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Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Effects of bed nets and anti-malaria drugs use on childhood mortality in Kenya’s malaria endemic and epidemic areas

Author: Boniface O K’Oyugi

Published in: BMC Public Health | Issue 1/2015

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Abstract

Background

The Kenya Demographic and Health Surveys (KDHS) data collected since 1989 indicate that malaria prone areas have consistently recorded the highest childhood mortality rates. Malaria control programme information also indicates that malaria contributes to about 20 per cent of the deaths among under-five year old children. The 2009–2017 National Malaria Strategy is being implemented to reduce malaria morbidity and mortality. Its key interventions include: bed nets use; anti-malaria drugs use during pregnancy for prevention; and, prompt treatment using anti-malaria drugs of children with fever. This study seeks to establish differentials in childhood mortality rates by these interventions in three malaria prone areas defined as highland epidemic, coast endemic and lake endemic. It also seeks to determine the effects of these interventions on childhood mortality.

Methods

The data used is drawn from the 2008/9 KDHS. The study sample consists of 3,728 children born less than 60 months prior to the survey. The direct demographic method for estimation of childhood mortality rates and multivariate Poisson regression models are used to analyse the data.

Results

The findings show that use of bed nets and anti-malaria drugs are not high in Kenya’s malaria prone areas. On the average, only about 60% of the children are found to be in higher use category for each of the three intervention measures. The childhood mortality rates show that higher use of prompt treatment with anti-malaria drugs for children with fever has lower infant and under-five mortality rates in all malaria epidemic and endemic areas compared to lower use. Higher bed nets use has lower childhood mortality rates compared to lower use in coast and lake endemic areas. Higher use of anti-malaria drugs during pregnancy for prevention has lower childhood mortality rates in highland epidemic and lake endemic areas compared to lower use. The regression models fitted show that in highland epidemic area, higher use of anti-malaria drugs during pregnancy for prevention has significant reduction effect on childhood mortality compared to lower use in the presence of breastfeeding duration, toilet facility type and age of child variables. The regression models also show that in combined malaria prone areas, higher prompt treatment of children with fever using anti-malaria drugs has significant reduction effect on both infant and child mortality compared to lower prompt treatment in the presence of breastfeeding duration and toilet facility type variables.

Conclusion

This study underscore the need for increasing uptake of malaria interventions and complementing them with longer breastfeeding duration and improved toilet facility in efforts towards reducing infant and child mortality rates in Kenya’s malaria prone areas. There is also need to improve quality of individual household data for malaria module in future KDHS undertakings.
Literature
1.
go back to reference Division of Malaria Control. Malaria Fact Sheet. Nairobi: Ministry of Public Health and Sanitation; 2011. Division of Malaria Control. Malaria Fact Sheet. Nairobi: Ministry of Public Health and Sanitation; 2011.
2.
go back to reference Division of Malaria Control. 2010 Kenya MALARIA Indicator Survey. 2011. Ministry of Public Health and Sanitation, Kenya National Bureau of Statistics and ICF Macro. Division of Malaria Control. 2010 Kenya MALARIA Indicator Survey. 2011. Ministry of Public Health and Sanitation, Kenya National Bureau of Statistics and ICF Macro.
3.
go back to reference Kenya National Bureau of Statistics (KNBS) and ICF Macro. Kenya Demographic and Health Survey 2008-09. Calverton, Maryland: KNBS and ICF Macro; 2010. Kenya National Bureau of Statistics (KNBS) and ICF Macro. Kenya Demographic and Health Survey 2008-09. Calverton, Maryland: KNBS and ICF Macro; 2010.
4.
go back to reference Division of Malaria Control. National Malaria Strategy 2009-2017. Nairobi: Ministry of Public Health and Sanitation; 2009. Division of Malaria Control. National Malaria Strategy 2009-2017. Nairobi: Ministry of Public Health and Sanitation; 2009.
5.
go back to reference K’Oyugi BO. The Impact of Household and Community Level Environmental Factors on Infant and Child Mortality in Rural Kenya. 1992. Unpublished PhD Thesis, Population Studies and Research Institute, University of Nairobi. K’Oyugi BO. The Impact of Household and Community Level Environmental Factors on Infant and Child Mortality in Rural Kenya. 1992. Unpublished PhD Thesis, Population Studies and Research Institute, University of Nairobi.
6.
go back to reference Snow RW, Nahlen B, Palmer A, Donnelly CA, Gupta S, Marsh K. Risk of severe malaria among African infants: direct evidence of clinical protection during early infancy. J Infect Dis. 1998;177(3):819.CrossRefPubMed Snow RW, Nahlen B, Palmer A, Donnelly CA, Gupta S, Marsh K. Risk of severe malaria among African infants: direct evidence of clinical protection during early infancy. J Infect Dis. 1998;177(3):819.CrossRefPubMed
7.
go back to reference Amaratunga C, Lopera-Mesa TM, Brittain NJ, Cholera R, Arie T, Fujioka H, et al. A role for foetal haemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria. PLoS One. 2011;6(4):e14798.CrossRefPubMedPubMedCentral Amaratunga C, Lopera-Mesa TM, Brittain NJ, Cholera R, Arie T, Fujioka H, et al. A role for foetal haemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria. PLoS One. 2011;6(4):e14798.CrossRefPubMedPubMedCentral
8.
go back to reference McGregor IA. The development and maintenance of immunity to malaria in highly endemic arrears. Cli Trop Med Commun Dis. 1986;1:29–53. McGregor IA. The development and maintenance of immunity to malaria in highly endemic arrears. Cli Trop Med Commun Dis. 1986;1:29–53.
9.
go back to reference Colbourne MJ, Edington GM. Mortality from malaria in Accra. J Trop Med Hyg. 1954;57(9):203.PubMed Colbourne MJ, Edington GM. Mortality from malaria in Accra. J Trop Med Hyg. 1954;57(9):203.PubMed
10.
go back to reference Garnham PCC. Malaria immunity in Africans: effects in infancy and early childhood. Ann Trop Med Parasitol. 1949;43:47–61.CrossRefPubMed Garnham PCC. Malaria immunity in Africans: effects in infancy and early childhood. Ann Trop Med Parasitol. 1949;43:47–61.CrossRefPubMed
11.
go back to reference Macdonald G. The analysis of malaria parasite rates in infants. Trop Dis Bull. 1950;47(10):915.PubMed Macdonald G. The analysis of malaria parasite rates in infants. Trop Dis Bull. 1950;47(10):915.PubMed
12.
go back to reference Payne D, Grab B, Fontaine RE, Hempel JHG. Impact of control measures on malaria transmission and general mortality. Bull World Health Organ. 1976;54(4):369.PubMedPubMedCentral Payne D, Grab B, Fontaine RE, Hempel JHG. Impact of control measures on malaria transmission and general mortality. Bull World Health Organ. 1976;54(4):369.PubMedPubMedCentral
13.
go back to reference Alonso PL, Lindsay SW, Armstrong JRM, de Francisco A, Shenton FC, Greenwood BM, et al. The effect of insecticide-treated bed nets on mortality of Gambian children. Lancet. 1991;337(8756):1499–502.CrossRefPubMed Alonso PL, Lindsay SW, Armstrong JRM, de Francisco A, Shenton FC, Greenwood BM, et al. The effect of insecticide-treated bed nets on mortality of Gambian children. Lancet. 1991;337(8756):1499–502.CrossRefPubMed
14.
go back to reference Otten M, Aregawi M, Were W, Karema C, Medin A, Korenromp W, et al. Initial evidence of reduction of malaria cases and deaths in Rwanda and Ethiopia due to rapid scale-up of malaria prevention and treatment. Malar J. 2009;8:14.CrossRefPubMedPubMedCentral Otten M, Aregawi M, Were W, Karema C, Medin A, Korenromp W, et al. Initial evidence of reduction of malaria cases and deaths in Rwanda and Ethiopia due to rapid scale-up of malaria prevention and treatment. Malar J. 2009;8:14.CrossRefPubMedPubMedCentral
15.
go back to reference Aregawi MW, Ali AS, Al-mafazy A, Molteni F, Katikiti S, Warsame M, et al. Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008. Malar J. 2011;10(1):46.CrossRefPubMedPubMedCentral Aregawi MW, Ali AS, Al-mafazy A, Molteni F, Katikiti S, Warsame M, et al. Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008. Malar J. 2011;10(1):46.CrossRefPubMedPubMedCentral
16.
go back to reference Okiro EA, Hay SI, Gikandi PW, Sharif SK, Noor AM, Peshu N, et al. The decline in pediatric malaria admissions on the coast of Kenya. Malar J. 2007;6(1):151.CrossRefPubMedPubMedCentral Okiro EA, Hay SI, Gikandi PW, Sharif SK, Noor AM, Peshu N, et al. The decline in pediatric malaria admissions on the coast of Kenya. Malar J. 2007;6(1):151.CrossRefPubMedPubMedCentral
17.
go back to reference O’Meara WP, Bejon P, Mwangi TW, Okiro EA, Peshu N, Snow RW, et al. Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya. Lancet. 2008;372(9649):1555–62.CrossRefPubMedPubMedCentral O’Meara WP, Bejon P, Mwangi TW, Okiro EA, Peshu N, Snow RW, et al. Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya. Lancet. 2008;372(9649):1555–62.CrossRefPubMedPubMedCentral
19.
go back to reference Pathania V. The impact of malaria control on infant mortality in Kenya. Econ Dev Cult Chang. 2014;62(3):459–87.CrossRef Pathania V. The impact of malaria control on infant mortality in Kenya. Econ Dev Cult Chang. 2014;62(3):459–87.CrossRef
21.
go back to reference Moultrie TA, Dorrington RE, Hill AG, Hill K, Timaeus IM, Zaba B. Tools for Demographic Estimation. Paris: International Union for Scientific Study of Population demographicestimation.iussp.org; 2013. ISBN 978-0-620-57491-4. Moultrie TA, Dorrington RE, Hill AG, Hill K, Timaeus IM, Zaba B. Tools for Demographic Estimation. Paris: International Union for Scientific Study of Population demographicestimation.iussp.org; 2013. ISBN 978-0-620-57491-4.
22.
go back to reference Lawless JF. Statistical Models and Methods for Lifetime Data. Wiley series in probability and mathematical statistics, University of Waterloo, USA. 1982. ISBN 0-471-08544-8. Lawless JF. Statistical Models and Methods for Lifetime Data. Wiley series in probability and mathematical statistics, University of Waterloo, USA. 1982. ISBN 0-471-08544-8.
23.
go back to reference K’Oyugi BO. Access to child health care, medical treatment of sick children and childhood mortality relationships in Kenya. Health. 2014;6:1152–64.CrossRef K’Oyugi BO. Access to child health care, medical treatment of sick children and childhood mortality relationships in Kenya. Health. 2014;6:1152–64.CrossRef
24.
go back to reference Mosley WH, Chen LC. An analytical framework for the study of child survival in developing countries. Popul Dev Rev. 1984;10:25–45.CrossRef Mosley WH, Chen LC. An analytical framework for the study of child survival in developing countries. Popul Dev Rev. 1984;10:25–45.CrossRef
Metadata
Title
Effects of bed nets and anti-malaria drugs use on childhood mortality in Kenya’s malaria endemic and epidemic areas
Author
Boniface O K’Oyugi
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-1398-x

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