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BMC Ophthalmology

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Open Access 01-12-2018 | Research article

Decreased choroidal thickness in vitiligo patients

Authors: Serkan Demirkan, Zafer Onaran, Güzin Samav, Fatma Özkal, Erhan Yumuşak, Özgür Gündüz, Ayşe Karabulut

Published in: BMC Ophthalmology | Issue 1/2018

Abstract

Background

Vitiligo is a disease characterized by depigmented macules and patches that occur as a result of the loss of functional melanocytes from the affected skin through a mechanism which has not been elucidated yet. Destruction of pigment cells in vitiligo may not remain limited to the skin; the eyelashes, iris, ciliary body, choroid, retinal pigment epithelium and meninges may also be affected. This study aims to compare the choroidal thickness of patients with and without vitiligo using optical coherence tomography (OCT).

Methods

Spectral-domain optical coherence tomography (SD-OCT) (Retina Scan Advanced RS-3000 NIDEK, Japan) instrument (with λ = 840 nm, 27,000 A-scans/second and 5 μm axial resolution) was used for the imaging. Statistical analysis was performed using SPSS 21.0 software package.

Results

In all values except optic nevre area measurements, the choroidal thickness of all vitiligo patients was found out to be thinner compared to the control group.

Conclusions

In vitiligo, the choroidal thickness may be affected by the loss of melanocytes.

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Title: Decreased choroidal thickness in vitiligo patients
Authors: Serkan Demirkan
Zafer Onaran
Güzin Samav
Fatma Özkal
Erhan Yumuşak
Özgür Gündüz
Ayşe Karabulut
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2018
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-018-0796-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Decreased choroidal thickness in vitiligo patients

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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