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Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Socioeconomic inequalities in non-communicable diseases and their risk factors: an overview of systematic reviews

Authors: Isolde Sommer, Ursula Griebler, Peter Mahlknecht, Kylie Thaler, Kathryn Bouskill, Gerald Gartlehner, Shanti Mendis

Published in: BMC Public Health | Issue 1/2015

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Abstract

Background

Non-communicable diseases (NCDs) are the largest cause of premature death worldwide. Socioeconomic inequalities contribute to a disparity in the burden of NCDs among disadvantaged and advantaged populations in low (LIC), middle (MIC), and high income countries (HIC). We conducted an overview of systematic reviews to systematically and objectively assess the available evidence on socioeconomic inequalities in relation to morbidity and mortality of NCDs and their risk factors.

Methods

We searched PubMed, The Cochrane Library, EMBASE, SCOPUS, Global Health, and Business Source Complete for relevant systematic reviews published between 2003 and December 2013. Two authors independently screened abstracts and full-text publications and determined the risk of bias of the included systematic reviews.

Results

We screened 3302 abstracts, 173 full-text publications and ultimately included 22 systematic reviews. Most reviews had major methodological shortcomings; however, our synthesis showed that having low socioeconomic status (SES) and/or living in low and middle income countries (LMIC) increased the risk of developing cardiovascular diseases (CVD), lung and gastric cancer, type 2 diabetes, and chronic obstructive pulmonary disease (COPD). Furthermore, low SES increased the risk of mortality from lung cancer, COPD, and reduced breast cancer survival in HIC. Reviews included here indicated that lower SES is a risk factor for obesity in HIC, but this association varied by SES measure. Early case fatalities of stroke were lower and survival of retinoblastoma was higher in MIC compared to LIC.

Conclusions

The current evidence supports an association between socioeconomic inequalities and NCDs and risk factors for NCDs. However, this evidence is incomplete and limited by the fairly low methodological quality of the systematic reviews, including shortcomings in the study selection and quality assessment process.
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Metadata
Title
Socioeconomic inequalities in non-communicable diseases and their risk factors: an overview of systematic reviews
Authors
Isolde Sommer
Ursula Griebler
Peter Mahlknecht
Kylie Thaler
Kathryn Bouskill
Gerald Gartlehner
Shanti Mendis
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-2227-y

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