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Published in: BMC Ophthalmology 1/2018

Open Access 01-12-2018 | Case report

Multiple evanescent white dot syndrome following rabies vaccination: a case report

Authors: Jia-song Yang, Chun-li Chen, Yu-zhang Hu, Rui Zeng

Published in: BMC Ophthalmology | Issue 1/2018

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Abstract

Background

To report a case of multiple evanescent white dot syndrome (MEWDS) following simultaneous rabies vaccination.

Case presentation

Review of the clinical, laboratory, photographic, optical coherence tomographic (OCT), fundus autofluorescent, angiographic, electrophysiologic, and perimetric records of a patient suffering from MEWDS. Results: A healthy 33-year-old Chinese female suffering from rapidly progressive visual loss of her left eye associated with photopsia and a para-central scotoma, seven days after receiving simultaneous rabies vaccination. Both anterior segments and fundus examination were unremarkable. The findings on OCT, electrophysiology, and perimetry were pathognomonic for MEWDS.

Conclusions

The clinical presentation and the benign course were consistent with the diagnosis of MEWDS. No other events could be identified as a cause, other than the rabies vaccination. This case may suggest an autoimmune basis for MEWDS in predisposed patients.
Literature
1.
go back to reference Jampol LM, Sieving PA, Pugh D, Fishman GA, Gilbert H. Multiple evanescent white dot syndrome. I Clinical findings. Archives of ophthalmology. 1984;102(5):671–4.CrossRefPubMed Jampol LM, Sieving PA, Pugh D, Fishman GA, Gilbert H. Multiple evanescent white dot syndrome. I Clinical findings. Archives of ophthalmology. 1984;102(5):671–4.CrossRefPubMed
2.
go back to reference dell'Omo R, Pavesio CE. Multiple evanescent white dot syndrome (MEWDS). Int Ophthalmol Clin. 2012;52(4):221–8.CrossRefPubMed dell'Omo R, Pavesio CE. Multiple evanescent white dot syndrome (MEWDS). Int Ophthalmol Clin. 2012;52(4):221–8.CrossRefPubMed
3.
go back to reference Fooks AR, Cliquet F, Finke S, Freuling C, Hemachudha T, Mani RS, Muller T, Nadin-Davis S, Picard-Meyer E, Wilde H, et al. Rabies. Nature reviews Disease primers. 2017;3:17091.CrossRefPubMed Fooks AR, Cliquet F, Finke S, Freuling C, Hemachudha T, Mani RS, Muller T, Nadin-Davis S, Picard-Meyer E, Wilde H, et al. Rabies. Nature reviews Disease primers. 2017;3:17091.CrossRefPubMed
4.
go back to reference Fine L, Fine A, Cunningham ET Jr. Multiple evanescent white dot syndrome following hepatitis a vaccination. Arch Ophthalmol. 2001;119(12):1856–8.CrossRefPubMed Fine L, Fine A, Cunningham ET Jr. Multiple evanescent white dot syndrome following hepatitis a vaccination. Arch Ophthalmol. 2001;119(12):1856–8.CrossRefPubMed
5.
go back to reference Stangos A, Zaninetti M, Petropoulos I, Baglivo E, Pournaras C. Multiple evanescent white dot syndrome following simultaneous hepatitis-a and yellow fever vaccination. Ocul Immunol Inflamm. 2006;14(5):301–4.CrossRefPubMed Stangos A, Zaninetti M, Petropoulos I, Baglivo E, Pournaras C. Multiple evanescent white dot syndrome following simultaneous hepatitis-a and yellow fever vaccination. Ocul Immunol Inflamm. 2006;14(5):301–4.CrossRefPubMed
6.
go back to reference Cohen SM. Multiple evanescent white dot syndrome after vaccination for human papilloma virus and meningococcus. J Pediatr Ophthalmol Strabismus. 2009. Cohen SM. Multiple evanescent white dot syndrome after vaccination for human papilloma virus and meningococcus. J Pediatr Ophthalmol Strabismus. 2009.
7.
go back to reference Goyal S, Nazarian SM, Thayi DR, Hammond F, Petrovic V. Multiple evanescent white dot syndrome following recent influenza vaccination. Can J Ophthalmol. 2013;48(5):e115–6.CrossRefPubMed Goyal S, Nazarian SM, Thayi DR, Hammond F, Petrovic V. Multiple evanescent white dot syndrome following recent influenza vaccination. Can J Ophthalmol. 2013;48(5):e115–6.CrossRefPubMed
8.
go back to reference Cahuzac A, Wolff B, Mathis T, Errera MH, Sahel JA, Mauget-Faysse M. Multimodal imaging findings in ‘hyper-early’ stage MEWDS. Br J Ophthalmol. 2017;101(10):1381–5.CrossRefPubMed Cahuzac A, Wolff B, Mathis T, Errera MH, Sahel JA, Mauget-Faysse M. Multimodal imaging findings in ‘hyper-early’ stage MEWDS. Br J Ophthalmol. 2017;101(10):1381–5.CrossRefPubMed
9.
go back to reference Mrejen S, Khan S, Gallego-Pinazo R, Jampol LM, Yannuzzi LA. Acute zonal occult outer retinopathy: a classification based on multimodal imaging. JAMA ophthalmology. 2014;132(9):1089–98.CrossRefPubMed Mrejen S, Khan S, Gallego-Pinazo R, Jampol LM, Yannuzzi LA. Acute zonal occult outer retinopathy: a classification based on multimodal imaging. JAMA ophthalmology. 2014;132(9):1089–98.CrossRefPubMed
Metadata
Title
Multiple evanescent white dot syndrome following rabies vaccination: a case report
Authors
Jia-song Yang
Chun-li Chen
Yu-zhang Hu
Rui Zeng
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2018
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-018-0968-y

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