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BMC Ophthalmology
Published in: BMC Ophthalmology 1/2020

Open Access 01-12-2020 | Glaucoma | Case report

Siderotic glaucoma without detectable intraocular foreign body in a pseudophakic eye: a case report

Authors: Yang Huang, Zi Ye, Zhaohui Li

Published in: BMC Ophthalmology | Issue 1/2020

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Abstract

Background

Ocular siderosis is induced by a retained intraocular foreign body (IOFB) containing iron and can present as siderotic glaucoma. We report a rare case of histopathologically proven siderotic glaucoma in a middle-aged blacksmith with a preceding history of ocular trauma but no radiologically detectable IOFB.

Case presentation

A 42-year-old blacksmith presented with an elevation of intraocular pressure (IOP) in left eye showing iris heterochromia and brownish deposits throughout the trabecular meshwork (TM). Preoperative ophthalmic examination did not reveal any retained IOFBs. Electroretinography showed the classic changes of retinal degeneration in ocular siderosis. Histopathologic staining of the TM verified the presence of iron deposits.

Conclusion

This case underlines the importance of the close monitoring of patients with a history of ocular trauma and highlights the necessity of electroretinography, histopathologic study, and detailed ophthalmic examination in the diagnosis of siderotic glaucoma, even if there is no definite radiologically detectable IOFB.
Literature
1.
O'Duffy D, Salmon JF. Siderosis bulbi resulting from an intralenticular foreign body. Am J Ophthalmol. 1999;127(2):218–9.CrossRef
2.
Hope-Ross M, Mahon GJ, Johnston PB. Ocular siderosis. Eye (Lond). 1993;7(Pt 3):419–25.CrossRef
3.
Schocket SS, Lakhanpal V, Varma SD. Siderosis from a retained intraocular stone. Retina. 1981;1:201–7.CrossRef
4.
Zhu L, Shen P, Lu H, Du C, Shen J, Gu Y. Ocular Trauma Score in Siderosis Bulbi With Retained Intraocular Foreign Body. Medicine (Baltimore). 2015;94:e1533.CrossRef
5.
Tawara A. Transformation and cytotoxicity of iron in siderosis bulbi. Invest Ophthalmol Vis Sci. 1986;27:226–36.PubMed
6.
Terai N, Sandner D, Kissner A, Pillunat LE. Siderosis bulbi after injury by an intraocular metal foreign body. Ophthalmologe. 2011;108:60–3.CrossRef
7.
Ding J, Yoganathan P, Fernando-Sieminski S. Resolution of siderosis glaucoma from chronic intraocular foreign body without glaucoma surgery. Can J Ophthalmol. 2015;50(5):e82–5.CrossRef
8.
Sangermani C, Mora P, Mancini C, et al. Ultrasound biomicroscopy in two cases of ocular siderosis with secondary glaucoma. Acta Ophthalmol. 2010;88(1):e1–2.CrossRef
9.
Neumann R, Belkin M, Loewenthal E, Gorodetsky R. A long-term follow-up of metallic intraocular foreign bodies, employing diagnostic x-ray spectrometry. Arch Ophthalmol. 1992;110:1269–72.CrossRef
10.
Lapira M, Karl D, Murgatroyd H. Siderosis bulbi as a consequence of a missed intraocular foreign body. BMJ Case Rep. 2014;2014.
11.
Elgin U, Eranil S, Simsek T, et al. Siderosis bulbi resulting from an unknown intraocular foreign body. J Trauma. 2008;65(4):942–3.CrossRef
12.
Koutsonas A, Plange N, Roessler GF, Walter P, Mazinani BA. A case of siderosis bulbi without a radiologically detectable foreign body. Can J Ophthalmol. 2013;48:e9–9e11.CrossRef
13.
Loporchio D, Mukkamala L, Gorukanti K, Zarbin M, Langer P, Bhagat N. Intraocular foreign bodies: a review. Surv Ophthalmol. 2016;61:582–96.CrossRef
14.
Gor DM, Kirsch CF, Leen J, Turbin R, Von Hagen S. Radiologic differentiation of intraocular glass: evaluation of imaging techniques, glass types, size, and effect of intraocular hemorrhage. AJR Am J Roentgenol. 2001;177:1199–203.CrossRef
15.
Lit ES, Young LH. Anterior and posterior segment intraocular foreign bodies. Int Ophthalmol Clin. 2002;42:107–20.CrossRef
16.
Zacks DN, Hart L, Young LH. Ultrasonography in the traumatized eye: intraocular foreign body versus artifact. Int Ophthalmol Clin. 2002;42:121–8.CrossRef
17.
Wu TT, Kung YH, Sheu SJ, Yang CA. Lens siderosis resulting from a tiny missed intralenticular foreign body. J Chin Med Assoc. 2009;72:42–4.CrossRef
18.
Fineman MS, Sharma S, Shah GK, Brown GC, Eagle RC. Ultrasound biomicroscopic diagnosis of an occult intrascleral foreign body: an unusual case of ocular siderosis. Retina. 2001;21:265–7.CrossRef
19.
Norrsell K, Sjödell L. Fuchs' heterochromic uveitis: a longitudinal clinical study. Acta Ophthalmol. 2008;86:58–64.CrossRef
20.
Zhang KK, He WW, Lu Y, Zhu XJ. Siderotic cataract with no signs of intraocular foreign body. BMC Ophthalmol. 2017;17(1):26.CrossRef
Metadata
Title
Siderotic glaucoma without detectable intraocular foreign body in a pseudophakic eye: a case report
Authors
Yang Huang
Zi Ye
Zhaohui Li
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2020
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-020-01691-8

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