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BMC Ophthalmology

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Open Access 01-12-2019 | Glaucoma | Case report

Iridocorneal endothelial syndrome in a patient with keratoconus – a case report

Authors: Michele De Maria, Danilo Iannetta, Antonio Moramarco, Luigi Fontana

Published in: BMC Ophthalmology | Issue 1/2019

Abstract

Background

To describe a case of a rare association of bilateral keratoconus and unilateral essential iris atrophy and to conduct a literature review of the current strategies of treatment of the corneal disease and glaucoma in patients with Iridocorneal Endothelial Syndrome (ICE).

Case presentation

We report a rare association of bilateral keratoconus and unilateral essential iris atrophy in a 38-year-old man. Diagnosis of bilateral keratoconus was confirmed by corneal topography. Slit-lamp examination showed extensive iris atrophy with corectopia and policoria in one eye. Corneal specular microscopy revealed an abnormal endothelium morphology in the same eye with extensive peripheral anterior synechiae and closure of the drainage angle at gonioscopy. Intraocular pressure was 26 mmHg, despite maximal topical therapy. Optic disc examination showed severe glaucomatous cupping. Surgery by glaucoma drainage device implantation was performed.

Conclusion

Essential iris atrophy is a rare clinical variant of ICE syndrome characterized by profound anatomical alterations of the anterior segment associated with corneal edema and secondary glaucoma. In these patients, selective keratoplasties have replaced penetrating keratoplasty to treat corneal decompensation and glaucoma drainage devices are preferred to conventional trabeculectomy for the treatment of secondary glaucoma.

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Title: Iridocorneal endothelial syndrome in a patient with keratoconus – a case report
Authors: Michele De Maria
Danilo Iannetta
Antonio Moramarco
Luigi Fontana
Publication date: 01-12-2019
Publisher: BioMed Central
Keywords: Glaucoma
Trabeculectomy
Keratoplasty
Published in: BMC Ophthalmology / Issue 1/2019
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-019-1215-x

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Iridocorneal endothelial syndrome in a patient with keratoconus – a case report

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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