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BMC Ophthalmology

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Open Access 01-12-2016 | Case report

Intravitreal ranibizumab for choroidal neovascularization in a patient with angioid streaks and multiple evanescent white dots

Authors: Alfredo Pece, Davide Allegrini, Stelios Kontadakis, Giuseppe Querques, Luca Rossetti

Published in: BMC Ophthalmology | Issue 1/2016

Abstract

Background

To report a patient with angioid streaks (ASs) and coincident multiple evanescent white dot syndrome (MEWDS) who developed choroidal neovascularization (CNV).

Case presentation

A 20-year-old woman presented with reduced vision (20/100) in her left eye (LE). Based on a complete ophthalmologic examination the patient was diagnosed with ASs and coincident MEWDS. Two weeks later best-corrected visual acuity (BCVA) improved up to 20/25 and the MEWDS findings almost disappeared. Two months later BCVA dropped again (20/100) due to the development of CNV which was treated by a single intravitreal injection of ranibizumab (0.5 mg/0.05 mL). One month after this BCVA improved up to 20/40, and there was regression of the CNV. There was no need for retreatment at the last follow-up visit, 1 year after the ranibizumab injection, when the patient showed further recovery of BCVA up to 20/25.

Conclusions

In this case of ASs, MEWDS completely resolved after 2 weeks, but 2 months later CNV developed. A single intravitreal injection of ranibizumab had a long-lasting effect. Larger series are necessary to clarify the pathogenesis of CNV in such cases and the role of intravitreal ranibizumab.

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Title: Intravitreal ranibizumab for choroidal neovascularization in a patient with angioid streaks and multiple evanescent white dots
Authors: Alfredo Pece
Davide Allegrini
Stelios Kontadakis
Giuseppe Querques
Luca Rossetti
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2016
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-016-0307-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Intravitreal ranibizumab for choroidal neovascularization in a patient with angioid streaks and multiple evanescent white dots

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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