Skip to main content
Top
Published in: BMC Pregnancy and Childbirth 1/2015

Open Access 01-12-2015 | Research article

Incidence and determinants of severe maternal morbidity: a transversal study in a referral hospital in Teresina, Piaui, Brazil

Authors: Alberto Pereira Madeiro, Andréa Cronemberger Rufino, Érica Zânia Gonçalves Lacerda, Laís Gonçalves Brasil

Published in: BMC Pregnancy and Childbirth | Issue 1/2015

Login to get access

Abstract

Background

Maternal near miss (MNM) investigation is a useful tool for monitoring standards for obstetric care. This study evaluated the prevalence and the determinants of severe maternal morbidity (SMM) and MNM in a tertiary referral hospital in Teresina, Piauí, Brazil.

Methods

A transversal and prospective study was conducted between September 2012 and February 2013. The cases were included according to criteria established by the WHO. Odds ratio, their respective confidence intervals, and multivariate analyses were examined.

Results

Five thousand eight hundred forty one live births, 343 women with SMM, 56 cases of MNM, and 10 maternal deaths were investigated. The rate for severe maternal outcomes was 11.2 cases per 1000 live births, the rate of MNM was 9.6 cases/1000 live births, and the rate for mortality was 171.2 cases/100,000 live births. Management criteria were most frequently observed among MNM/death cases. Hypertensive diseases (86.1 %) and hemorrhagic complications (10.0 %) were the main determinants of MNM, but infectious abortion was the most common isolated cause of maternal death. There was a correlation between MNM/death and hospitalized more than 5 days (p = 0.023) and between termination of pregnancy by cesarean (p = 0.002) and APGAR < 7 in the 1st minute (p = 0.015).

Conclusions

SMM and MNM were quite prevalent in the population studied. Women whose condition progressed to MNM/death had a higher association with terminating pregnancy by cesarean, longer hospitalization times, and worse perinatal results. The results from the study can be useful to improve the quality of obstetric care and consequently diminish maternal mortality in the region.
Literature
1.
go back to reference Hogan MC, Foreman KJ, Naghavi M, Ahn SY, Wang M, Makela SM, et al. Maternal mortality for 181 countries, 1980–2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet. 2010;375(9726):1609–23.CrossRefPubMed Hogan MC, Foreman KJ, Naghavi M, Ahn SY, Wang M, Makela SM, et al. Maternal mortality for 181 countries, 1980–2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet. 2010;375(9726):1609–23.CrossRefPubMed
3.
go back to reference Szwarcwald CL, Escalante JJC, Rabello Neto DL, Souza Jr PRB, Victora CG. Estimation of maternal mortality rates in Brazil, 2008–2011. Cad Saude Publica. 2014;30(suppl):S71–83.CrossRef Szwarcwald CL, Escalante JJC, Rabello Neto DL, Souza Jr PRB, Victora CG. Estimation of maternal mortality rates in Brazil, 2008–2011. Cad Saude Publica. 2014;30(suppl):S71–83.CrossRef
4.
go back to reference Laurenti R, Jorge MHPM, Gotlieb SLD. Maternal mortality in Brazilian State Capitals: some characteristics and estimates for an adjustment factor. Rev Bras Epidemiol. 2004;7(4):449–60.CrossRef Laurenti R, Jorge MHPM, Gotlieb SLD. Maternal mortality in Brazilian State Capitals: some characteristics and estimates for an adjustment factor. Rev Bras Epidemiol. 2004;7(4):449–60.CrossRef
5.
go back to reference Deneux-Tharaux C, Berg C, Bouvier-Colle MH, Gissler M, Harper M, Nannini A, et al. Underreporting of pregnancy-related mortality in the United States and Europe. Obstet Gynecol. 2005;106(4):684–92.CrossRefPubMed Deneux-Tharaux C, Berg C, Bouvier-Colle MH, Gissler M, Harper M, Nannini A, et al. Underreporting of pregnancy-related mortality in the United States and Europe. Obstet Gynecol. 2005;106(4):684–92.CrossRefPubMed
6.
go back to reference Pattinson RC, Buchmann E, Mantel G, Schoon M, Rees H. Can enquiries into severe acute maternal morbidity act as a surrogate for maternal death enquiries? BJOG. 2003;110(10):889–93.CrossRefPubMed Pattinson RC, Buchmann E, Mantel G, Schoon M, Rees H. Can enquiries into severe acute maternal morbidity act as a surrogate for maternal death enquiries? BJOG. 2003;110(10):889–93.CrossRefPubMed
7.
go back to reference Souza JP, Cecatti JG, Parpinelli MA, Sousa MH, Serruya SJ. Systematic review of near miss maternal morbidity. Cad Saude Publica. 2006;22(2):255–64.CrossRefPubMed Souza JP, Cecatti JG, Parpinelli MA, Sousa MH, Serruya SJ. Systematic review of near miss maternal morbidity. Cad Saude Publica. 2006;22(2):255–64.CrossRefPubMed
8.
go back to reference Stones W, Lim W, Al-Azzawi F, Kelly M. An investigation of maternal morbidity with identification of life-threatening near miss episodes. Health Trends. 1991;23(1):13–5.PubMed Stones W, Lim W, Al-Azzawi F, Kelly M. An investigation of maternal morbidity with identification of life-threatening near miss episodes. Health Trends. 1991;23(1):13–5.PubMed
9.
go back to reference Souza JP, Cecatti JG, Faúndes A, Morais SS, Villar J, Carroli G, et al. Maternal near miss and maternal death in the World Health Organization’s 2005 global survey on maternal and perinatal health. Bull World Health Organ. 2010;88(2):113–9.CrossRefPubMed Souza JP, Cecatti JG, Faúndes A, Morais SS, Villar J, Carroli G, et al. Maternal near miss and maternal death in the World Health Organization’s 2005 global survey on maternal and perinatal health. Bull World Health Organ. 2010;88(2):113–9.CrossRefPubMed
10.
go back to reference Geller SE, Rosenberger D, Cox SM, Brown ML, Simonson L, Driscoll CA, et al. The continuum of maternal morbidity and mortality: factors associated with severity. Am J Obstet Gynecol. 2004;191(3):939–44.CrossRefPubMed Geller SE, Rosenberger D, Cox SM, Brown ML, Simonson L, Driscoll CA, et al. The continuum of maternal morbidity and mortality: factors associated with severity. Am J Obstet Gynecol. 2004;191(3):939–44.CrossRefPubMed
11.
go back to reference Pattinson RC, Hall M. Near misses: a useful adjunct to maternal death enquires. Br Med Bull. 2003;67(1):231–43.CrossRefPubMed Pattinson RC, Hall M. Near misses: a useful adjunct to maternal death enquires. Br Med Bull. 2003;67(1):231–43.CrossRefPubMed
12.
go back to reference Say L, Souza JP, Pattinson RC. Maternal near miss – towards a standard tool for monitoring quality of maternal health care. Best Pract Res Clin Obstet Gynaecol. 2009;23(3):287–96.CrossRefPubMed Say L, Souza JP, Pattinson RC. Maternal near miss – towards a standard tool for monitoring quality of maternal health care. Best Pract Res Clin Obstet Gynaecol. 2009;23(3):287–96.CrossRefPubMed
13.
14.
go back to reference Tunçalp O, Hindin MJ, Souza JP, Chou D, Say L. The prevalence of maternal near miss: a systematic review. BJOG. 2012;119(6):653–61.CrossRefPubMed Tunçalp O, Hindin MJ, Souza JP, Chou D, Say L. The prevalence of maternal near miss: a systematic review. BJOG. 2012;119(6):653–61.CrossRefPubMed
15.
go back to reference Zwart JJ, Dupuis JRO, Richters A, Öry F, van Roosmalen J. Obstetric intensive care unit admission: a 2-year nationwide population-based cohort study. Intensive Care Med. 2010;36(2):256–63.CrossRefPubMed Zwart JJ, Dupuis JRO, Richters A, Öry F, van Roosmalen J. Obstetric intensive care unit admission: a 2-year nationwide population-based cohort study. Intensive Care Med. 2010;36(2):256–63.CrossRefPubMed
16.
go back to reference Souza JP, Cecatti JG, Haddad SM, Parpinelli MA, Costa ML, Katz L, et al. The WHO maternal near-miss approach and the maternal severity index model (MSI): tools for accessing the management of severe maternal morbidity. PLoS One. 2012;7(8), e44129.CrossRefPubMedPubMedCentral Souza JP, Cecatti JG, Haddad SM, Parpinelli MA, Costa ML, Katz L, et al. The WHO maternal near-miss approach and the maternal severity index model (MSI): tools for accessing the management of severe maternal morbidity. PLoS One. 2012;7(8), e44129.CrossRefPubMedPubMedCentral
17.
go back to reference Oliveira Jr FC, Surita FG, Pinto e Silva JL, Cecatti JG, Parpinelli MA, Haddad SM, et al. Severe maternal morbidity and maternal near miss in the extremes of reproductive age: results from a national cross-sectional multicenter study. BMC Pregnancy Childbirth. 2014;14:77.CrossRefPubMedPubMedCentral Oliveira Jr FC, Surita FG, Pinto e Silva JL, Cecatti JG, Parpinelli MA, Haddad SM, et al. Severe maternal morbidity and maternal near miss in the extremes of reproductive age: results from a national cross-sectional multicenter study. BMC Pregnancy Childbirth. 2014;14:77.CrossRefPubMedPubMedCentral
18.
go back to reference Zanette E, Parpinelli MA, Surita FG, Costa ML, Haddad SM, Sousa MH, et al. Maternal near miss and death among women with severe hypertensive disorders: a Brazilian multicenter surveillance study. Reprod Health. 2014;11(1):4.CrossRefPubMedPubMedCentral Zanette E, Parpinelli MA, Surita FG, Costa ML, Haddad SM, Sousa MH, et al. Maternal near miss and death among women with severe hypertensive disorders: a Brazilian multicenter surveillance study. Reprod Health. 2014;11(1):4.CrossRefPubMedPubMedCentral
19.
go back to reference Lotufo FA, Parpinelli MA, Haddad SM, Surita FG, Cecatti JG. Applying the new concept of maternal near-miss in an intensive care. Clinics. 2012;67(3):225–30.CrossRefPubMedPubMedCentral Lotufo FA, Parpinelli MA, Haddad SM, Surita FG, Cecatti JG. Applying the new concept of maternal near-miss in an intensive care. Clinics. 2012;67(3):225–30.CrossRefPubMedPubMedCentral
20.
go back to reference Galvão LP, Alvim-Pereira F, Mendonça CMM, Menezes FEF, Góis KAN, Ribeiro Jr RF, et al. The prevalence of severe maternal morbidity and near miss and associated factors in Sergipe, Northeast Brazil. BMC Pregnancy Childbirth. 2014;14:25.CrossRefPubMedPubMedCentral Galvão LP, Alvim-Pereira F, Mendonça CMM, Menezes FEF, Góis KAN, Ribeiro Jr RF, et al. The prevalence of severe maternal morbidity and near miss and associated factors in Sergipe, Northeast Brazil. BMC Pregnancy Childbirth. 2014;14:25.CrossRefPubMedPubMedCentral
21.
22.
go back to reference World Health Organization. Evaluating the quality of care for severe pregnancy complications: the WHO near-miss approach for maternal health. Geneva: World Health Organization; 2011. World Health Organization. Evaluating the quality of care for severe pregnancy complications: the WHO near-miss approach for maternal health. Geneva: World Health Organization; 2011.
23.
go back to reference Goldenberg RL, McClure EM, MacGuire ER, Kamath BD, Jobe AH. Lessons for low-income regions following the reduction in hypertension-related maternal mortality in high-income countries. Int J Obstet Gynecol. 2011;113(2):91–5.CrossRef Goldenberg RL, McClure EM, MacGuire ER, Kamath BD, Jobe AH. Lessons for low-income regions following the reduction in hypertension-related maternal mortality in high-income countries. Int J Obstet Gynecol. 2011;113(2):91–5.CrossRef
24.
go back to reference Sheldon WR, Blum J, Vogel JP, Souza JP, Gülmezoglu AM, Winikoff B, et al. Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG. 2014;121 Suppl. 1:5–13.CrossRefPubMed Sheldon WR, Blum J, Vogel JP, Souza JP, Gülmezoglu AM, Winikoff B, et al. Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG. 2014;121 Suppl. 1:5–13.CrossRefPubMed
25.
go back to reference Adler AJ, Filippi V, Thomas SL, Ronsmans C. Incidence of severe acute maternal morbidity associated with abortion: a systematic review. Trop Med Int Health. 2012;17(2):177–90.CrossRefPubMed Adler AJ, Filippi V, Thomas SL, Ronsmans C. Incidence of severe acute maternal morbidity associated with abortion: a systematic review. Trop Med Int Health. 2012;17(2):177–90.CrossRefPubMed
26.
go back to reference Faúndes A, Santos LC, Carvalho M, Gras C. Post-abortion complications after interruption of pregnancy with misoprostol. Adv Contrac. 1996;12(1):1–9.CrossRef Faúndes A, Santos LC, Carvalho M, Gras C. Post-abortion complications after interruption of pregnancy with misoprostol. Adv Contrac. 1996;12(1):1–9.CrossRef
27.
go back to reference Santana DS, Cecatti JG, Parpinelli MA, Haddad SM, Costa ML, Sousa MH, et al. Severe maternal morbidity due to abortion prospectively identified in a surveillance network in Brazil. Int J Obstet Gynecol. 2012;110(1):44–8.CrossRef Santana DS, Cecatti JG, Parpinelli MA, Haddad SM, Costa ML, Sousa MH, et al. Severe maternal morbidity due to abortion prospectively identified in a surveillance network in Brazil. Int J Obstet Gynecol. 2012;110(1):44–8.CrossRef
28.
go back to reference Diniz D, Madeiro A. Cytotec and abortion: the police, the vendors and women. Cienc Saude Colet. 2012;17(7):1795–803.CrossRef Diniz D, Madeiro A. Cytotec and abortion: the police, the vendors and women. Cienc Saude Colet. 2012;17(7):1795–803.CrossRef
29.
go back to reference Zamberlin N, Romero M, Ramos S. Latin American women’s experiences with medical abortion in settings where abortion is legally restricted. Reprod Health. 2012;9:34.CrossRefPubMedPubMedCentral Zamberlin N, Romero M, Ramos S. Latin American women’s experiences with medical abortion in settings where abortion is legally restricted. Reprod Health. 2012;9:34.CrossRefPubMedPubMedCentral
30.
go back to reference Dragoman M, Sheldon WR, Qureshi Z, Blum J, Winikoff B, Ganatra B, et al. Overview of abortion cases with severe maternal outcomes in the WHO Multicountry Survey on Maternal and Newborn Health: a descriptive analysis. BJOG. 2014;121 Suppl. 1:25–31.CrossRefPubMed Dragoman M, Sheldon WR, Qureshi Z, Blum J, Winikoff B, Ganatra B, et al. Overview of abortion cases with severe maternal outcomes in the WHO Multicountry Survey on Maternal and Newborn Health: a descriptive analysis. BJOG. 2014;121 Suppl. 1:25–31.CrossRefPubMed
31.
go back to reference Pacheco AJ, Katz L, Souza AS, Amorim MA. Factors associated with severe maternal morbidity and near miss in the Sao Francisco Valley, Brazil: a retrospective, cohort study. BMC Pregnancy Childbirth. 2014;14:91.CrossRefPubMedPubMedCentral Pacheco AJ, Katz L, Souza AS, Amorim MA. Factors associated with severe maternal morbidity and near miss in the Sao Francisco Valley, Brazil: a retrospective, cohort study. BMC Pregnancy Childbirth. 2014;14:91.CrossRefPubMedPubMedCentral
33.
go back to reference Pacagnella RC, Cecatti JG, Osis MJ, Souza JP. The role of delays in severe maternal morbidity and mortality: expanding the conceptual framework. Reprod Health Matter. 2012;20(39):155–63.CrossRef Pacagnella RC, Cecatti JG, Osis MJ, Souza JP. The role of delays in severe maternal morbidity and mortality: expanding the conceptual framework. Reprod Health Matter. 2012;20(39):155–63.CrossRef
Metadata
Title
Incidence and determinants of severe maternal morbidity: a transversal study in a referral hospital in Teresina, Piaui, Brazil
Authors
Alberto Pereira Madeiro
Andréa Cronemberger Rufino
Érica Zânia Gonçalves Lacerda
Laís Gonçalves Brasil
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2015
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-015-0648-3

Other articles of this Issue 1/2015

BMC Pregnancy and Childbirth 1/2015 Go to the issue