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Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Study protocol

The PED-t trial protocol: The effect of physical exercise –and dietary therapy compared with cognitive behavior therapy in treatment of bulimia nervosa and binge eating disorder

Authors: Therese Fostervold Mathisen, Jan H. Rosenvinge, Gunn Pettersen, Oddgeir Friborg, KariAnne Vrabel, Solfrid Bratland-Sanda, Mette Svendsen, Trine Stensrud, Maria Bakland, Rolf Wynn, Jorunn Sundgot-Borgen

Published in: BMC Psychiatry | Issue 1/2017

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Abstract

Background

Sufferers from bulimia nervosa (BN) and binge eating disorder (BED) underestimate the severity risk of their illness and, therefore, postpone seeking professional help for years. Moreover, less than one in five actually seek professional help and only 50% respond to current treatments, such as cognitive behavioral therapy (CBT). The impetus for the present trial is to explore a novel combination treatment approach adapted from physical exercise- and dietary therapy (PED-t). The therapeutic underpinnings of these separate treatment components are well-known, but their combination to treat BN and BED have never been previously tested. The purpose of this paper is to provide the rationale for this new treatment approach and to outline the specific methods and procedures.

Methods

The PED-t trial uses a prospective randomized controlled design. It allocates women between 18 and 40 years (BMI range 17.5–35.0) to groups consisting of 5–8 members who receive either CBT or PED-t for 16 weeks. Excess participants are allocated to a waiting list control group condition. All participants are assessed at baseline, post-treatment, 6, 12 and 24 months’ post-follow-up, respectively, and monitored for changes in biological, psychological and therapy process variables. The primary outcome relates to the ED symptom severity, while secondary outcomes relates to treatment effects on physical health, treatment satisfaction, therapeutic alliance, and cost-effectiveness. We aim to disseminate the results in high-impact journals, preferable open access, and at international conferences.

Discussion

We expect that the new treatment will perform equal to CBT in terms of behavioral and psychological symptoms, but better in terms of reducing somatic symptoms and complications. We also expect that the new treatment will improve physical fitness and thereby, quality of life. Hence, the new treatment will add to the portfolio of evidence-based therapies and thereby provide a good treatment alternative for females with BN and BED.

Trial registration

Prospectively registered in REC the 16th of December 2013 with the identifier number 2013/​1871, and in Clinical Trials the 17th of February 2014 with the identifier number NCT02079935.
Literature
1.
go back to reference Raevuori A, Suokas J, Haukka J, Gissler M, Linna M, Grainger M, Suvisaari J. Highly increased risk of type 2 diabetes in patients with binge eating disorder and bulimia nervosa. Int J Eat Disord. 2015;48(6):555–62. Raevuori A, Suokas J, Haukka J, Gissler M, Linna M, Grainger M, Suvisaari J. Highly increased risk of type 2 diabetes in patients with binge eating disorder and bulimia nervosa. Int J Eat Disord. 2015;48(6):555–62.
2.
go back to reference Sullivan PF, Gendall KA, Bulik CM, Carter FA, Joyce PR. Elevated total cholesterol in bulimia nervosa. Int J Eat Disord. 1998;23:425–32.CrossRefPubMed Sullivan PF, Gendall KA, Bulik CM, Carter FA, Joyce PR. Elevated total cholesterol in bulimia nervosa. Int J Eat Disord. 1998;23:425–32.CrossRefPubMed
3.
go back to reference Monteleone P, Santonastaso P, Pannuto M, Favaro A, Caregaro L, Castaldo E, Zanetti T, Maj M. Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variables. Psychiatry Res. 2005;134:267–73.CrossRefPubMed Monteleone P, Santonastaso P, Pannuto M, Favaro A, Caregaro L, Castaldo E, Zanetti T, Maj M. Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variables. Psychiatry Res. 2005;134:267–73.CrossRefPubMed
4.
go back to reference Gendall KA, Joyce PR, Carter FA, McIntosh VV, Bulik CM. The effect of bulimia nervosa on plasma glucose and lipids. Physiol Behav. 2002;77:99–105.CrossRefPubMed Gendall KA, Joyce PR, Carter FA, McIntosh VV, Bulik CM. The effect of bulimia nervosa on plasma glucose and lipids. Physiol Behav. 2002;77:99–105.CrossRefPubMed
6.
go back to reference Mountjoy M, Sundgot-Borgen J, Burke L, Carter S, Constantini N, Lebrun C, Meyer N, Sherman R, Steffen K, Budgett R, Ljungqvist A. The IOC consensus statement: beyond the female athlete triad--relative energy deficiency in sport (RED-S)s Br J Sports Med 2014;48:491–497. Mountjoy M, Sundgot-Borgen J, Burke L, Carter S, Constantini N, Lebrun C, Meyer N, Sherman R, Steffen K, Budgett R, Ljungqvist A. The IOC consensus statement: beyond the female athlete triad--relative energy deficiency in sport (RED-S)s Br J Sports Med 2014;48:491–497.
7.
go back to reference Melin A, Tornberg AB, Skouby S, Moller SS, Sundgot-Borgen J. Faber J. Aziz M, Sjodin A. Energy availability and the female athlete triad in elite endurance athletes. Scand J Med Sci Sports: Sidelmann JJ; 2014. Melin A, Tornberg AB, Skouby S, Moller SS, Sundgot-Borgen J. Faber J. Aziz M, Sjodin A. Energy availability and the female athlete triad in elite endurance athletes. Scand J Med Sci Sports: Sidelmann JJ; 2014.
8.
go back to reference Stuhldreher N, Konnopka A, Wild B, Herzog W, Zipfel S, Löwe B, König H-H. Cost-of-illness studies and cost-effectiveness analyses in eating disorders: a systematic review. Int J Eat Disord. 2012;45:476–91.CrossRefPubMed Stuhldreher N, Konnopka A, Wild B, Herzog W, Zipfel S, Löwe B, König H-H. Cost-of-illness studies and cost-effectiveness analyses in eating disorders: a systematic review. Int J Eat Disord. 2012;45:476–91.CrossRefPubMed
9.
go back to reference Simon J, Schmidt U, Pilling S. The health service use and cost of eating disorders. Psychol Med. 2005;35:1543–51.CrossRefPubMed Simon J, Schmidt U, Pilling S. The health service use and cost of eating disorders. Psychol Med. 2005;35:1543–51.CrossRefPubMed
10.
go back to reference Ágh T, Covács G, Supina D, Pawaskar M, Herman BK, Voko Z, Sheehan DV. A systematic review of the health-related quality of life and economic burdens of anorexia nervosa, bulimia nervosa, and binge eating disorder. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity. 2016:1–12. Ágh T, Covács G, Supina D, Pawaskar M, Herman BK, Voko Z, Sheehan DV. A systematic review of the health-related quality of life and economic burdens of anorexia nervosa, bulimia nervosa, and binge eating disorder. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity. 2016:1–12.
11.
go back to reference Rosenvinge JH, Klusmeier AK. Treatment for eating disorders from a patient satisfaction perspective: a Norwegian replication of a British study. Eur Eat Disord Rev. 2000;8:293–300.CrossRef Rosenvinge JH, Klusmeier AK. Treatment for eating disorders from a patient satisfaction perspective: a Norwegian replication of a British study. Eur Eat Disord Rev. 2000;8:293–300.CrossRef
12.
go back to reference Hoek HW, van Hoeken D. Review of the prevalence and incidence of eating disorders. Int J Eat Disord. 2003;34:383–96.CrossRefPubMed Hoek HW, van Hoeken D. Review of the prevalence and incidence of eating disorders. Int J Eat Disord. 2003;34:383–96.CrossRefPubMed
13.
go back to reference Reichborn-Kjennerud T, Bulik CM, Sullivan PF, Tambs K, Harris JR. Psychiatric and medical symptoms in binge eating in the absence of compensatory behaviors. Obes Res. 2004;12:1445–54.CrossRefPubMed Reichborn-Kjennerud T, Bulik CM, Sullivan PF, Tambs K, Harris JR. Psychiatric and medical symptoms in binge eating in the absence of compensatory behaviors. Obes Res. 2004;12:1445–54.CrossRefPubMed
14.
go back to reference Wentz E, Gillberg C, Gillberg IC, Råstam M. Ten year follow up of adolescent onset anorexia nervosa: psychiatric disorders and overall functioning scales. J Child Psychol Psychiatry. 2001;42:613–22.CrossRefPubMed Wentz E, Gillberg C, Gillberg IC, Råstam M. Ten year follow up of adolescent onset anorexia nervosa: psychiatric disorders and overall functioning scales. J Child Psychol Psychiatry. 2001;42:613–22.CrossRefPubMed
15.
go back to reference Keski-Rahkonen A, Hoek HW, Susser ES, Linna MS, Sihvola E, Raevuori A, Bulik CM, Kaprio J, Rissanen A. Epidemiology and course of anorexia nervosa in the community. Am J Psychiatry. 2007;164:1259–65.CrossRefPubMed Keski-Rahkonen A, Hoek HW, Susser ES, Linna MS, Sihvola E, Raevuori A, Bulik CM, Kaprio J, Rissanen A. Epidemiology and course of anorexia nervosa in the community. Am J Psychiatry. 2007;164:1259–65.CrossRefPubMed
16.
go back to reference Rosenvinge JH, Pettersen G. Epidemiology of eating disorders part II: an update with a special reference to the DSM-5. Adv Eat Disord Theory Res Pract. 2015;3:198–220.CrossRef Rosenvinge JH, Pettersen G. Epidemiology of eating disorders part II: an update with a special reference to the DSM-5. Adv Eat Disord Theory Res Pract. 2015;3:198–220.CrossRef
17.
go back to reference Mahon J. Dropping out from psychological treatment for eating disorders: what are the issues? Eur Eat Disord Rev. 2000;8:198–216.CrossRef Mahon J. Dropping out from psychological treatment for eating disorders: what are the issues? Eur Eat Disord Rev. 2000;8:198–216.CrossRef
18.
go back to reference Wilson GT, Grilo CM, Vitousek KM. Psychological treatment of eating disorders. Am Psychol. 2007;62:199.CrossRefPubMed Wilson GT, Grilo CM, Vitousek KM. Psychological treatment of eating disorders. Am Psychol. 2007;62:199.CrossRefPubMed
19.
go back to reference Waller G. A trans-transdiagnostic model of the eating disorders: a new way to open the egg? Eur Eat Disord Rev. 2008;16:165–72.CrossRefPubMed Waller G. A trans-transdiagnostic model of the eating disorders: a new way to open the egg? Eur Eat Disord Rev. 2008;16:165–72.CrossRefPubMed
20.
go back to reference Hay P. A systematic review of evidence for psychological treatments in eating disorders: 2005-2012. Int J Eat Disord. 2013;46:462–9.CrossRefPubMed Hay P. A systematic review of evidence for psychological treatments in eating disorders: 2005-2012. Int J Eat Disord. 2013;46:462–9.CrossRefPubMed
21.
go back to reference Spielmans GI, Benish SG, Marin C, Bowman WM, Menster M, Wheeler AJ. Specificity of psychological treatments for bulimia nervosa and binge eating disorder? A meta-analysis of direct comparisons. Clin Psychol Rev. 2013;33:460–9.CrossRefPubMed Spielmans GI, Benish SG, Marin C, Bowman WM, Menster M, Wheeler AJ. Specificity of psychological treatments for bulimia nervosa and binge eating disorder? A meta-analysis of direct comparisons. Clin Psychol Rev. 2013;33:460–9.CrossRefPubMed
23.
go back to reference Groff SE. Is enhanced cognitive behavioral therapy an effective intervention in eating disorders? A review. J Evid Inf Soc Work. 2015:1–17. Groff SE. Is enhanced cognitive behavioral therapy an effective intervention in eating disorders? A review. J Evid Inf Soc Work. 2015:1–17.
24.
go back to reference Fairburn CG, Cooper Z, Shafran R. Cognitive behaviour therapy for eating disorders: a "transdiagnostic" theory and treatment. Behav Res Ther. 2003;41:509–28.CrossRefPubMed Fairburn CG, Cooper Z, Shafran R. Cognitive behaviour therapy for eating disorders: a "transdiagnostic" theory and treatment. Behav Res Ther. 2003;41:509–28.CrossRefPubMed
26.
go back to reference Pinna F, Sanna L, Carpiniello B. Alexithymia in eating disorders: therapeutic implications. Psychol Res Behav Manag. 2015;8:1.PubMed Pinna F, Sanna L, Carpiniello B. Alexithymia in eating disorders: therapeutic implications. Psychol Res Behav Manag. 2015;8:1.PubMed
27.
go back to reference Bratland-Sanda S, Martinsen EW, Rosenvinge JH, Ro O, Hoffart A, Sundgot-Borgen J. Exercise dependence score in patients with longstanding eating disorders and controls: the importance of affect regulation and physical activity intensity. Eur Eat Disord Rev. 2011;19:249–55.CrossRefPubMed Bratland-Sanda S, Martinsen EW, Rosenvinge JH, Ro O, Hoffart A, Sundgot-Borgen J. Exercise dependence score in patients with longstanding eating disorders and controls: the importance of affect regulation and physical activity intensity. Eur Eat Disord Rev. 2011;19:249–55.CrossRefPubMed
28.
go back to reference Bratland-Sanda S, Rosenvinge JH, Vrabel KA, Norring C, Sundgot-Borgen J, Ro O, Martinsen EW. Physical activity in treatment units for eating disorders: clinical practice and attitudes. Eat Weight Disord. 2009;14:e106–12.CrossRefPubMed Bratland-Sanda S, Rosenvinge JH, Vrabel KA, Norring C, Sundgot-Borgen J, Ro O, Martinsen EW. Physical activity in treatment units for eating disorders: clinical practice and attitudes. Eat Weight Disord. 2009;14:e106–12.CrossRefPubMed
29.
go back to reference Sundgot-Borgen J, Rosenvinge JH, Bahr R, Schneider LS. The effect of exercise, cognitive therapy, and nutritional counseling in treating bulimia nervosa. Med Sci Sports Exerc. 2002;34:190–5.CrossRefPubMed Sundgot-Borgen J, Rosenvinge JH, Bahr R, Schneider LS. The effect of exercise, cognitive therapy, and nutritional counseling in treating bulimia nervosa. Med Sci Sports Exerc. 2002;34:190–5.CrossRefPubMed
30.
go back to reference Laessle RG, Beumont PJ, Butow P, Lennerts W, O'Connor M, Pirke KM, Touyz SW, Waadt S. A comparison of nutritional management with stress management in the treatment of bulimia nervosa. Br J Psychiatry. 1991;159:250–61.CrossRefPubMed Laessle RG, Beumont PJ, Butow P, Lennerts W, O'Connor M, Pirke KM, Touyz SW, Waadt S. A comparison of nutritional management with stress management in the treatment of bulimia nervosa. Br J Psychiatry. 1991;159:250–61.CrossRefPubMed
31.
go back to reference Brauhardt A. De ZM, Hilbert a. The therapeutic process in psychological treatments for eating disorders: a systematic review. Int J Eat Disord. 2014;47:565–84.CrossRefPubMed Brauhardt A. De ZM, Hilbert a. The therapeutic process in psychological treatments for eating disorders: a systematic review. Int J Eat Disord. 2014;47:565–84.CrossRefPubMed
32.
go back to reference Wampold BE. How important are the common factors in psychotherapy? An update World Psychiatry. 2015;14:270–7.CrossRefPubMed Wampold BE. How important are the common factors in psychotherapy? An update World Psychiatry. 2015;14:270–7.CrossRefPubMed
33.
go back to reference Horvath AO, Del Re AC, Flückiger C, Symonds D. Alliance in individual psychotherapy. Psychotherapy. 2011;48:9.CrossRefPubMed Horvath AO, Del Re AC, Flückiger C, Symonds D. Alliance in individual psychotherapy. Psychotherapy. 2011;48:9.CrossRefPubMed
34.
go back to reference Stiles-Shields C, Bamford BH, Touyz S, Le Grange D, Hay P, Lacey H. Predictors of therapeutic alliance in two treatments for adults with severe and enduring anorexia nervosa. J Eat Disord. 2016;4:1.CrossRef Stiles-Shields C, Bamford BH, Touyz S, Le Grange D, Hay P, Lacey H. Predictors of therapeutic alliance in two treatments for adults with severe and enduring anorexia nervosa. J Eat Disord. 2016;4:1.CrossRef
35.
go back to reference Zaitsoff S, Pullmer R, Cyr M, Aime H. The role of the therapeutic alliance in eating disorder treatment outcomes: a systematic review. Eat Disord. 2015;23:99–114.CrossRefPubMed Zaitsoff S, Pullmer R, Cyr M, Aime H. The role of the therapeutic alliance in eating disorder treatment outcomes: a systematic review. Eat Disord. 2015;23:99–114.CrossRefPubMed
36.
go back to reference Tasca GA, Balfour L, Ritchie K, Bissada H. Developmental changes in group climate in two types of group therapy for binge-eating disorder: a growth curve analysis. Psychother Res. 2006;16:499–514.CrossRef Tasca GA, Balfour L, Ritchie K, Bissada H. Developmental changes in group climate in two types of group therapy for binge-eating disorder: a growth curve analysis. Psychother Res. 2006;16:499–514.CrossRef
37.
go back to reference Linardon J, Brennan L, de la Piedad Garcia X. Rapid response to eating disorder treatment: a systematic review and meta-analysis. Int J Eat Disord. 2016;49(10):905–19. Linardon J, Brennan L, de la Piedad Garcia X. Rapid response to eating disorder treatment: a systematic review and meta-analysis. Int J Eat Disord. 2016;49(10):905–19.
38.
go back to reference MacDonald DE, Trottier K, McFarlane T, Olmsted MP. Empirically defining rapid response to intensive treatment to maximize prognostic utility for bulimia nervosa and purging disorder. Behav Res Ther. 2015;68:48–53.CrossRefPubMed MacDonald DE, Trottier K, McFarlane T, Olmsted MP. Empirically defining rapid response to intensive treatment to maximize prognostic utility for bulimia nervosa and purging disorder. Behav Res Ther. 2015;68:48–53.CrossRefPubMed
39.
go back to reference Thompson-Brenner H, Shingleton RM, Sauer-Zavala S, Richards LK, Pratt EM. Multiple measures of rapid response as predictors of remission in cognitive behavior therapy for bulimia nervosa. Behav Res Ther. 2015;64:9–14.CrossRefPubMed Thompson-Brenner H, Shingleton RM, Sauer-Zavala S, Richards LK, Pratt EM. Multiple measures of rapid response as predictors of remission in cognitive behavior therapy for bulimia nervosa. Behav Res Ther. 2015;64:9–14.CrossRefPubMed
40.
go back to reference Rector NA, Zuroff DC, Segal ZV. Cognitive change and the therapeutic alliance: the role of technical and nontechnical factors in cognitive therapy. Psychotherapy. 1999;36:320.CrossRef Rector NA, Zuroff DC, Segal ZV. Cognitive change and the therapeutic alliance: the role of technical and nontechnical factors in cognitive therapy. Psychotherapy. 1999;36:320.CrossRef
41.
go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5), 5.th edn. American Psychiatric Pub; 2013. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5), 5.th edn. American Psychiatric Pub; 2013.
42.
go back to reference Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC. The MINI-international neuropsychiatric interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59:22–33.PubMed Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Hergueta T, Baker R, Dunbar GC. The MINI-international neuropsychiatric interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59:22–33.PubMed
43.
go back to reference Luce KH, Crowther JH. The reliability of the eating disorder examination- selfreport questionnaire version (EDE-Q). Int J Eat Disord. 1999;25:349–51.CrossRefPubMed Luce KH, Crowther JH. The reliability of the eating disorder examination- selfreport questionnaire version (EDE-Q). Int J Eat Disord. 1999;25:349–51.CrossRefPubMed
44.
go back to reference Mond JM, Hay PJ, Rodgers B, Owen C, Beumont PJ. Validity of the eating disorder examination questionnaire (EDE-Q) in screening for eating disorders in community samples. Behav Res Ther. 2004;42:551–67.CrossRefPubMed Mond JM, Hay PJ, Rodgers B, Owen C, Beumont PJ. Validity of the eating disorder examination questionnaire (EDE-Q) in screening for eating disorders in community samples. Behav Res Ther. 2004;42:551–67.CrossRefPubMed
45.
go back to reference Fairburn CG, Cooper Z, Doll HA, O'Connor ME, Bohn K, Hawker DM, Wales JA, Palmer RL. Transdiagnostic cognitive-behavioral therapy for patients with eating disorders: a two-site trial with 60-week follow-up. Am J Psychiatr. 2009;166:311–9.CrossRefPubMed Fairburn CG, Cooper Z, Doll HA, O'Connor ME, Bohn K, Hawker DM, Wales JA, Palmer RL. Transdiagnostic cognitive-behavioral therapy for patients with eating disorders: a two-site trial with 60-week follow-up. Am J Psychiatr. 2009;166:311–9.CrossRefPubMed
46.
go back to reference Fairburn CG, Bailey-Straebler S, Basden S, Doll HA, Jones R, Murphy R, O'Connor ME, Cooper Z. A transdiagnostic comparison of enhanced cognitive behaviour therapy (CBT-E) and interpersonal psychotherapy in the treatment of eating disorders. Behav Res Ther. 2015;70:64–71.CrossRefPubMedPubMedCentral Fairburn CG, Bailey-Straebler S, Basden S, Doll HA, Jones R, Murphy R, O'Connor ME, Cooper Z. A transdiagnostic comparison of enhanced cognitive behaviour therapy (CBT-E) and interpersonal psychotherapy in the treatment of eating disorders. Behav Res Ther. 2015;70:64–71.CrossRefPubMedPubMedCentral
47.
go back to reference Cook B, Wonderlich SA, Mitchell J, Thompson R, Sherman R, McCallum K. Exercise in eating disorders treatment: systematic review and proposal of guidelines. Med Sci Sports Exerc. 2016;48:1408–14.CrossRefPubMed Cook B, Wonderlich SA, Mitchell J, Thompson R, Sherman R, McCallum K. Exercise in eating disorders treatment: systematic review and proposal of guidelines. Med Sci Sports Exerc. 2016;48:1408–14.CrossRefPubMed
49.
go back to reference Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43:1334–59.CrossRefPubMed Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, Nieman DC, Swain DP. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc. 2011;43:1334–59.CrossRefPubMed
51.
go back to reference Loveless MS, Ihm JM. Resistance exercise: how much is enough? Curr Sports Med Rep. 2015;14:221–6.CrossRefPubMed Loveless MS, Ihm JM. Resistance exercise: how much is enough? Curr Sports Med Rep. 2015;14:221–6.CrossRefPubMed
52.
go back to reference Prabhakaran B, Dowling EA, Branch JD, Swain DP, Leutholtz BC. Effect of 14 weeks of resistance training on lipid profile and body fat percentage in premenopausal women. Br J Sports Med. 1999;33:190–5.CrossRefPubMedPubMedCentral Prabhakaran B, Dowling EA, Branch JD, Swain DP, Leutholtz BC. Effect of 14 weeks of resistance training on lipid profile and body fat percentage in premenopausal women. Br J Sports Med. 1999;33:190–5.CrossRefPubMedPubMedCentral
53.
go back to reference Martyn-St James M, Carroll S. Effects of different impact exercise modalities on bone mineral density in premenopausal women: a meta-analysis. J Bone Miner Metab. 2010;28:251–67.CrossRefPubMed Martyn-St James M, Carroll S. Effects of different impact exercise modalities on bone mineral density in premenopausal women: a meta-analysis. J Bone Miner Metab. 2010;28:251–67.CrossRefPubMed
54.
55.
go back to reference Votruba SB, Horvitz MA, Schoeller DA. The role of exercise in the treatment of obesity. Nutrition. 2000;16:179–88.CrossRefPubMed Votruba SB, Horvitz MA, Schoeller DA. The role of exercise in the treatment of obesity. Nutrition. 2000;16:179–88.CrossRefPubMed
56.
go back to reference Chmelo EA, Hall EE, Miller PC, Sanders KN. Mirrors and resistance exercise, do they influence affective responses? J Health Psychol. 2009;14:1067–74.CrossRefPubMed Chmelo EA, Hall EE, Miller PC, Sanders KN. Mirrors and resistance exercise, do they influence affective responses? J Health Psychol. 2009;14:1067–74.CrossRefPubMed
57.
go back to reference Moore JB, Mitchell NG, Bibeau WS, Bartholomew JB. Effects of a 12-week resistance exercise program on physical self-perceptions in college students. Res Q Exerc Sport. 2011;82:291–301.CrossRefPubMed Moore JB, Mitchell NG, Bibeau WS, Bartholomew JB. Effects of a 12-week resistance exercise program on physical self-perceptions in college students. Res Q Exerc Sport. 2011;82:291–301.CrossRefPubMed
58.
go back to reference Taspinar B, Aslan UB, Agbuga B, Taspinar F. A comparison of the effects of hatha yoga and resistance exercise on mental health and well-being in sedentary adults: a pilot study. Complementary therapies in medicine. 2014;22:433–40.CrossRefPubMed Taspinar B, Aslan UB, Agbuga B, Taspinar F. A comparison of the effects of hatha yoga and resistance exercise on mental health and well-being in sedentary adults: a pilot study. Complementary therapies in medicine. 2014;22:433–40.CrossRefPubMed
59.
go back to reference Hale BS, Raglin JS. State anxiety responses to acute resistance training and step aerobic exercise across 8-weeks of training. J Sports Med Phys Fitness. 2002;42:108.PubMed Hale BS, Raglin JS. State anxiety responses to acute resistance training and step aerobic exercise across 8-weeks of training. J Sports Med Phys Fitness. 2002;42:108.PubMed
60.
go back to reference Focht BC. Pre-exercise anxiety and the anxiolytic responses to acute bouts of self-selected and prescribed intensity resistance exercise. J Sports Med Phys Fitness. 2002;42:217.PubMed Focht BC. Pre-exercise anxiety and the anxiolytic responses to acute bouts of self-selected and prescribed intensity resistance exercise. J Sports Med Phys Fitness. 2002;42:217.PubMed
61.
go back to reference Bacon AP, Carter RE, Ogle EA, Joyner MJ. VO 2 max trainability and high intensity interval training in humans: a meta-analysis. PLoS One. 2013;8:e73182.CrossRefPubMedPubMedCentral Bacon AP, Carter RE, Ogle EA, Joyner MJ. VO 2 max trainability and high intensity interval training in humans: a meta-analysis. PLoS One. 2013;8:e73182.CrossRefPubMedPubMedCentral
62.
go back to reference Sloth M, Sloth D, Overgaard K, Dalgas U. Effects of sprint interval training on VO2max and aerobic exercise performance: a systematic review and meta-analysis. Scand J Med Sci Sports. 2013;23:e341–52.CrossRefPubMed Sloth M, Sloth D, Overgaard K, Dalgas U. Effects of sprint interval training on VO2max and aerobic exercise performance: a systematic review and meta-analysis. Scand J Med Sci Sports. 2013;23:e341–52.CrossRefPubMed
63.
go back to reference Fisher G, Brown AW, Brown MMB, Alcorn A, Noles C, Winwood L, Resuehr H, George B, Jeansonne MM, Allison DB. High intensity interval-vs moderate intensity-training for improving Cardiometabolic health in overweight or obese males: a randomized controlled trial. PLoS One. 2015;10:e0138853.CrossRefPubMedPubMedCentral Fisher G, Brown AW, Brown MMB, Alcorn A, Noles C, Winwood L, Resuehr H, George B, Jeansonne MM, Allison DB. High intensity interval-vs moderate intensity-training for improving Cardiometabolic health in overweight or obese males: a randomized controlled trial. PLoS One. 2015;10:e0138853.CrossRefPubMedPubMedCentral
64.
go back to reference Hazell TJ, Hamilton CD, Olver TD, Lemon PW. Running sprint interval training induces fat loss in women. Appl Physiol Nutr Metab. 2014;39:944–50.CrossRefPubMed Hazell TJ, Hamilton CD, Olver TD, Lemon PW. Running sprint interval training induces fat loss in women. Appl Physiol Nutr Metab. 2014;39:944–50.CrossRefPubMed
65.
go back to reference Kraemer WJ, Adams K, Cafarelli E, Dudley GA, Dooly C, Feigenbaum MS, Fleck SJ, Franklin B, Fry AC, Hoffman JR. American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med Sci Sports Exerc. 2002;34:364–80.CrossRefPubMed Kraemer WJ, Adams K, Cafarelli E, Dudley GA, Dooly C, Feigenbaum MS, Fleck SJ, Franklin B, Fry AC, Hoffman JR. American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. Med Sci Sports Exerc. 2002;34:364–80.CrossRefPubMed
66.
go back to reference Barber JP, Liese BS, Abrams MJ. Development of the cognitive therapy adherence and competence scale. Psychother Res. 2003;13:205–21.CrossRef Barber JP, Liese BS, Abrams MJ. Development of the cognitive therapy adherence and competence scale. Psychother Res. 2003;13:205–21.CrossRef
67.
go back to reference Clarsen B, Roensen O, Myklebust G, Floerenes TW, Bahr R. The Oslo Sports Trauma Research Center questionnaire on health problems: a new approach to prospective monitoring of illness and injury in elite athletes. Br J Sports Med. 2013;bjsports-2012. Clarsen B, Roensen O, Myklebust G, Floerenes TW, Bahr R. The Oslo Sports Trauma Research Center questionnaire on health problems: a new approach to prospective monitoring of illness and injury in elite athletes. Br J Sports Med. 2013;bjsports-2012.
68.
go back to reference Ackland TR, Lohman TG, Sundgot-Borgen J, Maughan RJ, Meyer NL, Stewart AD, Muller W. Current status of body composition assessment in sport: review and position statement on behalf of the ad hoc research working group on body composition health and performance, under the auspices of the I.O.C. Medical commission. Sports Med. 2012;42:227–49.CrossRefPubMed Ackland TR, Lohman TG, Sundgot-Borgen J, Maughan RJ, Meyer NL, Stewart AD, Muller W. Current status of body composition assessment in sport: review and position statement on behalf of the ad hoc research working group on body composition health and performance, under the auspices of the I.O.C. Medical commission. Sports Med. 2012;42:227–49.CrossRefPubMed
69.
go back to reference Maud PJ, Foster C. Physiological assessment of human fitness. 2nd ed. Champaign: Human Kinetics; 2006. Maud PJ, Foster C. Physiological assessment of human fitness. 2nd ed. Champaign: Human Kinetics; 2006.
70.
go back to reference Lupash E. ACSM’s guidelines for exercise testing and prescription. 9th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health; 2014. Lupash E. ACSM’s guidelines for exercise testing and prescription. 9th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health; 2014.
71.
go back to reference Ried-Larsen M, Brønd JC, Brage S, Hansen BH, Grydeland M, Andersen LB, Møller NC. Mechanical and free living comparisons of four generations of the Actigraph activity monitor. Int J Behav Nutr Phys Act. 2012;9:1.CrossRef Ried-Larsen M, Brønd JC, Brage S, Hansen BH, Grydeland M, Andersen LB, Møller NC. Mechanical and free living comparisons of four generations of the Actigraph activity monitor. Int J Behav Nutr Phys Act. 2012;9:1.CrossRef
72.
go back to reference Edvardsen E. Hansen BrH, Holme IM, Dyrstad SM, Anderssen SA. Reference values for cardiorespiratory response and fitness on the treadmill in a 20-to 85-year-old population. CHEST Journal. 2013;144:241–8.CrossRef Edvardsen E. Hansen BrH, Holme IM, Dyrstad SM, Anderssen SA. Reference values for cardiorespiratory response and fitness on the treadmill in a 20-to 85-year-old population. CHEST Journal. 2013;144:241–8.CrossRef
73.
74.
go back to reference Balke B, Ware RW. An experimental study of physical fitness of air force personnel. U S Armed Forces Med J. 1959;10:675–88.PubMed Balke B, Ware RW. An experimental study of physical fitness of air force personnel. U S Armed Forces Med J. 1959;10:675–88.PubMed
75.
go back to reference Nana A, Slater GJ, Stewart AD, Burke LM. Methodology review: using dual-energy X-ray absorptiometry (DXA) for the assessment of body composition in athletes and active people. Int J Sport Nutr Exerc Metab. 2014; Nana A, Slater GJ, Stewart AD, Burke LM. Methodology review: using dual-energy X-ray absorptiometry (DXA) for the assessment of body composition in athletes and active people. Int J Sport Nutr Exerc Metab. 2014;
76.
go back to reference Hausenblas HA, Downs DS. How much is too much? The development and validation of the exercise dependence scale. Psychol Health. 2002;17:387–404.CrossRef Hausenblas HA, Downs DS. How much is too much? The development and validation of the exercise dependence scale. Psychol Health. 2002;17:387–404.CrossRef
77.
go back to reference Taranis L, Touyz S, Meyer C. Disordered eating and exercise: development and preliminary validation of the compulsive exercise test (CET). Eur Eat Disord Rev. 2011;19:256–68.CrossRefPubMed Taranis L, Touyz S, Meyer C. Disordered eating and exercise: development and preliminary validation of the compulsive exercise test (CET). Eur Eat Disord Rev. 2011;19:256–68.CrossRefPubMed
78.
go back to reference Clinton D. Expectations and experiences of treatment in eating disorders. Eat Disord. 2001;9:361–71.CrossRefPubMed Clinton D. Expectations and experiences of treatment in eating disorders. Eat Disord. 2001;9:361–71.CrossRefPubMed
79.
go back to reference Pettersen G, Thune-Larsen KB, Wynn R, Rosenvinge JH. Eating disorders: challenges in the later phases of the recovery process. Scand J Caring Sci. 2013;27:92–8.CrossRefPubMed Pettersen G, Thune-Larsen KB, Wynn R, Rosenvinge JH. Eating disorders: challenges in the later phases of the recovery process. Scand J Caring Sci. 2013;27:92–8.CrossRefPubMed
80.
go back to reference Pettersen G, Rosenvinge JH, Wynn R. Eating disorders and psychoeducation--patients' experiences of healing processes. Scand J Caring Sci. 2011;25:12–8.CrossRefPubMed Pettersen G, Rosenvinge JH, Wynn R. Eating disorders and psychoeducation--patients' experiences of healing processes. Scand J Caring Sci. 2011;25:12–8.CrossRefPubMed
81.
go back to reference Malterud K. Systematic text condensation: a strategy for qualitative analysis. Scand J Publ Health. 2012;40:795–805.CrossRef Malterud K. Systematic text condensation: a strategy for qualitative analysis. Scand J Publ Health. 2012;40:795–805.CrossRef
82.
go back to reference Horvath AO, Greenberg LS. Development and validation of the working alliance inventory. J Couns Psychol. 1989;36:223.CrossRef Horvath AO, Greenberg LS. Development and validation of the working alliance inventory. J Couns Psychol. 1989;36:223.CrossRef
83.
go back to reference Lese KP, MacNair-Semands RR. The therapeutic factors inventory: development of a scale. Group. 2000;24:303–17.CrossRef Lese KP, MacNair-Semands RR. The therapeutic factors inventory: development of a scale. Group. 2000;24:303–17.CrossRef
84.
go back to reference Rush AJ. Blacker D. Handbook of psychiatric measures: American Psychiatric Press Inc; 2008. Rush AJ. Blacker D. Handbook of psychiatric measures: American Psychiatric Press Inc; 2008.
85.
go back to reference MacNair-Semands RR, Ogrodniczuk JS, Joyce AS. Structure and initial validation of a short form of the therapeutic factors inventory. Int J Group Psychother. 2010;60:245–81.CrossRefPubMed MacNair-Semands RR, Ogrodniczuk JS, Joyce AS. Structure and initial validation of a short form of the therapeutic factors inventory. Int J Group Psychother. 2010;60:245–81.CrossRefPubMed
86.
go back to reference Rosenvinge JH, Pettersen G. Towards a comprehensive model of recovery, Relevant topics in Eating Disorders. In: Mental and Behavioural Disorders and Diseases of the Nervous System. Edited by Lobera IJ. InTech; 2012. p. Rosenvinge JH, Pettersen G. Towards a comprehensive model of recovery, Relevant topics in Eating Disorders. In: Mental and Behavioural Disorders and Diseases of the Nervous System. Edited by Lobera IJ. InTech; 2012. p.
87.
go back to reference Paulson-Karlsson G, Nevonen L, Engström I. Anorexia nervosa: treatment satisfaction. J Fam Ther. 2006;28:293–306.CrossRef Paulson-Karlsson G, Nevonen L, Engström I. Anorexia nervosa: treatment satisfaction. J Fam Ther. 2006;28:293–306.CrossRef
88.
go back to reference Shafran R, Clark DM, Fairburn CG, Arntz A, Barlow DH, Ehlers A, Freeston M, Garety PA, Hollon SD, Ost LG. Mind the gap: improving the dissemination of CBT. Behav Res Ther. 2009;47:902–9.CrossRefPubMed Shafran R, Clark DM, Fairburn CG, Arntz A, Barlow DH, Ehlers A, Freeston M, Garety PA, Hollon SD, Ost LG. Mind the gap: improving the dissemination of CBT. Behav Res Ther. 2009;47:902–9.CrossRefPubMed
89.
go back to reference Godart NT, Flament MF, Perdereau F, Jeammet P. Comorbidity between eating disorders and anxiety disorders: a review. Int J Eat Disord. 2002;32:253–70.CrossRefPubMed Godart NT, Flament MF, Perdereau F, Jeammet P. Comorbidity between eating disorders and anxiety disorders: a review. Int J Eat Disord. 2002;32:253–70.CrossRefPubMed
90.
go back to reference Welch E, Jangmo A, Thornton LM, Norring C, von Hausswolff-Juhlin Y, Herman BK, Pawaskar M, Larsson H, Bulik CM. Treatment-seeking patients with binge-eating disorder in the Swedish national registers: clinical course and psychiatric comorbidity. BMC psychiatry. 2016;16:1.CrossRef Welch E, Jangmo A, Thornton LM, Norring C, von Hausswolff-Juhlin Y, Herman BK, Pawaskar M, Larsson H, Bulik CM. Treatment-seeking patients with binge-eating disorder in the Swedish national registers: clinical course and psychiatric comorbidity. BMC psychiatry. 2016;16:1.CrossRef
91.
go back to reference Rosenvinge JH, Martinussen M, Østensen E. The comorbidity of eating disorders and personality disorders: a metaanalytic review of studies published between 1983 and 1998. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity. 2000;5:52–61.CrossRef Rosenvinge JH, Martinussen M, Østensen E. The comorbidity of eating disorders and personality disorders: a metaanalytic review of studies published between 1983 and 1998. Eating and Weight Disorders-Studies on Anorexia, Bulimia and Obesity. 2000;5:52–61.CrossRef
92.
go back to reference Friborg O, Martinussen M, Kaiser S, Øvergård KT, Martinsen EW, Schmierer P, Rosenvinge JH. Personality disorders in eating disorder not otherwise specified and binge eating disorder: a meta-analysis of comorbidity studies. J Nerv Ment Dis. 2014;202:119–25.CrossRefPubMed Friborg O, Martinussen M, Kaiser S, Øvergård KT, Martinsen EW, Schmierer P, Rosenvinge JH. Personality disorders in eating disorder not otherwise specified and binge eating disorder: a meta-analysis of comorbidity studies. J Nerv Ment Dis. 2014;202:119–25.CrossRefPubMed
93.
go back to reference Swanson SA, Crow SJ, Le Grange D, Swendsen J, Merikangas KR. Prevalence and correlates of eating disorders in adolescents: results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry. 2011;68:714–23.CrossRefPubMed Swanson SA, Crow SJ, Le Grange D, Swendsen J, Merikangas KR. Prevalence and correlates of eating disorders in adolescents: results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry. 2011;68:714–23.CrossRefPubMed
94.
go back to reference Carter O, Pannekoek L, Fursland A, Allen KL, Lampard AM, Byrne SM. Increased wait-list time predicts dropout from outpatient enhanced cognitive behaviour therapy (CBT-E) for eating disorders. Behav Res Ther. 2012;50:487–92.CrossRefPubMed Carter O, Pannekoek L, Fursland A, Allen KL, Lampard AM, Byrne SM. Increased wait-list time predicts dropout from outpatient enhanced cognitive behaviour therapy (CBT-E) for eating disorders. Behav Res Ther. 2012;50:487–92.CrossRefPubMed
95.
go back to reference Fairburn CG. Cognitive behavior therapy and eating disorders. New York: The Guilford Press; 2008. Fairburn CG. Cognitive behavior therapy and eating disorders. New York: The Guilford Press; 2008.
96.
go back to reference Freitas SR, Lopes CS, Appolinario JC, Coutinho W. The assessment of binge eating disorder in obese women: a comparison of the binge eating scale with the structured clinical interview for the DSM-IV. Eat Behav. 2006;7:282–9.CrossRefPubMed Freitas SR, Lopes CS, Appolinario JC, Coutinho W. The assessment of binge eating disorder in obese women: a comparison of the binge eating scale with the structured clinical interview for the DSM-IV. Eat Behav. 2006;7:282–9.CrossRefPubMed
97.
go back to reference Beck, A. T. and Steer, R. A.Beck anxiety inventory manual Beck, A. T. and Steer, R. A.Beck anxiety inventory manual
98.
go back to reference Garner DM. Eating disorder inventory-3 (EDI-3). Professional manual Odessa. Psychological Assessment Resources: FL; 2004. Garner DM. Eating disorder inventory-3 (EDI-3). Professional manual Odessa. Psychological Assessment Resources: FL; 2004.
99.
go back to reference Stunkard AJ, Messick S. The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J Psychosom Res. 1985;29:71–83.CrossRefPubMed Stunkard AJ, Messick S. The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J Psychosom Res. 1985;29:71–83.CrossRefPubMed
100.
go back to reference Rosenvinge JH, Perry JA, Bjørgum L, Holte A. A new instrument measuring bulimia nervosa and disturbed eating patterns: development and validation of a 5-item scale. Eur Eat Disord Rev. 2001;9:123–32.CrossRef Rosenvinge JH, Perry JA, Bjørgum L, Holte A. A new instrument measuring bulimia nervosa and disturbed eating patterns: development and validation of a 5-item scale. Eur Eat Disord Rev. 2001;9:123–32.CrossRef
101.
go back to reference Beck AT, Steer RA, Brown GK. Manual for the beck depression inventory-II. San Antonio, TX: Psychological Corporation. 1996;1:82. Beck AT, Steer RA, Brown GK. Manual for the beck depression inventory-II. San Antonio, TX: Psychological Corporation. 1996;1:82.
102.
go back to reference Diener E. Assessing subjective well-being: progress and opportunities. Soc Indic Res. 1994;31:103–57.CrossRef Diener E. Assessing subjective well-being: progress and opportunities. Soc Indic Res. 1994;31:103–57.CrossRef
103.
go back to reference Cantril H. The pattern of human concerns. New Brunswick: New Brunswick, N.J., Rutgers University Press; 1965. Cantril H. The pattern of human concerns. New Brunswick: New Brunswick, N.J., Rutgers University Press; 1965.
104.
go back to reference Turner H, Bryant-Waugh R, Peveler R, Bucks RS. A psychometric evaluation of an English version of the Utrecht Coping List. Eur Eat Disord Rev. 2012;20(4):339–42. Turner H, Bryant-Waugh R, Peveler R, Bucks RS. A psychometric evaluation of an English version of the Utrecht Coping List. Eur Eat Disord Rev. 2012;20(4):339–42.
105.
go back to reference Friborg O, Hjemdal O, Rosenvinge JH, Martinussen M. A new rating scale for adult resilience: what are the central protective resources behind healthy adjustment? Int J Methods Psychiatr Res. 2003;12:65–76.CrossRefPubMed Friborg O, Hjemdal O, Rosenvinge JH, Martinussen M. A new rating scale for adult resilience: what are the central protective resources behind healthy adjustment? Int J Methods Psychiatr Res. 2003;12:65–76.CrossRefPubMed
106.
go back to reference Miller SD, Duncan BL, Brown J, Sparks JA, Claud DA. The outcome rating scale: a preliminary study of the reliability, validity, and feasibility of a brief visual analog measure. Journal of brief Therapy. 2003;2:91–100. Miller SD, Duncan BL, Brown J, Sparks JA, Claud DA. The outcome rating scale: a preliminary study of the reliability, validity, and feasibility of a brief visual analog measure. Journal of brief Therapy. 2003;2:91–100.
Metadata
Title
The PED-t trial protocol: The effect of physical exercise –and dietary therapy compared with cognitive behavior therapy in treatment of bulimia nervosa and binge eating disorder
Authors
Therese Fostervold Mathisen
Jan H. Rosenvinge
Gunn Pettersen
Oddgeir Friborg
KariAnne Vrabel
Solfrid Bratland-Sanda
Mette Svendsen
Trine Stensrud
Maria Bakland
Rolf Wynn
Jorunn Sundgot-Borgen
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1312-4

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