.2–32.0 % neuropathy; 2.5-5.2 % nephropathy).

Conclusions

Between 1998 and 2015, there was a significant increase in the prevalence of doctor diagnosed diabetes among adults in Ireland. Trends in microvascular and macrovascular complications prevalence could not be examined due to heterogeneity between studies and the limited availability of data. Reliable baseline data are needed to monitor improvements in care over time at a national level. A comprehensive national diabetes register is urgently needed in Ireland.
Appendix
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Literature
1.
Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414:782–7.CrossRefPubMed
2.
International Diabetes Federation. IDF Diabetes Atlas, 6th edn. International Diabetes Federation. Brussels, Belgium: 2013.
3.
Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2 · 7 million participants. Lancet. 2011;378:31–40.CrossRefPubMed
4.
Kearns K, Dee A, Fitzgerald A, Doherty E, Perry IJ. Chronic disease burden associated with overweight and obesity in Ireland: the effects of a small BMI reduction at population level. BMC Public Health. 2014;14:143.CrossRefPubMedPubMedCentral
5.
International Diabetes Federation. Diabetes Atlas, 2000, 1st edn. International Diabetes Federation. Brussels, Belgium: 2000.
6.
Venkat Narayan KM, Greg EW, Fagot-Campagna A, Engelgau MM, Vinicor F. Diabetes- a common, growing, serious, costly and potentially preventable public health problem. Diabetes Res Clin Pract. 2000;50:S77-S84. 
7.
Garcia MJ, McNamara PM, Gordon T, Kannell WB. Morbidity and mortality in diabetics in the framingham population: Sixteen year follow-up study. Diabetes. 1974;23:105–11.CrossRefPubMed
8.
Roper NA, Bilous RW, Kelly WF, Unwin NC, Connolly VM. Cause-specific mortality in a population with diabetes: South Tees Diabetes Mortality Study. Diabetes Care. 2002;25:43–8.CrossRefPubMed
9.
Tamayo T, Rosenbauer J, Wild SH, Spijkerman AM, Baan C, Forouhi NG, et al. Diabetes in Europe: an update. Diabetes Res Clin Pract. 2014;103:206–17.CrossRefPubMed
10.
Heidemann C, Du Y, Paprott R, Haftenberger M, Rathmann W, Scheidt-Nave C. Temporal changes in the prevalence of diagnosed diabetes, undiagnosed diabetes and prediabetes: findings from the German health interview and examination surveys in 1997–1999 and 2008–2011. Diabetic Med. 2015. doi:10.​1111/​dme.​13008.PubMed
11.
Balanda KP, Buckley CM, Barron SJ, Fahy LE, Madden JM, Harrington JM, et al. Prevalence of diabetes in the Republic of Ireland: Results from the National Health Survey (SLAN) 2007. PLoS One. 2013;8:e78406.CrossRefPubMedPubMedCentral
12.
13.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151:264–9.CrossRefPubMed
14.
Munn Z, Moola S, Riitano D, Lisy K. The development of a critical appraisal tool for use in systematic reviews addressing questions of prevalence. Int J Health Policy Manag. 2014;3:123–8.CrossRefPubMedPubMedCentral
15.
16.
Department of Health and Children. Survey on Lifestyle and Attitude to Nutrition (SLÁN). Galway: NUIG, Centre for Health Promotion Studies; 1998.
17.
Department of Health and Children. Survey on Lifestyle and Attitude to Nutrition (SLÁN). Galway: NUIG, Centre for Health promotion Studies; 2002.
18.
19.
Kearney PM, Cronin H, O’Regan C, Kamiya Y, Savva GM, Whelan B, et al. Cohort profile: The Irish longitudinal study on ageing. Int J Epidemiol. 2011;40:877–84.CrossRefPubMed
20.
Kenny R, Whelan B, Cronin H, Kamiya Y, Kearney P, O’Regan C, et al. The design of the Irish longitudinal study on ageing. Dublin: Trinity College Dublin; 2010.
21.
22.
Shiely F, Kelleher C. Older people in Ireland: A profile of health status, lifestyle and socio-economic factors from SLÁN: National Council on Ageing and Older People Dublin; 2004.
23.
Creagh D, Neilson S, Collins A, Colwell N, Hinchion R, Drew C, et al. Established cardiovascular disease and CVD risk factors in a primary care population of middle-aged Irish men and women. Ir Med J. 2002;95:298–301.PubMed
24.
Gallagher N, Bennett K, Smith SM, O’Reilly D. Impact of two different health systems on the burden of type 2 diabetes. J Health Serv Res Policy. 2014;19:69–76.CrossRefPubMed
25.
Leahy S, O’Halloran A, O’Leary N, Healy M, McCormack M, Kenny R, et al. Prevalence and correlates of diagnosed and undiagnosed type 2 diabetes mellitus and pre-diabetes in older adults: Findings from the Irish Longitudinal Study on Ageing (TILDA). Diabetes Res Clin Prac. 2015;110(3):241–9.CrossRef
26.
OConnor JM, Millar SR, Buckley CM, Kearney PM, Perry IJ. The prevalence and determinants of undiagnosed and diagnosed type 2 diabetes in middle-aged irish adults. PLoS One. 2013;8(11):e80504.CrossRef
27.
28.
Kelliher C, Kenny D, O’Brien C. Trends in blind registration in the adult population of the Republic of Ireland 1996-2003. Br J Ophthalmol. 2006;90:367–71.CrossRefPubMedPubMedCentral
29.
Buckley CM, O’Farrell A, Canavan RJ, Lynch AD, De La Harpe DV, Bradley CP, et al. Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland. PLoS One. 2012;7:e41492.
30.
Hurley L, Kelly L, Garrow AP, Glynn LG, McIntosh C, Alvarez-Iglesias A, et al. A prospective study of risk factors for foot ulceration: The West of Ireland Diabetes Foot Study. QJM. 2013;106:1103–10.CrossRefPubMed
31.
Farrell C, Moran J. Comparison of comorbidities in patients with pre-diabetes to those with diabetes mellitus type 2. Ir Med J. 2014;107:72–4.PubMed
32.
Tracey ML, McHugh SM, Buckley CM, Canavan RJ, Fitzgerald AP, Kearney PM. The prevalence of Type 2 diabetes and related complications in a nationally representative sample of adults aged 50 and over in the Republic of Ireland. Diabet Med. 2015. doi:10.​1111/​dme.​12845.PubMed
33.
McHugh SM, Buckley CM, Murphy K, Doherty S, O’Keeffe G, Alade J, et al. Quality-assured screening for diabetic retinopathy delivered in primary care in Ireland: an observational study. Br J Gen Pract. 2013;63:e134–40.CrossRefPubMed
34.
Marsden P, Brennan C, McHugh SM, Harkins V. Audit Report of the HSE Midland Diabetes StructuredCare Programme. Department of Public Health. Health Service Executive Dublin Mid-Leinster. 2010.
35.
Pereira M, Carreira H, Lunet N, Azevedo A. Trends in prevalence of diabetes mellitus and mean fasting glucose in Portugal (1987-2009): a systematic review. Public Health. 2014;128:214–21.CrossRefPubMed
36.
37.
Hall V, Thomsen RW, Henriksen O, Lohse N. Diabetes in Sub Saharan Africa 1999-2011: epidemiology and public health implications. A systematic review. BMC Public Health. 2011;11:564.CrossRefPubMedPubMedCentral
38.
Hamer M, Kengne AP, Batty GD, Cooke D, Stamatakis E. Temporal trends in diabetes prevalence and key diabetes risk factors in Scotland, 2003-2008. Diabet Med. 2011;28:595–8.CrossRefPubMed
39.
Lipscombe LL, Hux JE. Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: a population-based study. Lancet. 2007;369:750–6.CrossRefPubMed
40.
Bonaldi C, Vernay M, Roudier C, Salanave B, Oleko A, Malon A, et al. A first national prevalence estimate of diagnosed and undiagnosed diabetes in France in 18- to 74-year-old individuals: the French Nutrition and Health Survey 2006/2007. Diabet Med. 2011;28:583–9.CrossRefPubMed
41.
Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375:2215–22.CrossRefPubMed
42.
Sattar N. Gender aspects in type 2 diabetes mellitus and cardiometabolic risk. Best Pract Res Clin Endocrinol Metab. 2013;27:501–7.CrossRefPubMed
43.
Cowie CC, Rust KF, Byrd-Holt DD, Gregg EW, Ford ES, Geiss LS, et al. Prevalence of diabetes and high risk for diabetes using A1C criteria in the U.S. population in 1988-2006. Diabetes Care. 2010;33:562–8.CrossRefPubMedPubMedCentral
44.
Clarke A. Diabetes care: Securing the future. Action plan for implementation of the St. Vincent declaration. Dublin: Diabetes Service Development Group; 2002.
45.
Sinnott M, Kinsley BT, Jackson AD, Walsh C, O’Grady T, Nolan JJ, et al. Fasting plasma glucose as initial screening for diabetes and prediabetes in Irish adults: The Diabetes Mellitus and Vascular Health Initiative (DMVhi). PLoS One. 2015;10:e0122704.CrossRefPubMedPubMedCentral
46.
Juarez DT, Demaris KM, Goo R, Mnatzaganian CL, Wong Smith H. Significance of HbA(1c) and its measurement in the diagnosis of diabetes mellitus: US experience. Diabetes Metab Syndr Obes. 2014;7:487-494.
47.
Nolan JJ, O’Halloran D, McKenna TJ, Firth R, Redmond S. The cost of treating type 2 diabetes (CODEIRE). Ir Med J. 2006;99:307–10.PubMed
48.
Ruta LM, Magliano DJ, Lemesurier R, Taylor HR, Zimmet PZ, Shaw JE. Prevalence of diabetic retinopathy in Type 2 diabetes in developing and developed countries. Diabet Med. 2013;30:387–98.CrossRefPubMed
49.
Yau JW, Rogers SL, Kawasaki R, Lamoureux EL, Kowalski JW, Bek T, et al. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012;35:556–64.CrossRefPubMedPubMedCentral
50.
51.
Savva GM. In fifty plus in Ireland 2011: First results from the Irish longitudinal study on ageing. Dublin: Trinity College Dublin; 2011.
52.
Critchfield T, Tucker J, Vuchinich R. Self-report methods. In: Lattal K, Perone M, editors. Handbook of research methods in human operant behavior. US: Springer; 1998. p. 435–70.CrossRef
53.
MacLennan PA, McGwin Jr G, Searcey K, Owsley C. Medical record validation of self-reported eye diseases and eye care utilization among older adults. Curr Eye Res. 2013;38:1–8.CrossRefPubMed
54.
Comino EJ, Tran DT, Haas M, Flack J, Jalaludin B, Jorm L, et al. Validating self-report of diabetes use by participants in the 45 and Up Study: a record linkage study. BMC Health Serv Res. 2013;13:481.CrossRefPubMedPubMedCentral
55.
Okura Y, Urban LH, Mahoney DW, Jacobsen SJ, Rodeheffer RJ. Agreement between self-report questionnaires and medical record data was substantial for diabetes, hypertension, myocardial infarction and stroke but not for heart failure. J Clin Epidemiol. 2004;57:1096–103.CrossRefPubMed
56.
Galenkamp H, Huisman M, Braam AW, Schellevis FG, Deeg DJ. Disease prevalence based on older people’s self-reports increased, but patient-general practitioner agreement remained stable, 1992-2009. J Clin Epidemiol. 2014;67:773–80.CrossRefPubMed
57.
Maruthur NM. The growing prevalence of type 2 diabetes: increased incidence or improved survival? Curr Diab Rep. 2013;13:786–94.CrossRefPubMed
58.
59.
Metadata
Title
Epidemiology of diabetes and complications among adults in the Republic of Ireland 1998-2015: a systematic review and meta-analysis
Publication date
01-12-2015
Published in
BMC Public Health / Issue 1/2016
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-016-2818-2

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