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Published in: BMC Pediatrics 1/2019

Open Access 01-12-2019 | Research article

Prenatal alcohol exposure and infant gross motor development: a prospective cohort study

Authors: Delyse Hutchinson, George J. Youssef, Clare McCormack, Judy Wilson, Steve Allsop, Jake Najman, Elizabeth Elliott, Lucinda Burns, Sue Jacobs, Ingrid Honan, Larissa Rossen, Hannah Fiedler, Samantha Teague, Joanne Ryan, Craig A. Olsson, Richard P. Mattick

Published in: BMC Pediatrics | Issue 1/2019

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Abstract

Background

Maternal alcohol consumption in pregnancy may have adverse effects on child gross motor (GM) development. There have been few human studies on this topic, particularly ones examining low exposure. This study examined the association between prenatal alcohol exposure (PAE) and infant GM development at 12-months of age.

Methods

Participants were 1324 women recruited from antenatal clinics in Sydney and Perth, Australia. Maternal and paternal alcohol use was assessed in pregnancy via interview; offspring GM development was measured at 12-months with the Bayley Scales of Infant Development (BSID-III).

Results

Any alcohol use in pregnancy was common: 56.1%, of pregnant women drank early in Trimester one (0–6 weeks), however this reduced to 27.9% on average thereafter and at predominantly low levels. However, infant BSID GM scale scores were not found to differ significantly as a function of PAE in the first 6-weeks (low, moderate, binge or heavy PAE), nor with low PAE across pregnancy.

Conclusions

We found no evidence to suggest that low PAE is associated with measurable impairment in infant GM development at 12-months. Further research is needed to examine potential PAE impacts on GM development in heavier exposure groups and through the childhood years when subtle GM deficits may be more detectable.
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Metadata
Title
Prenatal alcohol exposure and infant gross motor development: a prospective cohort study
Authors
Delyse Hutchinson
George J. Youssef
Clare McCormack
Judy Wilson
Steve Allsop
Jake Najman
Elizabeth Elliott
Lucinda Burns
Sue Jacobs
Ingrid Honan
Larissa Rossen
Hannah Fiedler
Samantha Teague
Joanne Ryan
Craig A. Olsson
Richard P. Mattick
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2019
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-019-1516-5

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