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BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2016

Open Access 01-12-2016 | Research article

Awareness of cytomegalovirus and risk factors for susceptibility among pregnant women, in Montreal, Canada

Authors: Sarah Wizman, Valérie Lamarre, Lena Coic, Fatima Kakkar, Jean-Baptiste Le Meur, Céline Rousseau, Marc Boucher, Bruce Tapiero

Published in: BMC Pregnancy and Childbirth | Issue 1/2016

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Abstract

Background

Advances in diagnostic and therapeutic modalities for congenital cytomegalovirus (CMV) infection have generated a mounting interest in identifying mothers susceptible to CMV. The objectives of this study were to evaluate the prevalence and socio-demographic determinants of CMV susceptibility and CMV awareness, among pregnant women, in Montreal, Quebec.

Methods

Between April and December 2012, women delivering at Centre Hospitalier Universitaire Sainte Justine were recruited for the study. Stored serum from the first trimester of pregnancy was tested for CMV IgG. Knowledge about CMV and socio-demographic characteristics were collected via standardized questionnaire.

Results

Four hundred and ninety one women were enrolled in the study. Overall, 225 mothers (46 %) were seronegative for CMV, and 85 % (n = 415) were unaware of CMV or the associated risks in pregnancy. Significant risk factors for CMV seronegative status included Canadian vs. foreign born (aOR 6.88, 95 % CI 4.33–10.94), and high vs. low family income (aOR 4.68, 95 % CI 2.09–10.48). Maternal employment status was the only significant predictor of CMV unawareness, with unemployed mothers at the highest risk (aOR 85.6, 95 % CI 17.3–421.3).

Conclusions

Nearly half of pregnant women studied were at risk of primary infection, and yet, the majority was unaware of potential risks associated with CMV. Canadian born mothers and those with a high socioeconomic status were more likely to be CMV seronegative. Increased education about CMV infection, through public health interventions and obstetrician/pediatric counseling, is needed for all pregnant women.
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Metadata
Title
Awareness of cytomegalovirus and risk factors for susceptibility among pregnant women, in Montreal, Canada
Authors
Sarah Wizman
Valérie Lamarre
Lena Coic
Fatima Kakkar
Jean-Baptiste Le Meur
Céline Rousseau
Marc Boucher
Bruce Tapiero
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2016
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-016-0844-9

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