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Published in: BMC Women's Health 1/2014

Open Access 01-12-2014 | Research article

Educating women about congenital cytomegalovirus: assessment of health education materials through a web-based survey

Authors: Simani M Price, Erika Bonilla, Paul Zador, Denise M Levis, Christina L Kilgo, Michael J Cannon

Published in: BMC Women's Health | Issue 1/2014

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Abstract

Background

Congenital cytomegalovirus (CMV) is the most common congenital infection in the U.S. and can result in permanent disabilities, such as hearing and vision loss, intellectual disability, and psychomotor and language impairments. Women can adopt prevention behaviors in an attempt to reduce their exposure to CMV. Currently, few women are familiar with CMV. To increase awareness of CMV, the Centers for Disease Control and Prevention (CDC) developed draft health education materials. The purpose of this study was to pilot test two health education materials to gauge their appeal and to determine if they increase knowledge about CMV and motivate audiences to seek additional information on CMV and adopt CMV prevention behaviors.

Methods

African-American (n = 404) and Caucasian women (n = 405), who had a young child and were either pregnant or planning a pregnancy, were recruited to participate in a 15-minute web survey. Participants were randomly assigned to view one of two CMV health education materials, either a factsheet or video. Pre and post survey measures were used to assess changes in knowledge of CMV and motivation to adopt prevention behaviors. We also examined audience preferences regarding materials and motivation.

Results

CMV knowledge score increased significantly after presentation of either the video or factsheet (from 3.7 out of 10 to 9.1 out of 10, p <0.001). The average materials appeal score was high, with a mean of 3.6 on a four-point scale, indicating women responded very positively to both materials. Regression analyses indicated that appeal, message involvement (e.g., information seeking, discussing with others), post materials knowledge score, and viewing the video (vs. factsheet) were significantly positively associated with increased support for CMV prevention behaviors.

Conclusions

Overall, we found that the health education materials improved women’s knowledge of CMV and encouraged them to adopt prevention behaviors. Given the low awareness levels among women currently, these findings suggest that appropriate education materials have the potential to greatly increase knowledge of CMV.
As women become more knowledgeable about CMV and transmission routes, we expect they will be more likely to adopt prevention behaviors, thereby reducing their risk of CMV infection.
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Literature
1.
go back to reference Arvin AM, Fast P, Myers M, Plotkin S, Rabinovich R: Vaccine development to prevent cytomegalovirus disease: report from the National Vaccine Advisory Committee. Clin Infect Dis. 2004, 39 (2): 233-239. 10.1086/421999.CrossRefPubMed Arvin AM, Fast P, Myers M, Plotkin S, Rabinovich R: Vaccine development to prevent cytomegalovirus disease: report from the National Vaccine Advisory Committee. Clin Infect Dis. 2004, 39 (2): 233-239. 10.1086/421999.CrossRefPubMed
2.
go back to reference Dollard SC, Grosse SD, Ross DS: New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Rev Med Virol. 2007, 17 (5): 355-363. 10.1002/rmv.544.CrossRefPubMed Dollard SC, Grosse SD, Ross DS: New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Rev Med Virol. 2007, 17 (5): 355-363. 10.1002/rmv.544.CrossRefPubMed
3.
go back to reference Kenneson A, Cannon MJ: Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection. Rev Med Virol. 2007, 17 (4): 253-276. 10.1002/rmv.535.CrossRefPubMed Kenneson A, Cannon MJ: Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection. Rev Med Virol. 2007, 17 (4): 253-276. 10.1002/rmv.535.CrossRefPubMed
4.
go back to reference Mocarski ES, Shenk T, Pass RF: Cytomegaloviruses. Fields’ Virology. Edited by: Knipe DM, Howley PM. 2007, Lippincott Williams & Wilkins, Philadelphia, 2702-2772. 5 Mocarski ES, Shenk T, Pass RF: Cytomegaloviruses. Fields’ Virology. Edited by: Knipe DM, Howley PM. 2007, Lippincott Williams & Wilkins, Philadelphia, 2702-2772. 5
5.
go back to reference Boppana SB, Rivera LB, Fowler KB, Mach M, Britt WJ: Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity. N Engl J Med. 2001, 344 (18): 1366-1371. 10.1056/NEJM200105033441804.CrossRefPubMed Boppana SB, Rivera LB, Fowler KB, Mach M, Britt WJ: Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity. N Engl J Med. 2001, 344 (18): 1366-1371. 10.1056/NEJM200105033441804.CrossRefPubMed
6.
go back to reference Nyholm JL, Schleiss MR: Prevention of maternal cytomegalovirus infection: current status and future prospects. Int J Women Health. 2010, 2: 23-35. Nyholm JL, Schleiss MR: Prevention of maternal cytomegalovirus infection: current status and future prospects. Int J Women Health. 2010, 2: 23-35.
7.
go back to reference Cannon MJ, Hyde TB, Schmid DS: Review of cytomegalovirus shedding in bodily fluids and relevance to congenital cytomegalovirus infection. Rev Med Virol. 2011, 21 (4): 240-255. 10.1002/rmv.695.CrossRefPubMedPubMedCentral Cannon MJ, Hyde TB, Schmid DS: Review of cytomegalovirus shedding in bodily fluids and relevance to congenital cytomegalovirus infection. Rev Med Virol. 2011, 21 (4): 240-255. 10.1002/rmv.695.CrossRefPubMedPubMedCentral
8.
go back to reference Hyde TB, Schmid DS, Cannon MJ: Cytomegalovirus seroconversion rates and risk factors: implications for congenital CMV. Rev Med Virol. 2010, 20 (5): 311-326. 10.1002/rmv.659.CrossRefPubMed Hyde TB, Schmid DS, Cannon MJ: Cytomegalovirus seroconversion rates and risk factors: implications for congenital CMV. Rev Med Virol. 2010, 20 (5): 311-326. 10.1002/rmv.659.CrossRefPubMed
9.
go back to reference Adler SP: Cytomegalovirus and child day care. Evidence for an increased infection rate among day-care workers. N Engl J Med. 1989, 321 (19): 1290-1296. 10.1056/NEJM198911093211903.CrossRefPubMed Adler SP: Cytomegalovirus and child day care. Evidence for an increased infection rate among day-care workers. N Engl J Med. 1989, 321 (19): 1290-1296. 10.1056/NEJM198911093211903.CrossRefPubMed
10.
go back to reference Pass RF, Little EA, Stagno S, Britt WJ, Alford CA: Young children as a probable source of maternal and congenital cytomegalovirus infection. N Engl J Med. 1987, 316 (22): 1366-1370. 10.1056/NEJM198705283162203.CrossRefPubMed Pass RF, Little EA, Stagno S, Britt WJ, Alford CA: Young children as a probable source of maternal and congenital cytomegalovirus infection. N Engl J Med. 1987, 316 (22): 1366-1370. 10.1056/NEJM198705283162203.CrossRefPubMed
11.
go back to reference Red Book: 2012 Report of the Committee on Infectious Diseases. 2012, American Academy of Pediatrics, Elk Grove Village, IL, 29 Red Book: 2012 Report of the Committee on Infectious Diseases. 2012, American Academy of Pediatrics, Elk Grove Village, IL, 29
12.
go back to reference Perinatal Viral and Parasitic Infections. ACOG Practice Bulletin 20. 2000, ACOG, Washington, DC Perinatal Viral and Parasitic Infections. ACOG Practice Bulletin 20. 2000, ACOG, Washington, DC
13.
go back to reference Vauloup-Fellous C, Picone O, Cordier A-G, Parent-du-Chatelet I, Senat M-V, Frydman R, Grangeot-Keros L: Does hygiene counseling have an impact on the rate of CMV primary infection during pregnancy? Results of a 3-year prospective study in a French hospital. J Clin Virol. 2009, 46S: S49-S53. 10.1016/j.jcv.2009.09.003.CrossRef Vauloup-Fellous C, Picone O, Cordier A-G, Parent-du-Chatelet I, Senat M-V, Frydman R, Grangeot-Keros L: Does hygiene counseling have an impact on the rate of CMV primary infection during pregnancy? Results of a 3-year prospective study in a French hospital. J Clin Virol. 2009, 46S: S49-S53. 10.1016/j.jcv.2009.09.003.CrossRef
14.
go back to reference Adler SP, Finney JW, Manganello AM, Best AM: Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors: a randomized controlled trial. Pediatr Infect Dis J. 1996, 15 (3): 240-246. 10.1097/00006454-199603000-00013.CrossRefPubMed Adler SP, Finney JW, Manganello AM, Best AM: Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors: a randomized controlled trial. Pediatr Infect Dis J. 1996, 15 (3): 240-246. 10.1097/00006454-199603000-00013.CrossRefPubMed
15.
go back to reference Jeon J, Victor M, Adler S, Arwady A, Demmler G, Fowler K, Goldfarb J, Keyserling H, Massoudi M, Richards K, Staras SAS, Cannon MJ: Knowledge and awareness of congenital cytomegalovirus among women. Infect Dis Obstet Gynecol. 2006, 2006: 1-7. 10.1155/IDOG/2006/80383.CrossRef Jeon J, Victor M, Adler S, Arwady A, Demmler G, Fowler K, Goldfarb J, Keyserling H, Massoudi M, Richards K, Staras SAS, Cannon MJ: Knowledge and awareness of congenital cytomegalovirus among women. Infect Dis Obstet Gynecol. 2006, 2006: 1-7. 10.1155/IDOG/2006/80383.CrossRef
16.
go back to reference Ross DS, Victor M, Sumartojo E, Cannon MJ: Women’s knowledge of congenital cytomegalovirus: results from the 2005 HealthStyles survey. J Womens Health (Larchmt). 2008, 17 (5): 849-858. 10.1089/jwh.2007.0523.CrossRef Ross DS, Victor M, Sumartojo E, Cannon MJ: Women’s knowledge of congenital cytomegalovirus: results from the 2005 HealthStyles survey. J Womens Health (Larchmt). 2008, 17 (5): 849-858. 10.1089/jwh.2007.0523.CrossRef
17.
go back to reference Khanna R, Diamond DJ: Human cytomegalovirus vaccine: time to look for alternative options. Trends Mol Med. 2006, 12 (1): 26-33. 10.1016/j.molmed.2005.11.006.CrossRefPubMed Khanna R, Diamond DJ: Human cytomegalovirus vaccine: time to look for alternative options. Trends Mol Med. 2006, 12 (1): 26-33. 10.1016/j.molmed.2005.11.006.CrossRefPubMed
18.
go back to reference Pass RF, Zhang C, Evans A, Simpson T, Andrews W, Huang ML, Corey L, Hill J, Davis E, Flanigan C, Cloud G: Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med. 2009, 360 (12): 1191-1199. 10.1056/NEJMoa0804749.CrossRefPubMedPubMedCentral Pass RF, Zhang C, Evans A, Simpson T, Andrews W, Huang ML, Corey L, Hill J, Davis E, Flanigan C, Cloud G: Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med. 2009, 360 (12): 1191-1199. 10.1056/NEJMoa0804749.CrossRefPubMedPubMedCentral
19.
go back to reference Schleiss MR: Cytomegalovirus vaccine development. Hum Cytomegalovirus. 2008, 325: 361-382. 10.1007/978-3-540-77349-8_20.CrossRef Schleiss MR: Cytomegalovirus vaccine development. Hum Cytomegalovirus. 2008, 325: 361-382. 10.1007/978-3-540-77349-8_20.CrossRef
20.
go back to reference Kimberlin DW, Lin CY, Sanchez PJ, Demmler GJ, Dankner W, Shelton M, Jacobs RF, Vaudry W, Pass RF, Kiell JM, Soong S-J, Whitley RJ: Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial. J Pediatr. 2003, 143 (1): 16-25. 10.1016/S0022-3476(03)00192-6.CrossRefPubMed Kimberlin DW, Lin CY, Sanchez PJ, Demmler GJ, Dankner W, Shelton M, Jacobs RF, Vaudry W, Pass RF, Kiell JM, Soong S-J, Whitley RJ: Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial. J Pediatr. 2003, 143 (1): 16-25. 10.1016/S0022-3476(03)00192-6.CrossRefPubMed
21.
go back to reference Nigro G, Adler SP, La Torre R, Best AM: Passive immunization during pregnancy for congenital cytomegalovirus infection. N Engl J Med. 2005, 353 (13): 1350-1362. 10.1056/NEJMoa043337.CrossRefPubMed Nigro G, Adler SP, La Torre R, Best AM: Passive immunization during pregnancy for congenital cytomegalovirus infection. N Engl J Med. 2005, 353 (13): 1350-1362. 10.1056/NEJMoa043337.CrossRefPubMed
22.
go back to reference Revello MG, Lazzarotto T, Guerra B, Spinillo A, Ferrazzi E, Kustermann A, Guaschino S, Vergani P, Todros T, Frusca T, Arossa A, Furione M, Rognoni V, Rizzo N, Gabrielli L, Klersy C, Gerna G: A randomized trial of hyperimmune globulin to prevent congenital cytomegalovirus. N Engl J Med. 2014, 370 (14): 1316-1326. 10.1056/NEJMoa1310214.CrossRefPubMed Revello MG, Lazzarotto T, Guerra B, Spinillo A, Ferrazzi E, Kustermann A, Guaschino S, Vergani P, Todros T, Frusca T, Arossa A, Furione M, Rognoni V, Rizzo N, Gabrielli L, Klersy C, Gerna G: A randomized trial of hyperimmune globulin to prevent congenital cytomegalovirus. N Engl J Med. 2014, 370 (14): 1316-1326. 10.1056/NEJMoa1310214.CrossRefPubMed
23.
24.
go back to reference Bate SL, Dollard SC, Cannon MJ: Cytomegalovirus seroprevalence in the United States: the national health and nutrition examination surveys, 1988-2004. Clin Infect Dis. 2010, 50 (11): 1439-1447. 10.1086/652438.CrossRefPubMed Bate SL, Dollard SC, Cannon MJ: Cytomegalovirus seroprevalence in the United States: the national health and nutrition examination surveys, 1988-2004. Clin Infect Dis. 2010, 50 (11): 1439-1447. 10.1086/652438.CrossRefPubMed
25.
go back to reference Petty RE, Cacioppo JT: Attitudes and Persuasion: Classic and Contemporary Approaches. 1981, Westview Press, Inc., Dubuque, IA Petty RE, Cacioppo JT: Attitudes and Persuasion: Classic and Contemporary Approaches. 1981, Westview Press, Inc., Dubuque, IA
26.
go back to reference Murphy PW, Chesson AL, Walker L, Arnold CL, Chesson LM: Comparing the effectiveness of video and written material for improving knowledge among sleep disorders clinic patients with limited literacy skills. South Med J. 2000, 93 (3): 297-304. 10.1097/00007611-200003000-00010.CrossRefPubMed Murphy PW, Chesson AL, Walker L, Arnold CL, Chesson LM: Comparing the effectiveness of video and written material for improving knowledge among sleep disorders clinic patients with limited literacy skills. South Med J. 2000, 93 (3): 297-304. 10.1097/00007611-200003000-00010.CrossRefPubMed
27.
go back to reference Wiese HJ, Boethel C, Phillips B, Wilson JF, Peters J, Viggiano T: CPAP compliance: video education may help!. Sleep Med. 2005, 6 (2): 171-174. 10.1016/j.sleep.2004.08.006.CrossRef Wiese HJ, Boethel C, Phillips B, Wilson JF, Peters J, Viggiano T: CPAP compliance: video education may help!. Sleep Med. 2005, 6 (2): 171-174. 10.1016/j.sleep.2004.08.006.CrossRef
28.
go back to reference Campbell T, Dunt D, Fitzgerald JL, Gordon I: The impact of patient narratives on self-efficacy and self-care in Australians with type 2 diabetes: Stage 1 results of a randomized trial. Health Promot Int 2013, Aug 28 (Epub ahead of print). Campbell T, Dunt D, Fitzgerald JL, Gordon I: The impact of patient narratives on self-efficacy and self-care in Australians with type 2 diabetes: Stage 1 results of a randomized trial. Health Promot Int 2013, Aug 28 (Epub ahead of print).
29.
go back to reference Hinyard LJ, Kreuter MW: Using narrative communication as a tool for health behavior change: A conceptual, theoretical, and empirical overview. Health Educ Behav. 2007, 34 (5): 777-792. 10.1177/1090198106291963.CrossRefPubMed Hinyard LJ, Kreuter MW: Using narrative communication as a tool for health behavior change: A conceptual, theoretical, and empirical overview. Health Educ Behav. 2007, 34 (5): 777-792. 10.1177/1090198106291963.CrossRefPubMed
30.
go back to reference Kreuter MW, McClure SM: The role of culture in health communication. Annu Rev Publ Health. 2004, 25: 439-455. 10.1146/annurev.publhealth.25.101802.123000.CrossRef Kreuter MW, McClure SM: The role of culture in health communication. Annu Rev Publ Health. 2004, 25: 439-455. 10.1146/annurev.publhealth.25.101802.123000.CrossRef
Metadata
Title
Educating women about congenital cytomegalovirus: assessment of health education materials through a web-based survey
Authors
Simani M Price
Erika Bonilla
Paul Zador
Denise M Levis
Christina L Kilgo
Michael J Cannon
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2014
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-014-0144-3

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