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BMC Psychiatry
Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Case report

Duloxetine-induced rapid eye movement sleep behavior disorder: a case report

Authors: Lu Tan, Junying Zhou, Linghui Yang, Rong Ren, Ye Zhang, Taomei Li, Xiangdong Tang

Published in: BMC Psychiatry | Issue 1/2017

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Abstract

Background

Tricyclic antidepressants and selective serotonin reuptake inhibitors have been reported to induce the symptoms of rapid eye movement (REM) sleep behavior disorder (RBD) or to exacerbate REM sleep without atonia. With this case report, we found an association between typical RBD and duloxetine, a serotonin-noradrenaline reuptake inhibitor.

Case presentation

We present a case of a 62-year-old woman who experienced enactment behaviors with violent dreams that were associated with increased tonic or phasic chin electromyography activity during REM sleep after treated with duloxetine. RBD symptoms were gradually reduced and completely ceased after discontinuation of duloxetine for 37 days.

Conclusion

The current case appears to be the first observation of duloxetine-induced RBD. We describe features of RBD induced by duloxetine that are similar and different from that induced by tricyclic antidepressants and selective serotonin reuptake inhibitors.
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Metadata
Title
Duloxetine-induced rapid eye movement sleep behavior disorder: a case report
Authors
Lu Tan
Junying Zhou
Linghui Yang
Rong Ren
Ye Zhang
Taomei Li
Xiangdong Tang
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1535-4

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