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Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Research article

eHealth interventions for the prevention of depression and anxiety in the general population: a systematic review and meta-analysis

Authors: M. Deady, I. Choi, R. A. Calvo, N. Glozier, H. Christensen, S. B. Harvey

Published in: BMC Psychiatry | Issue 1/2017

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Abstract

Background

Anxiety and depression are associated with a range of adverse outcomes and represent a large global burden to individuals and health care systems. Prevention programs are an important way to avert a proportion of the burden associated with such conditions both at a clinical and subclinical level. eHealth interventions provide an opportunity to offer accessible, acceptable, easily disseminated globally low-cost interventions on a wide scale. However, the efficacy of these programs remains unclear. The aim of this study is to review and evaluate the effects of eHealth prevention interventions for anxiety and depression.

Method

A systematic search was conducted on four relevant databases to identify randomized controlled trials of eHealth interventions aimed at the prevention of anxiety and depression in the general population published between 2000 and January 2016. The quality of studies was assessed and a meta-analysis was performed using pooled effect size estimates obtained from a random effects model.

Results

Ten trials were included in the systematic review and meta-analysis. All studies were of sufficient quality and utilized cognitive behavioural techniques. At post-treatment, the overall mean difference between the intervention and control groups was 0.25 (95% confidence internal: 0.09, 0.41; p = 0.003) for depression outcome studies and 0.31 (95% CI: 0.10, 0.52; p = 0.004) for anxiety outcome studies, indicating a small but positive effect of the eHealth interventions. The effect sizes for universal and indicated/selective interventions were similar (0.29 and 0.25 respectively). However, there was inadequate evidence to suggest that such interventions have an effect on long-term disorder incidence rates.

Conclusions

Evidence suggests that eHealth prevention interventions for anxiety and depression are associated with small but positive effects on symptom reduction. However, there is inadequate evidence on the medium to long-term effect of such interventions, and importantly, on the reduction of incidence of disorders. Further work to explore the impact of eHealth psychological interventions on long-term incidence rates.
Literature
1.
go back to reference Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):593–602.CrossRefPubMed Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005;62(6):593–602.CrossRefPubMed
2.
go back to reference Demyttenaere K, Bruffaerts R, Posada-Villa J, Gasquet I, Kovess V, Lepine JP, Angermeyer MC, Bernert S, de Girolamo G, Morosini P, et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization world mental health surveys. Jama-J Am Med Assoc. 2004;291(21):2581–90.CrossRef Demyttenaere K, Bruffaerts R, Posada-Villa J, Gasquet I, Kovess V, Lepine JP, Angermeyer MC, Bernert S, de Girolamo G, Morosini P, et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization world mental health surveys. Jama-J Am Med Assoc. 2004;291(21):2581–90.CrossRef
3.
go back to reference Saarni SI, Suvisaari J, Sintonen H, Pirkola S, Koskinen S, Aromaa A, Lönnqvist J. Impact of psychiatric disorders on health-related quality of life: general population survey. Br J Psychiatry. 2007;190:326–32.CrossRefPubMed Saarni SI, Suvisaari J, Sintonen H, Pirkola S, Koskinen S, Aromaa A, Lönnqvist J. Impact of psychiatric disorders on health-related quality of life: general population survey. Br J Psychiatry. 2007;190:326–32.CrossRefPubMed
4.
go back to reference Cuijpers P, Smit F. Excess mortality in depression: a meta-analysis of community studies. J Affect Disord. 2002;72:227–36.CrossRefPubMed Cuijpers P, Smit F. Excess mortality in depression: a meta-analysis of community studies. J Affect Disord. 2002;72:227–36.CrossRefPubMed
5.
go back to reference Berto P, D’Ilario D, Ruffo P, Di Virgilio R, Rizzo F. Depression: cost-of-illness studies in the international literature: a review. J Ment Health Policy Econ. 2000;3:3–10.CrossRefPubMed Berto P, D’Ilario D, Ruffo P, Di Virgilio R, Rizzo F. Depression: cost-of-illness studies in the international literature: a review. J Ment Health Policy Econ. 2000;3:3–10.CrossRefPubMed
6.
go back to reference Greenberg PE, Birnbaum HG. The economic burden of depression in the US: societal and patient perspectives. Expert Opin Pharmacother. 2005;6:369–76.CrossRefPubMed Greenberg PE, Birnbaum HG. The economic burden of depression in the US: societal and patient perspectives. Expert Opin Pharmacother. 2005;6:369–76.CrossRefPubMed
7.
go back to reference Smit F, Cuijpers P, Oostenbrink J, Batelaan N, de Graaf R, Beekman A. Excess costs of common mental disorders: population-based cohort study. J Ment Health Policy Econ. 2006;9:193–200.PubMed Smit F, Cuijpers P, Oostenbrink J, Batelaan N, de Graaf R, Beekman A. Excess costs of common mental disorders: population-based cohort study. J Ment Health Policy Econ. 2006;9:193–200.PubMed
10.
go back to reference Andrews G, Issakidis C, Sanderson K, Corry J, Lapsley H. Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders. Br J Psychiatry. 2004;184:526–33.CrossRefPubMed Andrews G, Issakidis C, Sanderson K, Corry J, Lapsley H. Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders. Br J Psychiatry. 2004;184:526–33.CrossRefPubMed
11.
go back to reference Hickie IB. Preventing depression: a challenge for the Australian community. Med J Aust. 2002;177(Suppl):S85–6.PubMed Hickie IB. Preventing depression: a challenge for the Australian community. Med J Aust. 2002;177(Suppl):S85–6.PubMed
12.
go back to reference Berkels H, Henderson J, Henke N, Kuhn K, Lavikainen J, Lehtinen V, Ozamiz A, Van den Heede P, Zenzinger K. Mental health promotion and prevention strategies for coping with anxiety, depression and stress related disorders in Europe. In. Dortmund: European Commission; 2004. Berkels H, Henderson J, Henke N, Kuhn K, Lavikainen J, Lehtinen V, Ozamiz A, Van den Heede P, Zenzinger K. Mental health promotion and prevention strategies for coping with anxiety, depression and stress related disorders in Europe. In. Dortmund: European Commission; 2004.
13.
go back to reference Cuijpers P. Examining the effects of prevention programs on the incidence of new cases of mental disorders: the lack of statistical power. Am J Psychiatry. 2003;160(8):1385–91.CrossRefPubMed Cuijpers P. Examining the effects of prevention programs on the incidence of new cases of mental disorders: the lack of statistical power. Am J Psychiatry. 2003;160(8):1385–91.CrossRefPubMed
14.
go back to reference Andrews G, Wilkinson DD. The prevention of mental disorders in young people. Med J Aust. 2002;177(Suppl):S97–S100.PubMed Andrews G, Wilkinson DD. The prevention of mental disorders in young people. Med J Aust. 2002;177(Suppl):S97–S100.PubMed
15.
go back to reference Cuijpers P, Beekman AT, Reynolds CF. Preventing depression: a global priority. J Am Med Assoc. 2012;307:1033–4.CrossRef Cuijpers P, Beekman AT, Reynolds CF. Preventing depression: a global priority. J Am Med Assoc. 2012;307:1033–4.CrossRef
17.
go back to reference Cuijpers P, van Straten A, Smit F, Mihalopoulos C, Beekman A. Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. Am J Psychiatr. 2008;165:1272–80.CrossRefPubMed Cuijpers P, van Straten A, Smit F, Mihalopoulos C, Beekman A. Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. Am J Psychiatr. 2008;165:1272–80.CrossRefPubMed
18.
go back to reference van't Veer-Tazelaar P, van Marwijk H, van Oppen P, van der Horst H, Smit F, Cuijpers P, Beekman A. Prevention of late-life anxiety and depression has sustained effects over 24 months: a pragmatic randomized trial. Am J Geriatr Psychiatr. 2011;19(3):230–9.CrossRef van't Veer-Tazelaar P, van Marwijk H, van Oppen P, van der Horst H, Smit F, Cuijpers P, Beekman A. Prevention of late-life anxiety and depression has sustained effects over 24 months: a pragmatic randomized trial. Am J Geriatr Psychiatr. 2011;19(3):230–9.CrossRef
19.
go back to reference van Zoonen K, Buntrock C, Ebert DD, Smit F, Reynolds CF, Beekman ATF, Cuijpers P. Preventing the onset of major depressive disorder: a meta-analytic review of psychological interventions. Int J Epidemiol. 2014;43(2):318–29.CrossRefPubMedPubMedCentral van Zoonen K, Buntrock C, Ebert DD, Smit F, Reynolds CF, Beekman ATF, Cuijpers P. Preventing the onset of major depressive disorder: a meta-analytic review of psychological interventions. Int J Epidemiol. 2014;43(2):318–29.CrossRefPubMedPubMedCentral
20.
go back to reference Andrews G, Cuijpers P, Craske MG, McEvoy P, Titov N. Computer therapy for the anxiety and depressive disorders is effective, acceptable and practical health care: a meta-analysis. PLoS One. 2010;5(10):e13196.CrossRefPubMedPubMedCentral Andrews G, Cuijpers P, Craske MG, McEvoy P, Titov N. Computer therapy for the anxiety and depressive disorders is effective, acceptable and practical health care: a meta-analysis. PLoS One. 2010;5(10):e13196.CrossRefPubMedPubMedCentral
21.
go back to reference Richards D, Richardson T. Computer-based psychological treatments for depression: a systematic review and meta-analysis. Clin Psychol Rev. 2012;32:329–42.CrossRefPubMed Richards D, Richardson T. Computer-based psychological treatments for depression: a systematic review and meta-analysis. Clin Psychol Rev. 2012;32:329–42.CrossRefPubMed
22.
go back to reference Andersson G, Cuijpers P. Internet-based and other computerized psychological treatments for adult depression: a meta-analysis. Cogn Behav Ther. 2009;38:196–205.CrossRefPubMed Andersson G, Cuijpers P. Internet-based and other computerized psychological treatments for adult depression: a meta-analysis. Cogn Behav Ther. 2009;38:196–205.CrossRefPubMed
23.
go back to reference So M, Yamaguchi S, Hashimoto S, Sado M, Furukawa TA, McCrone P. Is computerised CBT really helpful for adult depression?-a meta-analytic re-evaluation of CCBT for adult depression in terms of clinical implementation and methodological validity. BMC Psychiatry. 2013;13(1):1–14.CrossRef So M, Yamaguchi S, Hashimoto S, Sado M, Furukawa TA, McCrone P. Is computerised CBT really helpful for adult depression?-a meta-analytic re-evaluation of CCBT for adult depression in terms of clinical implementation and methodological validity. BMC Psychiatry. 2013;13(1):1–14.CrossRef
24.
go back to reference Spek V, Cuijpers P, Nyklicek I, Riper H, Keyzer J, Pop V. Internet-based cognitive behaviour therapy for symptoms of depression and anxiety: a meta-analysis. Psychol Med. 2007;37(3):319–28.CrossRefPubMed Spek V, Cuijpers P, Nyklicek I, Riper H, Keyzer J, Pop V. Internet-based cognitive behaviour therapy for symptoms of depression and anxiety: a meta-analysis. Psychol Med. 2007;37(3):319–28.CrossRefPubMed
25.
go back to reference Hirai M, Clum GA. A meta-analytic study of self-help interventions for anxiety problems. Behav Ther. 2006;37:99–111.CrossRefPubMed Hirai M, Clum GA. A meta-analytic study of self-help interventions for anxiety problems. Behav Ther. 2006;37:99–111.CrossRefPubMed
26.
27.
go back to reference Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.CrossRefPubMedPubMedCentral Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.CrossRefPubMedPubMedCentral
28.
go back to reference Griffiths KM, Farrer L, Christensen H. The efficacy of internet interventions for depression and anxiety disorders: a review of randomised controlled trials. Med J Aust. 2010;192(11 Suppl):S4–11.PubMed Griffiths KM, Farrer L, Christensen H. The efficacy of internet interventions for depression and anxiety disorders: a review of randomised controlled trials. Med J Aust. 2010;192(11 Suppl):S4–11.PubMed
29.
go back to reference StataCorp. Stata Statistical Software: Release 12. In. College Station, TX: StataCorp LP; 2011. StataCorp. Stata Statistical Software: Release 12. In. College Station, TX: StataCorp LP; 2011.
30.
go back to reference Downs S, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health. 1998;52:377–84.CrossRefPubMedPubMedCentral Downs S, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health. 1998;52:377–84.CrossRefPubMedPubMedCentral
31.
go back to reference Olivo S, Macedo L, Gadotti I, Fuentes J, Stanton T, Magee D. Scales to assess the quality of randomized controlled trials: a systematic review. Phys Ther. 2008;88:156–75.CrossRefPubMed Olivo S, Macedo L, Gadotti I, Fuentes J, Stanton T, Magee D. Scales to assess the quality of randomized controlled trials: a systematic review. Phys Ther. 2008;88:156–75.CrossRefPubMed
32.
go back to reference Nieuwenhuijsen K, Bültmann U, Neumeyer-Gromen A, Verhoeven A, Verbeek J, van der Feltz-Cornelis C. Interventions to improve occupational health in depressed people. Cochrane Database Syst Rev. 2008:CD006237. Nieuwenhuijsen K, Bültmann U, Neumeyer-Gromen A, Verhoeven A, Verbeek J, van der Feltz-Cornelis C. Interventions to improve occupational health in depressed people. Cochrane Database Syst Rev. 2008:CD006237.
33.
go back to reference Tan L, Wang M-J, Modini M, Joyce S, Mykletun A, Christensen H, Harvey SB. Preventing the development of depression at work: a systematic review and meta-analysis of universal interventions in the workplace. BMC Med. 2014;12:74.CrossRefPubMedPubMedCentral Tan L, Wang M-J, Modini M, Joyce S, Mykletun A, Christensen H, Harvey SB. Preventing the development of depression at work: a systematic review and meta-analysis of universal interventions in the workplace. BMC Med. 2014;12:74.CrossRefPubMedPubMedCentral
34.
go back to reference Samoocha D, Bruinvels D, Elbers N, Anema J, van der Beek A. Effectiveness of web-based interventions on patient empowerment: a systematic review and meta-analysis. J Med Internet Res. 2010;12:e23–10.CrossRefPubMedPubMedCentral Samoocha D, Bruinvels D, Elbers N, Anema J, van der Beek A. Effectiveness of web-based interventions on patient empowerment: a systematic review and meta-analysis. J Med Internet Res. 2010;12:e23–10.CrossRefPubMedPubMedCentral
35.
go back to reference Cohen J. Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Lawrence Erlbaum Associates; 1988. Cohen J. Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Lawrence Erlbaum Associates; 1988.
36.
go back to reference Deeks J, Higgins J, Altman D. Analysing data and undertaking meta-analyses. In: Cochrane Handbook for Systematic Reviews of Interventions Version 510. edn. Edited by Higgins J, Green S: The Cochrane Collaboration; 2011. Deeks J, Higgins J, Altman D. Analysing data and undertaking meta-analyses. In: Cochrane Handbook for Systematic Reviews of Interventions Version 510. edn. Edited by Higgins J, Green S: The Cochrane Collaboration; 2011.
37.
go back to reference Sutton AJ, Abrams KR, Jones DR. An illustrated guide to the methods of meta-analysis. J Eval Clin Pract. 2001;7(2):135–48.CrossRefPubMed Sutton AJ, Abrams KR, Jones DR. An illustrated guide to the methods of meta-analysis. J Eval Clin Pract. 2001;7(2):135–48.CrossRefPubMed
38.
go back to reference Higgins J, Thompson S, Deeks J, Altman D. Measuring inconsistency in meta-analyses. Br Med J. 2003;327:557–60.CrossRef Higgins J, Thompson S, Deeks J, Altman D. Measuring inconsistency in meta-analyses. Br Med J. 2003;327:557–60.CrossRef
39.
go back to reference Dickersin K. The existence of publication bias and risk factors for its occurrence. JAMA. 1990;263:1385–9.CrossRefPubMed Dickersin K. The existence of publication bias and risk factors for its occurrence. JAMA. 1990;263:1385–9.CrossRefPubMed
40.
go back to reference Spek V, Cuijpers P, Nyklicek I, Smits N, Riper H, Keyzer J, Pop V. One-year follow-up results of a randomized controlled clinical trial on internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years. Psychol Med. 2008;38(5):635–9.CrossRefPubMed Spek V, Cuijpers P, Nyklicek I, Smits N, Riper H, Keyzer J, Pop V. One-year follow-up results of a randomized controlled clinical trial on internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years. Psychol Med. 2008;38(5):635–9.CrossRefPubMed
41.
go back to reference Buntrock C, Ebert D, Lehr D, et al. Effect of a web-based guided self-help intervention for prevention of major depression in adults with subthreshold depression: a randomized clinical trial. JAMA. 2016;315(17):1854–63.CrossRefPubMed Buntrock C, Ebert D, Lehr D, et al. Effect of a web-based guided self-help intervention for prevention of major depression in adults with subthreshold depression: a randomized clinical trial. JAMA. 2016;315(17):1854–63.CrossRefPubMed
42.
go back to reference Buntrock C, Ebert D, Lehr D, Riper H, Smit F, Cuijpers P, Berking M. Effectiveness of a web-based cognitive behavioural intervention for subthreshold depression: pragmatic randomised controlled trial. Psychother Psychosom. 2015;84(6):348–358. Buntrock C, Ebert D, Lehr D, Riper H, Smit F, Cuijpers P, Berking M. Effectiveness of a web-based cognitive behavioural intervention for subthreshold depression: pragmatic randomised controlled trial. Psychother Psychosom. 2015;84(6):348–358.
43.
go back to reference Christensen H, Batterham P, Mackinnon A, Griffiths KM, Hehir KK, Kenardy J, Gosling J, Bennett K. Prevention of generalized anxiety disorder using a web intervention, iChill: randomized controlled trial. J Med Internet Res. 2014;16(9):176–89.CrossRef Christensen H, Batterham P, Mackinnon A, Griffiths KM, Hehir KK, Kenardy J, Gosling J, Bennett K. Prevention of generalized anxiety disorder using a web intervention, iChill: randomized controlled trial. J Med Internet Res. 2014;16(9):176–89.CrossRef
44.
go back to reference Imamura K, Kawakami N, Furukawa TA, Matsuyama Y, Shimazu A, Umanodan R, Kawakami S, Kasai K. Effects of an internet-based cognitive behavioral therapy (iCBT) program in Manga format on improving subthreshold depressive symptoms among healthy workers: A randomized controlled trial. PLoS One. 2014;9(5):e97167.CrossRefPubMedPubMedCentral Imamura K, Kawakami N, Furukawa TA, Matsuyama Y, Shimazu A, Umanodan R, Kawakami S, Kasai K. Effects of an internet-based cognitive behavioral therapy (iCBT) program in Manga format on improving subthreshold depressive symptoms among healthy workers: A randomized controlled trial. PLoS One. 2014;9(5):e97167.CrossRefPubMedPubMedCentral
45.
go back to reference Spek V, Nyklícek I, Smits N, Cuijpers P, Riper H, Keyzer J, Pop V. Internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years old: a randomized controlled clinical trial. Psychol Med. 2007;37(12):1797–806.CrossRefPubMed Spek V, Nyklícek I, Smits N, Cuijpers P, Riper H, Keyzer J, Pop V. Internet-based cognitive behavioural therapy for subthreshold depression in people over 50 years old: a randomized controlled clinical trial. Psychol Med. 2007;37(12):1797–806.CrossRefPubMed
46.
go back to reference Clarke G, Reid E, Eubanks D, O'Connor E, DeBar LL, Kelleher C, Lynch F, Nunley S. Overcoming depression on the internet (ODIN): a randomized controlled trial of an internet depression skills intervention program. J Med Internet Res. 2002;4(3):E14.CrossRefPubMedPubMedCentral Clarke G, Reid E, Eubanks D, O'Connor E, DeBar LL, Kelleher C, Lynch F, Nunley S. Overcoming depression on the internet (ODIN): a randomized controlled trial of an internet depression skills intervention program. J Med Internet Res. 2002;4(3):E14.CrossRefPubMedPubMedCentral
47.
go back to reference Cukrowicz KCJ, Thomas E Jr. Computer-based intervention for anxious and depressive symptoms in a non-clinical population. Cogn Ther Res. 2007;31(5):677–93.CrossRef Cukrowicz KCJ, Thomas E Jr. Computer-based intervention for anxious and depressive symptoms in a non-clinical population. Cogn Ther Res. 2007;31(5):677–93.CrossRef
48.
go back to reference Levin ME, Pistorello J, Seeley JR, Hayes SC. Feasibility of a prototype web-based acceptance and commitment therapy prevention program for college students. J Am Coll Heal. 2014;62(1):20–30.CrossRef Levin ME, Pistorello J, Seeley JR, Hayes SC. Feasibility of a prototype web-based acceptance and commitment therapy prevention program for college students. J Am Coll Heal. 2014;62(1):20–30.CrossRef
49.
go back to reference Lintvedt OK, Griffiths KM, Sorensen K, Ostvik AR, Wang CE, Eisemann M, Waterloo K. Evaluating the effectiveness and efficacy of unguided internet-based self-help intervention for the prevention of depression: a randomized controlled trial. Clin Psychol Psychother. 2013;20(1):10–27.CrossRefPubMed Lintvedt OK, Griffiths KM, Sorensen K, Ostvik AR, Wang CE, Eisemann M, Waterloo K. Evaluating the effectiveness and efficacy of unguided internet-based self-help intervention for the prevention of depression: a randomized controlled trial. Clin Psychol Psychother. 2013;20(1):10–27.CrossRefPubMed
50.
go back to reference Morgan AJ, Jorm AF, Mackinnon AJ. Email-based promotion of self-help for subthreshold depression: mood memos randomised controlled trial. Br J Psychiatry. 2012;200(5):412–8.CrossRefPubMed Morgan AJ, Jorm AF, Mackinnon AJ. Email-based promotion of self-help for subthreshold depression: mood memos randomised controlled trial. Br J Psychiatry. 2012;200(5):412–8.CrossRefPubMed
51.
go back to reference Musiat P, Conrod P, Treasure J, Tylee A, Williams C, Schmidt U. Targeted prevention of common mental health disorders in university students: randomised controlled trial of a transdiagnostic trait-focused web-based intervention. PLoS One. 2014;9(4):e93621.CrossRefPubMedPubMedCentral Musiat P, Conrod P, Treasure J, Tylee A, Williams C, Schmidt U. Targeted prevention of common mental health disorders in university students: randomised controlled trial of a transdiagnostic trait-focused web-based intervention. PLoS One. 2014;9(4):e93621.CrossRefPubMedPubMedCentral
52.
go back to reference Imamura K, Kawakami N, Furukawa TA, Matsuyama Y, Shimazu A, Umanodan R, Kawakami S, Kasai K. Does internet-based cognitive behavioral therapy (iCBT) prevent major depressive episode for workers? A 12-month follow-up of a randomized controlled trial. Psychol Med. 2015;45(9):1907–17.CrossRefPubMed Imamura K, Kawakami N, Furukawa TA, Matsuyama Y, Shimazu A, Umanodan R, Kawakami S, Kasai K. Does internet-based cognitive behavioral therapy (iCBT) prevent major depressive episode for workers? A 12-month follow-up of a randomized controlled trial. Psychol Med. 2015;45(9):1907–17.CrossRefPubMed
53.
go back to reference Cuijpers P, Smit F, van Straten A. Psychological treatments of subthreshold depression: a meta-analytic review. Acta Psychiatr Scand. 2007;115(6):434–41.CrossRefPubMed Cuijpers P, Smit F, van Straten A. Psychological treatments of subthreshold depression: a meta-analytic review. Acta Psychiatr Scand. 2007;115(6):434–41.CrossRefPubMed
54.
go back to reference Cuijpers P, De Graaf R, Van Dorsselaer S: Minor depression: risk profiles, functional disability, health care use and risk of developing major depression. J Affect Disord. 2004;79:71–79. Cuijpers P, De Graaf R, Van Dorsselaer S: Minor depression: risk profiles, functional disability, health care use and risk of developing major depression. J Affect Disord. 2004;79:71–79.
55.
go back to reference Fergusson DM, Horwood LJ, Ridder EM, Beautrais AL. Subthreshold depression in adolescence and mental health outcomes in adulthood. Arch Gen Psychiatry. 2005;62:66–72.CrossRefPubMed Fergusson DM, Horwood LJ, Ridder EM, Beautrais AL. Subthreshold depression in adolescence and mental health outcomes in adulthood. Arch Gen Psychiatry. 2005;62:66–72.CrossRefPubMed
56.
go back to reference Oxman T, Sengupta A. Treatment of minor depression. Am J Geriatr Psychiatr. 2002;10:256–64.CrossRef Oxman T, Sengupta A. Treatment of minor depression. Am J Geriatr Psychiatr. 2002;10:256–64.CrossRef
57.
go back to reference Beekman A, Geerlings S, Deeg D, Smit J, Schoevers R, de Beurs E, Braam A, Penninx B, van Tilburg W. The natural history of late-life depression: a 6-year prospective study in the community. Arch Gen Psychiatry. 2002;59:605–11.CrossRefPubMed Beekman A, Geerlings S, Deeg D, Smit J, Schoevers R, de Beurs E, Braam A, Penninx B, van Tilburg W. The natural history of late-life depression: a 6-year prospective study in the community. Arch Gen Psychiatry. 2002;59:605–11.CrossRefPubMed
58.
go back to reference Rose G. The strategy of prevention medicine. Oxford: Oxford University Press; 1994. Rose G. The strategy of prevention medicine. Oxford: Oxford University Press; 1994.
59.
go back to reference Zbozinek TD, Rose RD, Wolitzky-Taylor KB, Sherbourne C, Sullivan G, Stein MB, Roy-Byrne PP, Craske MG. Diagnostic overlap of generalized anxiety disorder and major depressive disorder in a primary care sample. Depression and anxiety. 2012;29(12):1065–71.CrossRefPubMedPubMedCentral Zbozinek TD, Rose RD, Wolitzky-Taylor KB, Sherbourne C, Sullivan G, Stein MB, Roy-Byrne PP, Craske MG. Diagnostic overlap of generalized anxiety disorder and major depressive disorder in a primary care sample. Depression and anxiety. 2012;29(12):1065–71.CrossRefPubMedPubMedCentral
60.
go back to reference Johansson R, Andersson G. Internet-based psychological treatments for depression. Expert Rev Neurother. 2012;12:861–70.CrossRefPubMed Johansson R, Andersson G. Internet-based psychological treatments for depression. Expert Rev Neurother. 2012;12:861–70.CrossRefPubMed
61.
go back to reference Ryan RM, Deci EL. Self-determination theory and the facilitation of intrinsic motivation, social development and well-being. Am Psychol. 2000;55(1):68–78.CrossRefPubMed Ryan RM, Deci EL. Self-determination theory and the facilitation of intrinsic motivation, social development and well-being. Am Psychol. 2000;55(1):68–78.CrossRefPubMed
62.
go back to reference Donker T, Batterham PJ, Warmerdam L, Bennett K, Bennett A, Cuijpers P, Griffiths KM, Christensen H. Predictors and moderators of response to internet-delivered interpersonal psychotherapy and cognitive behavior therapy for depression. J Affect Disord. 2013;151(1):343–51.CrossRefPubMed Donker T, Batterham PJ, Warmerdam L, Bennett K, Bennett A, Cuijpers P, Griffiths KM, Christensen H. Predictors and moderators of response to internet-delivered interpersonal psychotherapy and cognitive behavior therapy for depression. J Affect Disord. 2013;151(1):343–51.CrossRefPubMed
63.
go back to reference Leykin Y, Muñoz RF, Contreras O, Latham MD. Results from a trial of an unsupported internet intervention for depressive symptoms. Internet Interventions. 2014;1(4):175–81.CrossRefPubMedPubMedCentral Leykin Y, Muñoz RF, Contreras O, Latham MD. Results from a trial of an unsupported internet intervention for depressive symptoms. Internet Interventions. 2014;1(4):175–81.CrossRefPubMedPubMedCentral
64.
go back to reference Sheffield JK, Spence SH, Rapee RM, Kowalenko N, Wignall A, Davis A, McLoone J. Evaluation of universal, indicated, and combined cognitive-behavioral approaches to the prevention of depression among adolescents. J Consult Clin Psychol. 2006;74(1):66–79.CrossRefPubMed Sheffield JK, Spence SH, Rapee RM, Kowalenko N, Wignall A, Davis A, McLoone J. Evaluation of universal, indicated, and combined cognitive-behavioral approaches to the prevention of depression among adolescents. J Consult Clin Psychol. 2006;74(1):66–79.CrossRefPubMed
65.
go back to reference Merry S, McDowell H, Wild CJ, Bir J, Cunliffe R. A randomized placebo-controlled trial of a school-based depression prevention program. J Am Acad Child Adolesc Psychiatry. 2004;43:538–47.CrossRefPubMed Merry S, McDowell H, Wild CJ, Bir J, Cunliffe R. A randomized placebo-controlled trial of a school-based depression prevention program. J Am Acad Child Adolesc Psychiatry. 2004;43:538–47.CrossRefPubMed
66.
go back to reference Muñoz RF, Cuijpers P, Smit F, Barrera AZ, Leykin Y. Prevention of major depression. Annu Rev Clin Psychol. 2010;6:181–212.CrossRefPubMed Muñoz RF, Cuijpers P, Smit F, Barrera AZ, Leykin Y. Prevention of major depression. Annu Rev Clin Psychol. 2010;6:181–212.CrossRefPubMed
67.
go back to reference Cuijpers P. Examining the effects of prevention programs on the incidence of new cases of mental disorders: the lack of statistical power. Am J Psychiatr. 2003;160(8):1385–91.CrossRefPubMed Cuijpers P. Examining the effects of prevention programs on the incidence of new cases of mental disorders: the lack of statistical power. Am J Psychiatr. 2003;160(8):1385–91.CrossRefPubMed
68.
go back to reference Jane-Llopis E, Hosman C, Jenkins R, Anderson P. Predictors of efficacy in depression prevention programmes: meta-analysis. Br J Psychiatry. 2003;183:384–97.CrossRefPubMed Jane-Llopis E, Hosman C, Jenkins R, Anderson P. Predictors of efficacy in depression prevention programmes: meta-analysis. Br J Psychiatry. 2003;183:384–97.CrossRefPubMed
69.
go back to reference Cuijpers P, Van Straten A, Smit F. Preventing the incidence of new cases of mental disorders: a meta-analytic review. J Nerv Ment Dis. 2005;193:119–25.CrossRefPubMed Cuijpers P, Van Straten A, Smit F. Preventing the incidence of new cases of mental disorders: a meta-analytic review. J Nerv Ment Dis. 2005;193:119–25.CrossRefPubMed
70.
go back to reference Calvo RA, Peters D. Positive computing: technology for wellbeing and human potential. Cambridge: MIT Press; 2014. Calvo RA, Peters D. Positive computing: technology for wellbeing and human potential. Cambridge: MIT Press; 2014.
71.
go back to reference Ghandeharioun A, Azaria A, Taylor S, Picard RW. “Kind and grateful”: a context-sensitive smartphone app utilizing inspirational content to promote gratitude. Psychology of Well-Being. 2016;6(1):1–21.CrossRef Ghandeharioun A, Azaria A, Taylor S, Picard RW. “Kind and grateful”: a context-sensitive smartphone app utilizing inspirational content to promote gratitude. Psychology of Well-Being. 2016;6(1):1–21.CrossRef
72.
go back to reference Kramer ADI, Guillory JE, Hancock JT. Experimental evidence of massive-scale emotional contagion through social networks. Proc Natl Acad Sci. 2014;111(24):8788–90.CrossRefPubMedPubMedCentral Kramer ADI, Guillory JE, Hancock JT. Experimental evidence of massive-scale emotional contagion through social networks. Proc Natl Acad Sci. 2014;111(24):8788–90.CrossRefPubMedPubMedCentral
73.
go back to reference Hotopf M, Mehta N, Henderson M, Wessely S. Wellbeing interventions: no evidence they prevent mental illness. Lancet. 2015;386(9996):852–3.CrossRefPubMed Hotopf M, Mehta N, Henderson M, Wessely S. Wellbeing interventions: no evidence they prevent mental illness. Lancet. 2015;386(9996):852–3.CrossRefPubMed
74.
go back to reference O'Kearney R, Gibson M, Christensen H, Griffiths KM. Effects of a cognitive-behavioural internet program on depression, vulnerability to depression and stigma in adolescent males: a school-based controlled trial. Cogn Behav Ther. 2006;35(1):43–54.CrossRefPubMed O'Kearney R, Gibson M, Christensen H, Griffiths KM. Effects of a cognitive-behavioural internet program on depression, vulnerability to depression and stigma in adolescent males: a school-based controlled trial. Cogn Behav Ther. 2006;35(1):43–54.CrossRefPubMed
75.
go back to reference O'Kearney R, Kang K, Christensen H, Griffiths K. A controlled trial of a school-based internet program for reducing depressive symptoms in adolescent girls. Depression & Anxiety. 2009;26(1):65–72.CrossRefPubMed O'Kearney R, Kang K, Christensen H, Griffiths K. A controlled trial of a school-based internet program for reducing depressive symptoms in adolescent girls. Depression & Anxiety. 2009;26(1):65–72.CrossRefPubMed
76.
go back to reference Newton NC, Teesson M, Vogl LE, Andrews G. Internet-based prevention for alcohol and cannabis use: final results of the climate schools course. Addiction. 2010;105(4):749–59.CrossRefPubMed Newton NC, Teesson M, Vogl LE, Andrews G. Internet-based prevention for alcohol and cannabis use: final results of the climate schools course. Addiction. 2010;105(4):749–59.CrossRefPubMed
77.
go back to reference Neil AL, Christensen H. Efficacy and effectiveness of school-based prevention and early intervention programs for anxiety. Clin Psychol Rev. 2009;29(3):208–15.CrossRefPubMed Neil AL, Christensen H. Efficacy and effectiveness of school-based prevention and early intervention programs for anxiety. Clin Psychol Rev. 2009;29(3):208–15.CrossRefPubMed
78.
go back to reference Mykletun A, Harvey SB. Prevention of mental disorders: a new era for workplace mental health. Occup Environ Med. 2012;69(12):868–9.CrossRefPubMed Mykletun A, Harvey SB. Prevention of mental disorders: a new era for workplace mental health. Occup Environ Med. 2012;69(12):868–9.CrossRefPubMed
Metadata
Title
eHealth interventions for the prevention of depression and anxiety in the general population: a systematic review and meta-analysis
Authors
M. Deady
I. Choi
R. A. Calvo
N. Glozier
H. Christensen
S. B. Harvey
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1473-1

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