Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
BMC Psychiatry
Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Research article

Rumination mediates the relationship between overgeneral autobiographical memory and depression in patients with major depressive disorder

Authors: Yansong Liu, Xinnian Yu, Bixiu Yang, Fuquan Zhang, Wenhua Zou, Aiguo Na, Xudong Zhao, Guangzhong Yin

Published in: BMC Psychiatry | Issue 1/2017

Login to get access

Abstract

Background

Overgeneral autobiographical memory has been identified as a risk factor for the onset and maintenance of depression. However, little is known about the underlying mechanisms that might explain overgeneral autobiographical memory phenomenon in depression. The purpose of this study was to test the mediation effects of rumination on the relationship between overgeneral autobiographical memory and depressive symptoms. Specifically, the mediation effects of brooding and reflection subtypes of rumination were examined in patients with major depressive disorder.

Methods

Eighty-seven patients with major depressive disorder completed the 17-item Hamilton Depression Rating Scale, Ruminative Response Scale, and Autobiographical Memory Test. Bootstrap mediation analysis for simple and multiple mediation models through the PROCESS macro was applied.

Results

Simple mediation analysis showed that rumination significantly mediated the relationship between overgeneral autobiographical memory and depression symptoms. Multiple mediation analyses showed that brooding, but not reflection, significantly mediated the relationship between overgeneral autobiographical memory and depression symptoms.

Conclusions

Our results indicate that global rumination partly mediates the relationship between overgeneral autobiographical memory and depressive symptoms in patients with major depressive disorder. Furthermore, the present results suggest that the mediating role of rumination in the relationship between overgeneral autobiographical memory and depression is mainly due to the maladaptive brooding subtype of rumination.
Literature
1.
2.
Williams JMG, Barnhofer T, Crane C, Herman D, Raes F, Watkins E, Dalgleish T. Autobiographical memory specificity and emotional disorder. Psychol Bull. 2007;133(1):122–48.CrossRefPubMedPubMedCentral
3.
Williams JM, Broadbent K. Autobiographical memory in suicide attempters. J Abnorm Psychol. 1986;95(2):144–9.CrossRefPubMed
4.
Liu X, Li L, Xiao J, Yang J, Jiang X. Abnormalities of autobiographical memory of patients with depressive disorders: A meta-analysis. Psychol Psychother Theory Res Pract. 2013;86(4):353–73.CrossRef
5.
Sumner JA, Griffith JW, Mineka S. Overgeneral autobiographical memory as a predictor of the course of depression: A meta-analysis. Behav Res Ther. 2010;48(7):614–25.CrossRefPubMedPubMedCentral
6.
Brittlebank AD, Scott J, Williams JM, Ferrier IN. Autobiographical memory in depression: state or trait marker? Br J Psychiatry J Ment Sci. 1993;162:118.CrossRef
7.
Peeters F, Wessel I, Merckelbach H, Boon-Vermeeren M. Autobiographical memory specificity and the course of major depressive disorder. Compr Psychiat. 2002;43(5):344–50.CrossRefPubMed
8.
Rawal A, Rice F. Examining overgeneral autobiographical memory as a risk factor for adolescent depression. J Am Acad Child Adolesc Psychiatry. 2012;51(5):518–27.CrossRefPubMed
9.
Van Daele T, Griffith JW, Van den Bergh O, Hermans D. Overgeneral autobiographical memory predicts changes in depression in a community sample. Cognit Emot. 2014;28(7):1303–12.CrossRef
10.
Hermans D, Vandromme H, Debeer E, Raes F, Demyttenaere K, Brunfaut E, Williams JMG. Overgeneral autobiographical memory predicts diagnostic status in depression. Behav Res Ther. 2008;46(5):668–77.CrossRefPubMed
11.
Sumner JA. The mechanisms underlying overgeneral autobiographical memory: An evaluative review of evidence for the CaR-FA-X model. Clin Psychol Rev. 2012;32(1):34–48.CrossRefPubMed
12.
Raes F, Hermans D, Williams JMG, Beyers W, Eelen P, Brunfaut E. Reduced autobiographical memory specificity and rumination in predicting the course of depression. J Abnorm Psychol. 2006;115(4):699–704.CrossRefPubMed
13.
Nolen-Hoeksema S, Morrow J. A prospective study of depression and posttraumatic stress symptoms after a natural disaster: the 1989 Loma Prieta Earthquake. J Pers Soc Psychol. 1991;61(1):115–21.CrossRefPubMed
14.
Nolen-Hoeksema S, Wisco BE, Lyubomirsky S. Rethinking Rumination. Perspect Psychol Sci. 2008;3(5):400–24.CrossRefPubMed
15.
16.
Raes F, Hermans D, Williams JMG, Demyttenaere K, Sabbe B, Pieters G, Eelen P. Reduced specificity of autobiographical memory: A mediator between rumination and ineffective social problem-solving in major depression? J Affect Disorders. 2005;87(2–3):331–5.CrossRefPubMed
17.
Watkins E, Teasdale JD. Adaptive and maladaptive self-focus in depression. J Affect Disorders. 2004;82(1):1–8.CrossRefPubMed
18.
Raes F, Hermans D, Williams J, Geypen L, Eelen P. The Effect of Overgeneral Autobiographical Memory Retrieval on Rumination. Psychologica Belgica. 2006;46(1-2):131–41.CrossRef
19.
Treynor W, Gonzalez R, Nolen-Hoeksema S. Rumination Reconsidered: A Psychometric Analysis. Cogn Ther Res. 2003;27(3):247–59.CrossRef
20.
Joormann J, Dkane M, Gotlib IH. Adaptive and Maladaptive Components of Rumination? Diagnostic Specificity and Relation to Depressive Biases. Behav Ther. 2006;37(3):269–80.CrossRefPubMed
21.
Raes F, Hermans D. On the mediating role of subtypes of rumination in the relationship between childhood emotional abuse and depressed mood: brooding versus reflection. Depress Anxiety. 2008;25(12):1067–70.CrossRefPubMed
22.
Debeer E, Hermans D, Raes F. Associations between components of rumination and autobiographical memory specificity as measured by a Minimal Instructions Autobiographical Memory Test. Memory. 2009;17(8):892–903.CrossRefPubMed
23.
Romero N, Vazquez C, Sanchez A. Rumination and specificity of autobiographical memory in dysphoria. Memory. 2014;22(6):646–54.CrossRefPubMed
24.
25.
Zheng YP, Zhao JP, Phillips M, Liu JB, Cai MF, Sun SQ, Huang MF. Validity and reliability of the Chinese Hamilton Depression Rating Scale. Br J Psychiatry. 1988;152:660–4.CrossRefPubMed
26.
Kong T, He Y, Auerbach RP, McWhinnie CM, Xiao J. Rumination and depression in Chinese university students: The mediating role of overgeneral autobiographical memory. Personal Individ Differ. 2015;77:221–4.CrossRef
27.
Liu X, Liu Y, Li L, Hu Y, Wu S, Yao S. Overgeneral autobiographical memory in patients with chronic pain. Pain Med. 2014;15(3):432–9.CrossRefPubMed
28.
Raes F, Hermans D, de Decker A, Eelen P, Williams JMG. Autobiographical memory specificity and affect regulation: An experimental approach. Emotion. 2003;3(2):201–6.CrossRefPubMed
29.
Preacher KJ, Hayes AF. Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav Res Methods. 2008;40(3):879–91.CrossRefPubMed
30.
Preacher KJ, Hayes AF. SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behav Res Methods Instrum Comput. 2004;36(4):717–31.CrossRefPubMed
31.
Preacher KJ, Kelley K. Effect size measures for mediation models: Quantitative strategies for communicating indirect effects. Psychol Methods. 2011;16(2):93–115.CrossRefPubMed
32.
Spinhoven P, Bockting CLH, Schene AH, Koeter MWJ, Wekking EM, Williams JMG. Autobiographical memory in the euthymic phase of recurrent depression. J Abnorm Psychol. 2006;115(3):590–600.CrossRefPubMed
33.
Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Mahway: Lawrence Erlbaum Associates; 1988.
34.
Williams JM. Capture and rumination, functional avoidance, and executive control (CaRFAX): Three processes that underlie overgeneral memory. Cogn Emot. 2006;20(3–4):548–68.CrossRefPubMed
35.
Cole DA, Maxwell SE. Testing mediational models with longitudinal data: questions and tips in the use of structural equation modeling. J Abnorm Psychol. 2003;112(4):558–77.CrossRefPubMed
Metadata
Title
Rumination mediates the relationship between overgeneral autobiographical memory and depression in patients with major depressive disorder
Authors
Yansong Liu
Xinnian Yu
Bixiu Yang
Fuquan Zhang
Wenhua Zou
Aiguo Na
Xudong Zhao
Guangzhong Yin
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1264-8

Other articles of this Issue 1/2017

BMC Psychiatry 1/2017 Go to the issue

Research article

Impaired mixed emotion processing in the right ventrolateral prefrontal cortex in schizophrenia: an fMRI study

Research article

Evaluation of a peer-delivered, transitional and post-discharge support program following psychiatric hospitalisation

Research article

Changes in event-related potentials in patients with first-episode schizophrenia and their siblings

Research article

Alterations of hair cortisol and dehydroepiandrosterone in mother-infant-dyads with maternal childhood maltreatment

Research article

Conflict-related trauma and bereavement: exploring differential symptom profiles of prolonged grief and posttraumatic stress disorder

Study protocol

Effectiveness of EMDR in patients with substance use disorder and comorbid PTSD: study protocol for a randomized controlled trial